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La creciente cantidad de artículos con Acceso Abierto (Open
Access) amplía la oferta de lectura pero a su vez también, entre
tanta abundancia, complica al lector en su encuentro con los estudios
fundamentales. Para facilitarlo, profesionales biomédicos de SIIC
consultan diariamente una profusa cantidad de documentos que nutrirán
Textos completos autorizados (TCA).
Las citas de la sección TCA enlazan de manera legal, autorizada y
gratuita con los textos completos (full text) publicados en
los sitios oficiales de sus respectivas fuentes.
SIIC creó, produjo y opera con exclusividad el software TCA para la
interpretación de los diversos campos documentales que integran la
estructura de un estudio: especialidad, modalidad del estudio,
fuente, fechas de publicación y selección, definición de la fuente,
limitaciones de consulta, resumen en castellano, etc.
Si bien la mayoría de los textos seleccionados corresponden a
artículos originales, revisiones y guías, los lectores también
encontrarán comentarios, entrevistas, notas periodísticas, cartas a
autores u otros textos precursores de debates o aclaratorios.
Sociedad Iberoamericana de Información Científica (SIIC) selects
complete quality-full texts which have been recently published in
renowned sources worldwide and are indexed by SIIC Data
Bases.
The increasing number of Open Access articles widens the reading offer
but, also, such myriad complicates the readers search of fundamental
articles. To facilitate this, SIIC biomedical professionals daily
consult a profuse amount of documents that will feed
Authorized Full Texts (TCA, Spanish acronym).
The citations of the AFT section link legally, authorized and free of
charge with the full texts published in the official web sites of
their corresponding sources.
SIIC created, produced and handles the AFT software that deciphers
the various documentary fields that form part of the structure of a
study: specialty, study style, source, publication and selection
dates, source definition, query limitations, summary in Spanish,
etc.
While most of the selected texts belong to original articles,
reviews, and guidelines, readers will also find commentaries,
interviews, journalistic reports, letters to authors or other texts
that may lead to discussions or clarifications.
Carrier Screening and Prenatal Diagnosis for Spinal Muscular Atrophy in Ningde City, Fujian Province.
Carrier Screening and Prenatal Diagnosis for Spinal Muscular Atrophy in Ningde City, Fujian Province.
Fuente:Molecular Genetics & Genomic Medicine
Extracto:
The frequency of SMA mutation
in the Ningde area of Fujian province has been identified, which can provide the
basis for genetic counseling and prenatal diagnosis. Interventional prenatal
genetic diagnosis for high-risk fetuses can effectively prevent the birth of
children with SMA and is crucial for preventing and controlling birth defects.
Cita:Mol Genet Genomic Med 2025 Feb; 13 (2) : e70077.
Autor/es:Lu, JiaoJiao (a) Zheng, Xian (b)
institución:(a) Department of Prenatal Diagnosis, Ningde Municipal Hospital of Ningde Normal University, Ningde, Fujian, China. (b) Department of Prenatal Diagnosis, Ningde Municipal Hospital of Ningde Normal University, Ningde, Fujian, China.
Identification of genes involved in energy metabolism in preeclampsia and discovery of early biomarkers.
Identification of genes involved in energy metabolism in preeclampsia and discovery of early biomarkers.
Fuente:Frontiers in Immunology
Extracto:
Dysregulated energy metabolism-related genes may contribute
to preeclampsia through metabolic and immune changes. Identifying these genes
aids in understanding preeclampsia's molecular basis and early diagnosis. Future
studies should validate these markers in larger cohorts and explore targeted
treatments.
Claves:biomarkers, energy metabolism, gene expression, immune infiltration, preeclampsia
Cita:Front Immunol 2025; 16 : 1496046.
Autor/es:Li, Ruohua (a) Zhou, Cuixia (b)
institución:(a) Department of Gynecology and Obstetrics, The Third Affiliated Hospital of Wenzhou Medical University, Rui'an, China. (b) Department of Gynecology and Obstetrics, The Third Affiliated Hospital of Wenzhou Medical University, Rui'an, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Single-cell transcriptomic atlas of different endometriosis indicating that an interaction between endometriosis-associated mesothelial cells (EAMCs) and ectopic stromal cells may influence progesterone resistance.
Single-cell transcriptomic atlas of different endometriosis indicating that an interaction between endometriosis-associated mesothelial cells (EAMCs) and ectopic stromal cells may influence progesterone resistance.
Fuente:Clinical and Translational Medicine
Extracto:
Our study comprehensively characterises the heterogeneity of the different
pathologic types of endometriosis and offers valuable insights into the
underlying mechanisms contributing to variations in progesterone resistance
across the three subtypes. KEY POINTS: Single-cell RNA (ScRNA) atlas across types
of endometriosis is established. Mesothelial cells are founded in ovarian
endometriosis. Endometriosis-associated mesothelial cells (EAMCs) experience
various level of epithelial-mesenchymal transition (EMT) process in different
subtypes. EAMCs may exert an influence on progesterone resistance in stromal
cells through intercellular communication mediated by the FN1-AKT pathway.
institución:(a) Department of Obstetrics and Gynecology, Capital Medical University Affiliated Beijing Chaoyang Hospital, Beijing, China. (b) Department of Obstetrics and Gynecology, Capital Medical University Affiliated Beijing Chaoyang Hospital, Beijing, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Navigating Metabolic Challenges in Ovarian Cancer: Insights and Innovations in Drug Repurposing.
Navigating Metabolic Challenges in Ovarian Cancer: Insights and Innovations in Drug Repurposing.
Fuente:Cancer Medicine
Tipo de trabajo:Revisión
Extracto:
Drug repurposing
offers a promising strategy to overcome chemoresistance and improve patient
outcomes. Future research should focus on unraveling the complex metabolic
networks in OC to develop innovative, targeted therapies that can enhance
treatment efficacy and patient survival.
Claves:drug repurposing strategy, metabolic reprogramming, metabolic syndrome, ovarian cancer
Cita:Cancer Med 2025 Feb; 14 (4) : e70681.
Autor/es:Mikhael, Sara (a) Daoud, Georges (b)
institución:(a) Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut, Lebanon. (b) Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut, Lebanon.
Regional nerve block in postoperative analgesia after cesarean section
Regional nerve block in postoperative analgesia after cesarean section
Fuente:Medicine
Tipo de trabajo:Revisión
Extracto:
This review provides an
overview of the regional nerve block techniques used for postoperative analgesia
following cesarean section, discusses their benefits and drawbacks, and provides
a reference for choosing postoperative pain management following cesarean
delivery, offering a hopeful outlook for improved patient care.
Cita:Medicine (Baltimore) 2024 Dec 27; 103 (52) : e41159.
Autor/es:Qin, Yongyi (a) Yang, Yujiao (b)
institución:(a) Clinical School of North Sichuan Medical College, Nanchong, Sichuan, China. (b) Clinical School of North Sichuan Medical College, Nanchong, Sichuan, China.
Conflicto:The authors have no funding and conflicts of interest to disclose.
Extracto:
Furthermore, this
study will describe the potential use of ultrasound-guided hysteroscopic excision
of cervical lesions and transvaginal hysteroscopic excision of cervical lesions
as a treatment modality for lobular endocervical glandular hyperplasia patients
with fertility needs.
Cita:Medicine (Baltimore) 2024 Dec 27; 103 (52) : e40968.
Autor/es:Tang, Shenglan (a) Jiang, Xuelu (b)
institución:(a) Department of the First School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, People's Republic of China. (b) The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, Zhejiang Province, People's Republic of China.
Conflicto:The authors have no funding and conflicts of interest to disclose.
A Health Professional Mentorship Platform to Improve Equitable Access to Abortion: Development, Usability, and Content Evaluation.
A Health Professional Mentorship Platform to Improve Equitable Access to Abortion: Development, Usability, and Content Evaluation.
Fuente:Jmir Human Factors
Tipo de trabajo:Revisión
Extracto:
This platform contains resources that can increase the competencies
of health care professionals to initiate and sustain culturally and contextually
appropriate abortion care for underserved groups while clarifying myths and
misconceptions that often militate against initiating abortion. Our resource also
has the potential to support equitable access to high-quality abortion care,
particularly for those among underserved populations who may have the greatest
unmet need for abortion services yet face the greatest barriers to accessing
care.
institución:(a) School of Nursing, University of British Columbia, Vancouver, BC, Canada. (b) School of Nursing, University of British Columbia, Vancouver, BC, Canada.
Impact of patients' age and comorbidities on prostate cancer overdiagnosis in clinical practice.
Impact of patients' age and comorbidities on prostate cancer overdiagnosis in clinical practice.
Fuente:Plos One
Tipo de trabajo:Estudio clínico
Extracto:
These findings underscore
the high likelihood of overdiagnosis in older patients with elevated PSA levels
and significant comorbidities, highlighting the need for careful consideration of
patient comorbidities before PSA testing.
Cita:PLoS One 2025; 20 (2) : e0315979.
Autor/es:Beltrán, Abraham (a) Parker, Lucy (b)
institución:(a) Department of Public Health, History of Science and Gynecology, Miguel Hernandez University, San Juan de Alicante, Spain. (b) Department of Public Health, History of Science and Gynecology, Miguel Hernandez University, San Juan de Alicante, Spain.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Immunogenic cryptic peptides dominate the antigenic landscape of ovarian cancer.
Immunogenic cryptic peptides dominate the antigenic landscape of ovarian cancer.
Fuente:Science Advances
Extracto:
This study
reveals noncoding cryptic peptides as an important class of immunogenic antigens
in OC.
Cita:Sci Adv 2025 Feb 21; 11 (8) : eads7405.
Autor/es:Raja, Remya (a) Mangalaparthi, Kiran K (b)
institución:(a) Department of Immunology, Mayo Clinic, Phoenix, AZ, USA. (b) Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
Cost-effectiveness analysis of daratumumab plus bortezomib, melphalan and prednisone versus bortezomib, melphalan and prednisone in patients with newly diagnosed multiple myeloma ineligible for stem cell transplantation.
Cost-effectiveness analysis of daratumumab plus bortezomib, melphalan and prednisone versus bortezomib, melphalan and prednisone in patients with newly diagnosed multiple myeloma ineligible for stem cell transplantation.
Fuente:Bmj Open
Extracto:
Compared with VMP, D-VMP is unlikely to be a
cost-effective regimen for patients with NDMM who are ineligible for ASCT from
the US payer's perspective.
Claves:HEALTH ECONOMICS, Health policy, Lymphoma
Cita:BMJ Open 2025 Feb 19; 15 (2) : e076914.
Autor/es:Xie, Dan (a) Zhang, Peng-Fei (b)
institución:(a) Prenatal Diagnosis Center, Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, China. (b) Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
The clinical efficacy and influencing factors of uterine artery embolization in the treatment of different types of uterine adenomyosis.
The clinical efficacy and influencing factors of uterine artery embolization in the treatment of different types of uterine adenomyosis.
Fuente:Scientific Reports
Extracto:
In summary, UAE, as a minimally invasive treatment,
has obvious and significant clinical effects in the treatment of adenomyosis, and
is an important alternative treatment for adenomyosis.
Claves:CA125, Dysmenorrhea, Magnetic resonance imaging, Uterine adenomyosis, Uterine artery embolization
Cita:Sci Rep 2025 Feb 19; 15 (1) : 6027.
Autor/es:Wei, Wen-Jiang (a) Tian, Zuo-Fu (b)
institución:(a) Interventional Vascular Department, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, 466 Xingang Middle Road, Guangzhou, 510317, Guangdong, China. (b) College of Clinical Medicine for Oncology, Fujian Medical University, Fuzhou, 350122, Fujian, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Institute of Convergence Medicine Research, Ewha Womans University Mokdong Hospital, Ewha Womans University School of Medicine, 1071 Anyangcheon-Ro, Yangcheon-Gu, Seoul, 07985, Republic of Korea. jsan@ewha.ac.kr. (b) Department of Surgery, Ewha Womans University Mokdong Hospital, Ewha Womans University School of Medicine, 1071 Anyangcheon-Ro, Yangcheon-Gu, Seoul, 07985, Republic of Korea. jsan@ewha.ac.kr.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Potential drug targets for ovarian cancer identified through Mendelian randomization and colocalization analysis.
Potential drug targets for ovarian cancer identified through Mendelian randomization and colocalization analysis.
Fuente:Journal of Ovarian Research
Extracto:
This study provides proof of a causal relationship
between genetically predicted 44 proteins associated with OC risk, which could
serve as promising drug targets for OC.
Claves:Drug target, Mendelian randomization, Ovarian cancer, Protein
Cita:J Ovarian Res 2025 Feb 19; 18 (1) : 32.
Autor/es:Liu, Sicong (a) Lin, Hao (b)
institución:(a) Department of Obstetrics and Gynecology, School of Medicine, Zhongda Hospital, Southeast University, Nanjing, 210003, China. (b) Department of Clinical Science and Research, School of Medicine, Zhongda Hospital, Southeast University, Nanjing, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Polycystic ovary syndrome and epithelial-mesenchymal transition: Mendelian randomization and single-cell analysis insights.
Polycystic ovary syndrome and epithelial-mesenchymal transition: Mendelian randomization and single-cell analysis insights.
Fuente:Journal of Ovarian Research
Extracto:
This study identified three EMT-RGs: NUCB2, PGF, and
CRIM1, which were associated with a reduced risk of PCOS, with fibroblast
identified as a key cell group in the disease's pathology. This provides new
insights for PCOS research.
institución:(a) Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, China. (b) Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Inhaled methoxyflurane (Penthrox) use in the outpatient and ambulatory setting
Inhaled methoxyflurane (Penthrox) use in the outpatient and ambulatory setting
Fuente:Bmj Open
Tipo de trabajo:Revisión sistemática
Extracto:
Penthrox (methoxyflurane) shows promise as an
analgesic for invasive, elective interventional procedures in the outpatient
setting, although the relative benefits appear to vary depending on intervention
and comparator pain control measures. There is a pressing need for robustly
conducted, large, generalisable multicentre RCTs to evaluate the effectiveness of
Penthrox. PROSPERO REGISTRATION NUMBER: CRD42023404574.
Autor/es:Sairally, Bibi Zeyah Fatemah (a) De Silva, Prathiba M (b)
institución:(a) Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK zeyah.sairally@nhs.net. (b) Obstetrics and Gynaecology, Birmingham Women's and Children's NHS Foundation Trust, Birmingham, UK.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Effect of intensive nutrition training, education and support versus standard therapy in reducing the need for insulin therapy in gestational diabetes (INTENSE-GDM): a protocol for a randomised controlled single-centre trial in Denmark.
Effect of intensive nutrition training, education and support versus standard therapy in reducing the need for insulin therapy in gestational diabetes (INTENSE-GDM): a protocol for a randomised controlled single-centre trial in Denmark.
Fuente:Bmj Open
Tipo de trabajo:Revisión
Extracto:
TRIAL REGISTRATION NUMBER: NCT06127823.
Claves:DIABETES & ENDOCRINOLOGY, Diabetes in pregnancy, Health economics, NUTRITION & DIETETICS, OBSTETRICS
Cita:BMJ Open 2025 Feb 17; 15 (2) : e089231.
Autor/es:Ewers, Bettina (a) Blond, Martin B (b)
institución:(a) Department of Diabetes Care, Steno Diabetes Center Copenhagen, Herlev, Capital Region of Denmark, Denmark bettina.ewers@regionh.dk. (b) Department of Clinical and Translational Research, Copenhagen University Hospital - Steno Diabetes Center Copenhagen, Herlev, Denmark.
Conflicto:Competing interests: Steno Diabetes Center Copenhagen (SDCC) is a hospital providing health services within the public healthcare system. The research project and SDCC are partially funded by the Novo Nordisk Foundation through unrestricted grants. The Novo Nordisk Foundation has no financial interest in the study and has no influence on the (1) study design; (2) collection, analysis and interpretation of...
data; (3) writing of the study report and publication and (4) decision to submit the paper for publication. The investigators have no financial, personal or professional associations that could be perceived as influencing the study. They will not benefit economically from conducting this study and have no competing interest to declare.
Gestational diabetes mellitus in previous pregnancy associated with the risk of large for gestational age and macrosomia in the second pregnancy.
Gestational diabetes mellitus in previous pregnancy associated with the risk of large for gestational age and macrosomia in the second pregnancy.
Fuente:Frontiers in Endocrinology
Extracto:
Previous GDM is strongly linked to LGA and macrosomia
in subsequent pregnancies. However, this relationship is influenced by GWG, prior
LGA history, fetal sex, and maternal age. Managing weight alone may not
sufficiently reduce the risk of LGA or macrosomia for women with a history of
GDM.
Claves:body mass index, gestational diabetes mellitus, gestational weight gain, large for gestational age, macrosomia, multipara
institución:(a) Center of Obstetrics and Gynecology, Peking University Shenzhen Hospital, Shenzhen, Guangdong, China. (b) Institute of Obstetrics and Gynecology, Shenzhen Peking University-Hong Kong University of Science and Technology (PKU-HKUST) Medical Center, Shenzhen, Guangdong, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Workload in antenatal care before and after implementation of an electronic decision support system: an observed time-motion study of healthcare providers in Nepal.
Workload in antenatal care before and after implementation of an electronic decision support system: an observed time-motion study of healthcare providers in Nepal.
Fuente:Bmc Medical Informatics and Decision Making
Extracto:
Time spent on ANC and
related recordkeeping was low and did not change after implementation of the
electronic decision support system. ANC and recordkeeping time was sensitive to
day-to-day fluctuations in numbers of women attending for ANC at these rural
facilities, which may have masked the intervention's effects. However, the large
amount of non-work time observed suggests time constraints during the workday
were not a major factor inhibiting use of the electronic decision support system.
Claves:Antenatal care, Auxiliary nurse midwives, Electronic decision support system, Nepal, Time-and-motion study, Workload
Cita:BMC Med Inform Decis Mak 2025 Feb 18; 25 (1) : 87.
Autor/es:Radovich, Emma (a) Das, Seema (b)
institución:(a) Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UK. Emma.radovich@lshtm.ac.uk. (b) Research and Development Division, Dhulikhel Hospital Kathmandu University Hospital, Dhulikhel, Nepal.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
A meta-analysis on the incidence rate of depression in Chinese menopausal women.
A meta-analysis on the incidence rate of depression in Chinese menopausal women.
Fuente:Bmc Psychiatry
Tipo de trabajo:Metanálisis
Extracto:
According to our records, the incidence rate of
depression among Chinese menopausal women was 32%. The summary results indicated
that in China, the incidence rate of depression in menopausal women was
relatively high. It is essential to take notice of the screening of depression in
the menopausal population as soon as possible and actively adopt prevention and
treatment measures for menopausal depression. This has important public health
significance for identifying high-risk groups and patients, and improving
prognosis. META-ANALYSIS REGISTRATION: PROSPERO ( york.ac.uk ), Identifier
CRD42024542320.
Claves:Chinese, Depression, Menopausal women, Meta-analysis, The incidence rate
Cita:BMC Psychiatry 2025 Feb 19; 25 (1) : 154.
Autor/es:Li, Xuan-Ling (a) Lin, Guang-Yao (b)
institución:(a) Department of Gynecology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China. (b) Department of Gynecology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
