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La Sociedad Iberoamericana de Información Científica (SIIC)
selecciona informes completos de calidad recientemente publicados en
fuentes prestigiosas del mundo indizadas por SIIC Data
Bases.
La creciente cantidad de artículos con Acceso Abierto (Open
Access) amplía la oferta de lectura pero a su vez también, entre
tanta abundancia, complica al lector en su encuentro con los estudios
fundamentales. Para facilitarlo, profesionales biomédicos de SIIC
consultan diariamente una profusa cantidad de documentos que nutrirán
Textos completos autorizados (TCA).
Las citas de la sección TCA enlazan de manera legal, autorizada y
gratuita con los textos completos (full text) publicados en
los sitios oficiales de sus respectivas fuentes.
SIIC creó, produjo y opera con exclusividad el software TCA para la
interpretación de los diversos campos documentales que integran la
estructura de un estudio: especialidad, modalidad del estudio,
fuente, fechas de publicación y selección, definición de la fuente,
limitaciones de consulta, resumen en castellano, etc.
Si bien la mayoría de los textos seleccionados corresponden a
artículos originales, revisiones y guías, los lectores también
encontrarán comentarios, entrevistas, notas periodísticas, cartas a
autores u otros textos precursores de debates o aclaratorios.
Sociedad Iberoamericana de Información Científica (SIIC) selects
complete quality-full texts which have been recently published in
renowned sources worldwide and are indexed by SIIC Data
Bases.
The increasing number of Open Access articles widens the reading offer
but, also, such myriad complicates the readers search of fundamental
articles. To facilitate this, SIIC biomedical professionals daily
consult a profuse amount of documents that will feed
Authorized Full Texts (TCA, Spanish acronym).
The citations of the AFT section link legally, authorized and free of
charge with the full texts published in the official web sites of
their corresponding sources.
SIIC created, produced and handles the AFT software that deciphers
the various documentary fields that form part of the structure of a
study: specialty, study style, source, publication and selection
dates, source definition, query limitations, summary in Spanish,
etc.
While most of the selected texts belong to original articles,
reviews, and guidelines, readers will also find commentaries,
interviews, journalistic reports, letters to authors or other texts
that may lead to discussions or clarifications.
Decentralized Clinical Trials in the Era of Real-World Evidence: A Statistical Perspective.
Decentralized Clinical Trials in the Era of Real-World Evidence: A Statistical Perspective.
Fuente:Clinical and Translational Science
Extracto:
This paper is
intended to provide statistical considerations for decentralized trials of
medical products to support regulatory decision-making.
Claves:digital healthcare technology, estimand, remote data acquisition, statistical analysis plan
Cita:Clin Transl Sci 2025 Feb; 18 (2) : e70117.
Autor/es:Chen, Jie (a) Di, Junrui (b)
institución:(a) Data Science, ECR Global, Shanghai, China. (b) Global Product Development, Pfizer Inc, Cambridge, Massachusetts, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
A social return on investment analysis of patient-reported outcome measures in value-based healthcare.
A social return on investment analysis of patient-reported outcome measures in value-based healthcare.
Fuente:Journal of Patient-reported Outcomes
Extracto:
These findings
demonstrate the complexities of implementing PROMs within a clinical context, and
careful consideration is likely needed in selecting suitable services and
tailoring the implementation of PROMs to effectively meet specific service and
patient requirements. Where PROMs yielded low or no value, the lack of
return-on-investment prompts a strategic re-evaluation regarding how PROMs are
funded, implemented, and utilized. As the first economic evaluation of PROMs in
clinical practice, this study is a novel contribution to the emergent VBHC and
PROMs evidence base. Furthermore, the findings from this study will inform
recommendations to improve PROMs delivery across Wales.
institución:(a) School of Health Sciences, Bangor University, Bangor, UK. (b) School of Health Sciences, Bangor University, Bangor, UK.
Conflicto:Declarations. Ethics approval and consent to participate: Ethical approval for this study was granted by the Wales Research Ethics Committee 5 (ref 22/WA/0044) on 22nd March 2022. Consent for publication: Not applicable. Competing interests: Adele Cahill and Gareth Roberts are employed by ABUHB and are involved in the implementation of VBHC and PROMs in Wales.
Commensal mouth bacteria are the main cause of dentoalveolar abscesses in the maxillofacial region.
Commensal mouth bacteria are the main cause of dentoalveolar abscesses in the maxillofacial region.
Fuente:Journal of Infection in Developing Countries
Extracto:
Common oral flora caused dental
abscesses. Not much antimicrobial resistance was detected among the bacterial
isolates. However, the dentists used antibiotics irresponsibly because a few
cases were identified where the bacteria were resistant to antibiotics used prior
to removal of dentoalveolar abscesses.
Building a Primary Care Research Agenda for Latino Populations in the Setting of the Latino Paradox: A Report from the 2023 Latino Primary Care Summit.
Building a Primary Care Research Agenda for Latino Populations in the Setting of the Latino Paradox: A Report from the 2023 Latino Primary Care Summit.
Fuente:Journal of The American Board of Family Medicine Jabfm
Extracto:
6)
Workforce/Academics, Representation Inequities, and Innovation (research
training, workforce diversity, and innovation approaches).
Claves:Family Medicine, Health Disparities, Health Services Needs, Hispanic or Latino, Primary Health Care, Workforce Diversity
Cita:J Am Board Fam Med 2024 Sep-Oct; 37 (5) : 948-954.
Autor/es:Marino, Miguel (a) Abraído-Lanza, Ana F (b)
institución:(a) From the Department of Family Medicine, Oregon Health & Science University, Portland, OR, USA (MM, JAL, CEVG, JH); The Columbia School of Social Work, Columbia University, Ithaca, NY (AFAL); Division of Health Promotion and Behavioral Science, San Diego State University, College of Health & Human Services School of Public Health, San Diego, CA (BA); The Next Door Inc, Portland, OR (EB); Public Health Education, The University of North Carolina, Greensboro, NC (SEE); Department of Environmental, Occupational, Geospatial Sciences, CUNY Graduate School of Public Health and Health Policy, New York, NY (KRF); Virginia Garcia Memorial Health Center, Hillsboro, Oregon (EG); Departments of Family & Community Medicine and Population Health Sciences, Long School of Medicine, University of Texas Health Science Center at San Antonio, TX (CRJ); University of Massachusetts Amherst, School of Public Health & Health Sciences, Amherst, MA (DFLC); College of Health, School of Nutrition and Public Health, Oregon State University, Corvallis, OR (CMM); Department of Medicine, Department of Epidemiology & Population Health, Albert Einstein College of Medicine, New York, NY (CJR); School of Medicine, Oregon Health & Science University, Portland, OR (MR); OCHIN, Inc. (JH). marinom@ohsu.edu. (b) From the Department of Family Medicine, Oregon Health & Science University, Portland, OR, USA (MM, JAL, CEVG, JH); The Columbia School of Social Work, Columbia University, Ithaca, NY (AFAL); Division of Health Promotion and Behavioral Science, San Diego State University, College of Health & Human Services School of Public Health, San Diego, CA (BA); The Next Door Inc, Portland, OR (EB); Public Health Education, The University of North Carolina, Greensboro, NC (SEE); Department of Environmental, Occupational, Geospatial Sciences, CUNY Graduate School of Public Health and Health Policy, New York, NY (KRF); Virginia Garcia Memorial Health Center, Hillsboro, Oregon (EG); Departments of Family & Community Medicine and Population Health Sciences, Long School of Medicine, University of Texas Health Science Center at San Antonio, TX (CRJ); University of Massachusetts Amherst, School of Public Health & Health Sciences, Amherst, MA (DFLC); College of Health, School of Nutrition and Public Health, Oregon State University, Corvallis, OR (CMM); Department of Medicine, Department of Epidemiology & Population Health, Albert Einstein College of Medicine, New York, NY (CJR); School of Medicine, Oregon Health & Science University, Portland, OR (MR); OCHIN, Inc. (JH).
Conflicto:Conflict of interest: The authors do not have any conflicts to report.
Understanding and experience of the medical forensic examination after sexual assault: protocol for a mixed methods study.
Understanding and experience of the medical forensic examination after sexual assault: protocol for a mixed methods study.
Fuente:Bmj Open
Tipo de trabajo:Revisión
Extracto:
Research findings
from the interviews will be shared with those who participate in the
semistructured interviews, if consent is provided.
Claves:FORENSIC MEDICINE, Gender-Based Violence, PUBLIC HEALTH, Patients, SEXUAL MEDICINE
Cita:BMJ Open 2025 Feb 26; 15 (2) : e089478.
Autor/es:Stewart, Mary Louise (a) Shackel, Rita (b)
institución:(a) The University of Sydney Law School, The University of Sydney, Sydney, New South Wales, Australia mste8674@uni.sydney.edu.au. (b) Prevention and Response to Violence, Abuse and Neglect, Northern Sydney Local Health District, St Leonards, New South Wales, Australia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Ventilator settings for fibreoptic bronchoscopy during mechanical ventilation: a study protocol for a pragmatic randomised double-blind controlled trial VentSetFib.
Ventilator settings for fibreoptic bronchoscopy during mechanical ventilation: a study protocol for a pragmatic randomised double-blind controlled trial VentSetFib.
institución:(a) Critical Care Medicine, Hospital Centre Arras, Arras, Hauts-de-France, France malcolm.LEMYZE@gh-artoisternois.fr. (b) Critical Care Medicine, Hospital Centre Arras, Arras, Hauts-de-France, France.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
AXL promotes lymphangiogenesis by amplifying VEGF-C-mediated AKT pathway.
AXL promotes lymphangiogenesis by amplifying VEGF-C-mediated AKT pathway.
Fuente:Cellular and Molecular Life Sciences Cmls
Extracto:
Furthermore, the identification of AXL
expression within a distinct LEC subpopulation, particularly in the context of
metastasis, underscores the intricate interplay between AXL signaling and
lymphatic dynamics within the lymph node microenvironment.
institución:(a) Laboratory of Tumor and Development Biology, GIGA-Cancer, Liege University, Liege, Belgium. (b) Laboratory of Tumor and Development Biology, GIGA-Cancer, Liege University, Liege, Belgium.
Conflicto:Declarations. Ethical approval: Animal experiments were performed in compliance with the Animal Ethical rules of the University of Liège (Liège, Belgium) after approval of the local Animal Ethical Committee (N°21-2361 and 17-1993). Consent to participate: Not applicable. Consent to publish: Not applicable. Competing interests: The authors declare that no conflict of interest exists.
Chemical signal diversity in male sand lizards (Lacerta agilis) along an urbanization gradient.
Chemical signal diversity in male sand lizards (Lacerta agilis) along an urbanization gradient.
Fuente:Scientific Reports
Extracto:
Our study provides insight on how environmental conditions imposed
by urban-rural gradients may modulate chemical communication in vertebrates.
Claves:Body condition, Chemical communication, Femoral glands, Habitat, Lacertidae, Pheromone
institución:(a) Faculty of Biology and Environmental Protection, Department of Ecology and Vertebrate Zoology, University of Lodz, 90-237, Lodz, Poland. alejandro.ibanez@biol.uni.lodz.pl. (b) Department of Comparative Anatomy, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University, Kraków, Poland.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Inhibition of autophagy in platelets as a therapeutic strategy preventing hypoxia induced thrombosis.
Inhibition of autophagy in platelets as a therapeutic strategy preventing hypoxia induced thrombosis.
Fuente:Scientific Reports
Extracto:
Hence, we propose that repurposing of CQ can attenuate
hypoxia-induced thrombosis through inhibition of autophagy and can be explored as
an effective therapeutic alternative.
Autor/es:Bandyopadhyay, Propanna (a) Katakia, Yash T (b)
institución:(a) Department of Biological Sciences, Birla Institute of Technology and Science (BITS Pilani), Pilani Campus, Pilani, Rajasthan, 333031, India. (b) Department of Biological Sciences, Birla Institute of Technology and Science (BITS Pilani), Pilani Campus, Pilani, Rajasthan, 333031, India.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Inflammatory biomarker correlations and prognosis in high-risk gastrointestinal stromal tumor patients: a multicenter retrospective analysis.
Inflammatory biomarker correlations and prognosis in high-risk gastrointestinal stromal tumor patients: a multicenter retrospective analysis.
Fuente:Bmc Gastroenterology
Extracto:
A close correlation between young age, low
preoperative PNI, high mitotic index, and lack of IM treatment had an unfavorable
prognosis in high-risk GIST patients. Notably, the PNI was identified as a
potential additional prognostic factor, enhancing the accuracy of predicting
treatment efficacy and patient outcomes in high-risk patients with GISTs.
Therefore, we advocate for the serious consideration of the PNI as a valuable
addition to standard clinical practice for managing high-risk GIST patients.
institución:(a) Department of Surgical Oncology II, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, 750004, China. (b) Department of Surgical Oncology II, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, 750004, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Prevalence, sub-types, and associated factors of anemia among inpatients at a tertiary psychiatric hospital in Tanzania: a cross-sectional study.
Prevalence, sub-types, and associated factors of anemia among inpatients at a tertiary psychiatric hospital in Tanzania: a cross-sectional study.
Fuente:Bmc Psychiatry
Extracto:
Comprehensive care strategies addressing anemia among psychiatric
inpatients are crucial, extending beyond psychiatric symptoms to address factors
related to prolonged admission, such as nutritional considerations. It is
recommended that regular screening for anemia be implemented among psychiatric
inpatients and efforts should be made to investigate and address the underlying
causes of anemia among this population.
Claves:Anemia, Dodoma, Factors, Prevalence, Psychiatric patients, Severity, Tanzania, Type of anemia
Cita:BMC Psychiatry 2025 Feb 26; 25 (1) : 179.
Autor/es:Msigwa, Valeria (a) Morawej, Zahra (b)
institución:(a) Department of Psychiatry and Mental Health, School of Medicine and Dentistry, The University of Dodoma, Dodoma, Tanzania. (b) Department of Psychiatry, Faculty of Medicine, Hubert Kairuki Memorial University, Dar es Salaam, Tanzania.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Utilization of second medical opinions as a function of the payment method.
Utilization of second medical opinions as a function of the payment method.
Fuente:Bmc Health Services Research
Extracto:
In line with the RAND Corporation
HIE, we show that incentive structures, such as provider payment methods, can
explain some of the variability seen in seeking specialists across health plans
or payment tracks. Considerations other than cost, such as geographic distance
from the service provider, play a role in deciding on the mode-of-payment for a
SO. Analyzing utilization patterns can improve the tracking of regulations'
consequences on expenditure, policy, clinical outcomes, and patient satisfaction.
Claves:Co-payment, Payment track, Reimbursement, Second opinion, Voluntary health insurance
Cita:BMC Health Serv Res 2025 Feb 26; 25 (1) : 321.
Autor/es:Shmueli, Liora (a) Horev, Tuvia (b)
institución:(a) Department of Management, Bar-Ilan University, Ramat-Gan, 52900, Israel. liora.shmueli@biu.ac.il. (b) Department of Health Policy and Management, Guilford Glazer Faculty of Business and Management, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Autor/es:Hemming, Karla (a) Thompson, Jacqueline Y (b)
institución:(a) Institute of Applied Health Research, University of Birmingham, Birmingham, UK. (b) Institute of Applied Health Research, University of Birmingham, Birmingham, UK. J.Y.Thompson@bham.ac.uk.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Prioritisation of head, neck, and respiratory outcomes in mucopolysaccharidosis type II
Prioritisation of head, neck, and respiratory outcomes in mucopolysaccharidosis type II
Fuente:Orphanet Journal of Rare Diseases
Tipo de trabajo:Consenso
Extracto:
A novel methodology for determining a core outcome set in rare
diseases has been recommended. Both functional and quality of life outcomes were
identified by the three age groups of individuals and/or their parents. Adoption
of these sets of outcomes in future clinical trials and/or clinical practice will
enable comparison of outcomes reported.
Claves:Core outcome set, Head, neck, and respiratory disease, Mucopolysaccharidosis type II (MPS II), Outcome measures, Patient and public involvement, Rare diseases
institución:(a) Paediatric ENT Research, Royal Manchester Children's Hospital, Manchester University NHS Foundation Trust, Manchester, M13 9WL, UK. james.dempsey@mft.nhs.uk. (b) Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK. james.dempsey@mft.nhs.uk.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Potential for reducing confirmation bias using the OMP model "6-microskills" with verbalizing discordance: a cross-sectional study.
Potential for reducing confirmation bias using the OMP model "6-microskills" with verbalizing discordance: a cross-sectional study.
Fuente:Bmc Medical Education
Extracto:
The
6-microskills method, which added a part encouraging learners to verbalize why
something "does not fit" with a predicted diagnosis, may effectively correct the
confirmation bias associated with diagnostic predictions.
institución:(a) Department of General Medicine, Chiba University Hospital, 1-8-1, Inohana, Chuo-ku, Chiba-City, Chiba, 260-8677, Japan. j.kojima1989@gmail.com. (b) Department of General Medicine, Chiba University Hospital, 1-8-1, Inohana, Chuo-ku, Chiba-City, Chiba, 260-8677, Japan.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Exploring Older Adult Cancer Survivors' Digital Information Needs: Qualitative Pilot Study.
Exploring Older Adult Cancer Survivors' Digital Information Needs: Qualitative Pilot Study.
Fuente:Jmir Cancer
Extracto:
Overall, this pilot study confirmed the utility of DHTs
in enhancing the connection of older adult cancer survivors to their health care
needs. Importantly, this connection exists on a continuum, and providing greater
access to technologies, in combination with human support, leads to feelings of
empowerment. DHTs are an important aspect of contemporary health care; yet, these
technologies must be seen as complementary and not as replacements for human
interaction. Otherwise, we risk dehumanizing patients and disconnecting them from
the care that they need and deserve.
Claves:aging, cancer survivors, digital health literacy, digital health technologies, older adults, pilot study, qualitative, semistructured interview
Cita:JMIR Cancer 2025 Feb 27; 11 : e59391.
Autor/es:Newton, Lorelei (a) Monkman, Helen (b)
institución:(a) School of Nursing, University of Victoria, PO Box 1700 STN CSC, Victoria, BC, V8W 2Y2, Canada, 1 250-721-6462, 1 250-721-6231. (b) School of Health Information Science, University of Victoria, Victoria, BC, Canada.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Tumor cell-derived EMP1 is essential for cancer-associated fibroblast infiltration in tumor microenvironment of triple-negative breast cancer.
Tumor cell-derived EMP1 is essential for cancer-associated fibroblast infiltration in tumor microenvironment of triple-negative breast cancer.
Fuente:Cell Death & Disease
Extracto:
Targeted inhibition of EMP1 by
suppressing CAF infiltration is a promising strategy for TNBC treatment.
Cita:Cell Death Dis 2025 Feb 27; 16 (1) : 143.
Autor/es:Wang, Qi (a) Li, Dandan (b)
institución:(a) Research Center for High-Altitude Medicine, Key Laboratory of High-Altitude Medicine, Ministry of Education, Laboratory for High Altitude Medicine of Qinghai Province, Key Laboratory of Application and Foundation for High Altitude Medicine Research in Qinghai Province (Qinghai-Utah Joint Research Key Lab for High-Altitude Medicine), Qinghai University, Xining, China. (b) Department of Pathology, Renmin Hospital, Hubei University of Medicine, Shiyan, Hubei, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Association of the systemic immune-inflammation index with clinical outcomes in acute myocardial infarction patients with hypertension.
Association of the systemic immune-inflammation index with clinical outcomes in acute myocardial infarction patients with hypertension.
Fuente:Bmc Immunology
Extracto:
SII was substantially correlated with
30-day all-cause mortality, 365-day all-cause mortality, in-hospital congestive
heart failure, and cardiogenic shock in patients who had both hypertension and
acute myocardial infarction. In individuals with acute myocardial infarction and
hypertension, a greater SII would be regarded as an independent risk factor for a
higher death rate.
institución:(a) Department of Cardiology, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, 030032, China. (b) Department of Cardiology, First Affiliated Hospital of Xi'an Jiao Tong University, Yanta West Road 277, Xi'an, 710061, PR China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Assessing non-inferiority for binary matched-pairs data with missing values: a powerful and flexible GEE approach based on the risk difference.
Assessing non-inferiority for binary matched-pairs data with missing values: a powerful and flexible GEE approach based on the risk difference.
Fuente:Bmc Medical Research Methodology
Extracto:
Our results indicate that the proposed GEE approach is a powerful alternative to
existing methods and can be used for testing non-inferiority, even if the initial
sample size calculation was based on a different statistical method. Furthermore,
it increases the analytical flexibility by allowing the inclusion of additional
covariates, in contrast to other methods.
Cita:BMC Med Res Methodol 2025 Feb 27; 25 (1) : 53.
Autor/es:Hengelbrock, Johannes (a) Konietschke, Frank (b)
institución:(a) Institute of Biometry and Clinical Epidemiology, Charité - Universitätsmedizin, Freie Universität Berlin and Humboldt-Universität Zu Berlin, Charitéplatz 1, 10117, Berlin, Germany. johannes.hengelbrock@charite.de. (b) Institute of Biometry and Clinical Epidemiology, Charité - Universitätsmedizin, Freie Universität Berlin and Humboldt-Universität Zu Berlin, Charitéplatz 1, 10117, Berlin, Germany.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
