Determining the influence of a sleep improvement intervention on medical students' sleep and fatigue: protocol of the PROMESS-Sleep clinical trial.

Determining the influence of a sleep improvement intervention on medical students' sleep and fatigue: protocol of the PROMESS-Sleep clinical trial.

Fuente:Bmc Medical Education

Tipo de trabajo:Estudio clínico

Extracto: TRIAL REGISTRATION: ClinicalTrials.gov: NCT06297330; retrospectively registered.

Claves:Actigraphy, Curriculum, Disturbance, Fatigue, Health intervention, PSQI, Pedagogy, Peer coaching, Physiology, Prevention, Remediation, Sleep

Cita:BMC Med Educ 2025 Feb 19; 25 (1) : 267.

Autor/es:Ruet, Axelle (a)
Ndiki Mayi, Evrard-Florentin (b)

institución:(a) Faculté de Médecine Lyon Est, Université Claude Bernard Lyon 1, Lyon, France.
(b) Faculté de Médecine Lyon Sud, Université Claude Bernard Lyon 1, Lyon, France.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12909-024-06422-x

Identification of benzo(a)pyrene-related toxicological targets and their role in chronic obstructive pulmonary disease pathogenesis: a comprehensive bioinformatics and machine learning approach.

Identification of benzo(a)pyrene-related toxicological targets and their role in chronic obstructive pulmonary disease pathogenesis: a comprehensive bioinformatics and machine learning approach.

Fuente:Bmc Pharmacology & Toxicology

Extracto: The study elucidates the molecular mechanisms of BaP-induced COPD, specifically highlighting the role of oxidative stress and inflammation pathways in promoting immune cell infiltration. The identified feature genes may serve as potential biomarkers and therapeutic targets. Additionally, the constructed nomogram demonstrates high accuracy in predicting COPD risk, providing a valuable tool for clinical application in BaP-exposed individuals.

Claves:Benzo(a)pyrene, Bioinformatics, Chronic obstructive pulmonary disease, Immune score, KEGG, Polycyclic aromatic hydrocarbons

Cita:BMC Pharmacol Toxicol 2025 Feb 17; 26 (1) : 33.

Autor/es:Deng, Jiehua (a)
Wei, Lixia (b)

institución:(a) Department of Respiratory and Critical Medicine, The Eighth Affiliated Hospital, Sun Yat-sen University, 3025 Shennan Zhong Lu, Shenzhen City, Guangdong Province, 518033, China.
(b) Department of Respiratory and Critical Medicine, The Eighth Affiliated Hospital, Sun Yat-sen University, 3025 Shennan Zhong Lu, Shenzhen City, Guangdong Province, 518033, China. weilx004011@aliyun.com.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s40360-025-00842-1

Cross-Cultural Adaptation of the Clinical Frailty Scale for Critically Ill Patients in Spain and Concurrent Validity With FRAIL-Es.

Cross-Cultural Adaptation of the Clinical Frailty Scale for Critically Ill Patients in Spain and Concurrent Validity With FRAIL-Es.

Fuente:Nursing Open

Extracto: PATIENT OR PUBLIC CONTRIBUTION: Assessing frailty upon admission can be helpful in the care of frail patients, allowing the development of specific care plans based on pre-existing frailty.

Claves:cross‐cultural comparison, frailty, intensive care units, validation studies

Cita:Nurs Open 2025 Feb; 12 (2) : e70064.

Autor/es:Arias-Rivera, Susana (a)
Moro-Tejedor, María Nieves (b)

institución:(a) Doctoral program in Nursing and Health, University of Barcelona, Barcelona, Spain.
(b) Department of Nursing Research, Hospital Universitario de Getafe, Getafe(Madrid), Spain.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1002/nop2.70064

Cardiac Characteristics of Hospitalized Influenza Patients: An Interim Analysis From the FluHeart Study.

Cardiac Characteristics of Hospitalized Influenza Patients: An Interim Analysis From the FluHeart Study.

Fuente:Influenza and Other Respiratory Viruses

Tipo de trabajo:Estudio de cohortes

Extracto: In this interim analysis of the FluHeart study, both RV and LV function measures were significantly impaired in hospitalized influenza patients compared with matched general population controls. The extent of impairment resembled that observed in hospitalized COVID-19 patients.

Claves:COVID‐19, cardiac function, influenza infection

Cita:Influenza Other Respir Viruses 2025 Feb; 19 (2) : e70067.

Autor/es:Skaarup, Kristoffer Grundtvig (a)
Davidovski, Filip Soeskov (b)

institución:(a) Department of Cardiology, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark.
(b) Center for Translational Cardiology and Pragmatic Randomized Trials, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1111/irv.70067

Relationship between difference in endotracheal tube cuff area and airway area with minimum cuff pressure for adequate airway sealing: a prospective observational study.

Relationship between difference in endotracheal tube cuff area and airway area with minimum cuff pressure for adequate airway sealing: a prospective observational study.

Fuente:Scientific Reports

Extracto: Patients with a lower cuff-airway area difference require a higher minimum cuff pressure to seal the airway.

Claves:Air leakage, Cuff pressure, Endotracheal intubation, Mechanical ventilation

Cita:Sci Rep 2025 Feb 18; 15 (1) : 5875.

Autor/es:Wu, Hong-Lei (a)
Wu, Yue-Hong (b)

institución:(a) Nursing Department, Affiliated Hospital of Nantong University, Jiangsu, 226001, China.
(b) College of Nursing, Anhui University of Chinese Medicine, Hefei, 230012, Anhui, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-025-85355-x

Association of insulin resistance surrogates with disease severity and adverse outcomes in chronic thromboembolic pulmonary hypertension

Association of insulin resistance surrogates with disease severity and adverse outcomes in chronic thromboembolic pulmonary hypertension

Fuente:Cardiovascular Diabetology

Tipo de trabajo:Estudio de cohortes

Extracto: METS-IR is an independent predictor of clinical worsening in patients with CTEPH. It offers a convenient marker for assessing disease severity and long-term outcomes in clinical risk assessment.

Claves:Chronic thromboembolic pulmonary hypertension, Insulin resistance, Metabolic score for insulin resistance, Prognosis, Severity

Cita:Cardiovasc Diabetol 2025 Feb 19; 24 (1) : 82.

Autor/es:Gao, Luyang (a)
Zhang, Sicheng (b)

institución:(a) Center for Respiratory and Pulmonary Vascular Diseases, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 167, Beilishi Road, Xicheng District, Beijing, 100037, China.
(b) Center for Respiratory and Pulmonary Vascular Diseases, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 167, Beilishi Road, Xicheng District, Beijing, 100037, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12933-025-02630-x

[Research Progress of Pulmonary Extranodal Marginal Zone Lymphoma].

Fuente:Zhongguo Fei Ai Za Zhi = Chinese Journal of Lung Cancer

Extracto: This paper reviews the epidemiology, pathogenesis, clinical manifestations, computed tomography (CT) features, pathological diagnosis, treatment and prognosis of pulmonary MALT lymphoma, providing reference for clinicians to further understanding of the disease.
.

Claves:Anti-bacterial agents, Mucosa-associated lymphoid tissue lymphoma, NF-κB signal pathway, Primary pulmonary lymphoma, Rituximab

Cita:Zhongguo Fei Ai Za Zhi 2024 Dec 20; 27 (12) : 947-955.

Autor/es:Anti-bacterial agents, Mucosa-associated lymphoid tissue lymphoma, NF-κB signal pathway, Primary pulmonary lymphoma, Rituximab

institución:Anti-bacterial agents, Mucosa-associated lymphoid tissue lymphoma, NF-κB signal pathway, Primary pulmonary lymphoma, Rituximab

Formato:Informe impreso

Idioma:chi

País de fuente:China

Sitio web:http://dx.doi.org/10.3779/j.issn.1009-3419.2024.106.31

Completeness, timing, and guidance of percutaneous coronary intervention for myocardial infarction and multivessel disease

Fuente:Eurointervention Journal of Europcr in Collaboration With The Working Group On Interventional Cardiology of The European Society of Cardiology

Tipo de trabajo:Revisión sistemática

Extracto: In haemodynamically stable patients with acute MI and non-complex MV-CAD undergoing PCI, immediate CR following successful culprit lesion treatment reduces recurrent MI compared with IRA-only revascularisation and staged CR. Whether CR is associated with reduced cardiovascular death remains uncertain.

Cita:EuroIntervention 2025 Feb 17; 21 (4) : e203-e216.

Autor/es:Laudani, Claudio (a)
Occhipinti, Giovanni (b)

institución:(a) Division of Cardiology, Azienda Ospedaliero-Universitaria Policlinico "Rodolico - San Marco", University of Catania, Catania, Italy.
(b) Division of Cardiology, Azienda Ospedaliero-Universitaria Policlinico "Rodolico - San Marco", University of Catania, Catania, Italy.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Francia

Sitio web:http://dx.doi.org/10.4244/EIJ-D-24-00814

Effects of proton pump inhibitors on gastrointestinal bleeding and cardiovascular outcomes in myocardial infarction patients treated with DAPT.

Fuente:Eurointervention Journal of Europcr in Collaboration With The Working Group On Interventional Cardiology of The European Society of Cardiology

Tipo de trabajo:Guía

Extracto: In real-world data from a large study of East Asian patients with AMI undergoing PCI and maintaining DAPT, PPI use significantly reduced the risk of major gastrointestinal bleeding without increasing ischaemic events, irrespective of bleeding risk or type of P2Y(12) inhibitor. (ClinicalTrials.gov: NCT06241833).

Cita:EuroIntervention 2025 Feb 17; 21 (4) : e229-e239.

Autor/es:Kang, Danbee (a)
Choi, Ki Hong (b)

institución:(a) Center for Clinical Epidemiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
(b) Department of Clinical Research Design and Evaluation, SAIHST, Sungkyunkwan University, Seoul, Republic of Korea.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Francia

Sitio web:http://dx.doi.org/10.4244/EIJ-D-24-00673

Functional or anatomical assessment of non-culprit lesions in acute myocardial infarction.

Fuente:Eurointervention Journal of Europcr in Collaboration With The Working Group On Interventional Cardiology of The European Society of Cardiology

Extracto: When assessing NCLs during the index procedure in AMI patients, OCT-defined TCFA serves as the dominant prognostic predictor for long-term clinical outcomes, rather than μQFR-determined physiological significance.

Cita:EuroIntervention 2025 Feb 17; 21 (4) : e217-e228.

Autor/es:Xu, Xueming (a)
Fang, Chao (b)

institución:(a) State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Harbin, China.
(b) Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Francia

Sitio web:http://dx.doi.org/10.4244/EIJ-D-24-00720

Do not ignore persistent pain after total knee arthroplasty: Pseudoaneurysm of the popliteal artery after primary total knee arthroplasty.

Fuente:Ulusal Travma Ve Acil Cerrahi Dergisi = Turkish Journal of Trauma & Emergency Surgery Tjtes

Extracto: In cases of severe pain that is inconsistent with the clinical and postoperative period, popliteal pseudoaneurysms should be considered.

Cita:Ulus Travma Acil Cerrahi Derg 2025 Feb; 31 (2) : 202-206.

Autor/es:Dincal, Turgut (a)
Gencer, Batuhan (b)

institución:(a) Department of Orthopaedics and Traumatology, Marmara University Pendik Training and Research Hospital, İstanbul,Türkiye.
(b) Department of Orthopaedics and Traumatology, Marmara University Pendik Training and Research Hospital, İstanbul,Türkiye.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Turquía

Sitio web:http://dx.doi.org/10.14744/tjtes.2025.70124

Mapping the therapeutic landscape in emergency incisional hernia

Fuente:Hernia The Journal of Hernias and Abdominal Wall Surgery

Tipo de trabajo:Revisión

Extracto: This review highlights a paucity of randomized studies guiding emergency incisional hernia management. Key issues identified include inconsistent definitions of emergency presentation, limited data on hernia characteristics, and a lack of standardized outcome reporting. Future research should focus on developing a unified classification system for emergency incisional hernias, evaluating the role of imaging in decision-making, and conducting comparative studies on various treatment strategies across different clinical scenarios.

Claves:Emergency repair, Hernia repair, Incisional hernia, Postoperative complications, Scoping review, Surgical mesh

Cita:Hernia 2025 Feb 18; 29 (1) : 102.

Autor/es:Quiroga-Centeno, Andrea Carolina (a)
Schaaf, Sebastian (b)

institución:(a) Department of Surgery, Universidad Industrial de Santander, Bucaramanga, Colombia. caroline_aqc@hotmail.com.
(b) School of Translational Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. caroline_aqc@hotmail.com.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Francia

Sitio web:http://dx.doi.org/10.1007/s10029-025-03278-y

Timing of discharge of pediatric patients post cardiac catheterization.

Timing of discharge of pediatric patients post cardiac catheterization.

Fuente:Annals of Saudi Medicine

Tipo de trabajo:Revisión

Extracto: Same-day discharge following catheterization is feasible for the majority of pediatric patients and can contribute to reduced healthcare costs and improved patient satisfaction. We developed a fast-track protocol for assessing the timing of discharge after pediatric cardiac catheterization, outlining potential indications and contraindications for same-day discharge. Factors associated with prolonged hospital stays include interventions in the neonatal period and procedure-related complications. Careful patient selection and monitoring impleare essential to ensure optimal outcomes. LIMITATIONS: The retrospective nature of the study and the single-center experience may limit the generalizability of the findings.

Cita:Ann Saudi Med 2025 Jan-Feb; 45 (1) : 40-49.

Autor/es:Alakhfash, Ali A (a)
Al Mesned, Abdulrahman A (b)

institución:(a) From the From the Department of Pediatric Cardiology, Prince Sultan Cardiac Center in Qassim, Buraidah, Qassim, Saudi Arabia.
(b) From the From the Department of Pediatric Cardiology, Prince Sultan Cardiac Center in Qassim, Buraidah, Qassim, Saudi Arabia.

Conflicto:CONFLICT OF INTEREST: None.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Arabia Saudí

Sitio web:http://dx.doi.org/10.5144/0256-4947.2025.40

Mechanisms of urate transport and uricosuric drugs inhibition in human URAT1.

Mechanisms of urate transport and uricosuric drugs inhibition in human URAT1.

Fuente:Nature Communications

Extracto: Benzbromarone and verinurad exert their inhibitory effect by blocking not only the binding of urate but also the structural isomerization of hURAT1.

Cita:Nat Commun 2025 Feb 10; 16 (1) : 1512.

Autor/es:Guo, Wenjun (a)
Wei, Miao (b)

institución:(a) State Key Laboratory of Membrane Biology, College of Future Technology, Institute of Molecular Medicine, Peking. University, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Beijing, 100871, China.
(b) Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, 100871, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41467-025-56843-5

Prediction of COVID-19 cases by multifactor driven long short-term memory (LSTM) model.

Prediction of COVID-19 cases by multifactor driven long short-term memory (LSTM) model.

Fuente:Scientific Reports

Extracto: Overall, the results of this study may provide insight for predictions of number of COVID-19 new cases in more countries/regions and offer some insightful recommendation for governments to carry out more effective policies to prevent COVID-19.

Claves:COVID-19, Disease prediction, LSTM, Machine learning, Pandemic prevention policy

Cita:Sci Rep 2025 Feb 10; 15 (1) : 4935.

Autor/es:Shao, Yanwen (a)
Wan, Tsz Kin (b)

institución:(a) Department of Biomedical Sciences, City University of Hong Kong, Hong Kong, China.
(b) Department of Electrical Engineering, City University of Hong Kong, Hong Kong, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-025-86698-1

Bioinformatics Analysis of coagulation-related genes in lung adenocarcinoma: unveiling prognostic indicators and treatment pathways.

Fuente:Scientific Reports

Extracto: Specifically, subgroups manifesting elevated PIK3CA expression might serve as foundational indicators for optimal treatment selection.

Claves:Coagulation, Immunotherapy, LUAD, PIK3CA, TME

Cita:Sci Rep 2025 Feb 10; 15 (1) : 4972.

Autor/es:Huang, Minliang (a)
Huang, Zhanghao (b)

institución:(a) Department of Thoracic Surgery, Medical School, Affiliated Hospital of Nantong University, Nantong University, Nantong, 226001, China.
(b) Nantong Key Laboratory of Translational Medicine in Cardiothoracic Diseases, and Research Institution of Translational Medicine in Cardiothoracic Diseases, Affiliated Hospital of Nantong University, NO.20, Xisi Road, Nantong, 226001, Jiangsu, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-025-87669-2

Contrast-enhanced magnetic resonance imaging based calf muscle perfusion and machine learning in peripheral artery disease.

Fuente:Scientific Reports

Extracto: Machine learning and CE-MRI derived measures of the calf microcirculation could be of interest in the study of PAD and disease severity.

Claves:Calf muscle perfusion, Machine learning, Microvascular circulation, Perfusion mapping, Peripheral artery disease, contrast-enhanced magnetic resonance imaging

Cita:Sci Rep 2025 Feb 10; 15 (1) : 4996.

Autor/es:Khagi, Bijen (a)
Belousova, Tatiana (b)

institución:(a) Penn State Heart and Vascular Institute, College of Medicine, Pennsylvania State University, 500 University Drive H047, Hershey, PA, 17033, USA.
(b) Methodist DeBakey Heart and Vascular Center, Houston Methodist Hospital, Houston, USA.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-025-87747-5

Drug coated balloon angioplasty for de novo coronary lesions in large vessels

Fuente:Scientific Reports

Tipo de trabajo:Revisión sistemática

Extracto: The incidence of target lesion revascularization appears to be similar to that of contemporary DES.

Claves:Acute coronary syndrome, Drug-coated balloon, Drug-eluting stent, Target lesion revascularization

Cita:Sci Rep 2025 Feb 10; 15 (1) : 4921.

Autor/es:Gobbi, Cecilia (a)
Giangiacomi, Francesco (b)

institución:(a) Department of Cardio-Thoracic-Vascular Diseases, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122, Milan, Italy. gobbi.cecilia.cg@gmail.com.
(b) Department of Cardio-Thoracic-Vascular Diseases, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122, Milan, Italy.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-025-85734-4

m7G gene expression and disease risk model construction in patients with herpes zoster.

Fuente:Scientific Reports

Tipo de trabajo:Revisión

Extracto: The results suggest that a nomogram based on NSUN2, AGO2, and SNUPN can predict the risk of herpes zoster, and the relationship between these genes and immune infiltration may influence the prognosis of herpes zoster.Trial registration: This study was approved by the Institutional Review Board of the Fujian Medical University Union Hospital (No 2023QH003).

Claves:Herpes zoster, Immune cells, N7-methylguanosine, Nomogram, Varicella-zoster virus

Cita:Sci Rep 2025 Feb 10; 15 (1) : 4881.

Autor/es:Lu, Lingling (a)
Cai, Fangze (b)

institución:(a) Department of Infectious Disease, Fujian Medical University Union Hospital, No. 29 Xinquan Road, Gulou District, Fuzhou, 350001, Fujian, China.
(b) Department of Infectious Disease, Fujian Medical University Union Hospital, No. 29 Xinquan Road, Gulou District, Fuzhou, 350001, Fujian, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-025-88664-3

Associations of heatwaves and their characteristics with ischaemic stroke hospital admissions.

Fuente:Scientific Reports

Extracto: This evidence has significant implications for the strategic planning of public health interventions to mitigate adverse health outcomes associated with heatwaves.

Cita:Sci Rep 2025 Feb 10; 15 (1) : 4929.

Autor/es:Yin, Jinyu (a)
Wang, Shiwen (b)

institución:(a) Department of Epidemiology and Medical Statistics, Xiangya School of Public Health, Central South University, Tongzipo Road 172, Yuelu District, Changsha, 410006, Hunan, China.
(b) Department of Epidemiology and Medical Statistics, Xiangya School of Public Health, Central South University, Tongzipo Road 172, Yuelu District, Changsha, 410006, Hunan, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-025-88557-5