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Trauma team activation and triage of severely injured patients at one non-trauma-center hospital in Stockholm.
Trauma team activation and triage of severely injured patients at one non-trauma-center hospital in Stockholm.
Fuente:Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Tipo de trabajo:Guía
Extracto:
Undertriage of severely injured trauma patients was 98%
according to the definition specified by Swedish trauma triage guidelines, higher
than reasonably acceptable. There is considerable overtriage with non-severely
injured patients prompting TTA. However, the suitability of using NISS > 15 to
retrospectively define the need for TTA is debatable as this does not always
correlate with the fulfillment of the TTA criteria. Further investigation of
adherence to trauma triage guidelines in clinical practice may be of value to
improve triage accuracy in organized regional trauma systems.
Claves:Non-trauma-center hospital, The Swedish Trauma Registry, Trauma, Trauma team activation, Triage, Undertriage
Cita:Scand J Trauma Resusc Emerg Med 2024 Nov 27; 32 (1) : 120.
Autor/es:Lapidus, Oscar (a) Bäckström, Denise (b)
institución:(a) Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden. oscar.lapidus@ki.se. (b) Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Albumin nanoparticles are a promising drug delivery system in dentistry.
Albumin nanoparticles are a promising drug delivery system in dentistry.
Fuente:Biomedical Engineering Online
Extracto:
As a
result, in this article, we studied the usage of albumin nanoparticles in dental
disorders.
Claves:Albumin nanoparticles, Dentin and canal root infections, Drug delivery system, Peri-implantitis, Periodontitis
Cita:Biomed Eng Online 2024 Nov 27; 23 (1) : 122.
Autor/es:Kiarashi, Mohammad (a) Yasamineh, Saman (b)
institución:(a) College of Dentistry, Lorestan University of Medical Sciences, Khorramabad, Iran. (b) Young Researchers and Elite Club, Tabriz Branch, Islamic Azad University, Tabriz, Iran. yassaman124@gmail.com.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
A systematic scoping review of mentoring support on professional identity formation.
A systematic scoping review of mentoring support on professional identity formation.
Fuente:Bmc Medical Education
Tipo de trabajo:Revisión
Extracto:
The success
of mentoring in PIF lies in its ability to blend role modelling, supervision,
mentoring, coaching and teaching, with self-care, guided reflection,
apprenticeship and assessment to meet the individual needs of the mentee and
their changing circumstances. Blending the contents of the mentoring umbrella
emphasises the critical role of the mentor and host organisation in supporting
mentor training, communications, support and assessment mechanisms. Mentee
engagement and its active role in support measures complement the CoP-like
mentoring programme's use of blending mentoring support to advance the
socialisation process. These insights reflect a complex interactive process
scaffolding the development of mentoring relationships and PIF. The effect of the
mentoring umbrella on clinical practice requires further study.
Claves:Apprenticeship, Coaching, Medical schools, Medicine, Mentor, Mentoring, Mentoring relationships, Mentoring support, Professional identity formation, Role modelling, Supervision
Cita:BMC Med Educ 2024 Nov 27; 24 (1) : 1380.
Autor/es:Krishna, Lalit Kumar Radha (a) Kwok, Hannah Yi Fang (b)
institución:(a) Yong Loo Lin School of Medicine, National University of Singapore, NUHS Tower Block, Level 11, Block 1E, Kent Ridge Road, Singapore, 119228, Singapore. lalit.radha-krishna@liverpool.ac.uk. (b) Division of Supportive and Palliative Care, National Cancer Centre Singapore, 30 Hospital Boulevard, Singapore, 168583, Singapore. lalit.radha-krishna@liverpool.ac.uk.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Cita:J Nanobiotechnology 2024 Nov 27; 22 (1) : 737.
Autor/es:Feng, Yekai (a) Tang, Qinglai (b)
institución:(a) Department of Otorhinolaryngology Head and Neck Surgery, The Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, China. (b) Department of Otorhinolaryngology Head and Neck Surgery, The Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Nucleolar protein 3 promotes proliferation of bladder cancer cells through the PI3K-Akt pathway.
Nucleolar protein 3 promotes proliferation of bladder cancer cells through the PI3K-Akt pathway.
Fuente:World Journal of Surgical Oncology
Extracto:
In conclusion, our study
suggests that NOL3 is upregulated in BLCA cells and promotes proliferation via
the PI3K/Akt pathway, indicating that NOL3 may be a potential therapeutic target
for BLCA.
institución:(a) Department of Urology, The First Affiliated Hospital of Chongqing Medical University, 1 Youyi Road, Yuzhong District, Chongqing, 400016, P.R. China. (b) Department of Urology, The First Affiliated Hospital of Chongqing Medical University, 1 Youyi Road, Yuzhong District, Chongqing, 400016, P.R. China.
Conflicto:Declarations. Conflict of interest: The authors declare that they have no conflict of interest. Institutional Review Board Statement: The study was conducted in accordance with the Declaration of Helsinki and approved by the Institutional Review Board (or Ethics Committee) of The First Affiliated Hospital of Chongqing Medical University (protocol code 2021-085 and 3 March 2021 of approval) for studies involving...
humans. The animal study protocol was approved by the Institutional Animal Care and Use Committee (IACUC) of Chongqing Medical University (IACUC-CQMU-2023-0226). Informed consent: Informed consent was obtained from all subjects involved in the study.
GLP-1 and GIP agonism has no direct actions in human hepatocytes or hepatic stellate cells.
GLP-1 and GIP agonism has no direct actions in human hepatocytes or hepatic stellate cells.
Fuente:Cellular and Molecular Life Sciences Cmls
Extracto:
These
findings indicate that incretin agonists have no direct actions in human
hepatocytes or hepatic stellate cells, suggesting that their beneficial effects
in patients with MASH are likely mediated indirectly, potentially through
improvements in body weight, insulin resistance and glycemic control.
Claves:Fatty acids, GIPR, GLP-1R, Liver fibrosis
Cita:Cell Mol Life Sci 2024 Nov 28; 81 (1) : 468.
Autor/es:da Silva Lima, Natália (a) Cabaleiro, Alba (b)
institución:(a) Department of Physiology, CIMUS, University of Santiago de Compostela, 15782, Santiago de Compostela, Spain. (b) Department of Physiology, CIMUS, University of Santiago de Compostela, 15782, Santiago de Compostela, Spain.
Conflicto:Declarations. Conflict of interest: T.D.M. receives research funding from Novo Nordisk and has received speaking fees from Eli Lilly, AstraZeneca, Merck and Novo Nordisk. Ethical approval: All experiments were carried out in accordance with Animal Ethics Committee at the University of Santiago de Compostela. Consent for publication: All authors read and approved the submission and final publication.
Implementation strategies for providing optimised tuberculosis and diabetes integrated care in LMICs (POTENTIAL): protocol for a multiphase sequential and concurrent mixed-methods study.
Implementation strategies for providing optimised tuberculosis and diabetes integrated care in LMICs (POTENTIAL): protocol for a multiphase sequential and concurrent mixed-methods study.
Fuente:Bmj Open
Extracto:
Findings will be shared through academic publications, conferences and public
outreach.
Claves:Diabetes Mellitus, Type 2, Implementation Science, Tuberculosis
Cita:BMJ Open 2024 Nov 27; 14 (11) : e093747.
Autor/es:Afaq, Saima (a) Zala, Zala (b)
institución:(a) University of York, York, UK saima.afaq@york.ac.uk. (b) Khyber Medical University, Peshawar, Pakistan.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Who has the responsibility to inform relatives at risk of hereditary cancer? A population-based survey in Sweden.
Who has the responsibility to inform relatives at risk of hereditary cancer? A population-based survey in Sweden.
Fuente:Bmj Open
Extracto:
Our study indicates that the Swedish
public ascribes moral responsibility for informing ARRs to both the patient and
HCPs. However, contrary to current practice, they believe HCPs hold the ultimate
responsibility. The majority of respondents support disclosure even without
patient consent.
Claves:Cancer genetics, GENETICS, Gastrointestinal tumours, MEDICAL ETHICS, Risk management
Cita:BMJ Open 2024 Nov 27; 14 (11) : e089237.
Autor/es:Grill, Kalle (a) Phillips, Amicia (b)
institución:(a) Historical, Philosophical and Religious studies, Umeå University, Umeå, Sweden. (b) Centre for Biomedical Ethics and Law, Department of Public Health and Primary Care, KU Leuven, Leuven, Flanders, Belgium.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Family member experience with restricted family presence in Canadian PICUs: an interpretive descriptive study.
Family member experience with restricted family presence in Canadian PICUs: an interpretive descriptive study.
Fuente:European Journal of Pediatrics
Extracto:
RFP policies created a range
of barriers for family members of critically ill children. Healthcare
organizations and teams may play a role in removing barriers through consistent
and empathetic application of rules with consideration for the duality of the
parent role in PICUs, providing important post-pandemic policy and practice
implications. WHAT IS KNOWN: • Parental presence with critically ill children may
improve health outcomes for patients and their families. • Restrictions to family
presence in PICUs continue to occur internationally and, during COVID-19,
resulted in parental isolation, anxiety, and increased stress. What is new: • By
isolating family members and removing supports, COVID-19-related restrictions in
Canadian PICUs challenged family members' ability to fulfil their parent roles
while meeting their own needs. • Families need empathetic, advocacy-based
approaches from clinicians and healthcare systems to maintain trust and
therapeutic relationships in a family-centered organization.
Claves:COVID-19, Family members, Intensive care unit, Pediatric, Qualitative, Visitors
Cita:Eur J Pediatr 2024 Nov 29; 184 (1) : 52.
Autor/es:Foster, Jennifer R (a) Ryan, Molly J (b)
institución:(a) Department of Critical Care, Dalhousie University, Halifax, NS, Canada. jennifer.foster@dal.ca. (b) Department of Pediatric Critical Care, IWK Health, 5980 University Ave, Halifax, NS, B3K 6R8, Canada. jennifer.foster@dal.ca.
Conflicto:Declarations. Ethics approval and consent to participate: This study received ethics approval from IWK Health (REB#1026029). All research participants provided informed consent prior to participation in the study. Consent was reconfirmed at each opportunity for participant interfacing. Consent for publication: Informed consent included consent to publish non-identifying and aggregate data, including quotations. Competing interests: Neda Moghadam discloses that she is...
the co-chair of the Family Leadership Council of IWK Health. All other authors declare that they have no competing interests as defined by Springer, or other interests that might be perceived to influence the results and/or discussion reported in this paper.
Autor/es:Sconzo, Daniel (a) Enriquez-Marulanda, Alejandro (b)
institución:(a) Division of Neurosurgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. (b) Department of Neurosurgery, Boston Medical Center, Boston University Chobanian and Avedisian School of Medicine, 725 Albany St 7th Floor, Suite 7C, Boston, MA, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Association of sarcopenia and its prognostic value in symptomatic knee osteoarthritis among older people in China: the first longitudinal evidence from CHARLS.
Association of sarcopenia and its prognostic value in symptomatic knee osteoarthritis among older people in China: the first longitudinal evidence from CHARLS.
Fuente:Bmc Geriatrics
Extracto:
Sarcopenia was associated with a higher incident risk of symptomatic KOA, wherein
low muscle mass may play an important role. The inferior prognosis of sarcopenia
in KOA needs more attention in clinical practice.
Claves:Knee osteoarthritis, Nomogram, Possible sarcopenia, Prediction model, Sarcopenia
Early life circumstances and their impact on health in adulthood and later life
Early life circumstances and their impact on health in adulthood and later life
Fuente:Bmc Geriatrics
Tipo de trabajo:Revisión sistemática
Extracto:
FINAL CONSIDERATIONS: Understanding social
determinants, early-life adversities, and socioeconomic factors is essential for
promoting healthy and equitable aging, with effective interventions and public
policies aimed at reducing inequalities and ensuring the well-being of the adults
and older adults.
Claves:Age, Early Life adversities, Health disparities, Older adults, Public Health
institución:(a) Graduate Program in Physical Therapy, Federal University of Rio Grande do Norte (UFRN), Avenida Romualdo Galvão 2235, Lagoa Nova, Natal, RN, Brazil. weslleysaless8@gmail.com. (b) Graduate Program in Physical Therapy, Federal University of Rio Grande do Norte (UFRN), Avenida Romualdo Galvão 2235, Lagoa Nova, Natal, RN, Brazil.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Exosomes as novel biomarkers in sepsis and sepsis related organ failure.
Exosomes as novel biomarkers in sepsis and sepsis related organ failure.
Fuente:Journal of Translational Medicine
Extracto:
The combination of biomarker
development and sophisticated exosome detection techniques represents a
pioneering strategy in the realm of sepsis diagnosis and management, underscoring
the significance of further research and clinical validation.
Claves:Biomarker, Exosome, MiRNA, Organ failure, Sepsis
Cita:J Transl Med 2024 Nov 28; 22 (1) : 1078.
Autor/es:Yuan, Yixuan (a) Xiao, Yujie (b)
institución:(a) Department of Burns and Cutaneous Surgery, Xijing Hospital, Fourth Military Medical University, Chang-Le Xi Street #127, Xi'an, 710032, China. (b) Department of Burns and Cutaneous Surgery, Xijing Hospital, Fourth Military Medical University, Chang-Le Xi Street #127, Xi'an, 710032, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Fuente:The International Journal of Behavioral Nutrition and Physical Activity
Tipo de trabajo:Revisión sistemática
Extracto:
Findings should inform the design of future
physical activity interventions to ensure optimal effects on mental health
related outcomes. Additionally, if health professionals were to take these
mediators and moderators into consideration when prescribing or recommending
physical activity, physical activity would likely have a greater impact on
population mental health.
institución:(a) School of Health Sciences, Western Sydney University, Locked Bag 1797, Penrith, NSW, 2751, Australia. Rhiannon.White@westernsydney.edu.au. (b) Global Alliance of Mental Health and Sport, University of Wollongong, Wollongong, Australia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Recent novelties in research and management of cerebrospinal cavernous malformations.
Recent novelties in research and management of cerebrospinal cavernous malformations.
Fuente:Acta Neurochirurgica
Extracto:
Therefore, an up-to-date review of this field's latest
developments and controversies is reasonable.
Claves:Cavernous malformation, Central nervous system, Surgery, Treatment
Cita:Acta Neurochir (Wien) 2024 Nov 30; 166 (1) : 489.
Autor/es:Rauschenbach, Laurèl (a) Dammann, Philipp (b)
institución:(a) Department of Neurosurgery and Spine Surgery, University Hospital Essen, Essen, Germany. laurel.rauschenbach@uk-essen.de. (b) Center for Translational Neuroscience and Behavioral Science (C-TNBS), University of Duisburg-Essen, Essen, Germany. laurel.rauschenbach@uk-essen.de.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
VCAM-1(+) Mesenchymal Stem/Stromal Cells Reveal Preferable Efficacy Upon an Experimental Autoimmune Encephalomyelitis Mouse Model of Multiple Sclerosis Over the VCAM-1(-) Counterpart.
VCAM-1(+) Mesenchymal Stem/Stromal Cells Reveal Preferable Efficacy Upon an Experimental Autoimmune Encephalomyelitis Mouse Model of Multiple Sclerosis Over the VCAM-1(-) Counterpart.
Fuente:Neurochemical Research
Extracto:
Our findings indicated the feasibility of VCAM-1(+)
hUC-MSCs for multiple sclerosis treatment, which would supply new references for
the development of novel VCAM-1(+) MSCs-based cytotherapy in future.
institución:(a) Department of Neurology, The Second Hospital of Shandong University, 247 Beiyuan Road, Jinan, China. (b) Department of Neurology, Weihai Municipal Hospital, Weihai, China.
Conflicto:Declarations. Competing interest: The authors declare there’s no competing interests and all authors consent to publish the data. Ethical Approval: Ethical approval of this research was approved by the Institutional Animal Care and Use Committee of The Second Hospital of Shandong University (approval No.: KYLL-2023LW099) according to the International Guiding Principles for Biomedical Research Involving Animals. Consent to Participate: Not...
ot applicable.
Assessing the efficacy of different nano-iron sources for alleviating alkaline soil challenges in goji berry trees (Lycium barbarum L.).
Assessing the efficacy of different nano-iron sources for alleviating alkaline soil challenges in goji berry trees (Lycium barbarum L.).
Fuente:Bmc Plant Biology
Extracto:
Overall, these results highlight the
potential of green-synthesized nano-Fe as an efficient, cost-effective iron
source for improving vegetative growth, photosynthetic pigment levels, and
nutrient uptake in goji berries grown in alkaline soils.
Claves:Fe sources, Green- synthesis, Iron deficiency, Nano fertilizer, Photosynthetic pigments
Cita:BMC Plant Biol 2024 Nov 30; 24 (1) : 1153.
Autor/es:Ansari, Afsaneh (a) Amiri, Jafar (b)
institución:(a) Department of Horticultural Science, Faculty of Agriculture, Urmia University, Urmia, Iran. (b) Department of Horticultural Science, Faculty of Agriculture, Urmia University, Urmia, Iran. j.amiri@urmia.ac.ir.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Prevalence and psycho-social factors associated with alcohol use among primary school-going children aged 6 to 13 years in Mbale district, Uganda: a cross-sectional study.
Prevalence and psycho-social factors associated with alcohol use among primary school-going children aged 6 to 13 years in Mbale district, Uganda: a cross-sectional study.
Fuente:Bmc Pediatrics
Extracto:
The prevalence of alcohol consumption among
children in Mbale district, eastern Uganda was high with one-in-four
primary-school-children aged 6 to 13 years consuming alcohol in the past year,
and no significant gender differences. It highlights various interconnected
factors associated with alcohol use among school-aged children. We recommend
awareness campaigns at all levels, stricter implementation of alcohol policies,
school prevention programs, and family-focused and socio-economic interventions.
Nationwide school surveys should target pre-adolescent alcohol use.
institución:(a) Department of Psychiatry, Mulago National Referral and Teaching Hospital, Ministry of Health, Kampala, Uganda. joycenalugya@yahoo.com. (b) Department of Psychiatry, School of Medicine, Makerere University College of Health Sciences, Kampala, Uganda. joycenalugya@yahoo.com.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Are boys more vulnerable to stunting? Examining risk factors, differential sensitivity, and measurement issues in Zambian infants and young children.
Are boys more vulnerable to stunting? Examining risk factors, differential sensitivity, and measurement issues in Zambian infants and young children.
Fuente:Bmc Public Health
Extracto:
Our
results show that Zambian boys have lower mean HAZ scores than girls and a
greater prevalence of stunting throughout the first two years We do not find
strong evidence that infant feeding practices, environmental exposures, or care
giving differ consistently between boys and girls or that boys and girls respond
differently to these exposures. Our results instead indicate that further
investigation of prenatal factors and/or measurement issues is needed.
Claves:Growth standards, Infant and young child feeding, Sex difference, Stunting, Zambia
Cita:BMC Public Health 2024 Nov 29; 24 (1) : 3338.
Autor/es:Thompson, Amanda L (a) Onyango, Mathews (b)
institución:(a) Department of Anthropology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. althomps@email.unc.edu. (b) Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. althomps@email.unc.edu.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Comparing effectiveness of 3-needle approach versus 5-needle approach of genicular nerve block on pain and quality of life in chronic osteoarthritis of knee
Comparing effectiveness of 3-needle approach versus 5-needle approach of genicular nerve block on pain and quality of life in chronic osteoarthritis of knee
Fuente:Bmc Musculoskeletal Disorders
Tipo de trabajo:Estudio aleatorizado y controlado
Extracto:
The results revealed no significant difference between the groups; however, there
was a considerable decrease in pain and TUG test durations within the groups.
Consequently, neither strategy was better than the other. The group that received
GNB via a 5-point method had a superior QoL-KOOS at three months following the
procedure. TRIAL REGISTRATION: This study was registered in the Clinical Trials
Registry-India [CTRI/2023/06/054401] with registration date of 26/06/2023, after
approval was obtained from the Institutional Ethics Committee, All India
Institute of Medical Sciences, Jodhpur (Certificate Reference Number:
AIIMS/EIC/2022/4201) with a date of 23/09/2022.
Cita:BMC Musculoskelet Disord 2024 Nov 29; 25 (1) : 978.
Autor/es:Bhargava, Megha (a) Gaur, Ravi (b)
institución:(a) Department of Physical Medicine and Rehabilitation, All India Institute of Medical Sciences [AIIMS], Jodhpur, Rajasthan, India. meghabhargava@outlook.in. (b) Department of Physical Medicine and Rehabilitation, All India Institute of Medical Sciences [AIIMS], Jodhpur, Rajasthan, India. ravisms80@gmail.com.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
