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Associations between neutrophil percentage to albumin ratio and rheumatoid arthritis versus osteoarthritis: a comprehensive analysis utilizing the NHANES database.
Associations between neutrophil percentage to albumin ratio and rheumatoid arthritis versus osteoarthritis: a comprehensive analysis utilizing the NHANES database.
Fuente:Frontiers in Immunology
Extracto:
High levels of NPAR is positively
associated with the prevalence of RA. This provides us with new insights for the
management and treatment of RA patients.
Claves:National Health and Nutrition Examination Survey, cross-sectional study, inflammation, neutrophil percentage to albumin ratio, osteoarthritis, rheumatoid arthritis
Cita:Front Immunol 2025; 16 : 1436311.
Autor/es:Ding, Wenquan (a) La, Rui (b)
institución:(a) Department of Orthopedic Surgery, Orthopedic Institute, The First Affiliated Hospital of Soochow University, Soochow, Jiangsu, China. (b) Department of Orthopedic Surgery, Orthopedic Institute, The First Affiliated Hospital of Soochow University, Soochow, Jiangsu, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Effects of practical models of low-volume high-intensity interval training on glycemic control and insulin resistance in adults
Effects of practical models of low-volume high-intensity interval training on glycemic control and insulin resistance in adults
Fuente:Frontiers in Endocrinology
Tipo de trabajo:Revisión sistemática
Extracto:
Conclusively, a
practical model of LV-HIIT with reduced intensity and extended interval was
effective in improving glucose control and its effects were similar to MICT.
Greater improvements were found in individuals with overweight/obesity or T2D in
protocols with longer intervals or accumulated interval duration per
session/week. More large-scale, randomized controlled studies with similar
intervention protocols in a wide range of population are warranted to confirm
these important results. SYSTEMATIC REVIEW REGISTRATION:
https://www.crd.york.ac.uk/prospero/, identifier CRD42024516594.
Claves:glucose, high-intensity interval training, insulin resistance, low-volume, practical model
institución:(a) Faculty of Sports Science, Ningbo University, Ningbo, China. (b) Centre for Population Health and Medical Informatics, Department of Sport, Physical Education and Health, Hong Kong Baptist University, Hong Kong, Hong Kong SAR, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.
The role of activated partial thrombin time in mediating the impact of poorly glycemic control on diabetic peripheral neuropathy in patients with type 2 diabetes mellitus.
The role of activated partial thrombin time in mediating the impact of poorly glycemic control on diabetic peripheral neuropathy in patients with type 2 diabetes mellitus.
Fuente:Frontiers in Endocrinology
Extracto:
In patients with
T2DM, uncontrolled HbA1c and shorter APTT emerges as risk factors for DPN.
Additionally, the effect of increased HbA1c upon DPN, especially for influenced
conduction velocities of sensory fibers in both the ulnar nerve and sural nerve
may partly medicated by decreased APTT.
Claves:activated partial thrombin time, diabetic peripheral neuropathy, hyperglycemia, nerve conduction velocity, type 2 diabetes mellitus
institución:(a) Henan Key Laboratory of Rare Diseases, Endocrinology and Metabolism Center, The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, China. (b) Department of Endocrinology, Institute of Endocrine and Metabolic Diseases, Centre for Leading Medicine and Advanced Technologies of IHM, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Perioperative Factor Xa Inhibitor Discontinuation for Patients Undergoing Procedures With Minimal or Low Bleeding Risk.
Perioperative Factor Xa Inhibitor Discontinuation for Patients Undergoing Procedures With Minimal or Low Bleeding Risk.
Fuente:Jama Network Open
Tipo de trabajo:Estudio de cohortes
Extracto:
AND RELEVANCE: In
this cohort study, patients with AF receiving a factor Xa inhibitor and
undergoing a procedure with minimal to low bleeding risk had low rates of major
bleeding and thromboembolism when following the standardized PERIXa protocol for
perioperative management of oral anticoagulant treatment, suggesting that this
may be a safe and reasonable option for this patient population.
Cita:JAMA Netw Open 2025 Feb 3; 8 (2) : e2458742.
Autor/es:Lee, So-Ryoung (a) Lee, Kyung-Yeon (b)
institución:(a) Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea. (b) Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
Conflicto:Conflict of Interest Disclosures: Dr Lip reported receiving consultant and speaker fees from Anthos, BMS/Pfizer, Boehringer Ingelheim, and Daiichi-Sankyo outside the submitted work. Dr Choi reported receiving grants from Abbott, Bayer, BMS/Pfizer, Biosense Webster, Chong Kun Dang, Daewoong Pharmaceutical, Daiichi-Sankyo, DeepQure, Dreamtech, Jeil Pharmaceutical, Medtronic, Samsung Electronics, Seers Technology, and Skylabs during the conduct of the study and receiving personal...
fees from Abbott, Bayer, BMS/Pfizer, Biosense Webster, Chong Kun Dang, Daewoong Pharmaceutical, Daiichi-Sankyo, DeepQure, Dreamtech, Jeil Pharmaceutical, Medtronic, Samsung Electronics, Seers Technology, and Skylabs outside the submitted work. No other disclosures were reported.
Industry Payments and Sentiments Toward Robotic Surgery Among US Physicians.
Industry Payments and Sentiments Toward Robotic Surgery Among US Physicians.
Fuente:Jama Network Open
Tipo de trabajo:Estudio de cohortes
Extracto:
AND RELEVANCE: In this cohort study of US-based
physicians, publicly available social media data were used to quantify
perceptions of robotic surgery. These findings demonstrate the potential of such
data to inform health care practices, guide balanced information dissemination,
and uphold the integrity of health information shared by physicians.
Cita:JAMA Netw Open 2025 Feb 3; 8 (2) : e2458552.
Autor/es:Loh, Wei San (a) Ibrahim, Andrew M (b)
institución:(a) Center for Healthcare Outcomes & Policy, University of Michigan, Ann Arbor. (b) Center for Healthcare Outcomes & Policy, University of Michigan, Ann Arbor.
Conflicto:Conflict of Interest Disclosures: Dr Sheetz reported receiving grants from the National Institute of Diabetes and Digestive and Kidney Diseases during the conduct of the study. No other disclosures were reported.
Effectiveness of Continuous Glucose Monitoring on Short-Term, In-Hospital Mortality Among Frail and Critically Ill Patients With COVID-19: Randomized Controlled Trial.
Effectiveness of Continuous Glucose Monitoring on Short-Term, In-Hospital Mortality Among Frail and Critically Ill Patients With COVID-19: Randomized Controlled Trial.
Fuente:Journal of Medical Internet Research
Tipo de trabajo:Estudio aleatorizado y controlado
Extracto:
We found a
significant clinical benefit from the use of CGM among frail and critically ill
patients with COVID-19. These findings support the use of CGM in the ICU and
might help with the extension of application in various in-hospital settings.
TRIAL REGISTRATION: Chinese Clinical Trial Registry ChiCTR2200059733;
https://www.chictr.org.cn/showproj.html?proj=169257.
Claves:CGM, COVID-19, ICU, POCT, SARS-CoV-2, clinical trial, continuous glucose monitoring, critically ill, exploratory, frail, glucose monitoring, in-ICU mortality, in-hospital mortality, inpatient mortality, intensive care unit, intermittently scanned continuous glucose monitoring, isCGM, mortality, open label, parallel, point of care testing, prospective, randomized, single center
Cita:J Med Internet Res 2025 Feb 7; 27 : e67012.
Autor/es:Shang, Jiawei (a) Yuan, Ziming (b)
institución:(a) Department of Intensive Care Medicine, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. (b) Department of Intensive Care Medicine, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Racial and ethnic disparities in longitudinal trajectories of cardiovascular risk factors in U.S. middle-aged and older adults.
Racial and ethnic disparities in longitudinal trajectories of cardiovascular risk factors in U.S. middle-aged and older adults.
Fuente:Plos One
Extracto:
Significant racial and ethnic disparities
were observed in trajectories of CVD risk factors in U.S. adults. Social
determinants largely contributed to these associations in non-Hispanic Black
adults and Hispanic adults.
Cita:PLoS One 2025; 20 (2) : e0318419.
Autor/es:Dupre, Matthew E (a) Dhingra, Radha (b)
institución:(a) Department of Population Health Sciences, Duke University, Durham, NC, United States of America. (b) Department of Sociology, Duke University, Durham, NC, United States of America.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Health-related quality of life and its predictors among chronic kidney disease patients: A hospital-based cross-sectional study.
Health-related quality of life and its predictors among chronic kidney disease patients: A hospital-based cross-sectional study.
Fuente:Plos One
Extracto:
By
addressing the determinants of poor HRQoL, healthcare providers can tailor
treatment plans to better meet the needs of these individuals and ultimately
enhance their overall well-being.
Cita:PLoS One 2025; 20 (2) : e0319100.
Autor/es:Tasnim, Tasmia (a) Karim, Kazi Muhammad Rezaul (b)
institución:(a) Department of Nutrition and Food Engineering, Daffodil International University, Daffodil Smart City, Birulia, Savar, Dhaka, Bangladesh. (b) Institute of Nutrition and Food Science, University of Dhaka, Dhaka, Bangladesh.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
A qualitative exploration of the educational needs of people living with heart failure: BANDAIDD-Explore study.
A qualitative exploration of the educational needs of people living with heart failure: BANDAIDD-Explore study.
Fuente:Plos One
Extracto:
Priorities for education improvement were also provided,
including regional and rural considerations; engaging informal family caregivers;
tailoring to culturally and linguistically diverse and indigenous peoples,
navigating the health system and ensuring continuity of care.
Cita:PLoS One 2025; 20 (2) : e0314059.
Autor/es:Ferguson, Caleb (a) William, Scott (b)
institución:(a) Centre for Chronic & Complex Care Research, Blacktown Hospital, Western Sydney Local Health District, & School of Nursing, University of Wollongong, Wollongong, Australia. (b) Centre for Chronic & Complex Care Research, Blacktown Hospital, Western Sydney Local Health District, & School of Nursing, University of Wollongong, Wollongong, Australia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Efficacy and safety of dexamethasone or triamcinolone in combination with anti-vascular endothelial growth factor therapy for diabetic macular edema
Efficacy and safety of dexamethasone or triamcinolone in combination with anti-vascular endothelial growth factor therapy for diabetic macular edema
Fuente:Plos One
Tipo de trabajo:Revisión sistemática
Extracto:
Our study confirmed that dexamethasone
or triamcinolone plus anti-VEGF therapy did not show superior efficacy in
improving BCVA and reducing CMT in DME patients compared with anti-VEGF
monotherapy. Clinicians should weigh the pros and cons comprehensively when
implementing combined therapy.
The effect of SGLT2 inhibitor in patients with type 2 diabetes and atrial fibrillation.
The effect of SGLT2 inhibitor in patients with type 2 diabetes and atrial fibrillation.
Fuente:Plos One
Extracto:
In a nationwide cohort of patients with T2D and AF, SGLT2
inhibitor was associated with a lower risk of mortality, which may suggest that
SGLT2 inhibitors may be considered as the first-line antidiabetic medication in
patients with T2D and AF.
Cita:PLoS One 2025; 20 (2) : e0314454.
Autor/es:Cho, Yongin (a) Shin, Sung-Hee (b)
institución:(a) Department of Endocrinology and Metabolism, Inha University College of Medicine, Incheon, Republic of Korea. (b) Department of Cardiology, Inha University College of Medicine, Incheon, Republic of Korea.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Advanced retinal disease detection from OCT images using a hybrid squeeze and excitation enhanced model.
Advanced retinal disease detection from OCT images using a hybrid squeeze and excitation enhanced model.
Fuente:Plos One
Extracto:
These findings emphasize the model's ability to effectively diagnose
retinal disorders using OCT images and indicate substantial promise for the
development of computer-aided diagnostic tools in the field of ophthalmology.
Cita:PLoS One 2025; 20 (2) : e0318657.
Autor/es:Gencer, Gülcan (a) Gencer, Kerem (b)
institución:(a) Department of Biostatistics and Medical Informatics, Faculty of Medicine, Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey. (b) Department of Computer Engineering, Faculty of Engineering, Afyon Kocatepe University, Afyonkarahisar, Turkey.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Evidence-informed language: interpretation and impact on intentions to treat - results of an online survey of medical students and specialists in German-speaking countries.
Evidence-informed language: interpretation and impact on intentions to treat - results of an online survey of medical students and specialists in German-speaking countries.
Fuente:Bmj Open
Tipo de trabajo:Consenso
Extracto:
This study demonstrates limitations in the
currently used linguistic expressions of strength of evidence and clinical
practice recommendations and supports the need to prospectively test effects of
language on intentions to treat prior to implementation of a certain wording.
Study results cast doubt on that linguistic means alone will lead to optimally
targeted intentions to treat.
Claves:Clinical Decision-Making, Clinical Reasoning, MEDICAL EDUCATION & TRAINING
institución:(a) European Cardiology Section Foundation, Cologne, Germany. (b) Institute for Medical Education, Centre for Translational Neuro- and Behavioral Sciences (C-TNBS), University Hospital Essen, Essen, Germany.
Conflicto:Competing interests: RG declares the following non-financial competing interests: Praxis Rheingalerie, Cologne, Germany (2017-); Assistant Medical Director and Head of Training, Department of Cardiology, Angiology and Diabetology, Municipal Hospital Cologne (Merheim), University of Cologne, Germany (-2017); Chairman of the Board, European Cardiology Section Foundation, Cologne, Germany (2010-); Chairman, Advisory Committee European Board for Accreditation of Continuing Education for Health Professionals...
(EBAC), Cologne, Germany (2010-2018); Head, Academy for Training and Education, Chamber of Physicians North-Rhine, Duesseldorf, Germany (2000–2020); Member of the Board, Chamber of Physicians North-Rhine, Duesseldorf, Germany (2005–2019); Member, Standing Committee for CME, German Medical Association, Berlin, Germany (-2020); Member, Committee for Training and Education Politics, Marburger Bund Germany, Berlin, Germany (-2023); Member, Education Committee, German Cardiac Society; Member, Editorial Board, Journal of CME (JCME). JS declares no competing interests. HH declares following as non-financial competing interests: Medical Director, Vocational Training Center, Westküstenklinikum Heide, Heide, Germany; Professor for Physician Assistants, SRH University of Health, Gera, Germany; Former Head of Department, Internal Medicine and Geriatrics, Westküstenklinikum Brunsbüttel, Brunsbüttel, Germany; President, Chamber of Physicians Schleswig-Holstein, Bad Segeberg, Germany; Member of the Board, German Medical Association, Berlin, Germany; Co-Chairman, Education Committee, German Medical Association, Member of the Board, Marburger Bund Germany, Berlin, Germany; Co-Chairman, Committee for Training and Education Politics, Marburger Bund Germany; Chairman, ECSF Council, Cologne, Germany. SB received speaker honoraria from AstraZeneca; Bayer AG; Celgene; Grünenthal AG Switzerland; Grünenthal; Janssen-Cilag; Lilly Deutschland; Novo Nordisk Pharma; Sanofi-Aventis Deutschland; Symbiopharm and Urgo outside the present study and is Director of the Institute of Medical Education, University Duisburg-Essen, Germany (2021-).
Personalized prediction of glycemic responses to food in women with diet-treated gestational diabetes: the role of the gut microbiota.
Personalized prediction of glycemic responses to food in women with diet-treated gestational diabetes: the role of the gut microbiota.
Fuente:Npj Biofilms and Microbiomes
Extracto:
Although
microbiome features were important, their contribution to model performance was
modest.
Cita:NPJ Biofilms Microbiomes 2025 Feb 7; 11 (1) : 25.
Autor/es:Popova, Polina V (a) Isakov, Artem O (b)
institución:(a) World-Class Research Center for Personalized Medicine, Almazov National Medical Research Centre, Saint Petersburg, Russia. pvpopova5@gmail.com. (b) Institute of Endocrinology, Almazov National Medical Research Centre, Saint Petersburg, Russia. pvpopova5@gmail.com.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
The tetracycline resistome is shaped by selection for specific resistance mechanisms by each antibiotic generation.
The tetracycline resistome is shaped by selection for specific resistance mechanisms by each antibiotic generation.
Fuente:Nature Communications
Extracto:
These patterns match the history of clinical deployment of tetracycline
drugs and resistance discovery in pathogens.
Cita:Nat Commun 2025 Feb 7; 16 (1) : 1452.
Autor/es:Blake, Kevin S (a) Xue, Yao-Peng (b)
institución:(a) The Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO, USA. (b) Department of Pathology and Immunology, Division of Laboratory and Genomic Medicine, Washington University School of Medicine, St. Louis, MO, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Deep learning-based prediction of autoimmune diseases.
Deep learning-based prediction of autoimmune diseases.
Fuente:Scientific Reports
Extracto:
These results
demonstrate the high accuracy, stability, and good generalization ability of the
two models, which makes them promising tools in the field of autoimmune disease
prediction and provides support for the use of the TCR bank for the noninvasive
detection of autoimmune disease non-invasive detection is supported.
Cita:Sci Rep 2025 Feb 7; 15 (1) : 4576.
Autor/es:Yang, Donghong (a) Peng, Xin (b)
institución:(a) School of Information Engineering, Jingdezhen Ceramic University, Jingdezhen, 333403, China. (b) School of Information Engineering, Jingdezhen Ceramic University, Jingdezhen, 333403, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Models based on dietary nutrients predicting all-cause and cardiovascular mortality in people with diabetes.
Models based on dietary nutrients predicting all-cause and cardiovascular mortality in people with diabetes.
Fuente:Scientific Reports
Extracto:
The nomogram models based on dietary nutrients can
predict long-term mortality of people with DM, and the higher intake of dietary
fiber and magnesium was associated with reduced risks of both long-term all-cause
and cardiovascular mortality.
Claves:DM, LASSO, Mortality, NHANES, Nomogram, RF
Cita:Sci Rep 2025 Feb 7; 15 (1) : 4600.
Autor/es:Wang, Fang (a) Mao, Yukang (b)
institución:(a) Center for Cardiovascular Disease, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, 242# Guangji Road, Suzhou, 215000, Jiangsu, China. (b) Center for Cardiovascular Disease, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, 242# Guangji Road, Suzhou, 215000, Jiangsu, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Development and validation of a risk prediction model for PICC-related venous thrombosis in patients with cancer
Development and validation of a risk prediction model for PICC-related venous thrombosis in patients with cancer
Fuente:Scientific Reports
Tipo de trabajo:Estudio de cohortes
Extracto:
Further external validation studies of this nomogram model
on a large sample are required.
Claves:Cancer, Peripherally inserted central catheter, Risk prediction model, Thrombosis
Cita:Sci Rep 2025 Feb 7; 15 (1) : 4654.
Autor/es:Hu, Zeyin (a) Luo, Mengna (b)
institución:(a) Cather clinic, State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou, China. (b) Department of Nasopharyngeal Carcinoma, State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Incidence of type 2 diabetes and metabolic syndrome by Occupation - 10-Year follow-up of the Gutenberg Health Study.
Incidence of type 2 diabetes and metabolic syndrome by Occupation - 10-Year follow-up of the Gutenberg Health Study.
Fuente:Bmc Public Health
Extracto:
This study shows wide differences in the incidence of type 2
diabetes and metabolic syndrome between occupational groups and highlights the
vulnerability of certain occupations. As the workplace is an important platform
for interventions, the findings of this study could guide the development of more
nuanced and effective workplace health initiatives to promote a healthier
workforce for the future.
institución:(a) Division Work and Health, Federal Institute for Occupational Safety and Health (BAuA), Berlin, Germany. gutenberg@baua.bund.de. (b) Division Work and Health, Federal Institute for Occupational Safety and Health (BAuA), Berlin, Germany.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
