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Liver international official journal of the International Association for the Study of the Liver
Selección SIIC: 13 Febrero, 2025
Liver international official journal of the International Association for the Study of the Liver
The Global Burden of Cirrhosis and Other Chronic Liver Diseases in 2021.
The Global Burden of Cirrhosis and Other Chronic Liver Diseases in 2021.
Fuente:Liver International Official Journal of The International Association For The Study of The Liver
Extracto:
Age-adjusted
deaths related to cirrhosis and other chronic liver diseases are declining.
However, the age-adjusted incidence of cirrhosis and other chronic liver diseases
is increasing, driven by increases in the incidence of MASH.
Claves:chronic liver disease, cirrhosis, global burden
Cita:Liver Int 2025 Mar; 45 (3) : e70001.
Autor/es:Tham, Ethan Kai Jun (a) Tan, Darren Jun Hao (b)
institución:(a) Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. (b) Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Conflicto:C.H.N. has served as a consultant for Boxer Capital. R.L. serves as a consultant to Aardvark Therapeutics, Altimmune, Anylam/Regeneron, Amgen, Arrowhead Pharmaceuticals, AstraZeneca, Bristol‐Myer Squibb, CohBar, Eli Lilly, Galmed, Gilead, Glympse Bio, Hightide, Inipharma, Intercept, Inventiva, Ionis, Janssen Inc., Madrigal, Metacrine Inc., NGM Biopharmaceuticals, Novartis, Novo Nordisk, Merck, Pfizer, Sagimet, Theratechnologies, 89 bio, Terns Pharmaceuticals and Viking Therapeutics. In addition,...
n, his institutions received research grants from Arrowhead Pharmaceuticals, Astrazeneca, Boehringer‐Ingelheim, Bristol‐Myers Squibb, Eli Lilly, Galectin Therapeutics, Galmed Pharmaceuticals, Gilead, Intercept, Hanmi, Intercept, Inventiva, Ionis, Janssen, Madrigal Pharmaceuticals, Merck, NGM Biopharmaceuticals, Novo Nordisk, Merck, Pfizer, Sonic Incytes and Terns Pharmaceuticals. D.H., co‐founder of LipoNexus Inc., has served as an advisory board member for Gilead. All other authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Effects of Age and Sex on Systemic Inflammation and Cardiometabolic Function in Individuals With Type 2 Diabetes.
Effects of Age and Sex on Systemic Inflammation and Cardiometabolic Function in Individuals With Type 2 Diabetes.
Fuente:Journal of The American Heart Association
Extracto:
The
pathophysiological manifestations of T2D on vascular function and aerobic
exercise capacity are distinct in older men and women, and this may reflect
underlying differences in vascular and myocardial aging in the presence of T2D.
Claves:aerobic exercise capacity, cardiovascular aging, inflammatory biomarkers, sex differences, type 2 diabetes
Cita:J Am Heart Assoc 2025 Feb 4; 14 (3) : e037863.
Autor/es:Dushay, Jody (a) Rickers, Eva S (b)
institución:(a) Division of Endocrinology Beth Israel Deaconess Medical Center, Harvard Medical School Boston MA. (b) Department of Radiology Brigham and Women's Hospital, Harvard Medical School Boston MA.
Exploration of vitamin D hydroxy metabolites C3 epimers in patients with cardiovascular disease: an observational study.
Exploration of vitamin D hydroxy metabolites C3 epimers in patients with cardiovascular disease: an observational study.
Fuente:Bioscience Reports
Extracto:
While the mechanism of how vitamin D epimeric forms influence
diseases remains unclear, we recommend maintaining 25(OH)D3 levels above 20
ng/mL.
institución:(a) Department of Physical Pharmacy and Pharmacokinetics, Faculty of Pharmacy, Poznan University of Medical Sciences, 3 Rokietnicka Street, 60-806 Poznan, Poland. (b) Doctoral School, Poznan University of Medical Sciences, Bukowska 70 Street, 60-812 Poznan, Poland.
Sarcopenia is not associated with hypertension, but sarcopenic obesity increases risk of hypertension
Sarcopenia is not associated with hypertension, but sarcopenic obesity increases risk of hypertension
Fuente:Frontiers in Public Health
Tipo de trabajo:Estudio de cohortes
Extracto:
There is no significant
correlation between sarcopenia and hypertension, but obesity and sarcopenic
obesity increase the risk of hypertension. Targeted management of middle-aged and
older people with sarcopenic obesity is needed in public health efforts.
institución:(a) Department of Geriatrics, The Third People's Hospital of Yunnan Province, Kunming, Yunnan, China. (b) Department of Endocrinology, The First People's Hospital of Yunnan Province, Kunming, Yunnan, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Psychological burden in patients with sellar masses under conservative and surgical management.
Psychological burden in patients with sellar masses under conservative and surgical management.
Fuente:Neurosurgical Review
Extracto:
ACTH-producing adenomas
and manifest nasal symptoms were associated with higher psychological distress.
Claves:Anxiety, Depression, Pituitary adenoma, Psychological distress, Quality of life, Sellar mass
Cita:Neurosurg Rev 2025 Jan 30; 48 (1) : 104.
Autor/es:Kalasauskas, Darius (a) Ernst, Andreas (b)
institución:(a) Department of Neurosurgery, University Medical Centre, Johannes Gutenberg University, Mainz, Germany. Darius.Kalasauskas@unimedizin-mainz.de. (b) Department of Neurosurgery, University Medical Centre, Johannes Gutenberg University, Mainz, Germany.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Obesity phenotypes and dyslipidemia in adults from four African countries: An H3Africa AWI-Gen study.
Obesity phenotypes and dyslipidemia in adults from four African countries: An H3Africa AWI-Gen study.
Fuente:Plos One
Tipo de trabajo:Metanálisis
Extracto:
Obesity in all forms may drive a dyslipidaemia epidemic in SSA with
men and transitioned societies at a higher risk. Targeted interventions to
control the epidemic should focus on health promoting and improved access to
screening services.
Cita:PLoS One 2025; 20 (1) : e0316527.
Autor/es:Nonterah, Engelbert A (a) Agongo, Godfred (b)
institución:(a) Navrongo Health Research Centre, Ghana Health Service, Navrongo, Ghana. (b) Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Acquired hypothyroidism, iodine status and hearing impairment in adults: A pilot study.
Acquired hypothyroidism, iodine status and hearing impairment in adults: A pilot study.
Fuente:Plos One
Extracto:
We did not observe any hearing
impairment in adults with acquired hypothyroidism, and there were no associations
found between hearing impairment and the severity of hypothyroidism or iodine
status. However, some forms of hearing impairment, mostly mild, were very common
in both studied groups.
institución:(a) Institute of Endocrinology, Prague, Czech Republic. (b) Department of Internal medicine, Faculty Hospital Kralovske Vinohrady and Third Faculty of Medicine, Charles University, Prague, Czech Republic.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Extracto:
With protocol adjustments, PET/MRI might be utilized in the future
for preoperative staging of esophageal cancer. CLINICAL TRIAL NUMBER: N/A.
institución:(a) Universal Scientific Education and Research Network (USERN), Tehran, Iran. (b) School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
The MTNR1B Rs724030 variant is associated with islet function and women waist-to-hip ratio in healthy subjects.
The MTNR1B Rs724030 variant is associated with islet function and women waist-to-hip ratio in healthy subjects.
Fuente:Frontiers in Endocrinology
Extracto:
The MTNR1B
rs724030 variant contributes to glycemic traits and islet function, and its
effects have sex dimorphisms in the NGT individuals after stratifying by WHR. All
these findings provide a basis for accurately assessing islet function in healthy
populations and offer a new perspective on precision prevention.
Claves:MTNR1B, islet function, prediabetes, sex dimorphisms, variant
institución:(a) Department of Endocrinology and Metabolism, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China. (b) Department of Endocrinology and Metabolism, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Causal effects of circulating immune cells on coronary atherosclerosis: Evidence from Mendelian randomization.
Causal effects of circulating immune cells on coronary atherosclerosis: Evidence from Mendelian randomization.
Fuente:Medicine
Extracto:
This provides a
genetic explanation for the role of specific immune cells in inducing and
exacerbating coronary artery disease and offers new ideas for the exploration of
immune markers and immune-targeted drugs.
Cita:Medicine (Baltimore) 2025 Jan 31; 104 (5) : e41361.
Autor/es:Yang, Xinyu (a) Yu, Yunfeng (b)
institución:(a) Department of Endocrinology, The First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan, China. (b) School of Traditional Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Clinical Trials Research Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, UK. (b) Clinical Trials Research Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, UK.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Extracto:
Body composition is
associated with dietary CO(2) emissions. The higher total body water, fat free
mass, and body weight, the higher the dietary CO(2) emissions were, following a
linear relationship. CLINICAL TRIAL REGISTRATION:
http://www.isrctn.com/ISRCTN89898870, ISRCTN89898870.
Claves:CO2 emissions, anthropometry, body composition, environment, sustainable diets
institución:(a) CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III (ISCIII), Madrid, Spain. (b) Research Group on Community Nutrition & Oxidative Stress, University of Balearic Islands-IUNICS, Palma de Mallorca, Spain.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
A clinical decision model for failed adrenal vein sampling in primary aldosteronism.
A clinical decision model for failed adrenal vein sampling in primary aldosteronism.
Fuente:Frontiers in Endocrinology
Tipo de trabajo:Estudio de cohortes
Extracto:
Utilizing the LAV/IVC index, over 70% of unsuccessful AVS procedures
due to failed right adrenal cannulation could be interpreted with over 90%
certainty regarding the PA subtype, preventing unnecessary resampling and aiding
in determining the preferred treatment.
Autor/es:Ter Haar, Sophie N M (a) van Goor, Sofie J (b)
institución:(a) Department of Medicine, Division of Endocrinology and Metabolism, Leiden University Medical Center, Leiden, Netherlands. (b) Department of Medicine, Division of Endocrinology and Metabolism, Leiden University Medical Center, Leiden, Netherlands.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Pre-trained convolutional neural network with transfer learning by artificial illustrated images classify power Doppler ultrasound images of rheumatoid arthritis joints.
Pre-trained convolutional neural network with transfer learning by artificial illustrated images classify power Doppler ultrasound images of rheumatoid arthritis joints.
Fuente:The Journal of International Medical Research
Tipo de trabajo:Estudio clínico
Extracto:
Artificial images may be useful for
training VGG-16. The present novel approach of using artificial images as an
alternative to actual images for training a CNN has the potential to be applied
in medical imaging fields that face difficulties in collecting real clinical
images.
Cita:J Int Med Res 2025 Feb; 53 (2) : 3000605251318195.
Autor/es:Fukae, Jun (a) Amasaki, Yoshiharu (b)
institución:(a) Department of Rheumatology, Kuriyama Red Cross Hospital, Hokkaido, Japan. RINGGOLD: 202333 (b) Department of Rheumatology, Kuriyama Red Cross Hospital, Hokkaido, Japan. RINGGOLD: 202333
Conflicto:Declaration of conflicting interestThe authors declare that there is no conflict of interest.
Causal relationships between plasma lipidome and diabetic neuropathy: a Mendelian randomization study.
Causal relationships between plasma lipidome and diabetic neuropathy: a Mendelian randomization study.
Fuente:Frontiers in Endocrinology
Tipo de trabajo:Estudio clínico
Extracto:
Our research
linked certain lipid species with diabetic neuropathy risk, suggesting that
targeting lipids could be a therapeutic strategy in clinical trials addressing
this condition.
institución:(a) Department of Endocrinology, First People's Hospital of Kunshan, Kunshan, Jiangsu, China. (b) Department of Emergency Medicine, First People's Hospital of Kunshan, Kunshan, Jiangsu, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Prevalence and predictive factors of testosterone-induced erythrocytosis: a retrospective single center study.
Prevalence and predictive factors of testosterone-induced erythrocytosis: a retrospective single center study.
Fuente:Frontiers in Endocrinology
Extracto:
TIE appears to be frequent and does not only present within the first year of
therapy which indicates a close follow-up of laboratory values within the first
year followed by annual controls. Baseline BMI and baseline HCT measurement
should be considered in risk stratification of TIE development.
institución:(a) Department of Internal Medicine, Division of Endocrinology, Diabetes and Clinical Nutrition, Luzerner Kantonsspital, Lucerne, Switzerland. (b) Institute for Implementation Science in Healthcare, University of Zurich, Zurich, Switzerland.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Socio-demographic and clinical determinants of self-care in adults with type 2 diabetes: a multicenter cross-sectional study in Zhejiang province, China.
Socio-demographic and clinical determinants of self-care in adults with type 2 diabetes: a multicenter cross-sectional study in Zhejiang province, China.
Fuente:Bmc Public Health
Extracto:
INTERPRETATION: The findings of
this study provide invaluable insights into the factors affecting self-care among
Chinese adults with type 2 diabetes. By enhancing self-care self-efficacy and
participating in diabetes self-management education, healthcare providers can
develop tailored self-care interventions to improve diabetes care, particularly
for adults with type 2 diabetes who are female, belong to minority groups, have
complications, use insulin, or reside in the southwest of Zhejiang province.
Claves:Self-care, Self-care self-efficacy, Self-management, Type 2 diabetes mellitus
Cita:BMC Public Health 2025 Jan 31; 25 (1) : 397.
Autor/es:Lan, Xuefen (a) Ji, Xiaozhen (b)
institución:(a) Nursing Department, Medicine College, Lishui University, Lishui, Zhejiang, China. (b) Department of Endocrinology, Lishui People's Hospital, Lishui, Zhejiang, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Multiomics unravels the complexity of male obesity: a prospective observational study.
Multiomics unravels the complexity of male obesity: a prospective observational study.
Fuente:Journal of Translational Medicine
Extracto:
Combining clinical, biochemical, and molecular markers allows
adequate stratification of metabolic risk in men with obesity and provides novel
tools for personalized care.
Claves:Bariatric surgery, Hypogonadism, Male obesity, Metabolic risk stratification, Transcriptomics
Cita:J Transl Med 2025 Jan 30; 23 (1) : 138.
Autor/es:Papadakis, Georgios E (a) Favre, Lucie (b)
institución:(a) Department of Endocrinology, Diabetology and Metabolism, Lausanne University Hospital, Avenue de la Sallaz 8, CH-1011, Lausanne, Switzerland. (b) Faculty of Biology and Medicine, University of Lausanne, Rue du Bugnon 21, CH-1005, Lausanne, Switzerland.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Correlation of diabetes and adverse outcomes in hospitalized COVID-19 patients admitted to a tertiary hospital in China during a small-scale COVID-19 outbreak.
Correlation of diabetes and adverse outcomes in hospitalized COVID-19 patients admitted to a tertiary hospital in China during a small-scale COVID-19 outbreak.
Fuente:Peerj
Tipo de trabajo:Estudio de cohortes
Extracto:
Infection with COVID-19 on the basis
of diabetes can significantly increase mortality, which was further associated
with diabetes control indicators.
institución:(a) Department of Endocrinology, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China. (b) Department of Endocrinology, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
CAVIN-2 positively correlates with diabetic PAD and promotes LDL transcytosis by inhibiting eNOS activation.
CAVIN-2 positively correlates with diabetic PAD and promotes LDL transcytosis by inhibiting eNOS activation.
Fuente:Annals of Medicine
Extracto:
CAVIN-2 was positively correlated with DM-PAD and promoted LDL
transcytosis through the inhibition of eNOS activation, contributing to
atherosclerosis development. This study provided clinical evidence linking
CAVIN-2 to diabetic PAD and suggested its potential as a biomarker for disease
progression.
Claves:CAVIN-2, LDL transcytosis, atherosclerosis, peripheral artery disease, type 2 diabetes
Cita:Ann Med 2025 Dec; 57 (1) : 2457526.
Autor/es:Wang, Li (a) Song, Yi (b)
institución:(a) Department of Endocrinology, Institute of Geriatric Medicine, Liyuan Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China. (b) Department of Endocrinology, Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Conflicto:No potential conflict of interest was reported by the authors.
