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SIIC created, produced and handles the AFT software that deciphers
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Association between factor I fibrinogen (rs6050) and factor XI plasma thromboplastin (rs4253417) genetic polymorphisms and recurrent spontaneous miscarriage in Saudi women.
Association between factor I fibrinogen (rs6050) and factor XI plasma thromboplastin (rs4253417) genetic polymorphisms and recurrent spontaneous miscarriage in Saudi women.
Fuente:Saudi Medical Journal
Extracto:
We demonstrated a significant correlation
between genetic polymorphisms in factor I fibrinogen in certain genes studied and
RSM. This association could be attributed to changes in fibrinogen levels, which
impact the coagulation process and lead to an increase in thrombotic events,
which are recognized as risk factors for miscarriage. Notably, variations in the
other genes examined did not exhibit any association with the risk of RSM.
Claves:Recurrent spontaneous miscarriage, Single-nucleotide polymorphisms (SNPs), TaqMan assay, clotting factors, factor I fibrinogen, factor XI plasma thromboplastin, genomic DNA
Cita:Saudi Med J 2025 Feb; 46 (2) : 150-156.
Autor/es:Kaabi, Aaishah M (a) Alkhuriji, Afrah F (b)
institución:(a) From the Department of Zoology (Aaishah Kaabi, Al-Khuriji), College of Science; from the Department of Obstetrics and Gynecology (Babay)King Saud University; from the Central Military Laboratory & Blood Bank (Abdullah Kaabi), Prince Sultan Military Medical City, Riyadh; and from the Department of Laboratory and Blood Bank (Reem Kaabi), Al-Bukayriyah General Hospital, Qassim, Kingdom Saudi Arabia; and from the Cell Biology Department (Barakat), National Research Center, Giza, Egypt. (b) From the Department of Zoology (Aaishah Kaabi, Al-Khuriji), College of Science; from the Department of Obstetrics and Gynecology (Babay)King Saud University; from the Central Military Laboratory & Blood Bank (Abdullah Kaabi), Prince Sultan Military Medical City, Riyadh; and from the Department of Laboratory and Blood Bank (Reem Kaabi), Al-Bukayriyah General Hospital, Qassim, Kingdom Saudi Arabia; and from the Cell Biology Department (Barakat), National Research Center, Giza, Egypt.
institución:(a) Obstetrics and Gynecology, Universitas Airlangga, Faculty of Medicine, Surabaya, East Java, Indonesia. (b) Obstetrics and Gynecology, Universitas Airlangga, Faculty of Medicine, Surabaya, East Java, Indonesia brahmanaaskandar@fk.unair.ac.id.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Spectrochemical differentiation in endometriosis based on infrared spectroscopy advanced data fusion and multivariate analysis.
Spectrochemical differentiation in endometriosis based on infrared spectroscopy advanced data fusion and multivariate analysis.
Fuente:Scientific Reports
Extracto:
To the best
of our knowledge, this is the first study demonstrating the efficacy of a new
tool for fast and non-invasive diagnosis of endometriosis using blood plasma
samples analyzed with IR spectroscopy combined with multivariate classification.
Claves:Blood plasm, Chemometrics, Data fusion, Endometriosis, Spectroscopy
institución:(a) Graduate Program in Science Applied to Women's Health, Federal University of Rio Grande Do Norte, Natal, RN, 59012-310, Brazil. (b) Biological Chemistry and Chemometrics, Institute of Chemistry, Federal University of Rio Grande Do Norte, Natal, RN, 5072-970, Brazil.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Extracto:
Tissue infarction in patients with brucellosis can impact various
organs, particularly the brain, spleen, and heart, with symptoms differing based
on the specific organ involved. As patients with brucellosis exhibit symptoms of
tissue infarction, healthcare providers should be aware of this complication.
Prompt diagnosis can be achieved through laboratory and imaging investigations.
Appropriate medical and surgical treatments should be provided for these cases.
TRIAL REGISTRATION: The study protocol was registered in the international
prospective registry of systematic reviews known as PROSPERO (Protocol number:
CRD42024595263).
institución:(a) Infectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Amirrezakeyvanfar@yahoo.com. (b) Preventative Gynecology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
A nomogram for predicting the risk of fetal growth restriction in singleton pregnancies with subchorionic hematomas detected in first trimester.
A nomogram for predicting the risk of fetal growth restriction in singleton pregnancies with subchorionic hematomas detected in first trimester.
Fuente:Bmc Pregnancy and Childbirth
Tipo de trabajo:Estudio de cohortes
Extracto:
First trimester SCH is independently associated with an
increased risk of FGR, and the nomogram developed effectively predicts FGR in
pregnancies with SCH.
Depression, anxiety, and stress among HIV-positive pregnant women during the COVID-19 pandemic: a hospital-based cross-sectional study in India.
Depression, anxiety, and stress among HIV-positive pregnant women during the COVID-19 pandemic: a hospital-based cross-sectional study in India.
Fuente:Bmc Pregnancy and Childbirth
Extracto:
The study concludes that about
one-third of the HIV-positive pregnant women reported anxiety, and more than half
of the women were feeling stressed and depressed during COVID-19. Factors such as
residence and primigravidae were linked with antenatal depression. Whereas
variables like ANC visits, knowing HIV status during pregnancy, non-disclosure of
HIV status, no partner's support, and sexual partner HIV negative status were
associated with depression and stress. The anxiety symptoms are very high among
women who are HIV positive during pregnancy, and not having a partner's support.
Demographic, clinical, and support-related determinants and COVID-19 stressors of
DAS provide insights for interventions to reduce the burden of mental health
problems among HIV-positive pregnant women.
Claves:Antenatal, Anxiety, Depression, HIV, India, Mental health, Pregnant women, Stress
Cita:BMC Pregnancy Childbirth 2025 Feb 11; 25 (1) : 134.
institución:(a) Department of Clinical Pharmacy, College of Pharmacy, Kingdom of Saudi Arabia, King Khalid University, Abha, 61421, Kingdom of Saudi Arabia. (b) Department of Clinical Pharmacy, College of Pharmacy, Kingdom of Saudi Arabia, King Khalid University, Abha, 61421, Kingdom of Saudi Arabia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
A rapid and effective approach to building a life-saving multidisciplinary team for transferred postpartum haemorrhage patients: leveraging trauma experience-a retrospective study.
A rapid and effective approach to building a life-saving multidisciplinary team for transferred postpartum haemorrhage patients: leveraging trauma experience-a retrospective study.
Fuente:Bmc Pregnancy and Childbirth
Tipo de trabajo:Estudio de cohortes
Extracto:
Leveraging trauma team expertise is an
effective strategy for establishing a multidisciplinary PPH team, significantly
improving outcomes for critically ill PPH patients transferred from obstetric
clinics.
Claves:Blood transfusion, Multidisciplinary team, Patient transfer, Postpartum haemorrhage, Team training, Trauma team
Cita:BMC Pregnancy Childbirth 2025 Feb 11; 25 (1) : 137.
Autor/es:Yu, Pei-Hsiu (a) Hung, Kuo-Shu (b)
institución:(a) Department of Obstetrics and Gynecology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. (b) Department of Obstetrics and Gynecology, AnAn Women and Children Clinic, Tainan, Taiwan.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Machine learning approaches for predicting fetal macrosomia at different stages of pregnancy: a retrospective study in China.
Machine learning approaches for predicting fetal macrosomia at different stages of pregnancy: a retrospective study in China.
Fuente:Bmc Pregnancy and Childbirth
Extracto:
This is the first study to
utilize machine learning with data from the pre-pregnancy, first-trimester, and
pre-labor periods to predict macrosomia. The logistic regression model and the
final ensemble model demonstrated strong predictive performance, offering
valuable insights to improve pre-pregnancy counseling, antenatal assessment, and
intrapartum decision-making.
Cita:BMC Pregnancy Childbirth 2025 Feb 11; 25 (1) : 140.
Autor/es:Liu, Qingyuan (a) Zhu, Simin (b)
institución:(a) Department of Obstetrics and Gynecology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China. (b) School of Medicine, Tsinghua Medicine, Tsinghua University, Beijing, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
The effect of hrHPV prevalence on cervical cancer screening strategies: a cost-effectiveness study of Bangladesh.
The effect of hrHPV prevalence on cervical cancer screening strategies: a cost-effectiveness study of Bangladesh.
Fuente:Bmc Public Health
Extracto:
Our study demonstrates that
the hrHPV test + VIA strategy is cost-effective both compared to no screening and
VIA + colposcopy screening strategy under the optimal (70%) and realistic (8.7%)
uptake scenarios, with greater cost-effectiveness at higher hrHPV prevalence
levels. While VIA-based strategy is cheaper, self-sampling hrHPV test-based
strategy offers greater health benefits. Implementing hrHPV testing in national
screening programs at lower hrHPV test prices is crucial for promoting health
equity and accelerating cervical cancer elimination worldwide. In
resource-constrained settings, screening with hrHPV testing should initially
target high-prevalence populations.
Claves:Bangladesh, Cost-effectiveness analysis, Human papillomavirus DNA tests, Prevalence
Cita:BMC Public Health 2025 Feb 11; 25 (1) : 561.
Autor/es:Pan, Fengming (a) van der Schans, Jurjen (b)
institución:(a) Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. f.pan@umcg.nl. (b) Unit of Global Health, Department of Health Sciences, University Medical Center Groningen, Groningen, The Netherlands.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Duration of the second and third stages of labor and risk of postpartum hemorrhage
Duration of the second and third stages of labor and risk of postpartum hemorrhage
Fuente:Bmc Pregnancy and Childbirth
Tipo de trabajo:Estudio de cohortes
Extracto:
The duration of
oxytocin exposure was found to be a risk factor for PPH among nulliparous women
as was a history of PPH among parous women. Future studies should focus on
duration of third stage of labor, especially when active management of the third
stage of labor (AMTSL) is routinely used. TRIAL REGISTRATION: The trial was
registered at ClinicalTrials.gov NCT01113229.
Claves:Parity, Postpartum hemorrhage, Risk factors, Stage of labor
Cita:BMC Pregnancy Childbirth 2025 Feb 11; 25 (1) : 143.
Autor/es:Voillequin, Sandrine (a) Quibel, T (b)
institución:(a) Paris Saclay University, UVSQ, CESP, Inserm, Villejuif, 94805, France. voillequin.sandrine@gmail.com. (b) CHRU Strasbourg, Strasbourg, F-67091, France. voillequin.sandrine@gmail.com.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
The conditions that patients with systemic lupus erythematosus should fulfill before pregnancy to optimize outcomes
The conditions that patients with systemic lupus erythematosus should fulfill before pregnancy to optimize outcomes
Fuente:Arthritis Research & Therapy
Tipo de trabajo:Estudio de cohortes
Extracto:
This study delineated the conditions that patients
with SLE should fulfill before pregnancy, which provides better instructions for
clinical practice.
institución:(a) Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China. (b) Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Identification of WDR74 and TNFRSF12A as biomarkers for early osteoarthritis using machine learning and immunohistochemistry.
Identification of WDR74 and TNFRSF12A as biomarkers for early osteoarthritis using machine learning and immunohistochemistry.
Fuente:Frontiers in Immunology
Extracto:
WDR74 and TNFRSF12A as principal biomarkers highlighted their
attractiveness as therapeutic targets. The identification of core biomarkers
might facilitate early intervention options, potentially modifying the illness
trajectory and enhancing patient outcomes.
institución:(a) Department of Orthopedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. (b) Institute of Microsurgery on Extremities, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Evaluation of the feasibility, acceptability, and impact of Group Antenatal Care at the health post level on continuation in antenatal care and facility based delivery in Ethiopia using a cluster randomized stepped-wedge design: Study protocol.
Evaluation of the feasibility, acceptability, and impact of Group Antenatal Care at the health post level on continuation in antenatal care and facility based delivery in Ethiopia using a cluster randomized stepped-wedge design: Study protocol.
Fuente:Gates Open Research
Extracto:
The study will inform decision makers locally and globally on
whether G-ANC is a feasible service delivery model at the health post level.
Effectiveness of G-ANC at increasing ANC retention and facility-based delivery
will be reported, as well as its acceptability to pregnant women and Health
Extension Workers. REGISTRATION: NCT05054491, ClinicalTrials.gov (September 23
(rd) 2021).
Claves:Ethiopia, Health post, antenatal care, facility-based delivery, group antenatal care, health extension worker, maternal outcomes, rural
Cita:Gates Open Res 2024; 8 : 29.
Autor/es:Yallew, Walelegn W (a) Fasil, Rediet (b)
institución:(a) Addis Continental Institute of Public Health, Addis Ababa, Ethiopia. (b) Addis Continental Institute of Public Health, Addis Ababa, Ethiopia.
[Assessment of birth registration coverage in the Hospital Information System of the Brazilian Unified National Health System, by hospital of admission, Brazil, 2012-2020].
[Assessment of birth registration coverage in the Hospital Information System of the Brazilian Unified National Health System, by hospital of admission, Brazil, 2012-2020].
Fuente:Cadernos de Saude Publica
Extracto:
Strategies for continuous
improvement of quality for information system records are necessary.
Cita:Cad Saude Publica 2025; 40 (12) : e00225623.
Autor/es:Marques, Juliana Alves (a) Domingues, Rosa Maria Soares Madeira (b)
institución:(a) Programa de Pós-graduação em Gestão Urbana, Pontifícia Universidade Católica do Paraná, Londrina, Brasil. (b) Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, Brasil.
Socioeconomic, demographic and obstetric determinants of maternal near miss in Africa
Socioeconomic, demographic and obstetric determinants of maternal near miss in Africa
Fuente:Plos One
Tipo de trabajo:Revisión sistemática
Extracto:
Several
factors, including education, prenatal care follow-up, pre-existing medical
conditions, method of admission, and mode of delivery, have been identified as
significant indicators of the likelihood of severe maternal morbidity. To reduce
these cases, it is crucial to implement targeted socio-economic development
programs, including improving access to education, strengthening prenatal health
services, providing support to pregnant women with pre-existing medical
conditions, and ensuring appropriate admission and delivery methods.
Cita:PLoS One 2025; 20 (2) : e0313897.
Autor/es:Diakite, Mory (a) de Brouwere, Vincent (b)
institución:(a) Kankan Regional Hospital, Kankan, Guinea. (b) Mohammed VI International School of Public Health, Mohammed VI University of Sciences and Health, Casablanca, Morocco.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Identifying risk factors for cancer-specific early death in patients with advanced endometrial cancer: A preliminary predictive model based on SEER data.
Identifying risk factors for cancer-specific early death in patients with advanced endometrial cancer: A preliminary predictive model based on SEER data.
Fuente:Plos One
Extracto:
This study identified key risk factors for early cancer-specific
mortality in patients with advanced endometrial cancer. The preliminary nomogram
model holds promise for predicting early death risk and could be valuable in
clinical practice. Future work may explore its performance with additional data
to ensure broad applicability.
Cita:PLoS One 2025; 20 (2) : e0318632.
Autor/es:Yang, Jing (a) Tian, Qi (b)
institución:(a) Department of Obstetrics and Gynecology, Hunan Provincial Maternal and Child Health Care Hospital, Changsha, Hunan, P.R. China. (b) Department of Obstetrics and Gynecology, Hunan Provincial Maternal and Child Health Care Hospital, Changsha, Hunan, P.R. China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Equitable access to quality trauma systems in Ghana: a qualitative study.
Equitable access to quality trauma systems in Ghana: a qualitative study.
Fuente:Bmj Open
Extracto:
This study shows that multiple factors cause an
injured patient to delay in seeking care, reaching care, receiving care and
remaining in care. Therefore, there is a pressing need for comprehensive,
community-driven strategies to strengthen health literacy at the community level.
There is also a need for facility-based strategies that would improve the
availability of medical and human resources to augment access to quality trauma
care. Additionally, if policymakers focus on removing financial barriers to
trauma care and strengthening referral systems, especially in the remote and
rural areas, it would greatly improve access to quality trauma care in Ghana.
Claves:Health Equity, Health Services Accessibility, PUBLIC HEALTH, TRAUMA MANAGEMENT
Cita:BMJ Open 2025 Feb 12; 15 (2) : e087095.
Autor/es:Kunfah, Sheba Mary Pognaa (a) Yakubu, Mustapha (b)
institución:(a) Department of Public Health, Tamale Teaching Hospital, Tamale, Northern Region, Ghana shebawondoh@gmail.com. (b) School of Medicine and Health Sciences, University for Development Studies School of Medicine, Tamale, Northern Region, Ghana.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
A questionnaire survey of cervical and breast cancer screening among female employees and employees' spouses.
A questionnaire survey of cervical and breast cancer screening among female employees and employees' spouses.
Fuente:Scientific Reports
Extracto:
is unclear.
Claves:Breast cancer screening, Cervical cancer screening, Japan, Occupational health checkup, Quality control assessment of cancer screenings
Cita:Sci Rep 2025 Feb 12; 15 (1) : 5277.
Autor/es:Yagi, Asami (a) Ueda, Yutaka (b)
institución:(a) Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Yamadaoka, Suita, 565-0871, Osaka, Japan. (b) Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Yamadaoka, Suita, 565-0871, Osaka, Japan. ZVF03563@nifty.ne.jp.
Conflicto:Declarations. Conflict of interest: AY, YU, SI, EO, MK, SN, and KH do not have any competing interests to declare. KK, RO, NY, SK, and YT are employees of Sunstar, Inc. Financial support: A Health and Labour Sciences Research Grant (23EA1002) from the MHLW supported this research.
institución:(a) Division of Hematology-Oncology, Department of Internal Medicine, Korea University College of Medicine, Seoul, Republic of Korea. (b) School of Mechanical Engineering, Korea University, Seoul, Republic of Korea.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Changes of diamine oxidase and D-lactate in human breast and gynecologic cancers after chemotherapy.
Changes of diamine oxidase and D-lactate in human breast and gynecologic cancers after chemotherapy.
Fuente:Medicine
Extracto:
Monitoring serum levels of DAO and
D-lactate in cancer patients undergoing chemotherapy can serve as indicators for
evaluating gastrointestinal dysfunction and nutritional status.
Cita:Medicine (Baltimore) 2025 Feb 7; 104 (6) : e41442.
Autor/es:Hu, Lixia (a) Kong, Fanliang (b)
institución:Hu, Lixia (a) Kong, Fanliang (b)
Conflicto:The authors have no financial or personal conflicts of interest related to this work.