Olvidé mi contraseña
Asóciese a SIIC en Internet para utilizar sin límites tanto siicsalud como la totalidad de los servicios bibliográficos de la institución.
SIIC selecciona textos completos de calidad y de reciente publicación en fuentes prestigiosas del mundo
indizadas por SIIC Data Bases, capturadas en las mismas colecciones o en diversas bases especializadas.
La creciente cantidad de artículos con Acceso Abierto (Open
Access) amplía la oferta de lectura pero a su vez también, entre
tanta abundancia, complica al lector en su encuentro con los estudios
fundamentales. Para facilitarlo, profesionales biomédicos de SIIC
consultan diariamente una profusa cantidad de documentos que nutrirán
Textos completos autorizados (TCA).
Las citas de la sección TCA enlazan de manera legal, autorizada y
gratuita con los textos completos (full text) publicados en
los sitios oficiales de sus respectivas fuentes.
SIIC creó, produjo y opera con exclusividad el software TCA para la
interpretación de los diversos campos documentales que integran la
estructura de un estudio: especialidad, modalidad del estudio,
fuente, fechas de publicación y selección, definición de la fuente,
limitaciones de consulta, resumen en castellano, etc.
Si bien la mayoría de los textos seleccionados corresponden a
artículos originales, revisiones y guías, los lectores también
encontrarán comentarios, entrevistas, notas periodísticas, cartas a
autores u otros textos precursores de debates o aclaratorios.
Sociedad Iberoamericana de Información Científica (SIIC) selects
complete quality-full texts which have been recently published in
renowned sources worldwide and are indexed by SIIC Data
Bases.
The increasing number of Open Access articles widens the reading offer
but, also, such myriad complicates the readers search of fundamental
articles. To facilitate this, SIIC biomedical professionals daily
consult a profuse amount of documents that will feed
Authorized Full Texts (TCA, Spanish acronym).
The citations of the AFT section link legally, authorized and free of
charge with the full texts published in the official web sites of
their corresponding sources.
SIIC created, produced and handles the AFT software that deciphers
the various documentary fields that form part of the structure of a
study: specialty, study style, source, publication and selection
dates, source definition, query limitations, summary in Spanish,
etc.
While most of the selected texts belong to original articles,
reviews, and guidelines, readers will also find commentaries,
interviews, journalistic reports, letters to authors or other texts
that may lead to discussions or clarifications.
Adjuvant radiotherapy in postmenopausal women with early-stage ER-positive breast cancer
Adjuvant radiotherapy in postmenopausal women with early-stage ER-positive breast cancer
Fuente:Medicine
Tipo de trabajo:Revisión sistemática
Extracto:
Postoperative
radiotherapy significantly reduces local and regional recurrence following BCS in
early estrogen receptor-positive elderly BC with limited value on distant
recurrence or mortality. The risk-benefit ratio should be determined for every
patient to avoid overtreatment of a significant proportion of patients.
Cita:Medicine (Baltimore) 2025 Feb 21; 104 (8) : e41632.
Autor/es:Taha, Amira M (a) Kamel, Hanaa Abdelmoneim (b)
institución:(a) Faculty of Medicine, Fayoum University, Fayoum, Egypt. (b) Rheumatology Department, Al Haram Hospital, Giza, Egypt.
Conflicto:The authors have no funding and conflicts of interest to disclose.
Threshold effect of non-high-density lipoprotein to high-density lipoprotein cholesterol ratio and hypertension in U.S. adults: NHANES 2005-2016.
Threshold effect of non-high-density lipoprotein to high-density lipoprotein cholesterol ratio and hypertension in U.S. adults: NHANES 2005-2016.
Fuente:Medicine
Extracto:
Furthermore, a non-linear positive correlation exists between NHHR and
hypertension risk, suggesting its potential as a predictive biomarker for early
hypertension prevention.
Cita:Medicine (Baltimore) 2025 Feb 21; 104 (8) : e41585.
Autor/es:Sha, Yanming (a) Cai, Yuzhou (b)
institución:(a) Department of Endocrinology, The First Affiliated Hospital of Kunming Medical University, Yun nan, China. (b) Department of Gastrointestinal Surgery, The First Affiliated Hospital of Kunming Medical University, Yun nan, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Plasma proteins and coronary atherosclerosis: A Mendelian randomization study.
Plasma proteins and coronary atherosclerosis: A Mendelian randomization study.
Fuente:Medicine
Extracto:
These findings may provide a new theoretical basis for future
research in coronary AS drug development and therapeutic strategies.
Cita:Medicine (Baltimore) 2025 Feb 21; 104 (8) : e41549.
Autor/es:Pan, Henan (a) Wu, Zongkai (b)
institución:(a) Department of Graduate School, Hebei Medical University, Shijiazhuang, Hebei, China. (b) Neurology Department, Hebei General Hospital, Shijiazhuang, Hebei, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Extracto:
This updated meta-analysis highlights the
significance of modifiable risk factors for AMD, including smoking, hypertension,
cardiovascular diseases, and diabetes. Early identification of AMD accompanied by
strategic management of these modifiable risk factors may preserve patients'
visual acuity without advancing to advanced stages.
Cita:Medicine (Baltimore) 2025 Feb 21; 104 (8) : e41599.
Autor/es:Babaker, Raghad (a) Alzimami, Lama (b)
institución:(a) Department of Ophthalmology, King Saud University, Riyadh, Saudi Arabia. (b) Faculty of medicine, King Faisal University, Al Ahsa, Saudi Arabia.
Conflicto:The authors have no funding and conflicts of interest to disclose.
Robotic-Assisted Minimally Invasive Direct Coronary Artery Bypass Grafting with Concomitant Left Atrial Appendage Exclusion.
Robotic-Assisted Minimally Invasive Direct Coronary Artery Bypass Grafting with Concomitant Left Atrial Appendage Exclusion.
Fuente:Brazilian Journal of Cardiovascular Surgery
Extracto:
The concomitant robotic approach proved to be feasible,
efficacious, and safe, with no postoperative mortality or stroke events during
follow-up.
institución:(a) Department of Surgery, School of Medicine, University of Colorado, Aurora, Colorado, United States of America. (b) Division of Cardiothoracic Surge ry, Department of Surgery, Morsani College of Medicine, University of South Florida, Tampa, Florida, United States of America.
Machine Learning-Based Prediction of Substance Use in Adolescents in Three Independent Worldwide Cohorts: Algorithm Development and Validation Study.
Machine Learning-Based Prediction of Substance Use in Adolescents in Three Independent Worldwide Cohorts: Algorithm Development and Validation Study.
Fuente:Journal of Medical Internet Research
Extracto:
Based on multinational datasets from South
Korea, the United States, and Norway, this study shows the potential of ML
models, particularly the XGBoost model, in predicting adolescent substance use.
These findings provide a solid basis for future research exploring additional
influencing factors or developing targeted intervention strategies.
Claves:ML, Norway, South Korea, United States, XGBoost, adolescent, adolescents, alcohol, intervention, interventions, machine learning, prediction, random forest, risk behavior, smoking, substance, substance use, survey, web-based survey
Cita:J Med Internet Res 2025 Feb 24; 27 : e62805.
Autor/es:Kim, Soeun (a) Kim, Hyejun (b)
institución:(a) Center for Digital Health, Medical Science Research Institute, Kyung Hee University Medical Center, Seoul, Republic of Korea. (b) Department of Precision Medicine, Kyung Hee University College of Medicine, Seoul, Republic of Korea.
institución:(a) Department of Thoracic Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China. (b) Department of Thoracic Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Association between METS-IR index and obstructive sleep apnea: evidence from NHANES.
Association between METS-IR index and obstructive sleep apnea: evidence from NHANES.
Fuente:Scientific Reports
Extracto:
The METS-IR
index is positively associated with the prevalence of OSA and shows superior
diagnostic accuracy compared to HOMA-IR, TG/HDL-C, and TyG index.
Claves:Cross-sectional study, Insulin resistance, METS-IR, NHANES, OSA
Cita:Sci Rep 2025 Feb 24; 15 (1) : 6654.
Autor/es:Yin, Huangyi (a) Huang, Wei (b)
institución:(a) Geriatric Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China. (b) Critical Care Medicine, The First People's Hospital of Chenzhou, Chenzhou, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Individual bioenergetic capacity as a potential source of resilience to Alzheimer's disease.
Individual bioenergetic capacity as a potential source of resilience to Alzheimer's disease.
Fuente:Nature Communications
Extracto:
Furthermore,
monitoring the bioenergetic capacity via blood acylcarnitine measurements can be
achieved using existing clinical assays.
Cita:Nat Commun 2025 Feb 24; 16 (1) : 1910.
Autor/es:Arnold, Matthias (a) Buyukozkan, Mustafa (b)
institución:(a) Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC, USA. matthias.arnold@helmholtz-muenchen.de. (b) Institute of Computational Biology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany. matthias.arnold@helmholtz-muenchen.de.
Conflicto:Competing interests: A.J.S. is a member of the Scientific Advisory Board of Bayer Oncology and of the Dementia Advisory Board of Siemens Medical Solutions USA, Inc.; A.J.S received in-kind support from Avid Radiopharmaceuticals, a subsidiary of Eli Lilly (PET tracer precursor); A.J.S. received Editorial Office Support as Editor-in-Chief from Springer-Nature Publishing (Brain Imaging and Behavior). P.M.D. has received research grants...
(through Duke University) from Lilly, Avanir, Bausch, Alzheimer’s Drug Discovery Foundation; P.M.D. has received advisory fees from Verily, Otsuka, Genomind, Cogniciti, Clearview, VitaKey, Neuronix, Neuroglee, and Transposon Therapeutics; P.M.D. owns shares or options in UMethod, Evidation Health, Transposon, Marvel Biome, and Advera Health; P.M.D. serves on the board of Apollo and is a co-inventor (through Duke University) on patents relating to dementia biomarkers, metabolomics, and therapies. R.K.D holds equity in Metabolon Inc. M.A., R.K.D., and G.K. are co-inventors (through Duke University/Helmholtz Zentrum München) on patents on applications of metabolomics in diseases of the central nervous system; M.A., R.K.D., G.K., and J.K. hold equity in Chymia LLC and IP in PsyProtix/atai Life Sciences N.V. that are exploring the potential for therapeutic applications targeting mitochondrial metabolism in treatment-resistant depression. JK is a confounder of iollo, advisor to Everfur, and advisor/part-time employee at ExactRx. The remaining authors declare no competing interests.
Insights from a methylome-wide association study of antidepressant exposure.
Insights from a methylome-wide association study of antidepressant exposure.
Fuente:Nature Communications
Extracto:
In this large investigation
of antidepressant exposure and DNA methylation, we demonstrate robust
associations which warrant further investigation to inform on the design of more
effective and tolerated treatments for depression.
Cita:Nat Commun 2025 Feb 24; 16 (1) : 1908.
Autor/es:Davyson, E (a) Shen, X (b)
institución:(a) Division of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK. (b) Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
Conflicto:Competing interests: R.E.M. is an advisor to the Epigenetic Clock Development Foundation and Optima Partners. D.L.M. was employed by Optima Partners Ltd in a part-time capacity. H.J.G. has received travel grants and speaker honoraria from Fresenius Medical Care, Neuraxpharm, Servier, Indorsia and Janssen Cilag, as well as research funding from Fresenius Medical Care. H.J.G. had personal contracts approved by the...
university administration for speaker honoraria and one IIT with Fresenius Medical Care. T.K. received unrestricted educational grants from Servier, Janssen, Recordati, Aristo, Otsuka, neuraxpharm. B.W.J.H.P. has received research funding (not related to the current paper) from Boehringer Ingelheim and Jansen Research. All other authors report no biomedical financial interests or potential conflicts of interest.
The association of chronic pain, painkiller use, and potential mediators with liver fat content.
The association of chronic pain, painkiller use, and potential mediators with liver fat content.
Fuente:Scientific Reports
Extracto:
For chronic pain patients with
potential liver health issues, aspirin may be prioritized as an analgesic option
due to its potential protective benefits, whereas steroid medications should be
avoided.
institución:(a) General Practice Ward/International Medical Center Ward, General Practice Medical Center, West China Hospital, Sichuan University, Chengdu, China. (b) General Practice Ward/International Medical Center Ward, General Practice Medical Center, West China Hospital, Sichuan University, Chengdu, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Artificial Intelligence and Digital Twin in Healthcare, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan. kawazoe@m.u-tokyo.ac.jp. (b) Division of Drug Informatics, Keio University Faculty of Pharmacy, Tokyo, Japan.
Conflicto:Declarations. Competing interests: YK, KS, and ES belong to the Artificial Intelligence and Digital Twin in Healthcare, Graduate School of Medicine, University of Tokyo, which is an endowment department supported by an unrestricted grant from EM Systems, EPNextS, MRP Co., Ltd., SHIP HEALTHCARE HOLDINGS, Inc., SoftBank Corp., and NEC Corporation; these organizations had no control over the interpretation, writing, or...
publication of this work. All authors declare no financial or non-financial competing interests.
Atrial fibrillation risk model based on LASSO and SVM algorithms and immune infiltration of key mitochondrial energy metabolism genes.
Atrial fibrillation risk model based on LASSO and SVM algorithms and immune infiltration of key mitochondrial energy metabolism genes.
Fuente:Scientific Reports
Extracto:
The findings indicate that
MEMRGs interact with immune responses in AF, offering insights into the potential
molecular mechanisms and therapeutic targets for AF.
institución:(a) Department of Cardiology, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, 363000, Fujian, China. (b) Department of Cardiology, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, 363000, Fujian, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Genetic analyses reveal association between rosacea and cardiovascular diseases.
Genetic analyses reveal association between rosacea and cardiovascular diseases.
Fuente:Scientific Reports
Extracto:
We are the first to use MR
analysis to explore the casual relationship between rosacea and the risk of
various CVDs, revealing an increased risk of HTN in patients with rosacea.
Claves:Cardiovascular disease, Mendelian randomization, Rosacea, Single nucleotide polymorphisms
Cita:Sci Rep 2025 Feb 24; 15 (1) : 6657.
Autor/es:Gao, Yafang (a) Xu, Chengan (b)
institución:(a) Heart Center, Department of Cardiovascular Medicine, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China. (b) Department of Cardiology, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Autor/es:Niewinski, Piotr (a) Tubek, Stanislaw (b)
institución:(a) Institute of Heart Diseases, Wrocław Medical University, Ul. Borowska 213, 50-556, Wrocław, Poland. piotr.niewinski@umw.edu.pl. (b) Clinical Department of Cardiology, Jan Mikulicz Radecki University Hospital in Wrocław, Wrocław, Poland. piotr.niewinski@umw.edu.pl.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
The efficiency of endocardial suture occlusion of the left atrial appendage at a single institution: MICs vs. sternotomy.
The efficiency of endocardial suture occlusion of the left atrial appendage at a single institution: MICs vs. sternotomy.
Fuente:Bmc Cardiovascular Disorders
Tipo de trabajo:Estudio clínico
Extracto:
Compared to sternotomy, residual shunting after MICS was more
common. CT imaging analysis of 22 patients with failed closure in the MICS group
showed that residual shunting was mainly concentrated on margins of the suture
(anterior superior and posterior inferior) (86%), with a middle area accounting
for 3 (14%). Based on this finding, reinforcing the suture margins may
significantly reduce the incidence of incomplete closure. THE CLINICAL TRIAL
NUMBER: KY-2023-001.
Claves:Cardiac computed tomography, Endocardial suture occlusion, Left atrial appendage closure, Left atrial appendage patency, Minimally invasive cardiac surgery
Cita:BMC Cardiovasc Disord 2025 Feb 24; 25 (1) : 128.
Autor/es:Huang, Chengfeng (a) Huang, Jiawen (b)
institución:(a) Department of Cardiovascular Surgery, The First Affiliated Hospital, Jinan University, 613 Whampoa Avenue, Tianhe District, Guangzhou, 510630, China. (b) Department of Pharmacy, The First Affiliated Hospital, Jinan University, Guangzhou, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
A Chinese patient with cardiogenic stroke and warfarin resistance
A Chinese patient with cardiogenic stroke and warfarin resistance
Fuente:Bmc Neurology
Tipo de trabajo:Caso clínico
Extracto:
When considering warfarin resistance, it is important
to actively search for the cause of resistance early on. If the cause is
determined, appropriate measures should be taken. If the cause is not determined
or cannot be resolved, the dose can be gradually increased under close
monitoring, alternatives can be actively adopted, and patients can be informed
and educated.
Claves:Anticoagulant therapy, Atrial fibrillation, Case report, Cerebral infarction, Warfarin resistance
Cita:BMC Neurol 2025 Feb 24; 25 (1) : 77.
Autor/es:Du, Xiaoyan (a) Zhang, Peng (b)
institución:(a) Department of Neurology, Yongchuan Hospital of Chongqing Medical University, 439 Xuanhua Road, Yongchuan District, Chongqing, China. (b) Chongqing key laboratory of cerebrovascular disease research, 439 Xuanhua Road, Yongchuan District, Chongqing, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Comparative clinical frailty scale and hospital frailty risk score in identifying frailty and predicting mid-term outcomes in older patients with acute coronary syndrome
Comparative clinical frailty scale and hospital frailty risk score in identifying frailty and predicting mid-term outcomes in older patients with acute coronary syndrome
Fuente:Bmc Geriatrics
Tipo de trabajo:Estudio de cohortes
Extracto:
Although
a fair correlation existed between the CFS and the HFRS in older patients with
ACS, HFRS demonstrated limited predictive validity for mid-term mortality. We
advocate for a revised cutoff (HFRS ≥ 1.15 points) to enhance its sensitivity and
predictive accuracy. Future research should prioritize the integration of
additional clinical biomarkers and conducting longitudinal studies to assess the
efficacy of targeted interventions informed by frailty scores, ultimately
striving to improve outcomes in this vulnerable population.
institución:(a) Department of Geriatrics and Gerontology, University of Medicine and Pharmacy at Ho Chi Minh City, 217 Hong Bang, Ward 7, District 5, Ho Chi Minh City, Vietnam. nguyenvtan10@ump.edu.vn. (b) Department of Interventional Cardiology, Thong Nhat Hospital, Ho Chi Minh City, Vietnam. nguyenvtan10@ump.edu.vn.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Big data analysis of influenza vaccination and liver cancer risk in hypertensive patients
Big data analysis of influenza vaccination and liver cancer risk in hypertensive patients
Fuente:Bmc Gastroenterology
Tipo de trabajo:Estudio de cohortes
Extracto:
In summary,
influenza vaccination is linked to a decreased risk of liver cancer in
individuals with hypertension. However, unmeasurable confounders may have been
present in the analysis.
Claves:Hypertension, Influenza vaccination, Liver cancer
Cita:BMC Gastroenterol 2025 Feb 24; 25 (1) : 109.
Autor/es:Chiu, Chun-Chih (a) Hao, Wen-Rui (b)
institución:(a) Division of Cardiology, Department of Internal Medicine, Shuang Ho Hospital, Taipei Medical University, New Taipei City, 23561, Taiwan. (b) Taipei Heart Institute, Taipei Medical University, Taipei, Taiwan.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Mediating role of organized sports participation on the relationship between body fatness and arterial wall thickness among adolescents: ABCD Growth Study.
Mediating role of organized sports participation on the relationship between body fatness and arterial wall thickness among adolescents: ABCD Growth Study.
Fuente:Bmc Pediatrics
Extracto:
Sports participation mediates the relationship
between BF and arterial thickness in adolescent boys.
Autor/es:Torres, Wésley (a) Maillane-Vanegas, Santiago (b)
institución:(a) Laboratory of InVestigation in Exercise (LIVE), Department of Physical Education,, Sao Paulo State University (UNESP), Presidente Prudente, Sao Paulo, Brazil. wesleytorres_wt@yahoo.com.br. (b) Faculty of Sport and Health Sciences, University of Jyväskylä, Jyvaskyla, Finland. wesleytorres_wt@yahoo.com.br.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
