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La Sociedad Iberoamericana de Información Científica (SIIC)
selecciona informes completos de calidad recientemente publicados en
fuentes prestigiosas del mundo indizadas por SIIC Data
Bases.
La creciente cantidad de artículos con Acceso Abierto (Open
Access) amplía la oferta de lectura pero a su vez también, entre
tanta abundancia, complica al lector en su encuentro con los estudios
fundamentales. Para facilitarlo, profesionales biomédicos de SIIC
consultan diariamente una profusa cantidad de documentos que nutrirán
Textos completos autorizados (TCA).
Las citas de la sección TCA enlazan de manera legal, autorizada y
gratuita con los textos completos (full text) publicados en
los sitios oficiales de sus respectivas fuentes.
SIIC creó, produjo y opera con exclusividad el software TCA para la
interpretación de los diversos campos documentales que integran la
estructura de un estudio: especialidad, modalidad del estudio,
fuente, fechas de publicación y selección, definición de la fuente,
limitaciones de consulta, resumen en castellano, etc.
Si bien la mayoría de los textos seleccionados corresponden a
artículos originales, revisiones y guías, los lectores también
encontrarán comentarios, entrevistas, notas periodísticas, cartas a
autores u otros textos precursores de debates o aclaratorios.
Sociedad Iberoamericana de Información Científica (SIIC) selects
complete quality-full texts which have been recently published in
renowned sources worldwide and are indexed by SIIC Data
Bases.
The increasing number of Open Access articles widens the reading offer
but, also, such myriad complicates the readers search of fundamental
articles. To facilitate this, SIIC biomedical professionals daily
consult a profuse amount of documents that will feed
Authorized Full Texts (TCA, Spanish acronym).
The citations of the AFT section link legally, authorized and free of
charge with the full texts published in the official web sites of
their corresponding sources.
SIIC created, produced and handles the AFT software that deciphers
the various documentary fields that form part of the structure of a
study: specialty, study style, source, publication and selection
dates, source definition, query limitations, summary in Spanish,
etc.
While most of the selected texts belong to original articles,
reviews, and guidelines, readers will also find commentaries,
interviews, journalistic reports, letters to authors or other texts
that may lead to discussions or clarifications.
Healthcare professionals' attitudes towards digital health interventions and perspectives on digital health inequalities in cardiometabolic care: a qualitative study.
Healthcare professionals' attitudes towards digital health interventions and perspectives on digital health inequalities in cardiometabolic care: a qualitative study.
Fuente:Bmj Open
Extracto:
HCPs described the complexities of delivering care to underserved
communities. DHIs were identified as a potential way to improve health outcomes
for some, while over-reliance risked exacerbating inequalities. HCPs made
recommendations related to design, implementation and engaging target populations
and provided practical examples to address digital health inequalities, such as
working with other sectors to take a community approach.
Claves:Cardiovascular Disease, DIABETES & ENDOCRINOLOGY, Health Equity, Telemedicine
Cita:BMJ Open 2025 Feb 26; 15 (2) : e091018.
Autor/es:Ramasawmy, Mel (a) Sunkersing, David (b)
institución:(a) Institute of Health Informatics, University College London, London, London, UK m.ramasawmy@ucl.ac.uk. (b) Wolfson Institute of Population Health, Queen Mary University of London, London, UK.
Conflicto:Competing interests: KK is the director of the University of Leicester Centre for Ethnic Health Research. AB, WH and KK are trustees of the South Asian Health Foundation. WH is also a trustee of Diabetes UK. All other authors have no completing interest to declare
Sodium valproate, a potential repurposed treatment for the neurodegeneration in Wolfram syndrome (TREATWOLFRAM)
Sodium valproate, a potential repurposed treatment for the neurodegeneration in Wolfram syndrome (TREATWOLFRAM)
Fuente:Bmj Open
Tipo de trabajo:Estudio multicéntrico
Extracto:
TRIAL REGISTRATION NUMBER:
NCT03717909.
Claves:Clinical trials, Drug Therapy, Neuro-ophthalmology, Randomised Controlled Trial
Cita:BMJ Open 2025 Feb 26; 15 (2) : e091495.
Autor/es:Dias, Renuka P (a) Brock, Kristian (b)
institución:(a) Institute of Applied Health Research, University of Birmingham, Birmingham, UK. (b) Department of Paediatric Endocrinology, Birmingham Women's and Children's Hospital, Birmingham, UK.
Conflicto:Competing interests: RPD received paid honorarium for a Sanofi clinical advisory board. SM has received payment for consultancy work from Invex Therapeutics. She has received payment for advisory boards from GenSight and Ocular Therapeutix. She has received honoraria for teaching from Teva. Grant funding has been paid to her institution from the National Institute of Health Research (NIHR131211), UK Space...
Agency and IIHUK. All other authors have no competing interests to declare.
Autor/es:Slevin, Finbar (a) Hudson, Eleanor Mae (b)
institución:(a) Leeds Institute of Medical Research, University of Leeds, Leeds, UK f.m.slevin@leeds.ac.uk. (b) Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Conflicto:Competing interests: FS is supported by a Cancer Research UK Clinical Trial Fellowship (award number 125713). LM is an associate professor funded by Yorkshire Cancer Research (award number L389LM). FWB is an associate professor funded by Yorkshire Cancer Research (award number L389FB). All other authors have no competing interest to declare.
Supportive care in cancer official journal of the Multinational Association of Supportive Care in Cancer
Selección SIIC: 7 Marzo, 2025
Supportive care in cancer official journal of the Multinational Association of Supportive Care in Cancer
The course of chemotherapy-induced peripheral neuropathy (CIPN) in hematological patients treated with vincristine, bortezomib, or lenalidomide: the NOVIT study.
The course of chemotherapy-induced peripheral neuropathy (CIPN) in hematological patients treated with vincristine, bortezomib, or lenalidomide: the NOVIT study.
Fuente:Supportive Care in Cancer Official Journal of The Multinational Association of Supportive Care in Cancer
Extracto:
This study describes the
course of CIPN in patients treated with vincristine, bortezomib, or lenalidomide
using both patient-reported and clinician-assessed outcomes. The highest
proportion of CIPN was present at cycle 3-4 and 1 month after treatment, at which
timepoints clinicians must be especially aware of CIPN. TRIAL REGISTRATION:
Registered at Clinicaltrials.gov (Trial Registration Number: NCT04393363) on
March 19, 2020.
Cita:Support Care Cancer 2025 Feb 26; 33 (3) : 225.
Autor/es:Maksten, Eva Futtrup (a) Mørch, Carsten Dahl (b)
institución:(a) Research Section, Department of Hematology, Clinical Cancer Research Center, Aalborg University Hospital, Sdr. Skovvej 15, 9000, Aalborg, Denmark. efm@rn.dk. (b) Department of Clinical Medicine, Aalborg University, Aalborg, Denmark. efm@rn.dk.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Adipokine isthmin-1 is a potential predictor of abnormal urine Na(+) excretion and insulin resistance for primary hypertension.
Adipokine isthmin-1 is a potential predictor of abnormal urine Na(+) excretion and insulin resistance for primary hypertension.
Fuente:Bmc Cardiovascular Disorders
Extracto:
Serum ISM1 levels
were positively associated with SBP and DBP. ISM1 may serve as a potential
biomarker of abnormal urine Na(+) excretion and insulin resistance in primary
hypertensive individuals. TRIAL REGISTRATION: Registered on chictr.org.cn
18/04/2024 (Registration number: ChiCTR2400083204).
Cita:BMC Cardiovasc Disord 2025 Feb 26; 25 (1) : 136.
Autor/es:Deng, Chunyan (a) Zhou, Xiaoxin (b)
institución:(a) Research Center for Metabolic and Cardiovascular, The Third Affiliated Hospital of Chongqing Medical University, Chongqing, 401120, China. (b) Department of Neurology, The Third Affiliated Hospital of Chongqing Medical University, Chongqing, 401120, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
The effect of empagliflozin on non-alcoholic fatty liver disease-related parameters in patients with type 2 diabetes mellitus: a randomized controlled trial.
The effect of empagliflozin on non-alcoholic fatty liver disease-related parameters in patients with type 2 diabetes mellitus: a randomized controlled trial.
Fuente:Bmc Endocrine Disorders
Tipo de trabajo:Estudio aleatorizado y controlado
Extracto:
These findings suggest that Empagliflozin could
be an effective adjunctive therapy for managing liver dysfunction in T2DM
patients with NAFLD. TRIAL REGISTRATION: Registered retrospectively in the
Iranian Registry of Clinical Trials (IRCT20210811052150N1) on April 16,2023
Access at https://irct.behdasht.gov.ir/search/result?query=IRCT20210811052150N1 .
Claves:Empagliflozin, Liver dysfunction, Non-alcoholic fatty liver, Type 2 diabetes mellitus
Cita:BMC Endocr Disord 2025 Feb 26; 25 (1) : 52.
Autor/es:Shojaei, Fatemeh (a) Erfanifar, Azam (b)
institución:(a) Internal Medicine, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. fateme.shojai@gmail.com. (b) Department of Endocrinology, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
The predictive function of miR-122-5p and its action mechanism by regulating PKM2 in metabolic syndrome.
The predictive function of miR-122-5p and its action mechanism by regulating PKM2 in metabolic syndrome.
Fuente:Bmc Endocrine Disorders
Tipo de trabajo:Estudio clínico
Extracto:
MiR-122-5p, a risk
factor for Mets, mediated the IR and abnormal glucose metabolism of HLCs by
negatively regulating PKM2. CLINICAL TRIAL NUMBER: Not applicable.
institución:(a) Department of Endocrinology, Shanghai Pudong New Area Gongli Hospital, Shanghai, 200135, China. (b) Nursing Department, Geriatric Hospital Affiliated with Wuhan University of Science and Technology, Wuhan, 430065, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Use of noninvasive fibrosis calculators in an urban diabetes center suggests a large burden of undetected advanced liver disease.
Use of noninvasive fibrosis calculators in an urban diabetes center suggests a large burden of undetected advanced liver disease.
Fuente:Bmc Endocrine Disorders
Tipo de trabajo:Estudio clínico
Extracto:
In our urban Diabetes Center,
utilizing the NFS calculator may detect many patients with advanced liver
disease. Further research is needed to ensure the internal validity of the
non-invasive tests in predicting liver fibrosis and to correlate these findings
with transient elastography and other imaging evidence of fatty liver disease.
CLINICAL TRIAL NUMBER: Non-applicable.
The systemic inflammation response index as risks factor for all-cause and cardiovascular mortality among individuals with respiratory sarcopenia.
The systemic inflammation response index as risks factor for all-cause and cardiovascular mortality among individuals with respiratory sarcopenia.
Fuente:Bmc Pulmonary Medicine
Extracto:
Elevated NLR, NMLR, and SIRI
are associated with increased mortality risks in respiratory sarcopenia, with
SIRI demonstrating the highest predictive power. Integrating SIRI into clinical
assessments may aid in identifying high-risk patients, allowing for targeted
interventions.
institución:(a) Department of Emergency, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, People's Republic of China. (b) School of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People's Republic of China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Department of Translational Medicine, University Federico II, Naples, Italy. (b) Department of Public Health, University of Naples Federico II, Via Sergio Pansini 5, 80131, Naples, Italy.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Blood gene expression of Toll-like receptors in SLE patients with lupus nephritis or neuropsychiatric systemic lupus erythematosus.
Blood gene expression of Toll-like receptors in SLE patients with lupus nephritis or neuropsychiatric systemic lupus erythematosus.
Fuente:Arthritis Research & Therapy
Extracto:
Our study revealed differences in TLR
expression between a lupus cohort and healthy controls. Additionally, our
analysis provides insight into specific TLR expression in cases with severe organ
manifestations, such as LN and NPSLE. The multiple mutual relationships of TLRs
demonstrate the activation of innate immunity in SLE and suggest promising
targets for future therapies or diagnostics.
Autor/es:Dudkova, Marketa (a) Petrackova, Anna (b)
institución:(a) Department of Internal Medicine III - Nephrology, Rheumatology and Endocrinology, Faculty of Medicine and Dentistry, Palacky University Olomouc and University Hospital, Olomouc, Czech Republic. (b) Department of Immunology, Faculty of Medicine and Dentistry, Palacky University Olomouc and University Hospital, Olomouc, Czech Republic.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Department of General Thoracic Surgery and Breast and Endocrinological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences. (b) Department of Surgery, Okayama City Hospital.
Conflicto:No potential conflict of interest relevant to this article was reported.
Prevalence and associated factors of adult overweight and obesity in Southwestern China.
Prevalence and associated factors of adult overweight and obesity in Southwestern China.
Fuente:Frontiers in Public Health
Extracto:
Obesity and overweight
were prevalent in Southwestern China, especially among women, those with diabetes
and/or hypertension, and those who have quitted smoking for more than 3 years.
institución:(a) Division of Cardiology, Chengdu Second People's Hospital, Chengdu, Sichuan, China. (b) Division of Cardiology, University-Town Hospital of Chongqing Medical University, Chongqing, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Association between obstructive sleep apnea hypopnea syndrome and arteriosclerosis in patients with type 2 diabetes mellitus: mediating effect of blood pressure.
Association between obstructive sleep apnea hypopnea syndrome and arteriosclerosis in patients with type 2 diabetes mellitus: mediating effect of blood pressure.
Fuente:Frontiers in Endocrinology
Extracto:
OSAHS severity elevates arteriosclerosis risk in T2DM patients. Blood
pressure is a partial intermediary in this effect.
Claves:arteriosclerosis, cardiovascular risk, mediation effect, obstructive sleep apnea hypopnea syndrome, type 2 diabetes mellitus, vascular health
institución:(a) Department of Endocrinology, The Third Affiliated Hospital of Soochow University, Changzhou, China. (b) Department of Endocrinology, The Third Affiliated Hospital of Soochow University, Changzhou, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Case report: Hypoparathyroidism-sensorineural hearing loss-renal dysplasia without febrile seizures: a novel mutation in the GATA3 gene.
Case report: Hypoparathyroidism-sensorineural hearing loss-renal dysplasia without febrile seizures: a novel mutation in the GATA3 gene.
Fuente:Frontiers in Endocrinology
Extracto:
Early genetic testing
should be prioritized, and regular monitoring of kidney development and hearing
status is essential. The reported case, featuring the novel GATA3 gene mutation
c.800G>T (p.C267F), contributes to the enrichment of the genetic database.
institución:(a) Department of Endocrinology, Changsha Hospital of Hunan Normal University, Changsha, Hunan, China. (b) Department of Endocrinology, The Fourth Hospital of Changsha, Changsha, Hunan, China.
Conflicto:The authors declare that the research was conducted without any commercial or financial relationships that could be construed as a potential conflict of interest.
Global Prevalence of Anxiety in Gastroenterology and Hepatology Outpatients
Global Prevalence of Anxiety in Gastroenterology and Hepatology Outpatients
Fuente:Current Gastroenterology Reports
Tipo de trabajo:Revisión sistemática
Extracto:
Anxiety is thus common amongst
gastroenterology and hepatology outpatients, and so it is important that careful
consideration be given to the identification and management of anxiety in these
settings.
Cita:Curr Gastroenterol Rep 2025 Feb 27; 27 (1) : 17.
Autor/es:Storer, Ben (a) Holden, Monique (b)
institución:(a) Clinical Research Department, The Black Dog Institute, Sydney, Australia. (b) Clinical Research Department, The Black Dog Institute, Sydney, Australia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Immunoinformatic evaluation for the development of a potent multi-epitope vaccine against bacterial vaginosis caused by Gardnerella vaginalis.
Immunoinformatic evaluation for the development of a potent multi-epitope vaccine against bacterial vaginosis caused by Gardnerella vaginalis.
Fuente:Plos One
Extracto:
According to the findings, the candidate
multi-epitope vaccine has stable structural features. It also has the potential
to stimulate long-term immunity in the host, but wet-lab validation is needed to
justify it.
Cita:PLoS One 2025; 20 (2) : e0316699.
Autor/es:Motamedi, Hamid (a) Shoja, Saeed (b)
institución:(a) Asadabad School of Medical Sciences, Asadabad, Iran. (b) Asadabad School of Medical Sciences, Asadabad, Iran.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Pharmacological interventions for addressing pediatric and adolescent obesity
Pharmacological interventions for addressing pediatric and adolescent obesity
Fuente:Plos One
Tipo de trabajo:Revisión sistemática
Extracto:
The study found that semaglutide outperformed other
AOMs in reducing BMI and additional weight-related outcomes in children and
adolescents with obesity, while PHEN/TPM showed comparable efficacy.
Cita:PLoS One 2025; 20 (2) : e0314787.
Autor/es:Yang, Shuo (a) Xin, Shuangqing (b)
institución:(a) Department of Endocrinology and Metabolism, The People's Hospital of China Medical University, The People's Hospital of Liaoning Province, Shenyang, China. (b) Department of Endocrinology and Metabolism, The People's Hospital of China Medical University, The People's Hospital of Liaoning Province, Shenyang, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Management of adrenocortical carcinoma in Slovenia: a real-life analysis of histopathologic markers, treatment patterns, prognostic factors, and survival.
Management of adrenocortical carcinoma in Slovenia: a real-life analysis of histopathologic markers, treatment patterns, prognostic factors, and survival.
Fuente:Radiology and Oncology
Extracto:
The
5-year DSS of our ENSAT II patients was worse than reported in contemporary
cohorts. Suboptimal surgery and inconsistent adjuvant therapy with mitotane might
have contributed to this outcome. Better outcomes of this rare disease might be
accomplished with dedicated teams including various specialties, working towards
optimal staging, diagnostic and therapeutic measures.
institución:(a) 1Department of Medical Oncology, Institute of Oncology Ljubljana, Ljubljana, Slovenia. (b) 2Institute of Pathology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Construction of a prediction model for coronary heart disease in type 2 diabetes mellitus: a cross-sectional study.
Construction of a prediction model for coronary heart disease in type 2 diabetes mellitus: a cross-sectional study.
Fuente:Scientific Reports
Extracto:
This model facilitates early intervention and personalized
treatment for hypertension, smoking, neuropathy, vascular complications, cerebral
infarction, bilateral lower extremity arteriosclerosis, microalbuminuria, and
elevated uric acid levels, improving overall health outcomes for patient.
Cita:Sci Rep 2025 Feb 27; 15 (1) : 7003.
Autor/es:Zhang, Huiling (a) Shi, Hui (b)
institución:(a) Laboratory of Geriatric Nursing and Health, School of Nursing, Anhui Univerity of Traditional Chinese Medicine, No.103 Meishan Road, Hefei, 230012, Anhui Province, China. 1101090886@qq.com. (b) Laboratory of Geriatric Nursing and Health, School of Nursing, Anhui Univerity of Traditional Chinese Medicine, No.103 Meishan Road, Hefei, 230012, Anhui Province, China. ymf149@126.com.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
