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Sociedad Iberoamericana de Información Científica (SIIC) selects
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Bases.
The increasing number of Open Access articles widens the reading offer
but, also, such myriad complicates the readers search of fundamental
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consult a profuse amount of documents that will feed
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SIIC created, produced and handles the AFT software that deciphers
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dates, source definition, query limitations, summary in Spanish,
etc.
While most of the selected texts belong to original articles,
reviews, and guidelines, readers will also find commentaries,
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that may lead to discussions or clarifications.
CO2 and aerosol concentration during manual and mechanical chest compression while cardiopulmonary resuscitation.
CO2 and aerosol concentration during manual and mechanical chest compression while cardiopulmonary resuscitation.
Fuente:Medicine
Extracto:
These findings highlight the potential benefits of
employing mechanical chest compressions to mitigate staff-to-staff infections in
small, confined spaces during aerosol-transmitted diseases.
Cita:Medicine (Baltimore) 2025 Feb 14; 104 (7) : e41528.
Autor/es:Heymer, Johannes (a) Dengler, Florian (b)
institución:(a) Department of Interdisciplinary Emergency and Intensive Care Medicine, Klinikum Stuttgart, Stuttgart, Germany. (b) Department of Interdisciplinary Emergency and Intensive Care Medicine, Klinikum Stuttgart, Stuttgart, Germany.
Conflicto:The authors have no funding and conflicts of interest to disclose.
Duodenal fluid analysis is an excellent differential diagnosis method of diseases with enterohepatic circulation disturbance.
Duodenal fluid analysis is an excellent differential diagnosis method of diseases with enterohepatic circulation disturbance.
Fuente:Medicine
Extracto:
This study also indicates that the test is a useful diagnostic
method with high accuracy for other diseases with enterohepatic circulation
disturbance.
Cita:Medicine (Baltimore) 2025 Feb 14; 104 (7) : e41469.
Autor/es:Dong, Chen (a) Liu, Sheng-Xuan (b)
institución:(a) Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China. (b) Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Conflicto:The authors have no funding and conflicts of interest to disclose.
Feasibility and acceptability of a personalised primary prevention strategy for women and men at high risk of breast and prostate cancer
Feasibility and acceptability of a personalised primary prevention strategy for women and men at high risk of breast and prostate cancer
Fuente:Bmj Open
Tipo de trabajo:Estudio aleatorizado y controlado
Extracto:
TRIAL REGISTRATION NUMBER:
The protocol for this study was registered with the International Clinical Trials
Registry (ISRCTN15749766) https://doi.org/10.1186/ISRCTN15749766).
institución:(a) Oncology Axis, Centre de recherche du CHU Québec-Université Laval, Quebec, Québec, Canada. (b) Oncology Axis, Centre de recherche du CHU Québec-Université Laval, Quebec, Québec, Canada.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Extracto:
A significant nonlinear, J-shaped association was noted between TSH
level and frailty. TSH levels within the upper half (2.7-4.8mIU/L) of reference
range was noted to significantly higher risk of frailty; by contrast, those in
the lower half (0.6-1.5 mIU/L) had a lower risk of frailty, though not
significantly so. TRAIL REGISTRATION: This systematic review was registered with
PROSPERO (registration number: CRD42022299214).
Claves:Frailty, TSH, Thyroid hormone
Cita:BMC Geriatr 2025 Feb 17; 25 (1) : 104.
Autor/es:Chia, Wen-Chun (a) Chen, Yang-Ching (b)
institución:(a) Department of Family Medicine, Taipei Medical University Hospital, Taipei, Taiwan. (b) Department of Family Medicine, Wan Fang Hospital, Taipei Medical University, Taipei, 116, Taiwan.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Preparedness for the future in patients with relapsed or refractory hematopoietic malignancies in the treatment process: a qualitative study.
Preparedness for the future in patients with relapsed or refractory hematopoietic malignancies in the treatment process: a qualitative study.
Fuente:Annals of Palliative Medicine
Extracto:
Patients with hematopoietic malignancies who are undergoing
treatment may be motivated by a variety of different factors to continue with
treatment. Discussing patients' goals and wishes with respect to treatment is
critically important to ensure that such treatment is aligned with patients'
preferences.
Claves:Hematopoietic malignancy, patient goals, patient preference, preparedness for the future, relapsed or refractory hematopoietic malignancy (R/R hematopoietic malignancy)
Cita:Ann Palliat Med 2025 Jan; 14 (1) : 43-56.
Autor/es:Akashi, Kazuko (a) Imai, Yoshie (b)
institución:(a) Department of Nursing, Fuchu Hospital, Osaka, Japan; Graduate School of Biomedical Sciences, The University of Tokushima, Tokushima, Japan. (b) Faculty of Biomedical Sciences, Department of Cancer Nursing, Graduate School, The University of Tokushima, Tokushima, Japan.
Automated Process for Monitoring of Amiodarone Treatment: Development and Evaluation.
Automated Process for Monitoring of Amiodarone Treatment: Development and Evaluation.
Fuente:Journal of Medical Internet Research
Extracto:
An automated process, using a
software robot and a diagnostic classification algorithm, is a technically and
medically reliable alternative for amiodarone follow-up. It may reduce manual
labor, decrease the frequency of laboratory testing, and improve the detection of
side effects, thereby reducing costs and enhancing patient value.
Autor/es:Johansson, Birgitta I (a) Landahl, Jonas (b)
institución:(a) Department of Molecular and Clinical Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. (b) Department of Medicine, Geriatrics and Emergency Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden.
Extracto:
LESSONS: The scarcity of P-EHE complicates its diagnosis and treatment,
underscoring the importance of ongoing research to enhance our understanding of
this condition.
Cita:Medicine (Baltimore) 2024 Dec 27; 103 (52) : e40959.
Autor/es:Xuan, Rong (a) Cui, Zhengsen (b)
institución:(a) Department of Endocrinology and Metabolism, Hangzhou Third People's Hospital, Hangzhou, Zhejiang Province, China. (b) Department of Geriatric Medicine Department, The First Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang province, China.
Conflicto:The authors have no funding and conflicts of interest to disclose.
Graves ophthalmopathy a neglected comorbidity of graves' disease; a detailed investigation and management of sixty-eight patients in a tertiary healthcare center.
Graves ophthalmopathy a neglected comorbidity of graves' disease; a detailed investigation and management of sixty-eight patients in a tertiary healthcare center.
Fuente:Bmc Endocrine Disorders
Tipo de trabajo:Guía
Extracto:
Baseline serum fT3, fT4 and TRAbs in patients with Graves' Disease
levels may be the prognostic factors in the evaluation of affecting intraocular
structure, especially Retinal Nerve Fiber Layer, in patients with GO.
institución:(a) Faculty of Medicine, Division of Endocrinology, Cukurova University, Adana, 01330, Turkey. tugrulgamze@hotmail.com. (b) Faculty of Medicine, Division of Ophthalmology, Cukurova University, Adana, Turkey.
Conflicto:Declarations. Conflict of interest: In our study there is no conflict of interests. Ethical approval: Ethical approval document was obtained from Cukurova University ethical committe. Informed consent: We obtained informed consent of all patients. Consent to Publish: Not applicable. Clinical trial number: Not applicable.
Altered association between cortisol and adrenocorticotropic hormone levels in the early stage of type 2 diabetic ketoacidosis.
Altered association between cortisol and adrenocorticotropic hormone levels in the early stage of type 2 diabetic ketoacidosis.
Fuente:Frontiers in Endocrinology
Extracto:
In the early stage of DKA, a phenomenon of altered association
between cortisol-ACTH occurs and is especially prominent in DKA patients with
infection. This altered association between cortisol-ACTH disappears after DKA
correction, and the severity of DKA is an independent influencing factor on the
cortisol level in early-stage DKA.
institución:(a) Department of Endocrinology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, China. (b) Department of Endocrinology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, China.
Conflicto:The authors declare that none the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Cortisol Circadian Rhythm and Sarcopenia in Patients With Type 2 Diabetes: A Cross-Sectional Study.
Cortisol Circadian Rhythm and Sarcopenia in Patients With Type 2 Diabetes: A Cross-Sectional Study.
Fuente:Journal of Cachexia, Sarcopenia and Muscle
Extracto:
The cortisol circadian rhythm is associated with
sarcopenia in patients with T2DM. Patients with higher levels of nighttime
cortisol, rather than morning or afternoon cortisol, have a higher risk of
sarcopenia. This result offers a new strategy for the further research of
sarcopenia.
institución:(a) Department of Endocrinology, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, China. (b) Department of Clinical Nutrition, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Diabetes mellitus, metformin's target gene AMPK, and inflammatory bowel disease: A Mendelian randomization study.
Diabetes mellitus, metformin's target gene AMPK, and inflammatory bowel disease: A Mendelian randomization study.
Fuente:Medicine
Extracto:
Furthermore, our
findings revealed that the metformin's target gene AMPK had no significant effect
on the onset of IBD.
Cita:Medicine (Baltimore) 2025 Feb 14; 104 (7) : e41532.
Autor/es:Wu, Wei (a) Tong, Huomu (b)
institución:(a) Department of Geriatrics, Chun'an First People's Hospital (Chun'an Branch of Zhejiang Provincial People's Hospital), Hangzhou, Zhejiang Province, China. (b) Department of Endocrinology, Chun'an First People's Hospital (Chun'an Branch of Zhejiang Provincial People's Hospital), Hangzhou, Zhejiang Province, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Effect of intensive nutrition training, education and support versus standard therapy in reducing the need for insulin therapy in gestational diabetes (INTENSE-GDM): a protocol for a randomised controlled single-centre trial in Denmark.
Effect of intensive nutrition training, education and support versus standard therapy in reducing the need for insulin therapy in gestational diabetes (INTENSE-GDM): a protocol for a randomised controlled single-centre trial in Denmark.
Fuente:Bmj Open
Tipo de trabajo:Revisión
Extracto:
TRIAL REGISTRATION NUMBER: NCT06127823.
Claves:DIABETES & ENDOCRINOLOGY, Diabetes in pregnancy, Health economics, NUTRITION & DIETETICS, OBSTETRICS
Cita:BMJ Open 2025 Feb 17; 15 (2) : e089231.
Autor/es:Ewers, Bettina (a) Blond, Martin B (b)
institución:(a) Department of Diabetes Care, Steno Diabetes Center Copenhagen, Herlev, Capital Region of Denmark, Denmark bettina.ewers@regionh.dk. (b) Department of Clinical and Translational Research, Copenhagen University Hospital - Steno Diabetes Center Copenhagen, Herlev, Denmark.
Conflicto:Competing interests: Steno Diabetes Center Copenhagen (SDCC) is a hospital providing health services within the public healthcare system. The research project and SDCC are partially funded by the Novo Nordisk Foundation through unrestricted grants. The Novo Nordisk Foundation has no financial interest in the study and has no influence on the (1) study design; (2) collection, analysis and interpretation of...
data; (3) writing of the study report and publication and (4) decision to submit the paper for publication. The investigators have no financial, personal or professional associations that could be perceived as influencing the study. They will not benefit economically from conducting this study and have no competing interest to declare.
Global, regional, and national burden of chronic kidney disease and its underlying etiologies from 1990 to 2021: a systematic analysis for the Global Burden of Disease Study 2021.
Global, regional, and national burden of chronic kidney disease and its underlying etiologies from 1990 to 2021: a systematic analysis for the Global Burden of Disease Study 2021.
Fuente:Bmc Public Health
Extracto:
The study unveiled the uneven global distribution of the burden of
CKD and its attributable causes. From 1990 to 2021, an increase in the burden of
incidence, mortality, and DALYs due to CKD was observed. Population growth and
aging will contribute to a further increase in the burden of CKD. Healthcare
providers should develop health policies, and optimize the allocation of medical
resources, based on age, sex, region, and disease type.
Claves:Age and gender distribution, Chronic kidney disease, Etiology, Global burden of disease study, Time trend
Cita:BMC Public Health 2025 Feb 17; 25 (1) : 636.
Autor/es:Deng, Ling (a) Guo, Shujin (b)
institución:(a) Department of Health Management and Institute of Health Management, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China. (b) Department of Health Management and Institute of Health Management, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Three-protein signature is associated with baseline and persistently elevated or recurrent depressive symptoms in individuals with recent-onset diabetes.
Three-protein signature is associated with baseline and persistently elevated or recurrent depressive symptoms in individuals with recent-onset diabetes.
Fuente:Bmj Open Diabetes Research & Care
Extracto:
However, results were not significant after adjustment for multiple testing.In
conclusion, the three-protein signature identified may provide insights into
mechanisms underlying depressive symptoms in diabetes and might open new
therapeutic avenues.The trial registration number of the study is NCT01055093.
Cita:BMJ Open Diabetes Res Care 2025 Feb 18; 13 (1)
Autor/es:Spagnuolo, Maria C (a) Gottmann, Pascal (b)
institución:(a) Institute for Clinical Diabetology, German Diabetes Center (DDZ), Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany. (b) German Center for Diabetes Research (DZD), München, Germany.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Alterations of hepatic lipid content following COVID-19 in persons with type 2 diabetes.
Alterations of hepatic lipid content following COVID-19 in persons with type 2 diabetes.
Fuente:Bmj Open Diabetes Research & Care
Extracto:
History of COVID-19 in persons with type 2 diabetes is associated
with higher HL-PDFF after 1 year following recovery from infection. TRIAL
REGISTRATION NUMBER: NCT01055093.
Claves:COVID-19, Diabetes Mellitus, Type 2
Cita:BMJ Open Diabetes Res Care 2025 Feb 18; 13 (1)
institución:(a) Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany. (b) German Center for Diabetes Research (DZD), Partner Düsseldorf, Neuherberg, Germany.
Conflicto:Competing interests: MR received fees consulting, lecturing or serving on advisory boards from AstraZeneca, Boehringer Ingelheim, Echosens, Eli Lilly, Merck-MSD, Madrigal, Novo Nordisk, and Target RWE and has performed investigator-initiated research with support from Boehringer Ingelheim, Novo Nordisk and Nutricia/Danone to DDZ. MR's research is supported by grants from the German Research Foundation (DFG; RTG/GRK 2576), the European Community (HORIZON-HLTH-2022-STAYHLTH-02-01:...
panel A) to the INTERCEPT-T2D consortium, BMG, MKW, BMBF and the Schmutzler-Stiftung.
Assessing the effectiveness of continuous glucose monitoring compared with conventional monitoring in enhancing surgical outcomes for patients with diabetes
Assessing the effectiveness of continuous glucose monitoring compared with conventional monitoring in enhancing surgical outcomes for patients with diabetes
institución:(a) Department of Anesthesiology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China. (b) Department of Anesthesiology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Iron-Deficiency Anemia Elevates Risk of Diabetic Kidney Disease in Type 2 Diabetes Mellitus.
Iron-Deficiency Anemia Elevates Risk of Diabetic Kidney Disease in Type 2 Diabetes Mellitus.
Fuente:Journal of Diabetes
Extracto:
IDA increases susceptibility to DKD, possibly through oxidative
stress and altered small molecule transport. However, iron supplementation does
not appear to increase the risk of DKD.
Claves:Mendelian randomization, diabetic kidney disease, iron metabolism, iron supplementation, iron‐deficiency anemia
Cita:J Diabetes 2025 Feb; 17 (2) : e70060.
Autor/es:Huang, Bin (a) Wen, Wenjie (b)
institución:(a) Department of Endocrinology, Division of Life Science and Medicine, The First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, Anhui, China. (b) Wannan Medical College, Wuhu, Anhui, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Association between physical activity and diabetes mellitus: mediation analysis involving Systemic Immune-Inflammatory Index in a cross-sectional NHANES study.
Association between physical activity and diabetes mellitus: mediation analysis involving Systemic Immune-Inflammatory Index in a cross-sectional NHANES study.
Fuente:Bmj Open
Extracto:
This study investigated the relationship among PA, SII
and DM. We provide robust evidence supporting the inverse association between PA
and DM risk while highlighting the mediating role of inflammation, as reflected
by SII. These findings contribute valuable insights to inform public health
strategies and clinical interventions aimed at reducing the global burden of DM.
Claves:DIABETES & ENDOCRINOLOGY, General diabetes, General endocrinology
Cita:BMJ Open 2025 Feb 19; 15 (2) : e082996.
Autor/es:Chen, Yongze (a) Huang, Ruixian (b)
institución:(a) Department of Epidemiology and Medical Statistics, School of Public Health, Guangdong Medical University, Dongguan, Guangdong, China. (b) Department of Gastroenterology, Affiliated Hospital of Guangdong Medical University, Guangdong Medical University, Zhanjiang, Guangdong, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Climate footprint of industry-sponsored in-human clinical trials: life cycle assessments of clinical trials spanning multiple phases and disease areas.
Climate footprint of industry-sponsored in-human clinical trials: life cycle assessments of clinical trials spanning multiple phases and disease areas.
Fuente:Bmj Open
Tipo de trabajo:Estudio clínico
Extracto:
Based on our LCAs of
seven clinical trials spanning all four phases of development and multiple
disease areas, there are five activities that drive no less than 79% of the
average clinical trial's GHG footprint. These are drug product manufacture,
packaging, and distribution; patient travel; on-site monitoring visit travel; the
collection, transport and processing of laboratory samples; and sponsor staff
commuting between their homes and the office. Understanding the activities that
drive GHG emissions in clinical trials can both guide trial designers in avoiding
or minimising reliance on these activities when designing new trials and guide
trial sponsors in taking targeted actions to reduce GHG emissions from these
activities where their use cannot be avoided. TRIAL REGISTRATION NUMBER:
TMC114FD1HTX1002 (ClinicalTrials.gov: NCT04208061), 77242113PSO2001
(ClinicalTrials.gov: NCT05364554), 42756493BLC2002 (ClinicalTrials.gov:
NCT03473743), 54767414MMY3012 (ClinicalTrials.gov: NCT03277105), VAC18193RSV3006
(ClinicalTrials.gov: NCT05070546), R092670PSY3016 (ClinicalTrials.gov:
NCT04072575) and 28431754DIA4032 (ClinicalTrials.gov: NCT04288778).
Autor/es:LaRoche, Jason Keith (a) Lanier, Jason (b)
institución:(a) Innovative Health, Johnson & Johnson Innovative Medicine, Delft, Zuid Holland, The Netherlands jlaroche@its.jnj.com. (b) Industrial Design Engineering, Delft University of Technology, Delft, The Netherlands.
Conflicto:Competing interests: JKL is an employee of Johnson & Johnson Innovative Medicine, LLC, and a member of the faculty at Delft University of Technology. JL is an employee of Johnson & Johnson Innovative Medicine, LLC. RA is an employee of Environmental Resource Management, LLC. MC is an employee of Environmental Resource Management, LLC. TC is an employee of Environmental Resource...
Management, LLC. HW is an employee of Environmental Resource Management, LLC. AC is an employee of ICON, PLC. WDS is an employee of Johnson & Johnson Innovative Medicine, LLC. JF is a faculty member at Delft University of Technology. KR is an employee of Johnson & Johnson Innovative Medicine, LLC.
