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reviews, and guidelines, readers will also find commentaries,
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Development and validation of a predictive model for carotid atherosclerosis in postmenopausal women.
Development and validation of a predictive model for carotid atherosclerosis in postmenopausal women.
Fuente:Scientific Reports
Extracto:
This model
provides a scientific basis for early risk assessment and personalized
interventions for menopausal women, guiding future research on related biological
mechanisms.
institución:(a) Centre of Health Management, Shenzhen Hospital of Southern Medical University, 1333 Xinhu Road, Shenzhen, 518101, China. liujing1833@126.com. (b) Department of Endocrinology and Metabolism, Shenzhen Hospital of Southern Medical University, 1333 Xinhu Road, Shenzhen, 518101, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Impact of steatotic liver disease subtypes, sarcopenia, and fibrosis on all-cause and cause-specific mortality
Impact of steatotic liver disease subtypes, sarcopenia, and fibrosis on all-cause and cause-specific mortality
Fuente:Bmc Gastroenterology
Tipo de trabajo:Estudio de cohortes
Extracto:
SLD definition identified a
more homogeneous group with metabolically hepatic steatosis at higher risks of
mortality. MASLD or MASLD-related advanced fibrosis and sarcopenia additively
increased mortality.
institución:(a) Department of Geriatrics, The First Affiliated Hospital of Fujian Medical University, No. 20 Chazhong Road, Fuzhou, 350005, Fujian, China. (b) Branch of National Clinical Research Center for Aging and Medicine, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
The new definition of metabolic syndrome including hyperuricemia improves its prognostic value: results from NHANES database.
The new definition of metabolic syndrome including hyperuricemia improves its prognostic value: results from NHANES database.
Fuente:Bmc Cardiovascular Disorders
Extracto:
The inclusion of hyperuricemia in the MetS
criteria could identify a larger proportion of individuals at metabolic risk,
thereby facilitating early management to prevent long-term adverse events.
Claves:Hyperuricemia, Metabolic syndrome, Mortality, Prognostic value
Cita:BMC Cardiovasc Disord 2025 Feb 11; 25 (1) : 93.
Autor/es:Zhang, Zhichao (a) Pang, Yuanxin (b)
institución:(a) Department of Electrocardiogram Room, Suzhou Ninth People's Hospital, Suzhou Ninth Hospital, Soochow University, Suzhou, China. (b) Department of Endocrinology, Suzhou Ninth People's Hospital, Suzhou Ninth Hospital Affiliated to Soochow University, Suzhou, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Identification of biomarkers for the diagnosis of type 2 diabetes mellitus with metabolic associated fatty liver disease by bioinformatics analysis and experimental validation.
Identification of biomarkers for the diagnosis of type 2 diabetes mellitus with metabolic associated fatty liver disease by bioinformatics analysis and experimental validation.
Fuente:Frontiers in Endocrinology
Extracto:
The sensitivity and accuracy in diagnosing and
predicting T2DM-associated MAFLD can be greatly improved using SERPINB2 and
TNFRSF1A. These genes may significantly influence the development of
T2DM-associated MAFLD, offering new diagnostic options for patients with T2DM
combined with MAFLD.
institución:(a) Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China. (b) Guangxi Key Laboratory of Precision Medicine in Cardio-Cerebrovascular Diseases Control and Prevention, First Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi, China.
Conflicto:The research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Exploring the levels of variation, inequality and use of physical activity intervention referrals in England primary care from 2017-2020
Exploring the levels of variation, inequality and use of physical activity intervention referrals in England primary care from 2017-2020
Fuente:Bmj Open
Tipo de trabajo:Estudio de cohortes
Extracto:
Our findings identified statistically significant variation and underuse of
physical activity referrals in primary care in England for individuals at risk of
CVD for different population subgroups, especially different ethnicities and age
groups, across different regions of England and across time, with the COVID-19
pandemic exerting a significant negative impact on referral rates.
Claves:Cardiovascular Disease, DIABETES & ENDOCRINOLOGY, Health Equity, Health informatics, PREVENTIVE MEDICINE, Primary Care
Cita:BMJ Open 2025 Feb 12; 15 (2) : e086297.
Autor/es:Jani, Anant (a) Liyanage, Harshana (b)
institución:(a) Heidelberg Institute for Global Health, Heidelberg University, Heidelberg, Baden-Württemberg, Germany. (b) Department of Health and Social Care, UK Health Security Agency, London, UK.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Extracto:
Additionally, we plan to obtain a more comprehensive genomic analysis on the
entire cohort, ensuring greater research interest and investigation into the
underlying genetic factors that contribute to disease susceptibility in this
cohort.
Claves:Community Participation, Community-Based Participatory Research, Health Equity, Latin America, REGISTRIES
Cita:BMJ Open 2025 Feb 11; 15 (2) : e093445.
Autor/es:Zarrugh, Emmil (a) Girardo, Marlene E (b)
institución:(a) Center for Individualized Medicine, Mayo Clinic Arizona, Scottsdale, Arizona, USA. (b) Department of Quantitative Health Sciences, Mayo Clinic, Rochester, New York, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Case report: Clinical characteristics and Genetical analysis of HSD11B2 in three Chinese children with apparent mineralocorticoid excess: a case series.
Case report: Clinical characteristics and Genetical analysis of HSD11B2 in three Chinese children with apparent mineralocorticoid excess: a case series.
Fuente:Frontiers in Endocrinology
Tipo de trabajo:Revisión
Extracto:
This study presents the diagnostic
and treatment experiences of three Chinese pediatric patients with AME type I.
Through our analysis, four novel variants of the HSD11B2 gene were identified,
thereby enhancing the genotype-phenotype spectrum associated with AME. Early
genetic testing in patients suspected of having AME is beneficial for
facilitating prompt diagnosis and the implementation of standardized treatment
protocols. Such measures are essential for the prevention or mitigation of target
organ damage, as well as for the reduction of associated morbidity and mortality.
Claves:apparent mineralocorticoid excess, case series, hypokalemia, low-renin hypertension, renal calcification
institución:(a) Department of Endocrinology, Genetics, Metabolism, Beijing Children's Hospital, Capital Medical University, National Centre for Children's Health, Beijing, China. (b) Ministry of Education (MOE) Key Laboratory of Major Diseases in Children, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
GLP-1RA and SGLT2i utilization in people with type 2 diabetes with atherosclerotic cardiovascular disease (ASCVD) or at high risk of ASCVD in the Gulf Region: Results from the PACT-MEA studys.
GLP-1RA and SGLT2i utilization in people with type 2 diabetes with atherosclerotic cardiovascular disease (ASCVD) or at high risk of ASCVD in the Gulf Region: Results from the PACT-MEA studys.
Fuente:Saudi Medical Journal
Tipo de trabajo:Revisión
Extracto:
Despite these cardioprotective agents being recommended by
guidelines, the study findings suggest a suboptimal use of GLP-1RA and SGLT2i in
a real-world setting.
Autor/es:Al-Dahi, Waleed A (a) Khalaf, Saeed H (b)
institución:(a) From the Department of Internal Medicine (Al-Dahi), Mubarak Hospital, Al Jairiyah; from the Department of Pediatric Endocrinology (Al Kandari), Farwaniya Hospital; from the Department of Endocrinology (Al Kandari, Abdalla), Dasman Diabetes Institute, Dasma; from the Department of Primary Care (Abdalla, Alfadehla) Yarmouk Primary Health Care Centre, Al Yarmūk; from the Department of Medical Affairs (AlAlami, Subbarao, Chetty), Novo Nordisk Gulf Cluster, Salmiya, Kuwait; from the Department of Endocrinology (Khalaf), Salmaniya Medical Complex, Manama; from the Department of Endocrinology (AlRomaihi), Awali Hospital, Awali; Department of Internal Medicine (Alamuddin), King Hamad University Hospital, Adliya; from the Department of Endocrinology (Abdulla), Bahrain Defence Force Hospital, West Riffa, Bahrain; and from the Department of Endocrinology (Jayyousi, Siddique), Hamad Medical Corporation, Doha, Qatar. (b) From the Department of Internal Medicine (Al-Dahi), Mubarak Hospital, Al Jairiyah; from the Department of Pediatric Endocrinology (Al Kandari), Farwaniya Hospital; from the Department of Endocrinology (Al Kandari, Abdalla), Dasman Diabetes Institute, Dasma; from the Department of Primary Care (Abdalla, Alfadehla) Yarmouk Primary Health Care Centre, Al Yarmūk; from the Department of Medical Affairs (AlAlami, Subbarao, Chetty), Novo Nordisk Gulf Cluster, Salmiya, Kuwait; from the Department of Endocrinology (Khalaf), Salmaniya Medical Complex, Manama; from the Department of Endocrinology (AlRomaihi), Awali Hospital, Awali; Department of Internal Medicine (Alamuddin), King Hamad University Hospital, Adliya; from the Department of Endocrinology (Abdulla), Bahrain Defence Force Hospital, West Riffa, Bahrain; and from the Department of Endocrinology (Jayyousi, Siddique), Hamad Medical Corporation, Doha, Qatar.
The low FODMAP diet in adolescents functional abdominal in a non-guided setting
The low FODMAP diet in adolescents functional abdominal in a non-guided setting
Fuente:European Journal of Pediatrics
Tipo de trabajo:Estudio de cohortes
Extracto:
The low FODMAP
diet in a non-guided setting, mimicking clinical practice, yielded treatment
success in almost 30% adolescents with IBS and 17% in FAP-NOS, suggesting it may
not be the first treatment option for these patients. TRIAL REGISTRATION:
EUCTR2015-003293-32-NL. WHAT IS KNOWN: • Irritable bowel syndrome (IBS) and
functional abdominal pain-not otherwise specified (FAP-NOS) are common disorders
in children which negatively impact quality of life. • While a diet low in
fermentable oligosaccharides, disaccharides, monosaccharides, and polyols
(FODMAPs) has demonstrated effectiveness in adult IBS, its efficacy in pediatric
IBS and FAP-NOS remains uncertain. • Clinical application of the low FODMAP diet
often occurs without dietician consultation, contrary to controlled trial
settings. WHAT IS NEW: • The low FODMAP diet, without dietician guidance,
resulted in treatment success in almost 30% of adolescents with IBS and only 17%
with FAP-NOS. • With only 15.7% of participants achieving adequate relief of
IBS/FAP-NOS symptoms, the non-guided low FODMAP diet may not be the first
treatment option for pediatric IBS and FAP-NOS.
institución:(a) Emma's Children Hospital, Amsterdam UMC, Location AMC, University of Amsterdam, Pediatric Gastroenterology, Hepatology and Nutrition, Room C2-312, PO Box 22700, 1100 DD, Amsterdam, The Netherlands. (b) Amsterdam Reproduction & Development Research Institute, Amsterdam University Medical Centers, Location Academic Medical Center/Emma Children's Hospital, Amsterdam, The Netherlands.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Department of General Medicine, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama-city, Kanagawa pref, Japan. e103007c@yokohama-cu.ac.jp. (b) Department of General Medicine, Yokohama City University Medical Center, Yokohama, Kanagawa, Japan. e103007c@yokohama-cu.ac.jp.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Assessing Dynamic Cognitive Function in the Daily Lives of Youths With and Without Type 1 Diabetes: Usability Study.
Assessing Dynamic Cognitive Function in the Daily Lives of Youths With and Without Type 1 Diabetes: Usability Study.
Fuente:Jmir Formative Research
Extracto:
The results suggest that using the ARC smartphone
app to assess dynamic cognitive functions in youths with and without T1D is
feasible. Further, we showed CGM-derived glycemic variability at temporally
associated timeframes of dynamic cognitive assessments. The next steps include
using ecological momentary assessment in a fully powered study to determine the
relationship between short-term glycemic control and cognition in youths with
T1D.
Claves:CGM, EMA, acceptability, ambulatory, app, application, assessment, cognitive test, continuous glucose monitoring, daily lives, diabetes, ecological momentary assessment, environmental factor, feasibility study, glycemic control, mobile phone, phone, pilot study, smartphone, type 1 diabetes, young, youth
Cita:JMIR Form Res 2025 Feb 11; 9 : e60275.
Autor/es:Ray, Mary Katherine (a) Fleming, Jorie (b)
institución:(a) Department of Psychiatry, Washington University in St. Louis, 660 S. Euclid Avenue, St. Louis, MO, 63110, United States, 1 3142738322. (b) Department of Radiology, Washington University in St. Louis, St. Louis, MO, United States.
Immune imbalance in the pre-ovulatory follicular microenvironment of overweight and obese women during IVF.
Immune imbalance in the pre-ovulatory follicular microenvironment of overweight and obese women during IVF.
Fuente:Journal of Ovarian Research
Extracto:
Overweight and obesity can disrupt immune hemostasis in the
pre-ovulatory follicular microenvironment, potentially leading to adverse effects
on assisted reproductive outcomes.
Claves:Cholesterol, IVF, Obesity, Pre-ovulatory follicular microenvironment, T cells
Cita:J Ovarian Res 2025 Feb 5; 18 (1) : 23.
Autor/es:Liu, Yang (a) Zhao, Yiran (b)
institución:(a) Obstetrics and Gynecology Hospital, Institute of Reproduction and Development, Fudan University, Shanghai, 200011, China. (b) Obstetrics and Gynecology Hospital, Institute of Reproduction and Development, Fudan University, Shanghai, 200011, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Health expectations an international journal of public participation in health care and health policy
Selección SIIC: 13 Febrero, 2025
Health expectations an international journal of public participation in health care and health policy
Developing a Quality Improvement Framework to Enhance the Health System User Experience for Individuals Living With Type 1 Diabetes: The Reshape T1D Study.
Developing a Quality Improvement Framework to Enhance the Health System User Experience for Individuals Living With Type 1 Diabetes: The Reshape T1D Study.
Fuente:Health Expectations An International Journal of Public Participation in Health Care and Health Policy
Extracto:
Our findings highlight how important health system user
suggestions are for more equitable, accessible, and empathetic healthcare for
individuals living with T1D. Further work is needed to explore health system user
experiences with clinicians and healthcare administrators to effectively carry
out T1D clinical quality improvement.
Claves:community‐based participatory research, diabetes, endocrinology, patient‐centered care, qualitative, type 1 diabetes
Cita:Health Expect 2025 Feb; 28 (1) : e70172.
Autor/es:Boisvenue, Jamie (a) Elezzabi, Youssef A (b)
institución:(a) Department of Medicine, Faculty of Medicine & Dentistry, College of Health Sciences, University of Alberta, Edmonton, Alberta, Canada. (b) Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada.
Conflicto:JB received studentship funding from Diabetes Action Canada, the Government of Alberta, Alberta Diabetes Institute, Alberta Physician Learning Program, Alberta Strategy for Patient‐Oriented Research, and the University of Alberta School of Public Health for the duration of this project. YE received studentship funding from the Northern Alberta Clinical Trials & Research Centre for this project. KG, HH, RM, and YE...
YE received patient honoraria. KG, HH, KY, and JB received speaker fees related to the submitted work. PS is supported by the Alberta Academic Medicine Health Services Program and holds the Charles A Allard Chair in Diabetes Research outside of the submitted work. RY reports grants from the Alberta Health Services Diabetes Obesity and Nutrition Strategic Clinical Network and Alberta Diabetes Institute for this work and personal fees from Dexcom and Novo Nordisk outside the submitted work.
Gynecological endocrinology the official journal of the International Society of Gynecological Endocrinology
Selección SIIC: 13 Febrero, 2025
Gynecological endocrinology the official journal of the International Society of Gynecological Endocrinology
Signs and symptoms of vulvovaginal atrophy (VVA) in clinical practice - the possible involvement of thyroid autoimmunity in genitourinary syndrome of menopause (GSM).
Signs and symptoms of vulvovaginal atrophy (VVA) in clinical practice - the possible involvement of thyroid autoimmunity in genitourinary syndrome of menopause (GSM).
Fuente:Gynecological Endocrinology The Official Journal of The International Society of Gynecological Endocrinology
Extracto:
This study suggests that thyroid ADs may contribute to
genital aging, with an apparent greater involvement in vaginal signs of atrophy.
Women with thyroid ADs reported more severe VVA symptoms, but specific
symptomatological clusters should be investigated in larger samples. Our data
support the need to explore further the role of thyroid disorders in VVA.
Autor/es:Cucinella, Laura (a) Barbagallo, Federica (b)
institución:(a) Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy. (b) Research Center for Reproductive Medicine, Gynecological Endocrinology and Menopause, IRCCS San Matteo Foundation, Pavia, Italy.
Glucokinase Regulatory Protein as a Putative Target for Gestational Diabetes Mellitus and Related Complications: Evidence From the Mendelian Randomization Study.
Glucokinase Regulatory Protein as a Putative Target for Gestational Diabetes Mellitus and Related Complications: Evidence From the Mendelian Randomization Study.
Fuente:Journal of Diabetes
Extracto:
This study provided novel
evidence that circulating GCKR levels are causally implicated in GDM and related
complications, suggesting that it may be a promising target for treatment.
Claves:Mendelian randomization, gestational diabetes mellitus, glucokinase regulatory protein
Cita:J Diabetes 2025 Feb; 17 (2) : e70056.
Autor/es:Mao, Weian (a) Wang, Guiquan (b)
institución:(a) Reproductive Medicine Center, Zhongshan Hospital, Fudan University, Shanghai, China. (b) Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Prevalence and risk factors of gestational diabetes mellitus among pregnant women in northern Vietnam: a cross-sectional study.
Prevalence and risk factors of gestational diabetes mellitus among pregnant women in northern Vietnam: a cross-sectional study.
Fuente:Global Health Action
Extracto:
More than one-fourth of pregnant women in Thai Binh,
Vietnam, may have GDM. Advanced maternal age, high pregestational body mass
index, family history of diabetes, and previous GDM were associated with
increased risk of GDM. Additionally, fertility treatment appears to be strongly
associated with an increased risk of GDM.
Cita:Glob Health Action 2025 Dec; 18 (1) : 2460339.
Autor/es:Le, Hieu Minh (a) Nguyen, Thi Ai (b)
institución:(a) Department of Internal Medicine, Thai Binh University of Medicine and Pharmacy, Thai Binh, Vietnam. (b) Department of Internal Medicine, Hanoi Medical University, Hanoi, Vietnam.
Conflicto:No potential conflict of interest was reported by the author(s).
Associations of maternal PM2.5 exposure with preterm birth and miscarriage in women undergoing in vitro fertilization
Associations of maternal PM2.5 exposure with preterm birth and miscarriage in women undergoing in vitro fertilization
Fuente:Frontiers in Endocrinology
Tipo de trabajo:Estudio de cohortes
Extracto:
Excessive PM2.5 exposure after biochemical pregnancy or clinical
pregnancy was associated with increased risks of preterm birth and miscarriage
among women who underwent ART.
Claves:PM2.5 exposure, in vitro fertilization, miscarriage, particulate matter, preterm birth
institución:(a) Centre for Assisted Reproduction, Shanghai Key Laboratory of Maternal Fetal Medicine, Shanghai Institute of Maternal-Fetal Medicine and Gynecologic Oncology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, China. (b) Centre for Assisted Reproduction, Shanghai Key Laboratory of Maternal Fetal Medicine, Shanghai Institute of Maternal-Fetal Medicine and Gynecologic Oncology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Effect of Precise Pulmonary Rehabilitation Nursing Intervention Combined With Simultaneous Inhalation Therapy and Noninvasive Ventilation for Chronic Obstructive Pulmonary Disease Patients With Chronic Hypercapnic Respiratory Failure.
Effect of Precise Pulmonary Rehabilitation Nursing Intervention Combined With Simultaneous Inhalation Therapy and Noninvasive Ventilation for Chronic Obstructive Pulmonary Disease Patients With Chronic Hypercapnic Respiratory Failure.
Fuente:The Clinical Respiratory Journal
Extracto:
The complex COPD patients with chronic hypercapnic respiratory failure may confer
more gains from precise pulmonary rehabilitation nursing intervention combined
with simultaneous inhalation therapy and noninvasive ventilation.
institución:(a) Department of Endocrinology, Chinese People's Liberation Army Western Theater Command General Hospital, Chengdu, Sichuan, China. (b) Department of Respiratory and Critical Care Medicine, Chinese People's Liberation Army Western Theater Command General Hospital, Chengdu, Sichuan, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Experimental and clinical transplantation official journal of the Middle East Society for Organ Transplantation
Selección SIIC: 13 Febrero, 2025
Experimental and clinical transplantation official journal of the Middle East Society for Organ Transplantation
Prolonged Hospital Stay Predicts Worse Outcomes After Pancreas Transplantation: An Analysis of the SRTR Database.
Prolonged Hospital Stay Predicts Worse Outcomes After Pancreas Transplantation: An Analysis of the SRTR Database.
Fuente:Experimental and Clinical Transplantation Official Journal of The Middle East Society For Organ Transplantation
Extracto:
Prolonged length of hospital stay was significantly related to reduced graft and
patient survival rates after pancreas transplant. Optimizing factors that may
lead to prolonged length of stay and providing targeted adjuvant therapy can
potentially mitigate associated adverse effects and reduce postoperative
expenses.
Metabolomics Official journal of the Metabolomic Society
Selección SIIC: 13 Febrero, 2025
Metabolomics Official journal of the Metabolomic Society
Unveiling the metabolomic profile of growth hormone deficiency children using NMR spectroscopy.
Unveiling the metabolomic profile of growth hormone deficiency children using NMR spectroscopy.
Fuente:Metabolomics Official Journal of The Metabolomic Society
Extracto:
This study provides evidence that metabolome plays a pivotal role in
GHD, but large-scale multicenter studies are warranted to validate the results.
Autor/es:Aggelaki, Eftychia A (a) Giannakopoulos, Aristeidis (b)
institución:(a) Department of Pharmacy, School of Health Sciences, University of Patras, 26504, Rio, Greece. (b) Division of Endocrinology Department of Pediatrics, Medical School, University of Patras, 26504, Rio, Greece.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
