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Blood pressure, gallstones, and age at first cholecystectomy in U.S. adults: a cross-sectional study.
Blood pressure, gallstones, and age at first cholecystectomy in U.S. adults: a cross-sectional study.
Fuente:Bmc Gastroenterology
Extracto:
The study found a correlation between BP and
the prevalence of gallstones in individuals aged 42 years and older and a
positive association between SBP and the age at first cholecystectomy. While
causality cannot be confirmed, these findings may assist in identifying early
risk groups for GD and early cholecystectomy, thereby enhancing risk
stratification and potentially reducing screening costs.
Claves:Cholecystectomy, Gallstones, Hypertension
Cita:BMC Gastroenterol 2025 Feb 7; 25 (1) : 65.
Autor/es:Zhang, Yue (a) Duan, Ruifeng (b)
institución:(a) Department of Gastroenterology and Digestive Endoscopy Center, The Second Hospital of Jilin University, Changchun, PR China. (b) Department of Gastroenterology and Digestive Endoscopy Center, The Second Hospital of Jilin University, Changchun, PR China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Extracto:
In addition, research should target nationwide
longitudinal heat vulnerability and examine the benefits of using HVI in heatwave
action plans.
institución:(a) School of Public Health, Faculty of Health, Medicine and Behavioural Sciences (HMBS), The University of Queensland, Brisbane, QLD, 4072, Australia. p.amoatey@uq.edu.au. (b) School of Medicine and Dentistry, Griffith University, Gold Coast, Queensland, Australia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Association of baseline and trajectory of triglyceride-glucose index with the incidence of cardiovascular autonomic neuropathy in type 2 diabetes mellitus.
Association of baseline and trajectory of triglyceride-glucose index with the incidence of cardiovascular autonomic neuropathy in type 2 diabetes mellitus.
Fuente:Cardiovascular Diabetology
Extracto:
Increased
baseline levels and long-term trajectory of TyG index are associated with an
increased incidence of CAN. Intensive glycemic therapy might influence the
association between the trajectory of TyG index and the chance of developing CAN.
Claves:Cardiovascular autonomic neuropathy, Diabetes, Trajectory, Triglyceride-glucose index
Cita:Cardiovasc Diabetol 2025 Feb 7; 24 (1) : 66.
Autor/es:Huang, Qiong (a) Nan, Wenbin (b)
institución:(a) Department of Metabolism and Endocrinology, Second Xiangya Hospital, Central South University, Changsha, 410011, China. (b) National Clinical Research Center for Metabolic Diseases, Key Laboratory of Diabetes Immunology, Department of Metabolism and Endocrinology, The Second Xiangya Hospital, Ministry of Education, Central South University, Changsha, 410011, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Correspondence: insulin resistance and chronic kidney disease in patients without diabetes.
Correspondence: insulin resistance and chronic kidney disease in patients without diabetes.
Fuente:Bmc Nephrology
Extracto:
When investigating the CKD diagnostic
performance of HOMA-IR, its cut-off for clinically meaningful insulin resistance
should be well justified or comprehensively explored to improve the reliability
of the results.
Autor/es:Pham, Hong Tham (a) Truong-Nguyen, Kim-Huong (b)
institución:(a) Faculty of Pharmacy, Nguyen Tat Thanh University, Ho Chi Minh City, Vietnam. (b) Department of Pharmacy, Nhan Dan Gia Dinh Hospital, Ho Chi Minh City, Vietnam.
Conflicto:Declarations. Ethics approval and consent to participate: Not applicable. Consent for publication: Not applicable. Competing interests: HTP reported receiving speaking fees and travel reimbursement from Servier Vietnam Ltd and Pfizer Vietnam Ltd, grants from Servier Vietnam Ltd, and speaking fees from Aguettant Asia Pacific Pte Ltd outside the submitted work. K-HT-N reported receiving travel reimbursement from Pierre Fabre Vietnam Ltd...
outside the submitted work. M-HT reported receiving travel reimbursement from Pfizer Vietnam Ltd and Viatris Vietnam Ltd, speaking fees and grants from Servier Vietnam Ltd, and speaking fees from Aguettant Asia Pacific Pte Ltd outside the submitted work. Registry, trial registration number, and data of registration: Not applicable. Clinical trial number: Not applicable.
The protective role of SGLT2 inhibitors on aortic aneurysm mediated by oxidative stress and inflammation in type 2 diabetes mellitus.
The protective role of SGLT2 inhibitors on aortic aneurysm mediated by oxidative stress and inflammation in type 2 diabetes mellitus.
Fuente:Cardiovascular Diabetology
Extracto:
Our study suggested that patients using SGLT2i
may have a lower risk of aortic aneurysm, and this effect could potentially be
mediated by inflammation and oxidative stress. Further mechanistic and
prospective studies are required to verify this association.
institución:(a) The First Central Clinical School, Tianjin Medical University, Tianjin, China. (b) The First Central Clinical School, Tianjin Medical University, Tianjin, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
The synergistic effect of the triglyceride-glucose index and a body shape index on cardiovascular mortality: the construction of a novel cardiovascular risk marker.
The synergistic effect of the triglyceride-glucose index and a body shape index on cardiovascular mortality: the construction of a novel cardiovascular risk marker.
Fuente:Cardiovascular Diabetology
Extracto:
The simultaneous assessment of the TyG index and ABSI revealed a synergistic
effect on cardiovascular mortality. We recommended the use of TyG-ABSI instead of
the TyG index and other modified TyG indices in cardiovascular risk assessment.
Claves:A body shape index, Arterial stiffness, Cardiovascular mortality, NHANES, Triglyceride-glucose index
Cita:Cardiovasc Diabetol 2025 Feb 7; 24 (1) : 69.
Autor/es:He, Hao-Ming (a) Xie, Ying-Ying (b)
institución:(a) China-Japan Friendship Hospital (Institute of Clinical Medical Sciences), Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China. (b) Department of Cardiology, China-Japan Friendship Hospital, No. 2 East Yinghua Road, Chaoyang District, Beijing, 100029, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Predicting cardiovascular outcomes in Chinese patients with type 2 diabetes by combining risk factor trajectories and machine learning algorithm
Predicting cardiovascular outcomes in Chinese patients with type 2 diabetes by combining risk factor trajectories and machine learning algorithm
Fuente:Cardiovascular Diabetology
Tipo de trabajo:Estudio de cohortes
Extracto:
The ML-CVD-C model, incorporating
dynamic cardiovascular risk trajectories and a machine learning algorithm,
significantly improves risk prediction accuracy for Chinese patients with
diabetes. This model may serve as a valuable tool for more personalized
cardiovascular risk management in type 2 diabetes.
Claves:Machine learning, Risk prediction, Trajectories, Type 2 diabetes
Cita:Cardiovasc Diabetol 2025 Feb 7; 24 (1) : 61.
Autor/es:Huang, Qi (a) Zou, Xiantong (b)
institución:(a) Department of Endocrinology and Metabolism, Peking University People's Hospital, Beijing, 100044, China. (b) Department of Endocrinology and Metabolism, Peking University People's Hospital, Beijing, 100044, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Baseline atherogenic index of plasma and its trajectory predict onset of type 2 diabetes in a health screened adult population: a large longitudinal study.
Baseline atherogenic index of plasma and its trajectory predict onset of type 2 diabetes in a health screened adult population: a large longitudinal study.
Fuente:Cardiovascular Diabetology
Tipo de trabajo:Estudio de cohortes
Extracto:
Elevated baseline AIP levels, medium stable
trajectories and high stable trajectories are associated with an increased risk
of T2DM in health screened adults.
Defining patient-reported outcomes in diabetes, obesity, cardiovascular disease, and chronic kidney disease for clinical practice guidelines - perspectives of the taskforce of the Guideline Workshop.
Defining patient-reported outcomes in diabetes, obesity, cardiovascular disease, and chronic kidney disease for clinical practice guidelines - perspectives of the taskforce of the Guideline Workshop.
Fuente:Cardiovascular Diabetology
Extracto:
The Taskforce of the Guideline Workshop discussed PROs
in diabetes, obesity, CVD and CKD as well as the relevance of their inclusion in
clinical practice guidelines for the management of these conditions.
institución:(a) Southern Health NHS Foundation Trust, Southampton, UK. (b) Spotlight-AQ Ltd, Fareham, UK.
Conflicto:Declarations. Ethics approval and consent to participate: Not applicable. Consent for publication: Not applicable. Competing interests: Katharine Barnard-Kelly is founder and shareholder at Spotlight-AQ Ltd. KBK has received research support from Dexcom, Embecta, JDRF, Novo Nordisk and Roche Diabetes Care, and honoraria from Sanofi. Tadej Battelino has served on the advisory boards of Abbott, Boehringer Ingelheim, Dreamed Diabetes, Eli Lilly...
and Company, Indigo Diabetes, Medtronic, Novo Nordisk, and Sanofi. TB has received speaker’s bureau honoraria from Abbott, Eli Lilly and Company, Medtronic, Novo Nordisk, Roche, and Sanofi. The University Medical Center has received research grant support from Abbott, GluSense, Medtronic, Novo Nordisk, Sandoz, Sanofi, and Zealand Pharma. Frank C. Brosius is a consultant for MAKSCIENTIFIC. Antonio Ceriello reports consulting and speaking for Bayer, Berlin-Chemie, Eli Lilly and Company, Guidotti, Merck, Novo Nordisk, Roche Diagnostics and Sanofi. Francesco Cosentino has nothing reported. Julian Elliott has nothing reported. James R. Gavin III has served on the advisory boards of Abbott Diabetes Care and Embecta, and on the speaker’s bureaus of Boehringer Ingelheim and Eli Lilly and Company. Francesco Giorgino has served on the advisory boards of AstraZeneca, Eli Lilly and Company, Novo Nordisk, Roche Diabetes Care, Sanofi and as a consultant to AstraZeneca, Boehringer Ingelheim, LifeScan, Medimmune, Medtronic, Merck Sharp & Dohme, Roche Diabetes Care and Sanofi. FG has also received research support from Eli Lilly and Company and Roche Diabetes Care. Jennifer Green has nothing reported. Linong Ji declares that he has no competing interests. Monika Kellerer has served on advisory boards of Abbott Diabetes Care, Astra Zeneca, Bayer AG, Boehringer-Ingelheim, Eli Lilly, NovoNordisk and Sanofi. Sue Koob has nothing reported. Mikhail Kosiborod reports consulting or advisory board participation for 35Pharma, Alnylam Pharmaceuticals, Amgen, Applied Therapeutics, AstraZeneca, Bayer, Boehringer Ingelheim, Cytokinetics, Dexcom, Eli Lilly and Company, Esperion Therapeutics, Janssen Pharmaceuticals, Lexicon Pharmaceuticals, Merck (Diabetes and Cardiovascular), Novo Nordisk, Pharmacosmos, Pfizer, scPharmaceuticals, Sanofi, Structure Therapeutics, Vifor Pharma and Youngene Therapeutics. MK has also received honoraria from AstraZeneca, Boehringer Ingelheim and Novo Nordisk, and research grants from AstraZeneca, Boehringer Ingelheim and Pfizer. Nebojsa Lalic declares that he has no competing interests. Nikolaus Marx has received research grants from Boehringer Ingelheim and MSD, speaking fees form Amgen, AstraZeneca, Bayer, BMS, Boehringer Ingelheim, Eli Lilly and Company, MSD, Novo Nordisk, and Sanofi-Aventis and has served or serves on the advisory board of Amgen, Bayer, BMS, Boehringer Ingelheim, MSD, Novo Nordisk, and Sanofi-Aventis. Prashant Nedungadi has nothing reported. Christopher G. Parkin has nothing reported. Helena W. Rodbard declares that she has no competing interests. René D. Rötzer is employee of Sciarc GmbH. Lars Rydén declares that he has no competing interests related to this work. Wayne Sheu has nothing reported. Eberhard Standl declares that he has no competing interests. Britta Tendal Jeppesen declares that she has no competing interests. Pinar Topsever has received honoraria or consulting fees from AstraZeneca, Boehringer Ingelheim, Eli Lilly and Company, and LifeScan, and has served on the speaker’s bureau for AstraZeneca. PT received grant/research support from PCDE, made possible by corporate sponsorship from AstraZeneca, Eli Lilly, Novo Nordisk, and Roche Diagnostics; the sponsors had no input into the study protocols. Per Olav Vandvik has nothing reported. Christoph Wanner received honoraria for steering committee and adboard participation as well as lecturing from Alexion, AstraZeneca, Bayer, Boehringer Ingelheim, Eli-Lilly, MSD, Novo Nordisk and Sanofi. Oliver Schnell is founder and CEO at Sciarc GmbH, Baierbrunn, Germany.
A sex-disaggregated analysis of the prognostic value of lean type 2 diabetes mellitus in the adult population with acute myocardial infarction.
A sex-disaggregated analysis of the prognostic value of lean type 2 diabetes mellitus in the adult population with acute myocardial infarction.
Fuente:Cardiovascular Diabetology
Extracto:
The lean T2DM phenotype was present in one-quarter of
the AMI cohort with T2DM. The lean T2DM phenotype was an independent predictor of
long-term mortality following AMI, although this association was stronger in
males than in females.
Claves:Acute myocardial infarction, Cardiovascular outcomes, Lean, Sex differences, Type 2 diabetes mellitus
Cita:Cardiovasc Diabetol 2025 Feb 7; 24 (1) : 59.
Autor/es:Kong, Gwyneth (a) Koh, Jaycie (b)
institución:(a) Department of Medicine, National University Hospital, Singapore, Singapore. (b) Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Conflicto:Declarations. Ethics approval and consent to participate: The study was approved by the local institutional review committee in accordance with the revised Declaration of Helsinki (NHG Research—DSRB: 2021/00089-AMD0001). The institutional review board waived the need for written patient consent as this study involved a retrospective analysis of clinically acquired data. Consent for publication: Not applicable. This manuscript does not contain...
in any individual person’s data in any form. Competing interests: M.Y.C. receives speaker’s fees and research grants from Astra Zeneca, Abbott Technologies and Boston Scientific. N.W.S.C has received research grant support from NUHS Seed Fund (NUHSRO/2022/RO5+6/Seed-Mar/03), National Medical Research Council Research Training Fellowship (MH 095:003/008-303), National University of Singapore Yong Loo Lin School of Medicine’s Academic Fellowship Scheme, and the NUHS Clinician Scientist Program (NCSP2.0/2024/NUHS/NCWS).
Cardiac magnetic resonance quantified epicardial fat volume is associated with complex coronary artery disease among diabetics.
Cardiac magnetic resonance quantified epicardial fat volume is associated with complex coronary artery disease among diabetics.
Fuente:Cardiovascular Diabetology
Extracto:
Increased epicardial adipose tissue
was a significant independent predictor of severe and complex CAD, representing a
possible risk marker and potential therapeutic target, particularly among
diabetics.
institución:(a) Department of Cardiovascular Medicine, Assiut University Heart Hospital, Assiut, 71526, Egypt. shaimaakhidr@gmail.com. (b) Department of Cardiovascular Medicine, Assiut University Heart Hospital, Assiut, 71526, Egypt.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Assessment of stress hyperglycemia ratio to predict all-cause mortality in patients with critical cerebrovascular disease
Assessment of stress hyperglycemia ratio to predict all-cause mortality in patients with critical cerebrovascular disease
Fuente:Cardiovascular Diabetology
Tipo de trabajo:Estudio de cohortes
Extracto:
SHR serves as an
independent risk factor for in-hospital mortality in cerebrovascular disease
patients in the ICU. Adding SHR to existing models enhances their predictive
performance, offering clinical value in the identification of high-risk patients.
Claves:Cerebrovascular disease, Intensive care unit, Mortality, Stress hyperglycemia ratio
Cita:Cardiovasc Diabetol 2025 Feb 7; 24 (1) : 58.
Autor/es:Chen, Yuwen (a) Xu, Jian (b)
institución:(a) Department of Cardiology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. (b) State Key Laboratory of Transvascular Implantation Devices, Hangzhou, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Modulating the developing gut microbiota with 2'-fucosyllactose and pooled human milk oligosaccharides.
Modulating the developing gut microbiota with 2'-fucosyllactose and pooled human milk oligosaccharides.
Fuente:Microbiome
Extracto:
Our study provides valuable
insight into the health-enhancing properties of HMOs while highlighting the need
for future research into the efficacy of incorporating individual structures into
infant formula, particularly when aiming to modulate the gut microbiota. Video
Abstract.
Claves:2’-fucosyllactose, Child gut microbiota, Developing gut microbiota, Human milk, Human milk oligosaccharides, Metabolomics
Cita:Microbiome 2025 Feb 7; 13 (1) : 44.
Autor/es:Renwick, Simone (a) Furst, Annalee (b)
institución:(a) Family Larsson-Rosenquist Foundation Mother-Milk-Infant Center of Research Excellence (MOMI CORE), the Human Milk Institute (HMI), Department of Pediatrics, School of Medicine, University of California San Diego, La Jolla, CA, USA. (b) Family Larsson-Rosenquist Foundation Mother-Milk-Infant Center of Research Excellence (MOMI CORE), the Human Milk Institute (HMI), Department of Pediatrics, School of Medicine, University of California San Diego, La Jolla, CA, USA.
Conflicto:Declarations. Ethics approval and consent to participate: Selected fecal samples from the DIABIMMUNE sample database were shipped to the Allen-Vercoe lab following secondary site approval for culture and analysis by the University of Guelph Research Ethics Board, project REB#17-06-006. Consent for publication: Not applicable. Competing interests: E.A.-V. is a co-founder of Nubiyota, a company focused on the human gut microbiome....
L.B. is a co-inventor on patent applications related to the use of HMOs in preventing NEC and other inflammatory diseases. S.R., A.F., M.K. and J.D. declare that they have no competing interests.
institución:(a) Nephrology Department, Central Theater Command General Hospital of the Chinese People's Liberation Army, No.627, Wuluolu, Wuchang District, Wuhan, 430070, Hubei, China. 30832644@qq.com. (b) Nephrology Department, Central Theater Command General Hospital of the Chinese People's Liberation Army, No.627, Wuluolu, Wuchang District, Wuhan, 430070, Hubei, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Challenges in the diagnosis of heart failure with preserved ejection fraction in individuals with obesity.
Challenges in the diagnosis of heart failure with preserved ejection fraction in individuals with obesity.
Fuente:Cardiovascular Diabetology
Extracto:
In this review,
we examine these diagnostic challenges and propose a diagnostic algorithm
specifically tailored to improve the accuracy and reliability of HFpEF diagnosis
in this growing patient demographic.
institución:(a) Thorax Center, Department of Cardiology, Cardiovascular Institute, Erasmus MC, Rotterdam, The Netherlands. b.vandalen@franciscus.nl. (b) Department of Cardiology, Franciscus Gasthuis & Vlietland, Kleiweg 500, Rotterdam, 3045 PM, The Netherlands. b.vandalen@franciscus.nl.
Conflicto:Declarations. Competing interests: The institution of Dr. De Boer has received research grants and/or fees from Alnylam, AstraZeneca, Abbott, Bristol-Myers Squibb, Cardior Pharmaceuticals GmbH, NovoNordisk, and Roche; Dr. de Boer has had speaker engagements with and/or received fees from and/or served on an advisory board for Abbott, AstraZeneca, Bristol Myers Squibb, Cardior Pharmaceuticals GmbH, NovoNordisk, and Roche; Dr. de Boer...
received travel support from Abbott, Cardior Pharmaceuticals GmbH, and NovoNordisk. Dr Brugts reports speaker engagements and/or advisory to Astra Zeneca, Abbott, Bayer, Boehringer Ingelheim, Novartis and Vifor outside the submitted work (3 year period). The institution of Dr. Van Dalen received research grants from Biotronik SE & Co. KG, Boehringer Ingelheim, Pfizer, Daiichi Sankyo, Sanofi and Novo Nordisk.
institución:(a) Applied Sports Technology, Exercise and Medicine (A-STEM) Research Centre, Faculty of Science and Engineering, Swansea University, Swansea, UK. (b) Diabetes Research Group, Grove Building, Swansea University, Swansea, UK.
Waist-to-hip ratio better reflect beta-cell function and predicts diabetes risk in adult with overweight or obesity.
Waist-to-hip ratio better reflect beta-cell function and predicts diabetes risk in adult with overweight or obesity.
Fuente:Annals of Medicine
Extracto:
WHpR is a superior index in reflecting central body
obesity, estimating beta cell function, and predicting T2D risk in people with
overweight or obesity compared to BMI, WC, and WHtR.
institución:(a) Department of Endocrinology, Xiangya Hospital, Central South University, Changsha, Hunan, China. (b) Hunan Engineering Research Center for Obesity and Its Metabolic Complications, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Conflicto:No potential conflict of interest was reported by the author(s).
Instruments for assessing patient-reported experience measures among patients with diabetes mellitus
Instruments for assessing patient-reported experience measures among patients with diabetes mellitus
Fuente:Journal of Patient-reported Outcomes
Tipo de trabajo:Revisión
Extracto:
This scoping review identifies a limited number
of tools for evaluating PREMs in diabetes care, highlighting variability in their
development and domain coverage. Five core domains are proposed across different
settings, with an emphasis on culturally adapted measures to enhance the accuracy
of patient experience capture in diverse populations.
Claves:Diabetes mellitus, Patient outcome assessment, Patient-centered care, Patient-reported experience measures
institución:(a) Global Health and Chronic Conditions Research Center, Chiang Mai University, Chiang Mai, 50200, Thailand. (b) Department of Family Medicine, Faculty of Medicine, Chiang Mai University, 110 Inthawarorot Rd., Sriphum, Muang, Chiang Mai, 50200, Thailand.
Conflicto:Declarations. Ethics approval and consent to participate: This is a scoping review of available literature; no ethical approval and consent to participant was required from the Institutional Review Board. Consent for publication: Not applicable. Competing interests: The authors have no relevant financial or non-financial interests to disclose.
An ontology-based rare disease common data model harmonising international registries, FHIR, and Phenopackets.
An ontology-based rare disease common data model harmonising international registries, FHIR, and Phenopackets.
Fuente:Scientific Data
Extracto:
We identified three categories for evaluation:
Medical Data Granularity, Clinical Reasoning and Medical Relevance, and
Interoperability and Harmonisation.
Cita:Sci Data 2025 Feb 8; 12 (1) : 234.
Autor/es:Graefe, Adam S L (a) Hübner, Miriam R (b)
institución:(a) Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany. adam.graefe@charite.de. (b) Institute for Biomedical Informatics, University Hospital Cologne, Cologne, Germany. adam.graefe@charite.de.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Hemoglobin mediates the link between the 'weekend warrior' physical activity pattern and diabetic retinopathy.
Hemoglobin mediates the link between the 'weekend warrior' physical activity pattern and diabetic retinopathy.
Fuente:Scientific Reports
Extracto:
In comparison, the WW PA pattern is
the most cost effective for DR prevention.
Cita:Sci Rep 2025 Feb 8; 15 (1) : 4774.
Autor/es:Li, Baohua (a) Ning, Bobiao (b)
institución:(a) China Academy of Chinese Medical Sciences Eye Hospital, No.33 Lu-Gu Road, Shijingshan District 100040, Beijing, People's Republic of China. (b) China Academy of Chinese Medical Sciences Guang'anmen Hospital, No. 138, Section 2, Huangcun Xingfeng Street, Daxing District 102600, Beijing, People's Republic of China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
