Textos Completos Autorizados

Obstetricia y Ginecología
SIIC selecciona textos completos de calidad y de reciente publicación en fuentes prestigiosas del mundo indizadas por SIIC Data Bases, capturadas en las mismas colecciones o en diversas bases especializadas.
La creciente cantidad de artículos con Acceso Abierto (Open Access) amplía la oferta de lectura pero a su vez también, entre tanta abundancia, complica al lector en su encuentro con los estudios fundamentales. Para facilitarlo, profesionales biomédicos de SIIC consultan diariamente una profusa cantidad de documentos que nutrirán Textos completos autorizados (TCA).

Las citas de la sección TCA enlazan de manera legal, autorizada y gratuita con los textos completos (full text) publicados en los sitios oficiales de sus respectivas fuentes.

SIIC creó, produjo y opera con exclusividad el software TCA para la interpretación de los diversos campos documentales que integran la estructura de un estudio: especialidad, modalidad del estudio, fuente, fechas de publicación y selección, definición de la fuente, limitaciones de consulta, resumen en castellano, etc.

Si bien la mayoría de los textos seleccionados corresponden a artículos originales, revisiones y guías, los lectores también encontrarán comentarios, entrevistas, notas periodísticas, cartas a autores u otros textos precursores de debates o aclaratorios.

Con una o todas las palabras
(escribir en inglés)
 
Ej.1: Adipokines Ej.2: Adipokines or Musculoskeletal
Con la frase exacta
(inglés)

Ej.3: Adipokines and Cardiovascular Systems
Con todas de las palabras
(inglés)

Ej.4: Adipokines and Cardiovascular and Systems
Sin las palabras
(inglés)

Ej.5: not Cardiovascular Systems
International journal of environmental research and public health
Selección SIIC: 27 Febrero, 2025
International journal of environmental research and public health

Perception of Risk for Developing Severe Illness or Complications from COVID-19 in Brazil: Focus on Factors Linked to Socially Vulnerable Populations, 2020-2023.

Perception of Risk for Developing Severe Illness or Complications from COVID-19 in Brazil: Focus on Factors Linked to Socially Vulnerable Populations, 2020-2023.

Fuente:International Journal of Environmental Research and Public Health

Extracto: Despite facing greater socioeconomic challenges, vulnerable groups, particularly those experiencing homelessness and slum dwellers, showed a lower perception of the risk for severe COVID-19 complications.

Claves:COVID-19, associated factors, pandemic, risk perception

Cita:Int J Environ Res Public Health 2025 Feb 11; 22 (2)

Autor/es:Rosa, Rander Junior (a)
Ferezin, Letícia Perticarrara (b)

institución:(a) School of Nursing, University of São Paulo at Ribeirão Preto, Ribeirão Preto 14040-902, Brazil.
(b) School of Nursing, University of São Paulo at Ribeirão Preto, Ribeirão Preto 14040-902, Brazil.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijerph22020251

International journal of molecular sciences
Selección SIIC: 27 Febrero, 2025
International journal of molecular sciences

Genomic and Antigenic Differences Between Monkeypox Virus and Vaccinia Vaccines: Insights and Implications for Vaccinology.

Genomic and Antigenic Differences Between Monkeypox Virus and Vaccinia Vaccines: Insights and Implications for Vaccinology.

Fuente:International Journal of Molecular Sciences

Extracto: Phylogenomic analysis, combined with structural modeling and variant profiling, has yielded valuable insights into the virus and vaccine, guiding vaccine design and functional studies.

Claves:bioinformatics, disease outbreaks, monkeypox, monkeypox virus, phylogeny, poxvirus, taxonomic classification, vaccinia virus, virus database

Cita:Int J Mol Sci 2025 Feb 8; 26 (4)

Autor/es:Shen-Gunther, Jane (a)
Cai, Hong (b)

institución:(a) Gynecologic Oncology & Molecular Medicine, Department of Molecular Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
(b) Department of Molecular Microbiology and Immunology, University of Texas at San Antonio, San Antonio, TX 78249, USA.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms26041428

Selección SIIC: 27 Febrero, 2025

Non-Invasive Assessment of Neurogenesis Dysfunction in Fetuses with Early-Onset Growth Restriction Using Fetal Neuronal Exosomes Isolating from Maternal Blood: A Pilot Study.

Non-Invasive Assessment of Neurogenesis Dysfunction in Fetuses with Early-Onset Growth Restriction Using Fetal Neuronal Exosomes Isolating from Maternal Blood: A Pilot Study.

Fuente:International Journal of Molecular Sciences

Extracto: Our study opens up new possibilities for non-invasive prenatal monitoring of fetal neurodevelopment disorders and possibilities of their correction in placenta-associated diseases.

Claves:fetal growth restriction, fetal neuronal exosomes, neddylation, placental dysfunction, sumoylation

Cita:Int J Mol Sci 2025 Feb 11; 26 (4)

Autor/es:Gusar, Vladislava (a)
Kan, Natalia (b)

institución:(a) Laboratory of Applied Transcriptomics, Federal State Budget Institution "National Medical Research Center for Obstetrics, Gynecology and Perinatology Named after Academician V.I. Kulakov" of the Ministry of Health of the Russian Federation, 4, Oparina Street, 117997 Moscow, Russia.
(b) Federal State Budget Institution "National Medical Research Center for Obstetrics, Gynecology and Perinatology Named after Academician V.I. Kulakov" of the Ministry of Health of the Russian Federation, 4, Oparina Street, 117997 Moscow, Russia.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms26041497

Selección SIIC: 27 Febrero, 2025

Variants of the Progesterone Receptor Gene as Modulators of Risk for Idiopathic Spontaneous Premature Birth.

Variants of the Progesterone Receptor Gene as Modulators of Risk for Idiopathic Spontaneous Premature Birth.

Fuente:International Journal of Molecular Sciences

Extracto: Further research on a larger number of subjects of these and other PGR SNPs will be needed in order to confirm the presented results.

Claves:genetic variation, premature birth, progesterone, progesterone receptors, single-nucleotide polymorphisms

Cita:Int J Mol Sci 2025 Feb 13; 26 (4)

Autor/es:Kadivnik, Mirta (a)
Dundović, Marija (b)

institución:(a) Clinic of Obstetrics and Gynecology, University Hospital Center Osijek, J. Huttlera 4, 31000 Osijek, Croatia.
(b) Department of Obstetrics and Gynecology, Faculty of Medicine, J.J. Strossmayer University, 31000 Osijek, Croatia.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms26041606

Selección SIIC: 27 Febrero, 2025

Adiponectin C1Q and Collagen Domain Containing rs266729, Cyclin-Dependent Kinase Inhibitor 2A and 2B rs10811661, and Signal Sequence Receptor Subunit 1 rs9505118 Polymorphisms and Their Association with Gestational Diabetes Mellitus: A Case-Control Study in a Romanian Population.

Adiponectin C1Q and Collagen Domain Containing rs266729, Cyclin-Dependent Kinase Inhibitor 2A and 2B rs10811661, and Signal Sequence Receptor Subunit 1 rs9505118 Polymorphisms and Their Association with Gestational Diabetes Mellitus: A Case-Control Study in a Romanian Population.

Fuente:International Journal of Molecular Sciences

Extracto: Our results suggest that the ADIPOQ rs266729, the CDKN2A/2B rs10811661, and the SSR1 rs9505118 gene polymorphisms are not associated with GDM in a cohort of Romanian pregnant women.

Claves:ADIPOQ, CDKN2A/2B, SNPs, SSR1, gene, gestational diabetes mellitus

Cita:Int J Mol Sci 2025 Feb 14; 26 (4)

Autor/es:Muntean, Mihai (a)
Mărginean, Claudiu (b)

institución:(a) Department of Obstetrics and Gynecology 2, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Târgu Mureș, 540142 Târgu Mureș, Romania.
(b) Department of Obstetrics and Gynecology 2, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Târgu Mureș, 540142 Târgu Mureș, Romania.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms26041654

Selección SIIC: 27 Febrero, 2025

Differential Expression of Small Non-Coding RNAs in Uterine Leiomyomas.

Differential Expression of Small Non-Coding RNAs in Uterine Leiomyomas.

Fuente:International Journal of Molecular Sciences

Extracto: These findings suggest that sncRNA dysregulation contributes to altered gene expression in Lyo, influenced by MED12 mutation and racial background.

Claves:MED12, fibroid, leiomyoma, miRNA, piRNA, race, sncRNA

Cita:Int J Mol Sci 2025 Feb 16; 26 (4)

Autor/es:Chuang, Tsai-Der (a)
Ton, Nhu (b)

institución:(a) The Lundquist Institute for Biomedical Innovation, Torrance, CA 90502, USA.
(b) The Lundquist Institute for Biomedical Innovation, Torrance, CA 90502, USA.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/ijms26041688

Nutrients
Selección SIIC: 27 Febrero, 2025
Nutrients

Association Between Triglyceride-Glucose Related Index and Endometriosis Varies According to Educational Level.

Association Between Triglyceride-Glucose Related Index and Endometriosis Varies According to Educational Level.

Fuente:Nutrients

Extracto: Our study suggests that there is variation in the association between TyG and its obesity-related derivatives and EMS across different educational levels, warranting further investigation. In individuals with higher education, elevated levels of TyG and its obesity-related derivatives were associated with a higher prevalence of EMS. Conversely, this correlation was not observed among those with lower educational levels.

Claves:NHANES, TyG, TyG-BMI, TyG-WC, TyG-WHtR, endometriosis, high educational level

Cita:Nutrients 2025 Feb 13; 17 (4)

Autor/es:Lin, Chuan (a)
Wu, Qian (b)

institución:(a) Department of Biomedical Sciences, Institute for Medical Science, Jeonbuk National University Medical School, Jeonju 501-757, Republic of Korea.
(b) Research Institute of Clinical Medicine, Department of Orthopedics, Jeonbuk National University Medical School, Jeonju 501-757, Republic of Korea.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/nu17040670

Selección SIIC: 27 Febrero, 2025

Association of Oxidative Stress Markers with Incident Hyperglycemia in Gestational Diabetes Mellitus in an Educational Intervention.

Association of Oxidative Stress Markers with Incident Hyperglycemia in Gestational Diabetes Mellitus in an Educational Intervention.

Fuente:Nutrients

Extracto: Higher concentrations of plasma markers of oxidative stress are associated with postpartum incident hyperglycemia in women with gestational diabetes.

Claves:gestational diabetes mellitus, incident hyperglycemia, oxidative stress markers

Cita:Nutrients 2025 Feb 14; 17 (4)

Autor/es:Ruiz-Martínez, Mónica L (a)
Gómez-Díaz, Rita A (b)

institución:(a) Unidad de Investigación Médica en Epidemiología Clínica UMAE HE CMN SXXI, Instituto Mexicano del Seguro Social (IMSS), Av. Cuauhtemoc 330, Mexico City 06720, Mexico.
(b) Unidad de Investigación Médica en Epidemiología Clínica UMAE HE CMN SXXI, Instituto Mexicano del Seguro Social (IMSS), Av. Cuauhtemoc 330, Mexico City 06720, Mexico.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/nu17040680

Medicina (Kaunas, Lithuania)
Selección SIIC: 27 Febrero, 2025
Medicina (Kaunas, Lithuania)

Clinical Analysis of Congenital Duodenal Obstruction and the Role of Annular Pancreas.

Clinical Analysis of Congenital Duodenal Obstruction and the Role of Annular Pancreas.

Fuente:Medicina (kaunas, Lithuania)

Extracto: Given the higher rates of chromosomal abnormalities in cases of annular pancreas, it is clear that more reliable markers or imaging techniques are needed to detect the ethiology of CDO in the prenatal period.

Claves:annular pancreas, chromosomal abnormality, duodenal obstruction, prenatal diagnosis, ultrasound

Cita:Medicina (Kaunas) 2025 Jan 21; 61 (2)

Autor/es:Taşdemir, Ümit (a)
Demirci, Oya (b)

institución:(a) Department of Obstetrics, Division of Perinatology, Zeynep Kamil Women and Children Diseases Training and Research Hospital, İstanbul 34668, Turkey.
(b) Department of Obstetrics, Division of Perinatology, Zeynep Kamil Women and Children Diseases Training and Research Hospital, İstanbul 34668, Turkey.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/medicina61020171

Selección SIIC: 27 Febrero, 2025

Prevalence and Associated Factors of Traction Alopecia in Women in North Sudan: A Community-Based, Cross-Sectional Study.

Prevalence and Associated Factors of Traction Alopecia in Women in North Sudan: A Community-Based, Cross-Sectional Study.

Fuente:Medicina (kaunas, Lithuania)

Extracto: Increasing awareness of this condition, providing education on proper hair care methods, and conducting large-scale research are essential steps to prevent its occurrence.

Claves:age, chemicals, hair care practice, hairstyle, traction alopecia

Cita:Medicina (Kaunas) 2025 Jan 23; 61 (2)

Autor/es:Abdallah, Sama (a)
Hassan, Ahmed A (b)

institución:(a) Department of Dermatology, Qunfudah General Hospital, Qunfudah 28821, Saudi Arabia.
(b) Department of Medicine, Faculty of Medicine, University of Khartoum, Khartoum 11115, Sudan.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/medicina61020195

Selección SIIC: 27 Febrero, 2025

Impact of Smoking on Cervical Histopathological Changes in High-Risk HPV-Positive Women: A Matched Case-Control Study.

Impact of Smoking on Cervical Histopathological Changes in High-Risk HPV-Positive Women: A Matched Case-Control Study.

Fuente:Medicina (kaunas, Lithuania)

Extracto: It is crucial for women to cease smoking in order to eradicate HPV infection from the body.

Claves:cigarettes, colposcopy, endocervical curettage, high-risk HPV, histopathology, quantity of cigarette packs

Cita:Medicina (Kaunas) 2025 Jan 28; 61 (2)

Autor/es:Kayar, İlkan (a)
Goc, Goksu (b)

institución:(a) Department of Obstetrics and Gynecology, Osmaniye State Hospital, 80000 Osmaniye, Turkey.
(b) Department of Obstetrics and Gynecology, American Hospital, 10000 Prishtine, Kosovo.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/medicina61020235

Selección SIIC: 27 Febrero, 2025

Does Magnesium Affect Sex Hormones and Cardiometabolic Risk Factors in Patients with PCOS? Findings from a Systematic Review and Meta-Analysis.

Does Magnesium Affect Sex Hormones and Cardiometabolic Risk Factors in Patients with PCOS? Findings from a Systematic Review and Meta-Analysis.

Fuente:Medicina (kaunas, Lithuania)

Tipo de trabajo:Revisión sistemática

Extracto: PROSPERO database (CRD42024526110).

Claves:cardiometabolic risk factors, magnesium, polycystic ovarian syndrome, sex hormones

Cita:Medicina (Kaunas) 2025 Feb 6; 61 (2)

Autor/es:Abu-Zaid, Ahmed (a)
Alzayed, Mooza M (b)

institución:(a) Department of Biochemistry and Molecular Medicine, Alfaisal University, Riyadh 11533, Saudi Arabia.
(b) College of Medicine and Medical Sciences, Arabian Gulf University, Manama 329, Bahrain.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/medicina61020280

Selección SIIC: 27 Febrero, 2025

Estrogen Treatment Lowers the Risk of Complications in Menopausal Women with Mild Burn Injury.

Estrogen Treatment Lowers the Risk of Complications in Menopausal Women with Mild Burn Injury.

Fuente:Medicina (kaunas, Lithuania)

Extracto: Conclusions: Estrogen treatment decreases the risk probabilities of breast cancer and other complications in postmenopausal women from 3 months to 3 years after mild burn injury.

Claves:average treatment effect (ATE), female hormone treatment, postmenopausal women, retrospective study, thermal injury

Cita:Medicina (Kaunas) 2025 Feb 9; 61 (2)

Autor/es:Song, Juquan (a)
Golovko, George (b)

institución:(a) Department of Surgery, University of Texas Medical Branch, Galveston, TX 77555, USA.
(b) Department of Pharmacology, University of Texas Medical Branch, Galveston, TX 77555, USA.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/medicina61020300

Selección SIIC: 27 Febrero, 2025

The Relationship Between Thrombophilia and Modifications in First-Trimester Prenatal Screening Markers.

The Relationship Between Thrombophilia and Modifications in First-Trimester Prenatal Screening Markers.

Fuente:Medicina (kaunas, Lithuania)

Extracto: These findings emphasize the importance of integrating maternal characteristics into screening protocols to enhance predictive accuracy and maternal-fetal outcomes.

Claves:PAPP-A, first-trimester screening, nuchal translucency, parity, thrombophilic mutations

Cita:Medicina (Kaunas) 2025 Feb 12; 61 (2)

Autor/es:Murvai, Viorela Romina (a)
Radu, Casandra-Maria (b)

institución:(a) Doctoral School of Biological and Biomedical Sciences, University of Oradea, 1 University Street, 410087 Oradea, Romania.
(b) Department of Obstetrics and Gynecology, Emergency County Hospital Bihor, 65 Gheorghe Doja Street, 410169 Oradea, Romania.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/medicina61020318

Selección SIIC: 27 Febrero, 2025

The Role of Medical Therapies in the Management of Cervical Intraepithelial Neoplasia

The Role of Medical Therapies in the Management of Cervical Intraepithelial Neoplasia

Fuente:Medicina (kaunas, Lithuania)

Tipo de trabajo:Revisión

Extracto: Future directions were also sought.

Claves:cervical intraepithelial neoplasia, human papilloma virus, personalized treatment

Cita:Medicina (Kaunas) 2025 Feb 13; 61 (2)

Autor/es:Rotar, Ioana Cristina (a)
Boitor Borza, Dan (b)

institución:(a) Obstetrics and Gynecology I, Mother and Child Department, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.
(b) Obstetrics and Gynecology I, Mother and Child Department, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/medicina61020326

Viruses
Selección SIIC: 27 Febrero, 2025
Viruses

The Angiogenic Markers PlGF and sFlt-1 in Cytomegalovirus Infection During Pregnancy: Insights from a Clinical Case.

The Angiogenic Markers PlGF and sFlt-1 in Cytomegalovirus Infection During Pregnancy: Insights from a Clinical Case.

Fuente:Viruses

Extracto: This case report shows the potential utility of angiogenic markers, such as placental growth factor (PlGF) and soluble fms-like tyrosine kinase-1 (sFlt-1), in assessing CMV-related placental involvement and monitoring the effect of antiviral therapy on placental function, and highlights the possibility of integrating these markers into the clinical management of CMV infection.

Claves:PlGF, angiogenic markers, cytomegalovirus, infection, placental dysfunction, sFlt-1, sFlt-1/PlGF

Cita:Viruses 2025 Feb 15; 17 (2)

Autor/es:Giardini, Valentina (a)
Chiozzi, Ramona (b)

institución:(a) Unit of Obstetrics, Foundation IRCCS San Gerardo dei Tintori, 20900 Monza, Italy.
(b) Specialization School in Obstetrics and Gynecology, University of Milano-Bicocca, 20900 Monza, Italy.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/v17020267

Selección SIIC: 27 Febrero, 2025

Phylogenetic Analysis of Varicella-Zoster Virus in Cerebrospinal Fluid from Individuals with Acute Central Nervous System Infection: An Exploratory Study.

Phylogenetic Analysis of Varicella-Zoster Virus in Cerebrospinal Fluid from Individuals with Acute Central Nervous System Infection: An Exploratory Study.

Fuente:Viruses

Extracto: Enhanced characterization of circulating Varicella-Zoster virus Clades in Brazil identified previously unreported Clades 2 and 6 as well as three other Clades disseminated intercontinentally. These findings reinforce the importance of Varicella-Zoster virus molecular surveillance in cerebrospinal fluid.

Claves:Clade variation, Varicella–Zoster virus, central nervous system

Cita:Viruses 2025 Feb 19; 17 (2)

Autor/es:Paião, Heuder G O (a)
da Costa, Antônio C (b)

institución:(a) Laboratório de Virologia (LIM52), Instituto de Medicina Tropical de São Paulo, Faculdade de Medicina da Universidade de São Paulo, Av. Dr Enéas de Carvalho Aguiar, 470, São Paulo 05403-000, Brazil.
(b) Departamento de Infectologia e Medicina Tropical, Faculdade de Medicina da Universidade de São Paulo, Av. Dr Arnaldo, 455, São Paulo 01246-903, Brazil.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3390/v17020286

Cancer medicine
Selección SIIC: 27 Febrero, 2025
Cancer medicine

Acceptability of Home-Based Urine Self-Collection for Cervical Cancer Screening Among Women Receiving Care at the Arab Community Center for Economic and Social Services in Michigan.

Acceptability of Home-Based Urine Self-Collection for Cervical Cancer Screening Among Women Receiving Care at the Arab Community Center for Economic and Social Services in Michigan.

Fuente:Cancer Medicine

Extracto: MENA participants in this study positively received home-based cervical cancer screening using urine HPV self-sampling kits. These findings support the clinical implementation of self-sampling and home-based cervical cancer screening to increase participation, particularly among those in under-screened communities.

Claves:Middle Eastern‐North African (MENA), cervical cancer screening, qualitative study, self‐sampling

Cita:Cancer Med 2025 Feb; 14 (4) : e70714.

Autor/es:Guetterman, Timothy C (a)
El Khoury, Christelle (b)

institución:(a) Department of Family Medicine, University of Michigan, Ann Arbor, Michigan, USA.
(b) Department of Family Medicine, University of Michigan, Ann Arbor, Michigan, USA.

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1002/cam4.70714

Cadernos de saude publica
Selección SIIC: 27 Febrero, 2025
Cadernos de saude publica

[Births in Brazilian Birthing Centers: a research protocol].

[Births in Brazilian Birthing Centers: a research protocol].

Fuente:Cadernos de Saude Publica

Extracto: Study variables and instruments, the stages of data collection from admission up to 120 days after childbirth, the research team's activities, the data analysis plan, and the ethical aspects are shown and the relevance of disseminating this research protocol and the specificities of research in Birthing Centers are discussed.

Cita:Cad Saude Publica 2025; 41 (1) : e00233023.

Autor/es:Leister, Nathalie (a)
Bussadori, Jamile Claro de Castro (b)

institución:(a) City St. George's, University of London, London, U.K.
(b) Escola de Enfermagem, Universidade de São Paulo, São Paulo, Brasil.

Formato:Informe virtual

Idioma:por

País de fuente:Brasil

Sitio web:http://dx.doi.org/10.1590/0102-311XPT233023

JAMA network open
Selección SIIC: 27 Febrero, 2025
JAMA network open

Genetic Alterations, Therapy Response, and Survival Among Patients With Triple-Negative Breast Cancer

Genetic Alterations, Therapy Response, and Survival Among Patients With Triple-Negative Breast Cancer

Fuente:Jama Network Open

Tipo de trabajo:Estudio clínico aleatorizado

Extracto: AND RELEVANCE: In this secondary analysis of the WSG-ADAPT-TN randomized clinical trial on tPVs, deescalated nab-paclitaxel plus carboplatin was superior to nab-paclitaxel plus gemcitabine, particularly in patients with BRCA1 and/or BRCA2 tPVs. These findings suggest that BRCA1 and/or BRCA2 tPV status could be a candidate marker for a deescalation strategy in early-stage TNBC; however, prospective validation of survival outcomes in larger cohorts with differentiation between germline and somatic pathogenic variants is necessary. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT01815242.

Cita:JAMA Netw Open 2025 Feb 3; 8 (2) : e2461639.

Autor/es:Richters, Lisa (a)
Gluz, Oleg (b)

institución:(a) Center for Familial Breast and Ovarian Cancer, Faculty of Medicine, University Hospital Cologne, Cologne, Germany.
(b) Center for Integrated Oncology, Faculty of Medicine, University Hospital Cologne, Cologne, Germany.

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1001/jamanetworkopen.2024.61639

1 2 3 4 5 6 7 8  9 10 11 12 13 14 15 16 17 18 19 20 Avanza 20 páginas
Inicio/Home

Copyright siicsalud © 1997-2025 ISSN siicsalud: 1667-9008