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La creciente cantidad de artículos con Acceso Abierto (Open
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fundamentales. Para facilitarlo, profesionales biomédicos de SIIC
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SIIC creó, produjo y opera con exclusividad el software TCA para la
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fuente, fechas de publicación y selección, definición de la fuente,
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Si bien la mayoría de los textos seleccionados corresponden a
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Sociedad Iberoamericana de Información Científica (SIIC) selects
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renowned sources worldwide and are indexed by SIIC Data
Bases.
The increasing number of Open Access articles widens the reading offer
but, also, such myriad complicates the readers search of fundamental
articles. To facilitate this, SIIC biomedical professionals daily
consult a profuse amount of documents that will feed
Authorized Full Texts (TCA, Spanish acronym).
The citations of the AFT section link legally, authorized and free of
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SIIC created, produced and handles the AFT software that deciphers
the various documentary fields that form part of the structure of a
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dates, source definition, query limitations, summary in Spanish,
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While most of the selected texts belong to original articles,
reviews, and guidelines, readers will also find commentaries,
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that may lead to discussions or clarifications.
Advanced multi-modal mass spectrometry imaging reveals functional differences of placental villous compartments at microscale resolution.
Advanced multi-modal mass spectrometry imaging reveals functional differences of placental villous compartments at microscale resolution.
Fuente:Nature Communications
Extracto:
Integration across our advanced MIPI imaging modalities enables the
reconstruction of active biological pathways of molecular synthesis and
maternal-fetal signaling across morphologically distinct placental villous
compartments with micrometer-scale resolution.
Cita:Nat Commun 2025 Feb 28; 16 (1) : 2061.
Autor/es:Veličković, Marija (a) Kadam, Leena (b)
institución:(a) The Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, WA, USA. (b) Department of Obstetrics & Gynecology, Oregon Health & Science University, Portland, OR, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
A customized bed based stand alone array of optically pumped magnetometers for fetal magnetocardiography measurements.
A customized bed based stand alone array of optically pumped magnetometers for fetal magnetocardiography measurements.
Fuente:Scientific Reports
Extracto:
While
additional translational research is needed, the outcome of this study can
further facilitate the development of a non-cryogenic low-cost smaller footprint
device to increase the use of OPMs for fetal research and clinical applications.
Autor/es:Escalona-Vargas, Diana (a) Ramirez, Alberto (b)
institución:(a) Department of Pediatrics, Division of Neurology, University of Arkansas for Medical Sciences, Arkansas Children's Hospital, Little Rock, AR, USA. (b) Department of Obstetrics and Gynecology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Identification of FZD7 as a potential ferroptosis-related diagnostic gene in endometriosis by bioinformatics analysis.
Identification of FZD7 as a potential ferroptosis-related diagnostic gene in endometriosis by bioinformatics analysis.
Fuente:Scientific Reports
Extracto:
The study identified an ferroptosis repressor gene,
FZD7, validated in five EMS transcriptome datasets, which is significantly
up-regulated in ectopic lesions of EMS and is a potential target for the
treatment of EMS.
institución:(a) Department of Gynecology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China. (b) Biomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Digitization in nursing processes and the use of clinical decision support systems: do they improve perinatal indicators?
Digitization in nursing processes and the use of clinical decision support systems: do they improve perinatal indicators?
Fuente:Bmc Pregnancy and Childbirth
Extracto:
In the comparisons of the
World Health Organization safe childbirth checklist usage rates, rates of infants
discharged following exclusive breastfeeding, and rates of mother-infant pairs
starting skin-to-skin contact within one hour after delivery according to the
THQIS records in 2021, 2022, and 2023, the increase from 2021 to 2022 and the
increase from the average of 2021-2022 to 2023 were found statistically
significant. Digitization in nursing processes and the use of the CDSS were found
to be highly beneficial for improving the perinatal indicators examined in the
present study.
Claves:Clinical decision support systems, Digitization, Nursing information systems, Nursing process, Outcomes
Cita:BMC Pregnancy Childbirth 2025 Feb 28; 25 (1) : 218.
Autor/es:Özkan, Asibe (a) Acar, Zehra (b)
institución:(a) Faculty of Nursing, Department of Obstetrics and Women's Health Nursing, University of Health Sciences, Hamidiye, Istanbul, Turkey. asibe.ozkan@sbu.edu.tr. (b) Faculty of Nursing, Department of Obstetrics and Women's Health Nursing, University of Health Sciences, Hamidiye, Istanbul, Turkey.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Predicting outcomes of expectant and medical management in early pregnancy miscarriage using machine learning to develop and validate multivariable clinical prediction models.
Predicting outcomes of expectant and medical management in early pregnancy miscarriage using machine learning to develop and validate multivariable clinical prediction models.
Fuente:Bmc Pregnancy and Childbirth
Extracto:
Performance of our expectant and medical
miscarriage management ML models demonstrate consistency across validation and
external test sets. These ML methods, validated and externally tested, have the
potential to offer personalised prediction outcome of expectant and medical
management of miscarriage.
Claves:Expectant management, Machine learning, Medical management, Miscarriage
Cita:BMC Pregnancy Childbirth 2025 Feb 28; 25 (1) : 225.
institución:(a) Queen Charlotte's and Chelsea Hospital, Imperial College, London, W12 0HS, UK. sughashini.murugesu@nhs.net. (b) Department of Metabolism, Digestion and Reproduction, Imperial College London, Du Cane Road, London, W12 0NN, UK. sughashini.murugesu@nhs.net.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
The association between interpregnancy intervals and preterm birth
The association between interpregnancy intervals and preterm birth
Fuente:Bmc Pregnancy and Childbirth
Tipo de trabajo:Revisión sistemática
Extracto:
IPIs of 24-29 months significantly reduce the risk of preterm birth,
suggesting a potential target range for family planning and clinical
recommendations. TRIAL REGISTRATION: Not applicable.
Cita:BMC Pregnancy Childbirth 2025 Feb 28; 25 (1) : 226.
Autor/es:Wen, Xueheng (a) Liang, Weilun (b)
institución:(a) School of Nursing, Southern Medical University, 1023 Shatai South Road, Baiyun District, Guangzhou City, 510515, Guangdong Province, China. (b) Department of Gynecology, and Department of Surgery, Shenzhen Futian District Maternity&Child Healthcare Hospital, Shenzhen, 518045, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Extracto:
This meta-analysis confirmed that maternal serum GlyFn
levels are significantly higher in patients with PE and exhibit high diagnostic
accuracy for PE diagnosis, suggesting its potential as a biomarker for screening
and diagnosing PE.
Cita:BMC Pregnancy Childbirth 2025 Feb 28; 25 (1) : 228.
Autor/es:Liao, Lingyun (a) Liu, Min (b)
institución:(a) Department of Obstetrics and Gynecology, West China Second University Hospital, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, (Sichuan University) of Ministry of Education, Chengdu, China. (b) NHC Key Laboratory of Chronobiology, Sichuan University, Chengdu, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Antibiotic susceptibility and risk factors for listeriosis in women with spontaneous abortion in Ugandan tertiary hospitals: a cross-sectional study.
Antibiotic susceptibility and risk factors for listeriosis in women with spontaneous abortion in Ugandan tertiary hospitals: a cross-sectional study.
Fuente:Bmc Pregnancy and Childbirth
Extracto:
This study provides critical insights into the prevalence, antibiotic resistance
patterns, and risk factors for listeriosis among Ugandan women with spontaneous
abortion. Findings underscore the need for targeted public health interventions
and antibiotic stewardship to mitigate the impact of this infection.
Non-invasive diagnosis of vulvar dysplasia using cervical methylation markers-a case control study.
Non-invasive diagnosis of vulvar dysplasia using cervical methylation markers-a case control study.
Fuente:Bmc Medicine
Extracto:
The
findings suggest that the methylation markers comprising GynTect® may be suitable
for detecting vulvar neoplasia, as they exhibit high sensitivity. Nonetheless,
adjustments are needed for comparable specificity. Lichen should be considered in
result interpretation, and the kit should be used with caution for patients with
lichen. Moreover, we observed methylation changes as an early event with the
highest positivity of VLSIL. Surprisingly, changes in methylation pattern are not
as local as presumed. Cervical SIL led to changed methylation in the vulva.
Patients with positive kit results should be monitored regularly for all genital
dysplasia. This sheds new light on the epigenetics in cancer.
Claves:Cancer of cervix and vulva, Cervical dysplasia, Cervical smear, DNA methylation, Epigenetic, GynTect®, Vulvar dysplasia, Vulvar smear
Cita:BMC Med 2025 Feb 28; 23 (1) : 128.
Autor/es:Becker, Sabeth (a) Dübbel, Lena (b)
institución:(a) University Clinic of Gynaecology and Obstetrics, Carl von Ossietzky Universität Oldenburg, Ammerländer Heerstraße 114-118, 26129, Oldenburg, Germany. (b) University Clinic of Gynaecology and Obstetrics, Klinikum Oldenburg, Rahel-Straus-Straße 10, 26133, Oldenburg, Germany.
Conflicto:Declarations. Ethics approval and consent to participate: All patients were diagnosed and managed in the Department of Gynaecology and Obstetrics at Oldenburg University Hospital, and they agreed in written form to use the retrieved samples and data for research purposes. This study was approved by the Medical Ethics Committee of the Carl-von-Ossietzky University of Oldenburg (ethics vote no. 2017-114 and...
2020-187) and complies with the ethical principles for medical research of the Declaration of Helsinki. This retrospective study is registered at the German Clinical Trials Register (DRKS00024987). Consent for publication: Not applicable. Competing interests: J.H. and K.K. are employees of oncgnostics GmbH. The employees of oncgnostics had no influence on study design, sample collection, analyses or interpretation of data and were not involved in drafting the manuscript. In addition, oncgnostics GmbH sent the GynTect kits that were used.
Low pretreatment prognostic nutritional index predicts unfavorable survival in stage III-IVA squamous cervical cancer undergoing chemoradiotherapy.
Low pretreatment prognostic nutritional index predicts unfavorable survival in stage III-IVA squamous cervical cancer undergoing chemoradiotherapy.
Fuente:Bmc Cancer
Tipo de trabajo:Revisión
Extracto:
PNI, a readily obtainable metric based on albumin and lymphocyte
count, can serve as a predictor of survival in HR-LACC patients undergoing
concurrent chemoradiotherapy. Further research is necessary to ascertain whether
optimizing pretreatment nutritional status, a modifiable factor, can enhance
outcomes in these high-risk patients.
Claves:Advanced stage, Biomarker, Cervical cancer, Chemoradiotherapy, Prognostic nutritional index
Cita:BMC Cancer 2025 Feb 28; 25 (1) : 377.
Autor/es:Jia, Shuang-Zheng (a) Yang, Xue-Jiao (b)
institución:(a) Department of Gynecologic Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P. R. China. (b) Department of Gynecologic Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P. R. China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Impact of maternal COVID-19 infection on offspring immunity and maternal-fetal outcomes at different pregnancy stages
Impact of maternal COVID-19 infection on offspring immunity and maternal-fetal outcomes at different pregnancy stages
Fuente:Bmc Pregnancy and Childbirth
Tipo de trabajo:Estudio de cohortes
Extracto:
No adverse outcomes were observed in mothers or infants at any stage
of maternal SARS-CoV-2 infection. Antibodies in umbilical cord blood and breast
milk may offer passive immunity to newborns for 1-3 months. Reinfection during
pregnancy may extend this immunity without raising the risk of adverse outcomes.
Claves:Antibody, COVID-19, Infant, Pregnancy
Cita:BMC Pregnancy Childbirth 2025 Feb 28; 25 (1) : 219.
Autor/es:Sun, Yushan (a) Luo, Xin (b)
institución:(a) Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Chongqing Medical University, Chongqing, 401120, China. (b) Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Chongqing Medical University, Chongqing, 401120, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Relationship Between Pregnant Women's eHealth Literacy and Their Attitudes Toward Sexuality.
Relationship Between Pregnant Women's eHealth Literacy and Their Attitudes Toward Sexuality.
Fuente:Brain and Behavior
Extracto:
To
have the ability to protect and improve maternal and fetal health by making
appropriate interventions, it is important for health professionals to know the
information requirements and sources of pregnant women. It is recommended to
determine the eHealth literacy levels of pregnant women and assess their
sexuality-related attitudes in their routine follow-ups.
institución:(a) Konya City Hospital, Konya, Turkey. (b) Department of Obstetrics and Gynaecology Nursing, Nursing Faculty, Necmettin Erbakan University, Konya, Turkey.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Cita:Asian Pac J Cancer Prev 2025 Feb 1; 26 (2) : 625-630.
Autor/es:Hamidah, Hamidah (a) Rauf, Syahrul (b)
institución:(a) Department of Midwifery, Faculty of Medicine and Health, Universitas Muhammadiyah Jakarta, Jakarta, Indonesia. (b) Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia.
Analysis of prognosis and related influencing factors of different surgical approaches for early cervical cancer.
Analysis of prognosis and related influencing factors of different surgical approaches for early cervical cancer.
Fuente:Journal of Cancer Research and Clinical Oncology
Extracto:
The 5-year overall survival rate
of patients with early CC was 89.0%. Laparoscopic surgery did not adversely
affect the prognosis of early CC patients. Both surgical approaches demonstrate
favorable prospects for treating early CC. Prognosis in early CC is influenced by
clinical stage, vascular invasion, and tumor diameter, rather than the surgical
approach used.
Cita:J Cancer Res Clin Oncol 2025 Mar 1; 151 (3) : 97.
Autor/es:Ou, Lingling (a) He, Lulu (b)
institución:(a) Department of Gynecology, Guangdong Women and Children Hospital, Guangzhou, China. (b) Jiangmen People's Hospita, Jiangmen, China.
Conflicto:Declarations. Conflict of interest: The author(s) indicated no potential conflicts of interest related to this article. Ethical approval: All patients provided informed consent and agreed to participate in the study. The present study was approved by the Guangdong Women and Children Hospital Ethics Committee (reference number, 202301372). Consent to participate statement: All participants gave written informed consent.
Associations of prenatal metal exposure with child neurodevelopment and mediation by perturbation of metabolic pathways.
Associations of prenatal metal exposure with child neurodevelopment and mediation by perturbation of metabolic pathways.
Fuente:Nature Communications
Extracto:
Histidine,
beta-alanine, purine, and pyrimidine metabolism significantly mediated the above
associations, suggesting that disturbances in amino acids, neurotransmitter and
neuroendocrine metabolism may be important mediators in contributing to impaired
neurodevelopment of children.
Cita:Nat Commun 2025 Mar 1; 16 (1) : 2089.
Autor/es:Xie, Ya (a) Xiao, Han (b)
institución:(a) Department of Obstetrics, Wuhan Children's Hospital (Wuhan Maternal and Child Health care Hospital), Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, PR China. (b) School of Public Health, Tongji Medical College, Huazhong University of Science and Technology / Key Laboratory of Environment and Health, Ministry of Education / Key Laboratory of Environmental Pollution and Health Effects of the Ministry of Ecology and Environment, Wuhan, Hubei, PR China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Multi-omics integration analysis and association study reveal the potential of ADIPOQ function in gestational diabetes mellitus.
Multi-omics integration analysis and association study reveal the potential of ADIPOQ function in gestational diabetes mellitus.
Fuente:Nutrition & Diabetes
Extracto:
The findings
of our study indicate a correlation between SNPs of ADIPOQ in GDM patients, and
ADIPOQ is involved in the transcriptional regulation of GDM.
Cita:Nutr Diabetes 2025 Mar 1; 15 (1) : 9.
Autor/es:Li, Xiaoying (a) Jia, Tianshuang (b)
institución:(a) Cancer Center, Department of Ultrasound Medicine, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), No.158, Shangtang Road, Gongshu District, Hangzhou, Zhejiang, China. (b) Cancer Center, Department of Ultrasound Medicine, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), No.158, Shangtang Road, Gongshu District, Hangzhou, Zhejiang, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
General lightweight framework for vision foundation model supporting multi-task and multi-center medical image analysis.
General lightweight framework for vision foundation model supporting multi-task and multi-center medical image analysis.
Fuente:Nature Communications
Extracto:
These results
underscore the potential of VFMGL in advancing the efficacy and reliability of
AI-driven medical diagnostics.
Cita:Nat Commun 2025 Mar 1; 16 (1) : 2097.
Autor/es:Lu, Senliang (a) Chen, Yehang (b)
institución:(a) Laboratory of Intelligent Detection and Information Processing, Guilin University of Aerospace Technology, Guilin, Guangxi, China. (b) Jiangmen Key Laboratory of Artificial Intelligence in Medical Image Computation and Application, Jiangmen Central Hospital, Jiangmen, Guangdong, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
ALKBH1 knockdown promotes the growth, migration and invasion of HTR-8/SVneo cells through regulating the m5C modification PSMD14.
ALKBH1 knockdown promotes the growth, migration and invasion of HTR-8/SVneo cells through regulating the m5C modification PSMD14.
Fuente:Scientific Reports
Extracto:
ALKBH1 mediated m5C levels were decreased in the
hypoxia treated HTR-8/SVneo cells, which further decreased the cell viability,
migration and invasion abilities through targeting the PSMD14 levels.
institución:(a) Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Zhengzhou University or Maternal and Child Hospital of Henan Province, No.10, Kangfuqian Street, Zhengzhou City, 450001, Henan, China. (b) Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Zhengzhou University or Maternal and Child Hospital of Henan Province, No.10, Kangfuqian Street, Zhengzhou City, 450001, Henan, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Identification of blood-derived exosomal tumor RNA signatures as noninvasive diagnostic biomarkers for multi-cancer: a multi-phase, multi-center study.
Identification of blood-derived exosomal tumor RNA signatures as noninvasive diagnostic biomarkers for multi-cancer: a multi-phase, multi-center study.
Fuente:Molecular Cancer
Extracto:
The study demonstrates
the robust potential of exosomal RNA as a minimally invasive biomarker resource
for cancer detection. The developed ETR.sig platform offers a promising tool for
precision oncology and broad-spectrum cancer screening, integrating advanced
computational models with nanoscale vesicle biology for accurate and rapid
diagnosis.
Claves:Biomarker, Cancer detection, Cancer localization, Exosomal tumor RNA signatures, Exosome, Multi-cancer
Cita:Mol Cancer 2025 Mar 1; 24 (1) : 60.
Autor/es:Wang, Fubo (a) Wang, Chengbang (b)
institución:(a) Center for Genomic and Personalized Medicine, Guangxi Key Laboratory for Genomic and Personalized Medicine, Guangxi Collaborative Innovation Center for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, 530021, Guangxi, China. wangfubo@gxmu.edu.cn. (b) Department of Urology, The First Affiliated Hospital of Guangxi Medical University, Guangxi Medical University, Guangxi, 530021, China. wangfubo@gxmu.edu.cn.
Conflicto:Declarations. Ethics approval and consent to participate: This study obtained approval from the Clinical Research Ethics Committees of Guangxi Medical University (Approval Numbers: GXMU2022-0154). Written informed consent was obtained from all participants. Competing interests: F.B. Wang, Z.N. Mo, C.B. Wang, S.H. Chen and C.M. Wei have filed a Chinese patent application related to this work (Application number: 202410931244.5).
Prognostic Value of Circulating Lymphocyte Subsets in Cervical Cancer Following Postoperative Radiotherapy.
Prognostic Value of Circulating Lymphocyte Subsets in Cervical Cancer Following Postoperative Radiotherapy.
Fuente:International Journal of Medical Sciences
Extracto:
Conclusions: Our
study found that pre-treatment levels of circulating NK cell counts and
proportions serve as promising prognostic biomarkers for cervical cancer patients
undergoing postoperative radiotherapy.
institución:(a) Department of Radiation Oncology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. (b) Department of Radiation Oncology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Conflicto:Competing Interests: The authors have declared that no competing interest exists.
