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The increasing number of Open Access articles widens the reading offer
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consult a profuse amount of documents that will feed
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SIIC created, produced and handles the AFT software that deciphers
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While most of the selected texts belong to original articles,
reviews, and guidelines, readers will also find commentaries,
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Microscopic testicular sperm extraction in 46, XY differences in sex development caused by 5-alpha reductase type 2 deficiency.
Microscopic testicular sperm extraction in 46, XY differences in sex development caused by 5-alpha reductase type 2 deficiency.
Fuente:Archives of Endocrinology and Metabolism
Extracto:
Early orchidopexy and penile and
urethral corrections should be considered key strategies to preserve the
fertility potential of 5ARD2 patients.
Cita:Arch Endocrinol Metab 2025 Feb 13; 69 (1) : e240223.
Autor/es:Cardoso, Joao Paulo Greco (a) Mendonça, Berenice Bilharinho (b)
institución:(a) Divisão de Urologia, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brasil. (b) Disciplina de Endocrinologia, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brasil.
Exercise and eating behaviors among Austrian transgender and gender-diverse adolescents.
Exercise and eating behaviors among Austrian transgender and gender-diverse adolescents.
Fuente:European Journal of Pediatrics
Extracto:
The results of
this study point towards the complexity of healthcare needs in the TGD adolescent
population. The interconnectedness of mental health and exercise behavior is well
described. However, qualitative work is needed to understand the specific
relationship between gender expression, body image, eating and exercise
behaviors, as well as social inclusion. WHAT IS KNOWN: • Transgender and
gender-diverse (TGD) adolescents are at an increased risk for obesity. The causes
for this are most likely complex, and remain poorly understood. • Survey studies
in the United States and New Zealand have reported reduced levels of physical
activity in the TGD population. However, data is scarce, particularly regarding
adolescents. WHAT IS NEW: • This prospective, national survey study is the first
to demonstrate reduced levels of self-reported physical activity in a cohort of
central European TGD adolescents.
Claves:Adolescence, Exercise, Gender diversity, Gendered embodiment, Obesity, Social inclusion
Cita:Eur J Pediatr 2025 Feb 13; 184 (3) : 197.
Autor/es:Knaus, Sarah (a) Teutsch, Friedrich (b)
institución:(a) Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria. sarah.knaus@meduniwien.ac.at. (b) Austrian National Public Health Institute (Gesundheit Österreich GmbH), Vienna, Austria.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Associations Between Serum IL-17A, Renal Function and Diabetic Retinopathy in Type 2 Diabetes Mellitus: Evidence From a Chinese Han Population.
Associations Between Serum IL-17A, Renal Function and Diabetic Retinopathy in Type 2 Diabetes Mellitus: Evidence From a Chinese Han Population.
Fuente:Endocrinology, Diabetes & Metabolism
Extracto:
Serum IL-17A level is associated with renal function
decline and diabetic retinopathy in patients with type 2 diabetes in a Chinese
Han population. Our results suggested that IL-17A may be a potential biomarker of
DKD and DR.
institución:(a) Department of Geriatrics, The Second Affiliated Hospital of Guizhou University of TCM, Guiyang, Guizhou, China. (b) Division of Nephrology, Affiliated Hospital of Chengde Medical College, Chengde, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Correlation Between Triglyceride-Glucose Index and Microvascular Complications in Patients With Early- Onset of Type 2 Diabetes Mellitus.
Correlation Between Triglyceride-Glucose Index and Microvascular Complications in Patients With Early- Onset of Type 2 Diabetes Mellitus.
Fuente:Endocrinology, Diabetes & Metabolism
Extracto:
In patients with
early-onset T2DM, the TyG index could be used to evaluate the risk of
microvascular complications, with elevated TyG levels potentially indicating high
risk of insulin- resistance related renal injury.
Claves:diabetic nephropathy, early‐onset diabetes mellitus, triglyceride–glucose index
institución:(a) The Tianjin Fourth Central Hospital of Tianjin Medical University, Tianjin, China. (b) Department of Cardiology, Tianjin Union Medical Center, Nankai University Affiliated Hospital, Tianjin, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Identification of early predictors and model for bacterial infection in diabetic ketoacidosis patients: A retrospective study.
Identification of early predictors and model for bacterial infection in diabetic ketoacidosis patients: A retrospective study.
Fuente:Plos One
Extracto:
CRP and cortisol are early indicators of bacterial infection in DKA
patients. Furthermore, based on their combination, the regression diagnostic
model exhibits enhanced diagnostic performance.
Cita:PLoS One 2025; 20 (2) : e0318261.
Autor/es:Hao, Yaping (a) Yang, Lei (b)
institución:(a) Department of Endocrinology, Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong, China. (b) Department of Endocrinology, Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
STMiner: Gene-centric spatial transcriptomics for deciphering tumor tissues.
STMiner: Gene-centric spatial transcriptomics for deciphering tumor tissues.
Fuente:Cell Genomics
Extracto:
The core concept of directly analyzing overall gene
expression patterns also allows for a broader application beyond spatial
transcriptomics, positioning STMiner for continuous expansion as spatial omics
technologies evolve.
institución:(a) School of Automation Science and Engineering, Faculty of Electronic and Information Engineering, Xi'an Jiaotong University, Xi'an, China; MOE Key Lab for Intelligent Networks & Networks Security, Faculty of Electronic and Information Engineering, Xi'an Jiaotong University, Xi'an, China. (b) School of Automation Science and Engineering, Faculty of Electronic and Information Engineering, Xi'an Jiaotong University, Xi'an, China; MOE Key Lab for Intelligent Networks & Networks Security, Faculty of Electronic and Information Engineering, Xi'an Jiaotong University, Xi'an, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Comprehensive exploration of programmed cell death landscape in lung adenocarcinoma combining multi-omic analysis and experimental verification.
Comprehensive exploration of programmed cell death landscape in lung adenocarcinoma combining multi-omic analysis and experimental verification.
Fuente:Scientific Reports
Extracto:
Given all the above, a novel CDI gene
signature was indicated to predict the prognosis and exploit precision
therapeutic strategies of LUAD patients.
Claves:Lung adenocarcinoma, Precision treatment, Programmed cell death, Unfold protein response
Cita:Sci Rep 2025 Feb 13; 15 (1) : 5364.
Autor/es:Yu, Peng (a) Xiao, Leyang (b)
institución:(a) Department of Endocrinology and Metabolism, The Second Affiliated Hospital of Nanchang University, Nanchang, China. (b) Department of Endocrinology and Metabolism, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Clinical characteristics and unique presentations of immune checkpoint inhibitor induced type 1 diabetes in Chinese patients from a single institution.
Clinical characteristics and unique presentations of immune checkpoint inhibitor induced type 1 diabetes in Chinese patients from a single institution.
Fuente:Scientific Reports
Extracto:
Furthermore, the observed
greater glucose variability in ICI-T1D emphasizes the critical importance of
diabetes education and personalized insulin regimen.
institución:(a) Department of Endocrinology and Metabolism, Peking University People's Hospital, No. 11, Xizhimen Nan Da Jie, Xicheng District, Beijing, 100044, People's Republic of China. (b) Department of Endocrinology and Metabolism, Peking University People's Hospital, No. 11, Xizhimen Nan Da Jie, Xicheng District, Beijing, 100044, People's Republic of China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Metabolic biomarkers of clinical outcomes in severe mental illness (METPSY): protocol for a prospective observational study in the Hub for metabolic psychiatry.
Metabolic biomarkers of clinical outcomes in severe mental illness (METPSY): protocol for a prospective observational study in the Hub for metabolic psychiatry.
Autor/es:Rakshasa-Loots, Arish Mudra (a) Steyn, Christina (b)
institución:(a) Division of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK. (b) Division of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
Conflicto:Declarations. Ethics approval and consent to participate: This study will be carried out in accordance with internationally recognised standards for ethical research and the Declaration of Helsinki. All participants will provide written informed consent to take part in the study. This study has received ethical approval from the NHS North of Scotland Research Ethics Committee (1) (REC reference: 24/NS/0138). Consent...
for publication: Not applicable. Competing interests: RKS has received consulting fees from Astra Zeneca and Alnylam, and speaking fees from Novo Nordisk, Eli Lilly, and Amryt, all relating to severe insulin resistance and/or lipodystrophy. SML has been paid to give an educational talk on cognition in schizophrenia to employees of Kynexis. SLL is a cofounder of Dynamic Therapeutics.
Elevated plasma soluble lectin-like oxidised low-density lipoprotein receptor 1 as an independent prognostic biomarker in sepsis.
Elevated plasma soluble lectin-like oxidised low-density lipoprotein receptor 1 as an independent prognostic biomarker in sepsis.
Fuente:Lipids in Health and Disease
Extracto:
Plasma levels of sLOX-1 are elevated in patients with SIRS or sepsis and are
significantly higher in non-survivors. Of note, they do not correlate with
classical inflammatory markers, suggesting that sLOX-1 may function as an
independent prognostic biomarker for predicting poor outcomes in patients with
SIRS or sepsis.
Autor/es:Mester, Patricia (a) Birner, Charlotte (b)
institución:(a) Department of Internal Medicine I, Gastroenterology, Hepatology, Endocrinology, Rheumatology, and Infectious Diseases, University Hospital Regensburg, 93053, Regensburg, Germany. (b) Department of Internal Medicine I, Gastroenterology, Hepatology, Endocrinology, Rheumatology, and Infectious Diseases, University Hospital Regensburg, 93053, Regensburg, Germany.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Relationship between serum carotenoids and osteoarthritis or degenerative arthritis: A cross-sectional study using the National Health and Nutrition Examination Survey.
Relationship between serum carotenoids and osteoarthritis or degenerative arthritis: A cross-sectional study using the National Health and Nutrition Examination Survey.
Fuente:Nutrition Journal
Extracto:
In the American
population, trans-lycopene rather than other types of carotenoids may exhibit a
significantly negative correlation with OA, displaying a nonlinear pattern with a
threshold point of approximately 19.49 µg/dl. This relationship may become more
pronounced with increasing age.
institución:(a) Hongqiao International Medical Research Institute of Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China. (b) Department of Clinical Laboratory, Nanjing Central Hospital, Nanjing, People's Republic of China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Clonal hematopoiesis of indeterminate potential, health indicators, and risk of cardiovascular diseases among patients with diabetes
Clonal hematopoiesis of indeterminate potential, health indicators, and risk of cardiovascular diseases among patients with diabetes
Fuente:Cardiovascular Diabetology
Tipo de trabajo:Estudio de cohortes
Extracto:
CHIP is independently associated with
an increased risk of CVD in patients with diabetes, regardless of health
indicator levels. Diabetic patients with CHIP but ideal health indicators still
exhibited higher CVD risk compared with diabetic patients without CHIP.
Claves:Cardiovascular diseases, Clonal hematopoiesis of indeterminate potential, Diabetes, Health indicator
Cita:Cardiovasc Diabetol 2025 Feb 13; 24 (1) : 72.
Autor/es:Sun, Ying (a) Yu, Yuefeng (b)
institución:(a) Department of Endocrinology and Metabolism, Institute of Endocrinology and Metabolism, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China. (b) Department of Endocrinology and Metabolism, Institute of Endocrinology and Metabolism, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Correlation of anti-oxidant and pro-oxidant enzymes with insulin resistance in diabetic nephropathy.
Correlation of anti-oxidant and pro-oxidant enzymes with insulin resistance in diabetic nephropathy.
Fuente:Jpma. The Journal of The Pakistan Medical Association
Extracto:
Type 2 diabetes and diabetic nephropathy induced
changes in the levels of superoxide dismutase 3, glutathione S-transferase and
nicotinamide adenine dinucleotide phosphate oxidase. Low levels of superoxide
dismutase 3 in type 2 diabetes correlated with insulin resistance, suggesting the
need for anti-oxidant replacement therapy as part of diabetes control measures to
prevent diabetic nephropathy.
institución:(a) Department of Medical Laboratory Sciences, King Abdulaziz University, Jeddah. (b) Department of Medical Laboratory Sciences, King Abdulaziz University, Jeddah.
institución:(a) Department of Medicine, Hearts International Hospital, Rawalpindi, Pakistan. (b) Department of Endocrinology, Hearts International Hospital, Rawalpindi, Pakistan.
Immunotherapy in Type 1 Diabetes: Emerging Therapies and Future Directions.
Immunotherapy in Type 1 Diabetes: Emerging Therapies and Future Directions.
Fuente:Jpma. The Journal of The Pakistan Medical Association
Extracto:
As this
therapeutic landscape evolves, further research is critical to optimizing these
strategies and moving closer to a potential cure for T1D.
institución:(a) Department of Endocrinology, Indraprastha Apollo Hospitals, New Delhi, India. (b) Department of Endocrinology, Indraprastha Apollo Hospitals, New Delhi, India.
Fuente:Jpma. The Journal of The Pakistan Medical Association
Extracto:
The
socebo construct needs to be studied objectively, in both acute and chronic
disease, including diabetes and obesity.
Claves:Chronic disease, nocebo, placebo, psychosocial aspects, social pharmacology
Cita:J Pak Med Assoc 2025 Feb; 75 (2) : 33-333.
Autor/es:Kalra, Sanjay (a) Verma, Madhur (b)
institución:(a) Department of Endocrinology, Bharti Hospital, Karnal, India; University Centre for Research & Development, Chandigarh University, Mohali, India. (b) Department of Community/Family Medicine, All India Institute of Medical Sciences, Bathinda, India.
Fuente:Jpma. The Journal of The Pakistan Medical Association
Extracto:
We discuss these parameters in relation to health and explore their
relevance to disease prevention and management.
Claves:Chronic disease, culinary medicine, diet, nutrition, social aspects
Cita:J Pak Med Assoc 2025 Feb; 75 (2) : 334-337.
Autor/es:Kalra, Sanjay (a) Kalra, Bharti (b)
institución:(a) Department of Endocrinology, Bharti Hospital, Karnal, India; University Center for Research & Development, Chandigarh University, Mohali, India. (b) Department of Obstetrics and Gynaecology, Bharti Hospital, Karnal, India.
Fuente:Jpma. The Journal of The Pakistan Medical Association
Tipo de trabajo:Revisión
Extracto:
This article reviews
the pathophysiological underpinnings of depression in CKD, explores the impact of
dialysis on depressive symptoms, and evaluates whether depression can be
considered a "dialyzable" entity.
institución:(a) Department of Nephrology, VMMC & Safdarjung Hospital, New Delhi, India. (b) Department of Endocrinology, Bharti Hospital, Karnal, India; University Center for Research & Development, Chandigarh University, Mohali, India.
Extracto:
UCF cooking had significant
impact on ocular health, notably on eye symptoms, cataracts, and visual
impairments. UCF exposure presented demographic inequalities in cataract
prevalence, while eye symptoms can serve as a reliable self-assessment of UCF
exposure.
Claves:cataracts, health inequalities, ocular symptoms, unclean cooking fuel, visual impairments
Cita:Front Public Health 2024; 12 : 1434611.
Autor/es:Chen, Shi-Hang (a) Tang, Yuan (b)
institución:(a) National Clinical Research Center for Metabolic Diseases, Metabolic Syndrome Research Center, Key Laboratory of Diabetes Immunology, Ministry of Education, and Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, Changsha, China. (b) National Clinical Research Center for Metabolic Diseases, Metabolic Syndrome Research Center, Key Laboratory of Diabetes Immunology, Ministry of Education, and Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, Changsha, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Positive Islet Cell Cytoplasmic Antibody and Long-Term Use of Lipid-Lowering Agents Are Positively Correlated With Peripheral Atherosclerosis in Patients With Autoimmune Diabetes: A Cross-Sectional Study.
Positive Islet Cell Cytoplasmic Antibody and Long-Term Use of Lipid-Lowering Agents Are Positively Correlated With Peripheral Atherosclerosis in Patients With Autoimmune Diabetes: A Cross-Sectional Study.
Fuente:Journal of Diabetes Research
Extracto:
The association between
long-term use of lipid-lowering agents and atherosclerosis suggests the need for
early screening and intervention for dyslipidemia in patients with autoimmune
diabetes.
institución:(a) Department of Endocrinology, Key Laboratory of Endocrinology, Ministry of Health, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China. (b) Department of Endocrinology, Key Laboratory of Endocrinology, Ministry of Health, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación