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The increasing number of Open Access articles widens the reading offer
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SIIC created, produced and handles the AFT software that deciphers
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While most of the selected texts belong to original articles,
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CXCL14 in prostate cancer: complex interactions in the tumor microenvironment and future prospects.
CXCL14 in prostate cancer: complex interactions in the tumor microenvironment and future prospects.
Fuente:Journal of Translational Medicine
Extracto:
Therefore,
this article aims to discuss the role of CXCL14 in the tumor microenvironment of
prostate cancer and explore future research directions and potential
applications.
institución:(a) Department of Urology, Dushu Lake Hospital Affiliated to Soochow University, Suzhou, 215006, People's Republic of China. (b) Department of Urology, Dushu Lake Hospital Affiliated to Soochow University, Suzhou, 215006, People's Republic of China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Managing xylazine-involved overdoses in a community harm reduction setting: lessons from Tijuana, Mexico.
Managing xylazine-involved overdoses in a community harm reduction setting: lessons from Tijuana, Mexico.
Fuente:Harm Reduction Journal
Extracto:
We describe insights about the clinical management of
combined xylazine-fentanyl involved overdoses in the field, from a community harm
reduction context where xylazine arrived suddenly spurring a large number of
overdoses. In response to the long period of post-naloxone sedation inherent to
xylazine overdoses, the clinical team learned to center oxygenation-not
consciousness-as the key parameter of interest for the titration of naloxone,
increase emphasis on field airway management, portable oxygen administration, and
scene safety, and employ xylazine testing strips for urine and direct substance
analysis to educate the patient population about health risks.
Evaluation of the antibacterial and antibiofilm effect of mycosynthesized silver and selenium nanoparticles and their synergistic effect with antibiotics on nosocomial bacteria.
Evaluation of the antibacterial and antibiofilm effect of mycosynthesized silver and selenium nanoparticles and their synergistic effect with antibiotics on nosocomial bacteria.
Fuente:Microbial Cell Factories
Extracto:
Our study demonstrated that the mycosynthesized SeNPs had remarkable
antibacterial effect while, mycosynthesized AgNPs exhibited a considerable
antibiofilm effect. Both NPs exhibited higher synergistic effect with antibiotics
with different modes of action. This approach could potentially enhance the
efficacy of existing antibiotics, providing a new weapon against drug-resistant
bacteria where the described silver and selenium nanoparticles play a pivotal
role in revolutionizing healthcare practices, offering innovative solutions to
combat antibiotic resistance, and contributing to the development of advanced
medical technologies.
Effect of intramuscular treatment with different iron dextran dosages and non-inferiority study to gleptoferron.
Effect of intramuscular treatment with different iron dextran dosages and non-inferiority study to gleptoferron.
Fuente:Acta Veterinaria Scandinavica
Extracto:
In this investigation gleptoferron and iron dextran appear equally
appropriate for prevention of iron deficiency anaemia. Piglets of different birth
weights might profit differently from an additional iron administration, so that
usage of a product containing iron as a single substance is of advantage to allow
a flexible adjustment of dosage during the suckling period.
Claves:Anaemia, Average daily weight gain, Birth weight, Haemoglobin, Packed cell volume
Cita:Acta Vet Scand 2025 Jan 4; 67 (1) : 1.
Autor/es:Hennig-Pauka, Isabel (a) Ganter, Martin (b)
institución:(a) Field Station for Epidemiology, University of Veterinary Medicine Hannover, Foundation, Buescheler Straße 9, D-49456, Bakum, Germany. isabel.hennig-pauka@tiho-hannover.de. (b) Clinic for Swine, Small Ruminants, Forensic Medicine and Ambulatory Service, University of Veterinary Medicine Hannover, Foundation, Bischofsholer Damm 15, D-30173, Hannover, Germany.
Conflicto:Declarations. Consent for publication: Not applicable. Competing interests: This study was financially supported by Pharmacosmos A/S (Holbaek, Denmark). Author Wesley Lyons was employed by the company Pharmacosmos A/S. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Pharmacosmos A/S was neither...
involved in performance of study, data evaluation or data interpretation. Ethics approval: Pigs were housed in accordance with the German regulations on pig husbandry and the national animal welfare law. Husbandry conditions and the animal trial procedure follow regulations of the European Convention concerning the protection of vertebrate animals and followed the Directive of the European Convention for the Protection of Vertebrae Animals used for Experimental and Other Scientific Purposes (European Treaty Series, nos. 123). The study was approved from the local permitting authorities in the Lower Saxony State Office for Consumer Protection and Food Safety and in accordance with the requirements of the national animal welfare law (approval number: 33.19-42502-04-22-00132) following the guidelines of FELASA and ARRIVE. The animals were handled according to high ethical standards and national legislation. Unnecessary suffering was avoided by precautions taken at all stages of the experiment, as e.g. blood sampling was performed by an experienced and skilled veterinarian. Pigs were continuously observed during the whole experiment. Humane intervention points were defined for circulatory failure during life-threatened emergency and drug intolerance situations. Decisions for euthanasia due to diseases were based on medical and ethical considerations [61]. Euthanasia was conducted by injection of 60 mg pentobarbital/kg bw intravenously. All animal procedures were approved by the Lower Saxony State Office for Consumer Protection and Food Safety. Prior publication: Data have not been published previously.
Genotypic difference in response to copper stress in upland cotton as revealed by physiological and molecular expression analyses.
Genotypic difference in response to copper stress in upland cotton as revealed by physiological and molecular expression analyses.
Fuente:Bmc Plant Biology
Extracto:
To cope with Cu toxicity, the Cu-tolerant genotype activates its
antioxidative defense system, immobilizing chemically active Cu ions, and
lowering the Cu uptake, bioavailability and immigration within cells by
regulating the expressions of genes related to Cu uptake, transport, delivery and
cell wall metabolism. This comprehensive comparison study provides insights into
breeding Cu-tolerant cotton cultivars that can be utilized for the
phytoremediation of Cu-contaminated soils.
Claves:Gossypium hirsutum L., Cu toxicity, Cu transporting, Reactive oxygen species, Subcellular distribution
Cita:BMC Plant Biol 2025 Jan 6; 25 (1) : 21.
Autor/es:Wu, Jianfei (a) Wang, Tao (b)
institución:(a) Key Laboratory of Crop Physiology, Ecology and Genetic Breeding, Ministry of Education, College of Agronomy, Jiangxi Agricultural University, Nanchang, 330045, China. (b) Jiangxi Provincial Key Laboratory of Plantation and High Valued Utilization of Specialty Fruit Tree and Tea, Cash Crops Research Institute of Jiangxi Province, Nanchang, 330000, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Association between vascular endothelial growth factor and atrial fibrillation
Association between vascular endothelial growth factor and atrial fibrillation
Fuente:Bmc Cardiovascular Disorders
Tipo de trabajo:Revisión sistemática
Extracto:
VEGF is potentially a significant contributor to AF
pathophysiology, with its levels reflecting disease activity. The variability
observed across studies suggests a need for standardized measurement approaches
and further investigation into VEGF subtypes. Future research should focus on
longitudinal studies to better understand the causal relationships and the
potential of VEGF as a therapeutic target and biomarker in AF management.
CLINICAL TRIAL NUMBER: Not applicable.
institución:(a) Department of Pharmacy Practice, National Institute of Pharmaceutical Education and Research, Guwahati, 781101, India. (b) Division of Evidence Synthesis, Global Consortium of Public Health and Research, Datta Meghe Institute of Higher Education, Wardha, India.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Agro-morphological characterization and assessment of metabolic profiling and anticancer activities in various tribulus (Tribulus terrestris L.) populations.
Agro-morphological characterization and assessment of metabolic profiling and anticancer activities in various tribulus (Tribulus terrestris L.) populations.
Fuente:Bmc Plant Biology
Extracto:
terrestris populations in the studied traits shows its high potential for
selecting and using the best populations in domestication, breeding, and
cultivation projects.
Claves:Diosgenin, HPLC, Multivariate analysis, Phenolic compounds, Prostate cancer
institución:(a) Department of Agriculture, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, Tehran, Iran. (b) Department of Agriculture, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, Tehran, Iran. gh_eghlima@sbu.ac.ir.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
The cardioprotective effects of HTK solution and conventional blood cardioplegia in patients with atrial fibrillation undergoing valvular replacement and Cox maze III procedure.
The cardioprotective effects of HTK solution and conventional blood cardioplegia in patients with atrial fibrillation undergoing valvular replacement and Cox maze III procedure.
Fuente:Journal of Cardiothoracic Surgery
Extracto:
Both the HTK and 4:1 blood
cardioplegia could be used safely in patients with AF who were subject to
valvular replacement and Cox maze III procedure. However, the utilization of HTK
conferred a greater advantage in diminishing the duration of mechanical
ventilation weaning and the duration of postoperative hospitalization. HTK may be
a better myocardial protection in patients with long cross-clamp time. The
follow-up data indicated that HTK might be superior to 4:1 blood cardioplegia in
the short-medium term cardiac function.
institución:(a) Department of Anesthesiology, Women's Hospital of Nanjing Medical University, Nanjing Women and Children's Healthcare Hospital, No. 123, Tianfei Lane, Mochou Road, Nanjing, Jiangsu, 210004, China. (b) Department of Cardiothoracic Surgery, Affiliated Jinling Hospital, Nanjing Medical University, Zhongshan East Road 305, Nanjing, Jiangsu, 210002, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Telehealth equity and access communication skills pilot simulation for practicing clinicians.
Telehealth equity and access communication skills pilot simulation for practicing clinicians.
Fuente:Plos One
Extracto:
The findings of this pilot
study highlight the potential of simulation-based telehealth training for
practicing clinicians, emphasizing clinicians' attention to patients' equitable
access to healthcare. Future studies should aim to explore the durability of
learning and investigate the generalizability of this training approach to other
telehealth competencies and settings.
Cita:PLoS One 2025; 20 (1) : e0302804.
Autor/es:Nash, Christopher J (a) Farrell, Susan E (b)
institución:(a) Department of Emergency Medicine, Duke University Hospital, Durham, North Carolina, United States of America. (b) Harvard Medical School, Boston, Massachusetts, United States of America.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
An E-Delphi study to facilitate animal welfare assessment in Italian zoos and aquaria.
An E-Delphi study to facilitate animal welfare assessment in Italian zoos and aquaria.
Fuente:Plos One
Extracto:
These
questions can be the basis of fine-tuned protocols to be tested in future
projects aiming at animal welfare self-assessment, thus supporting authority
inspection processes.
Cita:PLoS One 2025; 20 (1) : e0309760.
Autor/es:de Mori, Barbara (a) Mercugliano, Elena (b)
institución:(a) Department of Comparative Biomedicine and Food Science, University of Padua, Padua, Italy. (b) Ethics Laboratory for Veterinary Medicine, Conservation and Animal Welfare, University of Padua, Padua, Italy.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Determination of antibacterial and antioxidant potential of organic crude extracts from Malus domestica, Cinnamomum verum and Trachyspermum ammi.
Determination of antibacterial and antioxidant potential of organic crude extracts from Malus domestica, Cinnamomum verum and Trachyspermum ammi.
Fuente:Scientific Reports
Extracto:
This study
has compared three potential medicinal plants with biological active and
eco-friendly components which play crucial role in therapeutics.
Claves:Antimicrobial, Antioxidant, Plant extracts
Cita:Sci Rep 2025 Jan 6; 15 (1) : 976.
Autor/es:Irshad, Asma (a) Jawad, Rabbia (b)
institución:(a) School of Biochemistry and Biotechnology, University of the Punjab, Lahore, Pakistan. (b) School of Biological Sciences, University of the Punjab, Lahore, Pakistan.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Department of Anesthesiology, Second Affiliated Hospital of Harbin Medical University, 246 Xuefu Road, Nangang District, Harbin, 150086, Heilongjiang Province, China. (b) The Key Laboratory of Anesthesiology and Intensive Care Research of Heilongjiang Province, Harbin, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
The fundamentals of eye tracking part 4: Tools for conducting an eye tracking study.
The fundamentals of eye tracking part 4: Tools for conducting an eye tracking study.
Fuente:Behavior Research Methods
Extracto:
This article provides an overview of
available tools for research using eye trackers and discusses considerations to
make when choosing which tools to adopt for one's study.
Autor/es:Niehorster, Diederick C (a) Nyström, Marcus (b)
institución:(a) Lund University Humanities Lab and Department of Psychology, Lund University, Lund, Sweden. diederick_c.niehorster@humlab.lu.se. (b) Lund University Humanities Lab, Lund University, Lund, Sweden.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Community-based newborn care utilization and associated factors in Nekemte City, Oromia, Ethiopia, 2023.
Community-based newborn care utilization and associated factors in Nekemte City, Oromia, Ethiopia, 2023.
Fuente:Bmc Pediatrics
Extracto:
Community-based newborn care utilization was low from the study area
in related to the previous studies and national recommendation. Therefore,
creating awareness for mothers to start their antenatal contacts early or at the
first trimester, giving information about community-based utilization of newborn
care services to teenagers, and supporting mothers who are widowed and of medium
or high income to use the community-based utilization of newborn care services.
Claves:Community-based, Ethiopia, Factors, New-born care, Utilization
institución:(a) Department of Pediatrics and Neonatal Nursing, School of Nursing and Midwifery, Institute of Health Sciences, Wollega University, Nekemte, Ethiopia. dawitt635@gmail.com. (b) Department of Pediatrics and Neonatal Nursing, School of Nursing and Midwifery, Institute of Health Sciences, Wollega University, Nekemte, Ethiopia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
External validation of AI-based scoring systems in the ICU
External validation of AI-based scoring systems in the ICU
Fuente:Bmc Medical Informatics and Decision Making
Tipo de trabajo:Revisión sistemática
Extracto:
Interpretation of the
results was challenged by an overreliance on the same few datasets, implicit
differences in case mix, and exclusive use of AUROC.
Claves:Acute deterioration, Electronic health records, External validation, Intensive care unit, Machine learning
Cita:BMC Med Inform Decis Mak 2025 Jan 6; 25 (1) : 5.
Autor/es:Rockenschaub, Patrick (a) Akay, Ela Marie (b)
institución:(a) CLAIM - Charité Lab for AI in Medicine, Charité - Universitätsmedizin Berlin, Berlin, Germany. (b) QUEST Center for Responsible Research, Berlin Institute of Health at Charité Universitätsmedizin Berlin, Berlin, Germany.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Influences of school climate on emotional health and academic achievement of school-going adolescents in India
Influences of school climate on emotional health and academic achievement of school-going adolescents in India
Fuente:Bmc Public Health
Tipo de trabajo:Revisión sistemática
Extracto:
The review considerably evidenced the significance of
school climate in determining school-going adolescents' emotional health and
academic achievement. This indicated the requirement to implement school-based
intervention packages in secondary schools to improve the school climate. The
whole school approach could be a better strategy for intervention. CLINICAL TRIAL
NUMBER: Not applicable.
Claves:Academic achievement, Adolescents, Emotional health, India, School climate, Secondary schools, Systematic review
institución:(a) Department of Psychiatric Social Work, National Institute of Mental Health and Neurosciences, Bengaluru, 560029, India. (b) Department of Psychiatric Social Work, National Institute of Mental Health and Neurosciences, Bengaluru, 560029, India. janardhannimhans@gmail.com.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Prognostic value of systemic immune-inflammation index in patients with small-cell lung cancer treated with immune checkpoint inhibitors.
Prognostic value of systemic immune-inflammation index in patients with small-cell lung cancer treated with immune checkpoint inhibitors.
Fuente:Bmc Cancer
Extracto:
Elevated SII in the initial phase of ICI maintenance therapy was
associated a with poor prognosis in patients with SCLC, supporting its utility as
a prognostic biomarker in this setting. Therefore, prospective validation is
required to confirm these findings.
institución:(a) Department of Respiratory Medicine and Oncology, Yokohama Municipal Citizen's Hospital, 1-1, Mitsuzawa Nishimachi, Kanagawa Ku, Yokohama, 221-0855, Japan. yu00-hamakawa@hosp.city.yokohama.lg.jp. (b) Department of Respiratory Medicine and Oncology, Yokohama Municipal Citizen's Hospital, 1-1, Mitsuzawa Nishimachi, Kanagawa Ku, Yokohama, 221-0855, Japan.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Prophylactic barrage laser in patients with previous vitreous loss during cataract surgery
Prophylactic barrage laser in patients with previous vitreous loss during cataract surgery
Fuente:Bmc Ophthalmology
Tipo de trabajo:Estudio clínico aleatorizado
Extracto:
Prophylactic barrage laser might be a
useful intervention in eyes with posterior capsule rupture and vitreous loss
during cataract surgery to prevent rhegmatogenous retinal detachment. However,
further studies with larger sample sizes are indicated. TRIAL REGISTRATION:
Iranian Clinical Trial Registry: IRCT20201120049450N2, Registered 13 Jul 2023,
https://irct.behdasht.gov.ir .
institución:(a) Poostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. (b) Poostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Evaluation of glomerular filtration rate estimation through plasma clearance of iohexol in seagulls (Larus michahellis).
Evaluation of glomerular filtration rate estimation through plasma clearance of iohexol in seagulls (Larus michahellis).
Fuente:Bmc Veterinary Research
Extracto:
The findings revealed that
IOX plasma clearance was a reliable, accurate, and clinically applicable approach
to calculating seagull GFR. This strategy might help with the validation and
subsequent development of clinical renal biomarkers.
institución:(a) Department of Veterinary Sciences, Veterinary Teaching Hospital "Mario Modenato", University of Pisa, via Livornese snc, San Piero a Grado, Pisa, Italy. matilde.vernaccini@phd.unipi.it. (b) Department of Veterinary Sciences, Veterinary Teaching Hospital "Mario Modenato", University of Pisa, via Livornese snc, San Piero a Grado, Pisa, Italy.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Feels Like Home: A Biobased and Biodegradable Plastic Offers a Novel Habitat for Diverse Plant Pathogenic Fungi in Temperate Forest Ecosystems.
Feels Like Home: A Biobased and Biodegradable Plastic Offers a Novel Habitat for Diverse Plant Pathogenic Fungi in Temperate Forest Ecosystems.
Fuente:Microbial Ecology
Extracto:
Nevertheless, it
should be noted that our interpretation of plant pathogens is solely based on
high-throughput sequencing, bioinformatics, and annotation tools.
institución:(a) Institute of Bioanalysis, Coburg University of Applied Sciences and Arts, Coburg, Germany. (b) Department of Biology, Faculty of Science, Chiang Mai University, Chiang Mai, 50200, Thailand.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
