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A new normal in primary care: the rapid normalization of a major eHealth program in public health centers.
A new normal in primary care: the rapid normalization of a major eHealth program in public health centers.
Fuente:Bmc Health Services Research
Tipo de trabajo:Revisión
Extracto:
In relation to
the rapid progression of different initiatives in eHealth, this study contributes
to perspectives on specific challenges as expressed by professions directly
linked to both strategic and functional implementation as well as administration
and clinical operation.
Claves:Implementation; eHealth; Telemedicine; Primary care
Cita:BMC Health Serv Res 2024 Nov 15; 24 (1) : 1409.
Autor/es:Maack, Karl (a) Gillberg, Nanna (b)
institución:(a) Institute of Medicine, University of Gothenburg, Gothenburg, Sweden. karl.maack@gu.se. (b) Department of Business Administration, University of Gothenburg, Gothenburg, Sweden.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Exposure to air pollutants and breast cancer risk: mediating effects of metabolic health biomarkers in a nested case-control study within the E3N-Generations cohort.
Exposure to air pollutants and breast cancer risk: mediating effects of metabolic health biomarkers in a nested case-control study within the E3N-Generations cohort.
Fuente:Breast Cancer Research Bcr
Extracto:
Although limited by a lack of statistical power, this
study provides relevant insights into the potential mediating role of certain
biomarkers in the association between air pollutant exposure and breast cancer
risk, highlighting the need for further in-depth studies in large populations.
Claves:Air pollutants, Biomarkers, Breast cancer, Interaction, Mediation
institución:(a) Department of Prevention Cancer Environnement, Centre Léon Bérard, Lyon, France. (b) Inserm U1296 Radiations Défense, Santé, Environnement, Lyon, France.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Supportive care in cancer official journal of the Multinational Association of Supportive Care in Cancer
Selección SIIC: 21 Noviembre, 2024
Supportive care in cancer official journal of the Multinational Association of Supportive Care in Cancer
Navigating shared decision-making after the Life-Sustaining Treatment Decision Act: a qualitative study of in-depth interviews with terminal cancer patients, families, and healthcare professionals.
Navigating shared decision-making after the Life-Sustaining Treatment Decision Act: a qualitative study of in-depth interviews with terminal cancer patients, families, and healthcare professionals.
Fuente:Supportive Care in Cancer Official Journal of The Multinational Association of Supportive Care in Cancer
Extracto:
The
proposed "6C" framework provides insights into addressing current challenges in
SDM and emphasizes the importance of cultural norms and ethical obligations in
end-of-life decision-making. Further research is warranted to examine the SDM
process in diverse cultural contexts and develop interventions to enhance patient
and family involvement in the decision-making process for LST.
Cita:Support Care Cancer 2024 Nov 16; 32 (12) : 796.
Autor/es:Yu, Soo-Young (a) Lee, Yu-Eun (b)
institución:(a) College of Nursing, Chonnam National University, 160 Baekseo-Ro, Dong-Gu, Gwangju, 61469, Republic of Korea. (b) Division of Hematology and Medical Oncology, Dongguk University Ilsan Hospital, Goyang, Republic of Korea.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Metamaterial-based Artificial magnetic conductor for efficient breast cancer diagnosis using a low-cost antenna array.
Metamaterial-based Artificial magnetic conductor for efficient breast cancer diagnosis using a low-cost antenna array.
Fuente:Scientific Reports
Extracto:
The outcomes of this research bear
considerable implications for advancing early-stage breast cancer detection
methodologies.
Claves:Artificial Magnetic Conductor (AMC), Biosensor, Metamaterials (MMTs), Microwave Breast Imaging Systems (MWBIS), Modern Antenna Array, Non-Invasive Breast Cancer detection, Tumor Detection
Cita:Sci Rep 2024 Nov 16; 14 (1) : 28262.
Autor/es:Hamza, Musa N (a) Abdulkarim, Yadgar I (b)
institución:(a) Department of Physics, College of Science, University of Raparin, Sulaymaniyah, 46012, Iraq. (b) Physics Department, College of Science, Charmo University, 46023, Chamchamal, Sulaimania, Kurdistan Region, Iraq.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Intimate Partner Violence during the Index Pregnancy and its correlates among a panel of pregnant women in Ethiopia, evidence from performance, and monitoring for action (PMA) 2021 cohort two baseline survey.
Intimate Partner Violence during the Index Pregnancy and its correlates among a panel of pregnant women in Ethiopia, evidence from performance, and monitoring for action (PMA) 2021 cohort two baseline survey.
Fuente:Bmc Pregnancy and Childbirth
Extracto:
The overall
burden of IPV reported was high; with nearly double the percentage of women
experiencing sexual violence during the index pregnancy compared to physical IPV.
More work needs to be done to achieve zero tolerance against any form of violence
among women and girls in general and among pregnant women in particular. Efforts
targeted in improving women perception on issue related with their contraceptive
use, counseling women on how to prevent IPV during their antenatal care (ANC)
visit along with advising the use of inter pregnancy contraception and empowering
them to control on their fertility are hoped to mitigate such considerably higher
odds of IPV among pregnant women. Further programs and intervention on awareness
creation towards the misconception that women held about contraceptive use would
contribute much. These activities and efforts need to target younger women. The
implication of the findings calls key actors and the Federal Democratic Republic
of Ethiopia Health Minster to design and implement programs on women emotional
fertility readiness and empowering them to control over their fertility through
diversified contraceptive provision which is critical in combating the reported
substantial IPV experience during pregnancy. Creating institutional capacity in
the health system through strengthening and expanding one stop centers to provide
medical treatment, care, and psychosocial support for victims and survivors could
play a pivotal role. In addition, installing rapid referral system and linkage to
the legal system could play a vital role. Moreover, working on early marriage and
counseling on childbirth; and spaced pregnancy for those young couples is
imperative. Further implication of this study was installing contraceptive and
violence related preconception care packages in the health system is very
critical in the combat against IPV and any form of gender based violence.
Claves:Cohort data, Ethiopia, Intimate partner violence, PMA, Physical Intimate Partner Violence, Sexual Intimate Partner Violence, Women Health
Cita:BMC Pregnancy Childbirth 2024 Nov 16; 24 (1) : 759.
institución:(a) Department of Epidemiology and Biostatistics, School of Public Health, Woliata Sodo University, Wolaita Sodo, Ethiopia. abrsole2006@gmail.com. (b) School of public health, Addis Ababa University, Addis Ababa, Ethiopia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Towards precision medicine: design considerations for nanozymes in tumor treatment.
Towards precision medicine: design considerations for nanozymes in tumor treatment.
Fuente:Journal of Translational Medicine
Extracto:
By identifying the
challenges and opportunities in the field, this study aims to provide a
foundation for future nanozyme development, ultimately contributing to more
precise and effective cancer treatments.
institución:(a) Department of Neurosurgery, The First Hospital of China Medical University, Nanjing Street 155, Heping district, Shenyang, 110001, People's Republic of China. (b) Department of Neurosurgery, The First Hospital of China Medical University, Nanjing Street 155, Heping district, Shenyang, 110001, People's Republic of China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Antiviral properties and molecular docking studies of eco-friendly biosynthesized copper oxide nanoparticles against alfalfa mosaic virus.
Antiviral properties and molecular docking studies of eco-friendly biosynthesized copper oxide nanoparticles against alfalfa mosaic virus.
Fuente:Bmc Plant Biology
Extracto:
The overall
analysis results indicate that the curative treatment is more influential and
successful than the protective treatment in combating AMV infection.
Consequentially, CuO-NPs could potentially be employed in foliar sprays for the
effective and environmentally friendly management of plant virus infections.
institución:(a) Plant Protection and Biomolecular Diagnosis Department, Arid Lands Cultivation Research Institute, City of Scientific Research and Technological Applications, Alexandria, 21934, Egypt. (b) Department of Botany and Microbiology, Faculty of Science, Alexandria University, Alexandria, 21511, Egypt.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Risk of Hepatocellular Carcinoma with Glucagon-like Peptide-1 receptor agonist treatment in patients
Risk of Hepatocellular Carcinoma with Glucagon-like Peptide-1 receptor agonist treatment in patients
Fuente:Bmc Endocrine Disorders
Tipo de trabajo:Revisión sistemática
Extracto:
GLP-1 RAs may offer protective benefits against HCC in T2DM patients
compared to insulin or no GLP-1 RAs, but not significantly over other
antidiabetic medications. This review indicates the need for further randomized
controlled trials to clarify the role of GLP-1 RAs in HCC risk mitigation and to
explore their mechanistic pathways in liver disease management.
Autor/es:Shabil, Muhammed (a) Khatib, Mahalaqua Nazli (b)
institución:(a) University Center for Research and Development, Chandigarh University, Mohali, Punjab, India. (b) Medical Laboratories Techniques Department, AL-Mustaqbal University, Hillah, Babil, 51001, Iraq.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Effect of combined treatment with transcranial direct current stimulation and repetitive transcranial magnetic stimulation compared to monotherapy for the treatment of chronic insomnia: a randomised, double-blind, parallel-group, controlled trial.
Effect of combined treatment with transcranial direct current stimulation and repetitive transcranial magnetic stimulation compared to monotherapy for the treatment of chronic insomnia: a randomised, double-blind, parallel-group, controlled trial.
Fuente:Bmc Medicine
Tipo de trabajo:Estudio clínico
Extracto:
Combining tDCS with rTMS
effectively relieved insomnia symptoms, achieving a significant therapeutic
effect after 2-week of intervention, and demonstrating the persistence of
treatment effects in later follow-up, emphasising the advantages of combination
therapy in improving treatment stability and long-term benefits, reflecting the
rapid and effective augmentation of combination therapy. This combined therapy
may serve as a safe and effective treatment for adults with chronic insomnia.
TRIAL REGISTRATION: This study was registered as a clinical trial with the China
Clinical Trial Registration Center (ChiCTR2100052681).
Claves:Chronic insomnia, Clinical trial, Combined therapy, Repetitive transcranial magnetic stimulation, Transcranial direct current stimulation
Cita:BMC Med 2024 Nov 18; 22 (1) : 538.
Autor/es:Zhou, Qi (a) Liu, Zhiwang (b)
institución:(a) Department of Psychiatry, Ningbo Kangning Hospital & Affiliated Mental Health Centre, Ningbo Key Laboratory for Physical Diagnosis and Treatment of Mental and Psychological Disorders, Ningbo University, Ningbo, Zhejiang, 315201, China. (b) Department of Psychiatry, Ningbo Kangning Hospital, Ningbo, Zhejiang, 315201, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Integrative Lipid Pseudotargeted Metabolomics and Amino Acids Targeted Metabolomics Unravel the Therapeutic Mechanism of Rhizoma Paridis Saponins on Experimental Colitis of Damp-Heat Type.
Integrative Lipid Pseudotargeted Metabolomics and Amino Acids Targeted Metabolomics Unravel the Therapeutic Mechanism of Rhizoma Paridis Saponins on Experimental Colitis of Damp-Heat Type.
Fuente:Drug Design, Development and Therapy
Extracto:
These results showed
that RPTS (50 mg/kg) and PN (20 mg/kg) effectively alleviated rats' colitis of
damp-heat type, affected cytokines, and altered lipid metabolism without
significant modulation on amino acid metabolism.
institución:(a) Department of Traditional Chinese Medicine, Nanjing Drum Tower Hospital, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, 210008, People's Republic of China. (b) Department of Gastroenterology, The 981th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army, Chengde, Hebei, 067000, People's Republic of China.
Conflicto:Prof. Dr. Wu Jing reports grants from the National Natural Science Foundation of China and grants from Nanjing Drum Tower Hospital. The authors declare no other conflicts of financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Predictive risk models for COVID-19 patients using the multi-thresholding meta-algorithm.
Predictive risk models for COVID-19 patients using the multi-thresholding meta-algorithm.
Fuente:Scientific Reports
Extracto:
This model not only enhances predictive
accuracy but also supports critical decision-making processes in healthcare,
potentially improving patient outcomes and optimizing clinical resource
allocation.
Autor/es:Delgado, Rosario (a) Fernández-Peláez, Francisco (b)
institución:(a) Department of Mathematics, Universitat Autònoma de Barcelona, Barcelona, Spain. Rosario.Delgado@uab.cat. (b) Applied Artificial Intelligence Unit, Eurecat, Barcelona, Spain.
Conflicto:Declarations Conflict of interest The authors declare no potential conflict of interests nor competing interests.github.com/RosDelgado/MTh Code availability The computer programming code (R function) that has been developed and utilized in this study, to implement Algorithm 1 (the Multi-Thresholding meta-algorithm, MTh) is accessible under an open-access (MIT) license. You can find it at https://github.com/RosDelgado/MTh. Ethical implications The use of predictive models in...
n clinical settings raises several important ethical considerations. First and foremost, privacy and data security are critical: patient data used for training and validating models must be protected, and all practices must comply with data protection regulations. Second, it is essential to address potential biases within the model to ensure that predictions are equitable across different patient groups and to prevent discrimination in care. Third, predictive models should be used to complement, rather than replace, clinical judgment. It is important to be transparent about the limitations and uncertainties inherent in the model’s predictions. Lastly, patients should be adequately informed about the use of predictive models in their care. Clear communication is necessary to help patients to understand how these models influence clinical decisions.
Comparison of functional outcome after intracerebral hemorrhage in patients with or without end stage renal disease on hemodialysis: a propensity-score matched study.
Comparison of functional outcome after intracerebral hemorrhage in patients with or without end stage renal disease on hemodialysis: a propensity-score matched study.
Fuente:Bmc Neurology
Extracto:
ICH patients with ESRD on HD had significantly higher
in-hospital mortality and lower rate of obesity than propensity score matched
controls, suggesting a survival benefit from obesity. ICH score ≥ 3 is an
independent predictor for poor outcomes in both ESRD and non-ESRD groups.
institución:(a) Department of Neurology, University of California, Irvine, 200 S. Manchester Ave. Suite 206, Orange, CA, 92868, USA. ktsutsum@hs.uci.edu. (b) School of Medicine, University of California, Irvine, Orange, CA, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Characterization of frost-tolerant plum genotypes (Prunus domestica L.) in Nishabur region, Iran: a morphological and phenological assessment following natural spring frost event.
Characterization of frost-tolerant plum genotypes (Prunus domestica L.) in Nishabur region, Iran: a morphological and phenological assessment following natural spring frost event.
Fuente:Bmc Plant Biology
Extracto:
This research highlights the
presence of frost-tolerant genotypes and varieties with suitable environmental
adaptability in the Nishabur region, demonstrating relatively acceptable
diversity. These genotypes hold potential for breeding and germplasm conservation
purposes.
Claves:Prunus domestica, Breeding, Germplasm conservation, Spring frost, Superior genotypes
Cita:BMC Plant Biol 2024 Nov 19; 24 (1) : 1098.
Autor/es:Borji, Mehdi (a) Rezaei, Mehdi (b)
institución:(a) Horticulture Department, Agriculture Faculty, Shahrood University of Technology, Shahrood, Iran. (b) Horticulture Department, Agriculture Faculty, Shahrood University of Technology, Shahrood, Iran. Mhrezaei@shahroodut.ac.ir.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Engineering an Escherichia coli strain for enhanced production of flavonoids derived from pinocembrin.
Engineering an Escherichia coli strain for enhanced production of flavonoids derived from pinocembrin.
Fuente:Microbial Cell Factories
Extracto:
Through the
integration of microbial chassis engineering and screening of enzyme candidates,
we considerably increased the production levels of microbially synthesised
pinocembrin, chrysin, pinostrobin, pinobanksin, and galangin. With the
introduction of additional chassis modifications geared towards improving
cofactor supply and regeneration, as well as alleviating potential toxic effects
of intermediates and end products, we anticipate further enhancements in the
yields of these pinocembrin derivatives, potentially enabling greater
diversification in microbial hosts.
Autor/es:Hanko, Erik K R (a) Robinson, Christopher J (b)
institución:(a) Manchester Institute of Biotechnology, Faculty of Science and Engineering, University of Manchester, 131 Princess Street, Manchester, M1 7DN, UK. (b) Manchester Institute of Biotechnology, Faculty of Science and Engineering, University of Manchester, 131 Princess Street, Manchester, M1 7DN, UK.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Forecasting the future of smart hospitals: findings from a real-time delphi study.
Forecasting the future of smart hospitals: findings from a real-time delphi study.
Fuente:Bmc Health Services Research
Tipo de trabajo:Guía
Extracto:
The findings from our real-time Delphi study suggest that the vision of smart
hospitals is gradually becoming reality over the next 20 years. Advancements in
artificial intelligence should enhance operational efficiency and patient-centric
care, while facilitating the integration of sustainability practices and
fostering collaborative ecosystems. However, addressing challenges such as staff
shortages, ethical considerations, and the need for robust digital skills will be
essential. A deep pool of expert healthcare practitioners, clear ethical
guidelines, and robust digital skills are essential to fully realize this vision
and ensure that smart hospitals can meet the evolving needs of healthcare
delivery.
Cita:BMC Health Serv Res 2024 Nov 18; 24 (1) : 1421.
Autor/es:Jovy-Klein, Florian (a) Stead, Susan (b)
institución:(a) RWTH Aachen University, Institute for Technology and Innovation Management, Kackerstr. 7, Aachen, 52072, Germany. jovy-klein@time.rwth-aachen.de. (b) RWTH Aachen University, Institute for Technology and Innovation Management, Kackerstr. 7, Aachen, 52072, Germany.
Conflicto:Declarations Ethics approval and consent to participate Each participant provided consent within the real-time Delphi platform before the study began. Consent for publication Not applicable. Competing interests Dr. Anke Diehl is Chairwoman of the Supervisory Board of Dr. Jäschke AG and a member of the Interop Council and has received lecture/consulting fees from ValueBasedManagedCare GmbH, Janssen-Cilag GmbH, Getinge Deutschland GmbH,...
, EIT Health Germany GmbH, Face-to-face GmbH, Siemens AG, gematik GmbH, MCE – Medical Congresses & Events e.K. für Medizinische Gesellschaft Ost-Brandenburg, Pfizer GmbH and BKK Landesverband Bayern.No other conflicts of interest declared.
Regulation, modification, and evolution of remote sign language interpreting in Sweden - a service in progress.
Regulation, modification, and evolution of remote sign language interpreting in Sweden - a service in progress.
Fuente:Bmc Health Services Research
Extracto:
In Sweden, remote interpreting is a service that varies according to
regulations and the type of assignments. The service would benefit from being
more uniform and streamlined across Sweden, although consideration must be given
to those involved with the service.
Cita:BMC Health Serv Res 2024 Nov 19; 24 (1) : 1431.
Autor/es:Warnicke, Camilla (a) Matérne, Marie (b)
institución:(a) University Health Care Research Center, Faculty of Medicine and Health, Örebro University Hospital, Region Örebro County, Box 1613, Örebro, 701 16, Sweden. camilla.warnicke@oru.se. (b) School of Behavioural, Social and Legal Sciences, Örebro University, Fakultetsgatan 1, Örebro, 701 82, Sweden. camilla.warnicke@oru.se.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Predicting two-year return-to-sport failure after medial patellofemoral ligament reconstruction in patellar dislocation patients with bone abnormalities.
Predicting two-year return-to-sport failure after medial patellofemoral ligament reconstruction in patellar dislocation patients with bone abnormalities.
Fuente:Journal of Orthopaedic Surgery and Research
Extracto:
The study developed a
personalized predictive nomogram with 4 predictors (increased TT-TG distance,
trochlear dysplasia, increased femoral anteversion angle, and patellar alta) that
allowed surgeons to stratify the risk of failure to return to sport after medial
patellofemoral ligament reconstruction and recommend skeletal surgery for
patients with these factors. LEVEL OF EVIDENCE: Level III.
institución:(a) Department of Orthopaedic Surgery, Hebei Medical University Third Hospital, Shijiazhuang, 050051, Hebei, China. (b) Department of Orthopaedic Surgery, Affiliated Hospital of Hebei University, Baoding, 071000, Hebei, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Analysis of public perceptions on the use of artificial intelligence in genomic medicine.
Analysis of public perceptions on the use of artificial intelligence in genomic medicine.
Fuente:Human Genomics
Extracto:
The insights
gained from these discussions help to understand public concerns around the use
of AI in genomic medicine. Our findings can help to inform both policies around
genomic AI and how to educate the public on its use.
institución:(a) Department of Paediatrics, The University of Melbourne, Parkville, 3052, Australia. (b) Murdoch Children's Research Institute, Parkville, 3052, Australia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Platelet-rich plasma: A bibliometric and visual analysis from 2000 to 2022.
Platelet-rich plasma: A bibliometric and visual analysis from 2000 to 2022.
Fuente:Medicine
Extracto:
The bibliometric analysis of PRP research reveals a multifaceted
array of applications across various medical disciplines and highlights areas
requiring further exploration, particularly in standardization, personalization,
and safety. Future advancements in PRP research will necessitate innovative
exploration, ethical considerations, and rigorous scientific validation to fully
harness the therapeutic potential of PRP and related therapies.
Cita:Medicine (Baltimore) 2024 Nov 15; 103 (46) : e40530.
Autor/es:Du, Kai (a) Li, Ao (b)
institución:(a) Beijing University of Chinese Medicine, Beijing, People's Republic of China. (b) Beijing University of Chinese Medicine, Beijing, People's Republic of China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Leveraging Open-Source Large Language Models for Data Augmentation in Hospital Staff Surveys: Mixed Methods Study.
Leveraging Open-Source Large Language Models for Data Augmentation in Hospital Staff Surveys: Mixed Methods Study.
Fuente:Jmir Medical Education
Extracto:
The study demonstrates the value of data augmentation with
open-source LLMs, highlights the importance of privacy and ethical considerations
when using LLMs, and suggests future directions for research in this field.
Claves:AI, artificial intelligence, data augmentation, data privacy, data security, ethics, large language models, medical education, medical staff, natural language processing
Cita:JMIR Med Educ 2024 Nov 19; 10 : e51433.
Autor/es:Ehrett, Carl (a) Hegde, Sudeep (b)
institución:(a) Watt Family Innovation Center, Clemson University, Clemson, SC, United States. (b) Department of Industrial Engineering, Clemson University, Clemson, SC, United States.
