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La creciente cantidad de artículos con Acceso Abierto (Open
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gratuita con los textos completos (full text) publicados en
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SIIC creó, produjo y opera con exclusividad el software TCA para la
interpretación de los diversos campos documentales que integran la
estructura de un estudio: especialidad, modalidad del estudio,
fuente, fechas de publicación y selección, definición de la fuente,
limitaciones de consulta, resumen en castellano, etc.
Si bien la mayoría de los textos seleccionados corresponden a
artículos originales, revisiones y guías, los lectores también
encontrarán comentarios, entrevistas, notas periodísticas, cartas a
autores u otros textos precursores de debates o aclaratorios.
Sociedad Iberoamericana de Información Científica (SIIC) selects
complete quality-full texts which have been recently published in
renowned sources worldwide and are indexed by SIIC Data
Bases.
The increasing number of Open Access articles widens the reading offer
but, also, such myriad complicates the readers search of fundamental
articles. To facilitate this, SIIC biomedical professionals daily
consult a profuse amount of documents that will feed
Authorized Full Texts (TCA, Spanish acronym).
The citations of the AFT section link legally, authorized and free of
charge with the full texts published in the official web sites of
their corresponding sources.
SIIC created, produced and handles the AFT software that deciphers
the various documentary fields that form part of the structure of a
study: specialty, study style, source, publication and selection
dates, source definition, query limitations, summary in Spanish,
etc.
While most of the selected texts belong to original articles,
reviews, and guidelines, readers will also find commentaries,
interviews, journalistic reports, letters to authors or other texts
that may lead to discussions or clarifications.
Plasma pQTL and brain eQTL integration identifies PNKP as a therapeutic target and reveals mechanistic insights into migraine pathophysiology.
Plasma pQTL and brain eQTL integration identifies PNKP as a therapeutic target and reveals mechanistic insights into migraine pathophysiology.
Fuente:The Journal of Headache and Pain
Extracto:
PNKP and
MRVI1 exhibit dual mechanisms of action at the gene and protein levels,
potentially involving distinct mechanistic pathways. Among them, PNKP emerges as
a promising drug target for migraine treatment, supported by multi-layered
validation.
institución:(a) Department of Radiology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China. (b) The First School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Association of exposure to air pollutants and risk of mortality among people living with HIV
Association of exposure to air pollutants and risk of mortality among people living with HIV
Fuente:Bmc Public Health
Tipo de trabajo:Revisión sistemática
Extracto:
Air pollution, especially fine
particulate matter and ozone, is associated with a higher risk of mortality in
PLWH. Targeted interventions to reduce pollution exposure in vulnerable subgroups
are crucial. Further research is needed to confirm these findings in diverse
regions and develop effective mitigation strategies.
Claves:Air pollution, Mortality, Nitrogen dioxide, Particulate matter, People living with HIV
Cita:BMC Public Health 2024 Nov 22; 24 (1) : 3251.
institución:(a) Department of Community Medicine, School of Public Health, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India. (b) Division of Evidence Synthesis, Global Consortium of Public Health and Research, Datta Meghe Institute of Higher Education, Wardha, India.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Factors associated with the survival of oral cavity cancer patients: a single institution experience from Karachi, Pakistan.
Factors associated with the survival of oral cavity cancer patients: a single institution experience from Karachi, Pakistan.
Fuente:Bmc Oral Health
Tipo de trabajo:Estudio de cohortes
Extracto:
Notably, there was a high occurrence of late stage (III and
IV) OCC in individuals aged ≤ 50 years, with the buccal mucosa being the most
common site involved. Moreover, a large proportion of our patients had a history
of tobacco use. Patients with advanced-stage disease and poorly differentiated
grade showed poor survival. Therefore, public awareness about tobacco control for
OCC prevention and earlier diagnosis of OCC is urgently needed in our Pakistani
population.
Claves:Oral cavity cancer, Pakistan, Prognosis, Survival, Tobacco use
Cita:BMC Oral Health 2024 Nov 22; 24 (1) : 1427.
Autor/es:Shamsi, Uzma (a) Khan, Muhammad Ali Akbar (b)
institución:(a) Department of Community Health Sciences, Aga Khan University, Karachi, 74800, Pakistan. uzma.shamsi@aku.edu. (b) Medical College, Aga Khan University, Karachi, 74800, Pakistan.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Relevant factors for policy concerning comprehensive genomic profiling in oncology: stakeholder perspectives.
Relevant factors for policy concerning comprehensive genomic profiling in oncology: stakeholder perspectives.
Fuente:Bmc Cancer
Extracto:
Stakeholders deemed "wider implications of diagnostic results", "feasibility",
and "test journey" the most important considerations for decision-making about
targeted profiling vs. CGP alongside clinical benefit and costs. For policy
decision-making, it is important to understand the arguments behind the
heterogeneous opinions, often related to the setting they originate from.
Claves:Comprehensive genomic profiling, Health technology assessment, Next-generation sequencing, Personalized medicine, Precision oncology, Value
Cita:BMC Cancer 2024 Nov 22; 24 (1) : 1441.
Autor/es:van Schaik, Lucas Frederik (a) Engelhardt, Ellen Gurumay (b)
institución:(a) Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute, P.O. Box 90203, Amsterdam, 1006 BE, The Netherlands. (b) Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute, P.O. Box 90203, Amsterdam, 1006 BE, The Netherlands.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Polydopamine(PDA)-coated diselenide-bridged mesoporous silica-based nanoplatform for neuroprotection by reducing oxidative stress and targeting neuroinflammation in intracerebral hemorrhage.
Polydopamine(PDA)-coated diselenide-bridged mesoporous silica-based nanoplatform for neuroprotection by reducing oxidative stress and targeting neuroinflammation in intracerebral hemorrhage.
Fuente:Journal of Nanobiotechnology
Extracto:
Taking together, the synergistic
effect of ROS-responsive drug delivery ability and ROS scavenging ability of
PDA-DSeMSN makes it a powerful drug delivery platform and provided new
considerations into the therapeutic action to improve ICH-induce brain injury.
Cita:J Nanobiotechnology 2024 Nov 23; 22 (1) : 731.
Autor/es:Zhou, Fangfang (a) He, Yongju (b)
institución:(a) Department of Neurology, The Second Xiangya Hospital of Central South University, Changsha, 410011, Hunan, China. (b) Clinical Medical Research Center for Stroke Prevention and Treatment of Hunan Province, Department of Neurology, The Second Xiangya Hospital of Central South University, Changsha, 410011, Hunan, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Rectal cancer with situs inversus totalis and previous malignant middle cerebral artery infarction
Rectal cancer with situs inversus totalis and previous malignant middle cerebral artery infarction
Fuente:Journal of Medical Case Reports
Tipo de trabajo:Revisión
Extracto:
We conclude that patients with
rectal cancer with situs inversus totalis, even when accompanied by underlying
diseases, can undergo surgical treatment with adequate preparation, and surgical
treatment is the most effective treatment method.
institución:(a) Department of Colorectal Surgery, People's Hospital of Rizhao City, Rizhao, 276800, Shandong, China. (b) Department of Colorectal Surgery, People's Hospital of Rizhao City, Rizhao, 276800, Shandong, China.
Conflicto:Declarations. Ethical approval and consent to participate: Not applicable. Consent for publication: All authors of the manuscript have read and agreed to its content and are accountable for all aspects of the accuracy and integrity of the manuscript in accordance with ICMJE criteria; and that the article is original, has not already been published in a journal, and is not...
currently under consideration by another journal. Written informed consent was obtained from the patient for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal. Competing interests: No competing interests.
Exploring determinants of vaccination status among pediatric populations in East Gojam, Amhara Region, Ethiopia.
Exploring determinants of vaccination status among pediatric populations in East Gojam, Amhara Region, Ethiopia.
Fuente:Bmc Pediatrics
Extracto:
This study concludes that addressing these
multifaceted determinants through educational programs, improved healthcare
access, trust-building initiatives, accurate information dissemination, stronger
governmental support, targeted outreach for older children, community engagement,
and multisectoral collaboration can enhance vaccination coverage and improve
public health outcomes in East Gojam and similar settings.
Claves:Cultural beliefs, Ethiopia, Health services accessibility, Multinomial logistic regression, Parental education, Pediatric populations, Sociodemographic factors, Trust in healthcare providers, Vaccination
institución:(a) Department of Statistics, Debremarkos University, Debremarkos, Ethiopia. fetahi.aw@gmail.com. (b) Department of Statistics, Debremarkos University, Debremarkos, Ethiopia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Electrical impedance tomography guided positive end-expiratory pressure titration in critically ill and surgical adult patients
Electrical impedance tomography guided positive end-expiratory pressure titration in critically ill and surgical adult patients
Fuente:Bmc Pulmonary Medicine
Tipo de trabajo:Revisión sistemática
Extracto:
The EIT-derived PEEP setting strategy might be associated
with potential benefits in respiratory outcomes and prognosis in ARDS/hARF and
surgical patients. Current data is insufficient to provide solid evidence.
institución:(a) State Key Laboratory of Complex Severe and Rare Diseases, Department of Critical Care Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China. (b) State Key Laboratory of Complex Severe and Rare Diseases, Department of Critical Care Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China. tjmuhhw@126.com.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Participatory research approaches in long-term care facilities for older adults: a meta-ethnography.
Participatory research approaches in long-term care facilities for older adults: a meta-ethnography.
Fuente:International Journal of Qualitative Studies On Health and Well-being
Tipo de trabajo:Revisión
Extracto:
This meta-ethnography contributes a novel conceptualization and six
recommendations to enhance the design and implementation of participatory
research approaches as democratic spaces of exchange and collaboration for older
adults.
Cita:Int J Qual Stud Health Well-being 2024 Dec; 19 (1) : 2431449.
Autor/es:Gaber, Sophie Nadia (a) Guerrero, Manuel (b)
institución:(a) Department of Neurobiology, Care Sciences and Society, Division of Occupational Therapy, Karolinska Institutet, Stockholm, Sweden. (b) Department of Rehabilitation, School of Health and Welfare, Jönköping University, Jönköping, Sweden.
Conflicto:No potential conflict of interest was reported by the author(s).
Global incidence of osteonecrosis of the femoral head after femoral neck fracture surgery in adolescents
Global incidence of osteonecrosis of the femoral head after femoral neck fracture surgery in adolescents
Fuente:Journal of Orthopaedic Surgery and Research
Tipo de trabajo:Metanálisis
Extracto:
This study revealed that the incidence of ONFH after FNFs in adolescents is high
(24.02%). Early screening and effective treatment of postoperative patients are
crucial.
Claves:Adolescents, Femoral neck fracture, Incidence, Meta-analysis, Osteonecrosis of the femoral head
Cita:J Orthop Surg Res 2024 Nov 24; 19 (1) : 791.
Autor/es:Gu, Bangning (a) Yao, Fangming (b)
institución:(a) The Third School of Clinical Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China. (b) The Third School of Clinical Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Depression, performance status, and discontinued treatment mediate an association of curability belief with prognosis in advanced cancer patients.
Depression, performance status, and discontinued treatment mediate an association of curability belief with prognosis in advanced cancer patients.
Fuente:Scientific Reports
Tipo de trabajo:Estudio clínico
Extracto:
Further research using longitudinal modeling of depression, performance status,
and healthcare utilization, with curability belief and primary tumor site as
covariates, is warranted.Trial registration: Clinical Trial Number
(ClinicalTrials.gov): NCT03222258; Study Registration Dates (First submitted:
2017-06-05; First submitted following the QC criteria: 2017-07-16; First posted:
2017-07-19).
institución:(a) Seoul National University Hospital, Seoul, Republic of Korea. (b) Yeongeon Student Support Center, Seoul National University College of Medicine, Seoul, Republic of Korea.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
IQGAP1 promotes early B cell development, is essential for the development of marginal zone (MZ) B cells, and is critical for both T-dependent and T-independent antibody responses.
IQGAP1 promotes early B cell development, is essential for the development of marginal zone (MZ) B cells, and is critical for both T-dependent and T-independent antibody responses.
Fuente:Cellular and Molecular Life Sciences Cmls
Extracto:
Our study
provides the first evidence that IQGAP1-based signalosome is necessary for the
development and functions of B cells.
Claves:B cell, IQGAP1, IQGAP1 signalosome, MAPK
Cita:Cell Mol Life Sci 2024 Nov 25; 81 (1) : 462.
Autor/es:Lella, Ravi K (a) Malarkannan, Subramaniam (b)
institución:(a) Laboratory of Molecular Immunology and Immunotherapy, Blood Research Institute, Versiti, Milwaukee, WI, USA. (b) Abdi Bio, Abdi Ibrahim Pharmaceuticals, Orhan Gazi Mahallesi Tunc Caddesi No. 3, Esenyurt, Istanbul, Turkey.
Conflicto:Declarations. Conflict of interest: The authors declare that this study was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Ethics approval: All mice used in this study were utilized responsibly, and all protocols were approved by the institutional IACUC committee at the Medical College of Wisconsin (MCW), Milwaukee,...
WI. Author consent: All the authors fully agree to be part of the manuscript and its content. Both authors have participated in collecting, analyzing, and preparing this manuscript.
Therapeutic effect of total glucosides of paeony on IgA vasculitis nephritis: progress and prospects.
Therapeutic effect of total glucosides of paeony on IgA vasculitis nephritis: progress and prospects.
Fuente:Molecular Biology Reports
Extracto:
Additionally, we provide an overview of recent advancements in enhancing the
bioavailability of TGP and highlight crucial considerations that may inform
future research endeavors.
Claves:Bioavailability, IgA vasculitis nephritis, Therapeutic mechanisms, Total glucosides of paeony
Cita:Mol Biol Rep 2024 Nov 25; 52 (1) : 13.
Autor/es:Wang, Zhifeng (a) Yang, Jiao (b)
institución:(a) The First Clinical College of Yunnan University of Chinese Medicine, Kunming, Yunnan, China. (b) The Second Affiliated Hospital of Yunnan University of Chinese Medicine, Kunming, Yunnan, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Improving HIV testing, linkage, and retention in care among South African men through U = U messaging: A study protocol for two sequential hybrid type 1 effectiveness-implementation randomized controlled trials.
Improving HIV testing, linkage, and retention in care among South African men through U = U messaging: A study protocol for two sequential hybrid type 1 effectiveness-implementation randomized controlled trials.
Fuente:Plos One
Tipo de trabajo:Estudio aleatorizado y controlado
Extracto:
If effective, these messaging interventions can
shape global HIV testing, treatment and adherence counselling guidelines and
practices.
Cita:PLoS One 2024; 19 (11) : e0309905.
Autor/es:Medina-Marino, Andrew (a) Sibanda, Nkosiyapha (b)
institución:(a) Desmond Tutu HIV Centre, University of Cape Town, Cape Town, South Africa. (b) Desmond Tutu Health Foundation, Cape Town, South Africa.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Recruitment and Retention Strategies for Historically Marginalized Populations in Colorectal Cancer Trials
Recruitment and Retention Strategies for Historically Marginalized Populations in Colorectal Cancer Trials
Fuente:Journal of Gastrointestinal Cancer
Tipo de trabajo:Revisión sistemática
Extracto:
This study highlights significant gaps in recruitment
and retention strategies for historically marginalized populations in CRC
clinical trials. Few studies implement strategies to address these disparities
which affect the diversity of the trial population, underscoring the need for
targeted efforts to improve trial inclusivity. Addressing these gaps is critical
to ensuring more equitable and representative outcomes in CRC research.
Cita:J Gastrointest Cancer 2024 Nov 26; 56 (1) : 24.
Autor/es:Smith, Harrison (a) Khan, Saad (b)
institución:(a) Office of Medical Student Research, Oklahoma State University Center for Health Sciences, 1111 W 17Th St., Tulsa, OK, 74107, USA. harrison.smith@okstate.edu. (b) Office of Medical Student Research, Oklahoma State University Center for Health Sciences, 1111 W 17Th St., Tulsa, OK, 74107, USA.
Conflicto:Declarations. Ethics Approval: We submitted our protocol to our respective Institutional Review Board (IRB) where it was determined this study did not involve human subjects. Consent to Participate: N/A Consent for Publication: N/A Competing Interests: MV reports receipt of funding from the National Institute on Drug Abuse, the National Institute on Alcohol Abuse and Alcoholism, the U.S. Office of Research...
Integrity, Oklahoma Center for Advancement of Science and Technology, and internal grants from Oklahoma State University Center for Health Sciences — all outside of the present work. AF reports receipt of funding from the Center for Integrative Research on Childhood Adversity, the Oklahoma Shared Clinical and Translational Resources, and internal grants from Oklahoma State University and Oklahoma State University Center for Health Sciences — all outside of the present work. All other authors have nothing to report.
Development of flame retardant slow release insecticides paint and testing its efficacy for four years against dengue and malaria vectors.
Development of flame retardant slow release insecticides paint and testing its efficacy for four years against dengue and malaria vectors.
Fuente:Scientific Reports
Extracto:
In the pretext
of continuous toll of vector borne diseases and trans-boundary expansion of
mosquito vectors into new geographical areas, the idea of using insecticidal
paint could be a game changer.
ParaAntiProt provides paratope prediction using antibody and protein language models.
ParaAntiProt provides paratope prediction using antibody and protein language models.
Fuente:Scientific Reports
Extracto:
These results highlight the potential of our
method to advance disease understanding and aid in the discovery of new
diagnostics and antibody therapies.
Claves:Antibody Language models, Complementarity determining regions, Deep learning, Paratope prediction, Protein Language models
institución:(a) Department of Computer Engineering, Sharif University of Technology, Tehran, Iran. (b) Department of Computer Engineering, Sharif University of Technology, Tehran, Iran.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Nephrology providers' perspective and use of mortality prognostic tools in dialysis patients.
Nephrology providers' perspective and use of mortality prognostic tools in dialysis patients.
Fuente:Bmc Nephrology
Tipo de trabajo:Revisión
Extracto:
Although several well validated
prognostic tools are available for predicting mortality, the nephrology providers
studied do not use them in routine practice, even after an educational
intervention. Other approaches should be explored to help incorporate
prognostication in shared-decision-making for patients receiving dialysis.
Autor/es:Bergeron, Jennifer (a) Marchese, Christina (b)
institución:(a) Division of Nephrology, Department of Medicine, West Virginia University School of Medicine, 1 Medical Center Drive, PO Box 9165, Morgantown, WV, 26506, USA. jennifer.bergeron@hsc.wvu.edu. (b) Division of Nephrology, Department of Medicine, The University of Vermont Medical Center, Burlington, VT, USA. jennifer.bergeron@hsc.wvu.edu.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Sexually dimorphic response to tobacco in the development of chronic kidney disease
Sexually dimorphic response to tobacco in the development of chronic kidney disease
Fuente:Bmc Nephrology
Tipo de trabajo:Revisión sistemática
Extracto:
The findings emphasize the need for further research to comprehend the intricate
relationship between, tobacco exposure, sex, and CKD management, as well as the
consideration of cultural, geographical, socioeconomic, political, and structural
factors when understanding the pathophysiology and management of CKD.
