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The increasing number of Open Access articles widens the reading offer
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SIIC created, produced and handles the AFT software that deciphers
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institución:(a) Department of Public Health and Pediatric Sciences, University of Turin, 10126 Turin, Italy. (b) Pediatric Endocrinology Unit, Regina Margherita Children's Hospital, 10126 Turin, Italy.
Early Life Determinants of Overweight and Obesity in a Sample of Mexico City Preschoolers.
Early Life Determinants of Overweight and Obesity in a Sample of Mexico City Preschoolers.
Fuente:Nutrients
Extracto:
In this study, gestational age, sex, birth BMI, and the duration of
exclusive breastfeeding were the most important determinants of BMI and the
prevalence of overweight and obesity in children up to 5 years of age. Further
studies are needed to thoroughly explore the role of family income and other
factors.
Claves:Mexico, body mass index, breastfeeding, exclusive breastfeeding, nutritional status, pediatric obesity, preschooler
Cita:Nutrients 2025 Feb 15; 17 (4)
Autor/es:Sámano, Reyna (a) Lopezmalo-Casares, Salma (b)
institución:(a) Coordinación de Nutrición y Bioprogramación, Instituto Nacional de Perinatología, Secretaría de Salud Montes Urales 800, Lomas de Virreyes, Alcaldía Miguel Hidalgo, Ciudad de México 11000, Mexico. (b) Escuela de Dietética y Nutrición del ISSSTE, Callejón Vía, Av. San Fernando No. 12, San Pedro Apóstol, Tlalpan, Ciudad de México 14070, Mexico.
A Multivariate prediction model for amlodipine therapeutic efficacy in pediatric primary hypertension.
A Multivariate prediction model for amlodipine therapeutic efficacy in pediatric primary hypertension.
Fuente:Frontiers in Endocrinology
Extracto:
A
nomogram model with high predictive value for amlodipine therapeutic efficacy in
pediatric PH was established. This model may be potentially applied to guide the
selection of amlodipine for the treatment of pediatric PH.
institución:(a) Department of Cardiology, Children's Hospital, Capital Institute of Pediatrics, Beijing, China. (b) Department of Cardiology, Children's Hospital, Capital Institute of Pediatrics, Beijing, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Novel lipid profiles and atherosclerotic cardiovascular disease risk: insights from a latent profile analysis.
Novel lipid profiles and atherosclerotic cardiovascular disease risk: insights from a latent profile analysis.
Fuente:Lipids in Health and Disease
Extracto:
Four distinct lipid profiles were identified among
patients, with a particular profile characterized by lower levels of TC, LDL, and
TyG, as well as a lower HDL, emerging as the most predictive of adverse
cardiovascular outcomes. This underscores the critical need for a thorough lipid
profile analysis to pinpoint individuals at heightened risk for adverse
cardiovascular outcomes.
Claves:Atherosclerosis, Coronary artery disease, Latent class analysis, Lipids
Cita:Lipids Health Dis 2025 Feb 25; 24 (1) : 71.
Autor/es:Wan, Hongli (a) Wu, Haisheng (b)
institución:(a) Department of Central Laboratory, Xi'an No.1 Hospital, The First Affiliated Hospital of Northwest University, Xi'an City South Street powder Lane No. 30, Xi'an, Shaanxi, 710002, China. (b) Xi'an Key Laboratory for Innovation and Translation of Neuroimmunological Diseases, Xi'an No.1 Hospital, Xi'an City South Street powder Lane No. 30, Xi'an, Shaanxi, 710002, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Autor/es:Lupu, Maria (a) Pintilie, Iustina Mihaela (b)
institución:(a) Clinical Neurosciences Department, Paediatric Neurology, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania. (b) Department of Paediatric Neurology, Dr. Victor Gomoiu Children's Hospital, 022102 Bucharest, Romania.
A Genetic Test to Identify People at High Risk of Heart Failure.
A Genetic Test to Identify People at High Risk of Heart Failure.
Fuente:International Journal of Molecular Sciences
Extracto:
These
results highlight the critical role of genetic factors in the development of
heart failure and demonstrate this test's potential as a significant tool for
clinical HF risk prediction.
institución:(a) Centre for Diabetes Research, Harry Perkins Institute of Medical Research, Nedlands, WA 6009, Australia. (b) Stroke Research Centre, Perron Institute for Neurological and Translational Science, Nedlands, WA 6009, Australia.
Unravelling the Relationship Between Height, Lean Mass, Alzheimer's Disease and Cognition Through Mendelian Randomization.
Unravelling the Relationship Between Height, Lean Mass, Alzheimer's Disease and Cognition Through Mendelian Randomization.
Fuente:Genes
Tipo de trabajo:Metanálisis
Extracto:
Height may confound the genetic associations between lean mass and both cognitive
performance and AD risk. Residual direct effects of lean mass on AD risk cannot
be excluded due to limitations in statistical power and genetic instrument
strength in MVMR. These findings emphasize the necessity of adjusting for height
when using MR to investigate the clinical effects of lean mass.
Claves:Alzheimer’s disease, Mendelian randomization, cognition, height, lean mass
Cita:Genes (Basel) 2025 Jan 21; 16 (2)
Autor/es:Huang, Jingxian (a) Zhang, Linxuan (b)
institución:(a) Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London W12 0BZ, UK. (b) Sequoia Genetics, Translation & Innovation Hub, London W12 0BZ, UK.
Taxifolin as a Therapeutic Potential for Weight Loss: A Retrospective Longitudinal Study.
Taxifolin as a Therapeutic Potential for Weight Loss: A Retrospective Longitudinal Study.
Fuente:Nutrients
Extracto:
Long-term daily oral intake
of taxifolin may safely and sustainably prevent or manage obesity.
Claves:brown adipose tissue, high-density lipoprotein cholesterol, taxifolin, weight loss
Cita:Nutrients 2025 Feb 16; 17 (4)
Autor/es:Hattori, Yorito (a) Nakaoku, Yuriko (b)
institución:(a) Department of Neurology, National Cerebral and Cardiovascular Center, 6-1 Kishibe-shimmachi, Suita 564-8565, Osaka, Japan. (b) Department of Preemptive Medicine for Dementia, National Cerebral and Cardiovascular Center, 6-1 Kishibe-shimmachi, Suita 564-8565, Osaka, Japan.
institución:(a) Department VII, Internal Medicine II, Discipline of Cardiology, "Victor Babeş" University of Medicine and Pharmacy, Eftimie Murgu Sq. No. 2, 300041 Timisoara, Romania. (b) Cardiology Clinic, "Pius Brinzeu" Clinical Emergency County Hospital Timisoara, Bd. Iosif Bulbuca No. 10, 300723 Timisoara, Romania.
Extracto:
Pulmonary arterial
hypertension-specific vasodilators targeting the endothelin pathway, nitric oxide
pathway, and prostacyclin pathway have improved the clinical functions and
hemodynamics in some patients with SAPH.
institución:(a) Department of Environmental Medicine, Kurume University School of Medicine, Kurume 830-0011, Japan. (b) Division of Cardiovascular Medicine, Department of Medicine, Kurume University School of Medicine, Kurume 830-0011, Japan.
Nonlinear association between glycated hemoglobin levels and mortality in elderly patients with non-diabetic chronic kidney disease: a national health and nutrition examination survey analysis.
Nonlinear association between glycated hemoglobin levels and mortality in elderly patients with non-diabetic chronic kidney disease: a national health and nutrition examination survey analysis.
Fuente:Frontiers in Endocrinology
Tipo de trabajo:Estudio de cohortes
Extracto:
This cohort study suggests that both low and high HbA1c levels are
associated with an increased risk of all-cause mortality in elderly patients with
non-diabetic CKD.
institución:(a) Department of Clinical Laboratory, The Second Affiliated Hospital of Gannan Medical University, Ganzhou, China. (b) Department of Clinical Laboratory, The Second Affiliated Hospital of Gannan Medical University, Ganzhou, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
institución:(a) Department of Neurology, First Affiliated Hospital of Naval Medical University, Shanghai, China. (b) KLATASDS-MOE, Academy of Statistics and Interdisciplinary Sciences, School of Statistics, East China Normal University, Shanghai, China.
Amiodarone use and prolonged mechanical ventilation after cardiac surgery: a single-center analysis.
Amiodarone use and prolonged mechanical ventilation after cardiac surgery: a single-center analysis.
Fuente:Bmc Cardiovascular Disorders
Extracto:
Postoperative use of amiodarone is a significant predictor of delayed extubation,
warranting careful consideration in clinical practice. Further research is needed
to clarify the causal relationship between amiodarone use and extubation
outcomes.
Cita:BMC Cardiovasc Disord 2025 Feb 24; 25 (1) : 129.
Autor/es:Li, Xin (a) Zhang, Haitao (b)
institución:(a) Department of Cardiac Surgery, Nanjing Drum Tower Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Graduate School of Peking Union Medical College, Beijing, China. (b) Department of Cardiac Surgery, Nanjing Drum Tower Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Graduate School of Peking Union Medical College, Beijing, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Relationship of tobacco smoking to cause-specific mortality: contemporary estimates from Australia.
Relationship of tobacco smoking to cause-specific mortality: contemporary estimates from Australia.
Fuente:Bmc Medicine
Extracto:
Smoking continues to cause a
substantial proportion of deaths in low-prevalence settings, including Australia,
highlighting the importance of accelerated tobacco control.
Claves:Cause of death, Fatal burden of disease, Smoking, Tobacco
Cita:BMC Med 2025 Feb 25; 23 (1) : 115.
Autor/es:Joshy, Grace (a) Soga, Kay (b)
institución:(a) National Centre for Epidemiology and Population Health (NCEPH), The Australian National University, Acton, Canberra, ACT, 2601, Australia. Grace.Joshy@anu.edu.au. (b) National Centre for Epidemiology and Population Health (NCEPH), The Australian National University, Acton, Canberra, ACT, 2601, Australia.
Conflicto:Declarations. Ethics approval and consent to participate: Individuals gave written informed consent to take part in the study, including consent for follow-up through repeated data collection and linkage of their data to population health databases. Ethical approval for the conduct of the 45 and Up Study was provided by the University of New South Wales Human Research Ethics Committee. Ethical...
approval for this research project was provided by the NSW Population and Health Services Research Ethics Committee (12/CIPHS/31) and the Australian National University Human Research Ethics Committee (2012/504, 2019/022). The National Cause of Death Unit Record Files used in this study are de-identified data provided by the Queensland Registry of Births, Deaths and Marriages, which is the Australian Coordinating Registry for unit-record level data. The cause of death data provided by AIHW does not contain identifiers such as name, address or other data fields that in isolation can identify an individual. Informed consent is not applicable for these data. Consent for publication: N/A. Competing interests: KC is co-principal investigator of an unrelated investigator-initiated trial of cervical screening in Australia (Compass; ACTRN12613001207707 and NCT02328872), which is conducted and funded by the VCS Foundation. The VCS Foundation received equipment and a funding contribution from Roche Molecular Systems USA. However, neither KC nor her institution on her behalf (Cancer Council NSW) receives direct funding from industry for this trial or any other project. KC is also co-PI on a major implementation program Elimination of Cervical Cancer in the Western Pacific which has received support from the Minderoo Foundation and equipment donations from Cepheid Inc. EB reports grants from NHMRC, during the conduct of the study.
Additive impact of metabolic syndrome and sarcopenia on all-cause and cause-specific mortality: an analysis of NHANES.
Additive impact of metabolic syndrome and sarcopenia on all-cause and cause-specific mortality: an analysis of NHANES.
Fuente:Frontiers in Endocrinology
Extracto:
The coexistence of MetS and SP
significantly increases the risk of all-cause and cause-specific mortality.
Individuals with either condition may require more vigilant management to prevent
the onset of the other condition, thereby reducing mortality rates. These
findings highlight the importance of integrated healthcare strategies targeting
both MetS and SP to improve patient outcomes and longevity.
institución:(a) Department of Rheumatology and Immunology, West China Hospital of Sichuan University, Chengdu, Sichuan, China. (b) General Practice Ward/International Medical Center Ward, General Practice Medical Center, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Conflicto:The authors declare that financial support was received for the research, authorship, and/or publication of this article.
Effect of water-based aerobic training on anthropometric, biochemical, cardiovascular, and explosive strength parameters in young overweight and obese women: a randomized controlled trial.
Effect of water-based aerobic training on anthropometric, biochemical, cardiovascular, and explosive strength parameters in young overweight and obese women: a randomized controlled trial.
Fuente:Peerj
Tipo de trabajo:Estudio aleatorizado y controlado
Extracto:
Our findings indicate that water-based aerobic
training could be a useful program to enhance anthropometric, biochemical,
cardiovascular, and explosive strength parameters in young overweight and obese
women compared to inactive persons.
institución:(a) Research Unit: Sport Sciences, Health and Movement, University of Jendouba, El Kef, Tunisia. (b) High Institute of Sport and Physical Education of Kef, University of Jendouba, El Kef, Tunisia.
Conflicto:Prof. Yung-Sheng Chen is an Academic Editor for PeerJ.
Malnutrition and sarcopenia in inpatient rehabilitation: prevalence and associations with changes in bodyweight, muscle strength, and functional independence.
Malnutrition and sarcopenia in inpatient rehabilitation: prevalence and associations with changes in bodyweight, muscle strength, and functional independence.
Fuente:Journal of Rehabilitation Medicine
Extracto:
Malnutrition and sarcopenia are highly prevalent during inpatient
rehabilitation. Nevertheless, dietitians are often not involved in the therapy.
While nutritional parameters and functional independence improve, patients with
malnutrition and sarcopenia remain on a lower level after 3 weeks of
rehabilitation. Long-term follow-up after rehabilitation is recommended to
prevent nutritional and muscular decline and related negative health outcomes.
Cita:J Rehabil Med 2025 Feb 25; 57 : jrm42215.
Autor/es:Lehmann, Undine (a) Uhlmann, Katja (b)
institución:(a) Division Nutrition and Dietetics, Department of Health Professions, Bern University of Applied Sciences, Bern, Switzerland. undine.lehmann@bfh.ch. (b) Division Nutrition and Dietetics, Department of Health Professions, Bern University of Applied Sciences, Bern, Switzerland.
institución:(a) Department of Geriatrics, The People's Hospital of Changshou, Chongqing, China. (b) Department of Geriatrics, The People's Hospital of Changshou, Chongqing, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Epimaps of the SARS-CoV-2 Receptor-Binding Domain Mutational Landscape: Insights into Protein Stability, Epitope Prediction, and Antibody Binding.
Epimaps of the SARS-CoV-2 Receptor-Binding Domain Mutational Landscape: Insights into Protein Stability, Epitope Prediction, and Antibody Binding.
Fuente:Biomolecules
Extracto:
Future antibody development could focus on broadly neutralising antibodies,
engineering antibodies with enhanced binding affinity, and targeting spike
protein regions beyond the RBD.
A Systematic Review of Vitamin D Supplementation in Oncology: Chance of Science or Effectiveness?
A Systematic Review of Vitamin D Supplementation in Oncology: Chance of Science or Effectiveness?
Fuente:Nutrients
Tipo de trabajo:Revisión
Extracto:
In this scoping review, VD is highlighted as a crucial
factor in preventing the side effects of neoadjuvant RT or CT, as well as
treating other treatment-related health conditions, such as osteoporosis, as well
as ameliorating the side effects (nausea, vomiting, fatigue) associated with
aggressive CT and RT.
Claves:adverse effects, cancer, neoadjuvant therapy, neoplasm, vitamin D
Cita:Nutrients 2025 Feb 11; 17 (4)
Autor/es:Afonso, Marta Lourenço (a) Capelas, Manuel Luís (b)
institución:(a) Universidade Católica Portuguesa, Faculty of Health Sciences and Nursing, 1649-023 Lisbon, Portugal. (b) Universidade Católica Portuguesa, Faculty of Health Sciences and Nursing, Centre for Interdisciplinary Research in Health (CIIS), 1649-023 Lisbon, Portugal.