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institución:(a) Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA, 19107, USA. (b) Department of Gastroenterology & Hepatology, Thomas Jefferson University Hospital, 132 S 10th St, Suite 480, Philadelphia, PA, 19107, USA.
Conflicto:Declarations. Conflict of interest: Dina Halegoua-DeMarzio: Consultant- Pfizer. Research Grant Support- Intercept, Galectin, BMS, Novo Nordisk, Viking, Pfizer; however, this article is solely the author’s work without any connection with Pfizer, Intercept, Galectin, BMS, Novo Nordisk, and Viking. All other authors have no conflict of interests. Ethical approval: Only aggregated counts and statistical summaries of de-identified information without any protected...
ed health information are received from participating HCOs, and no study-specific activities are performed in these retrospective analyses; therefore, TriNetX federated network has been granted a waiver from the Western institutional review board, including the Thomas Jefferson institutional review board.
Rapid rule-out of acute myocardial infarction using the 0/1-hour algorithm for cardiac troponins in emergency primary care: the OUT-ACS implementation study.
Rapid rule-out of acute myocardial infarction using the 0/1-hour algorithm for cardiac troponins in emergency primary care: the OUT-ACS implementation study.
Fuente:Bmc Primary Care
Extracto:
The ESC 0/1-hour algorithm effectively
assesses low-risk acute chest pain in emergency primary care, reinforcing its
gatekeeper role by managing these patients at a lower level of care.
Claves:Acute myocardial infarction, Biomarkers, Chest pain, Diagnostics, Primary care, Troponin
Cita:BMC Prim Care 2025 Feb 10; 26 (1) : 34.
Autor/es:Johannessen, Tonje R (a) Ruud, Sven Eirik (b)
institución:(a) Department of General Practice, University of Oslo, Oslo, Norway. t.r.johannessen@medisin.uio.no. (b) Oslo Accident and Emergency Outpatient Clinic, City of Oslo Health Agency, Oslo, Norway. t.r.johannessen@medisin.uio.no.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
The prevalence of frailty according to kidney function and its association with cognitive impairment, nutritional status, and clinical outcome.
The prevalence of frailty according to kidney function and its association with cognitive impairment, nutritional status, and clinical outcome.
Fuente:Bmc Nephrology
Extracto:
The prevalence of frailty increased
significantly as the CKD stage progressed. Particularly, CKD G5D group correlated
with frailty and nutritional status, leading to poor clinical outcomes.
Claves:CKD, Clinical outcomes, Cognitive impairment, Frailty, Nutritional status
Cita:BMC Nephrol 2025 Feb 10; 26 (1) : 65.
Autor/es:Yang, Tae-Won (a) Kang, YooMee (b)
institución:(a) Department of Neurology, Gyeongsang National University College of Medicine and Gyeongsang National University Changwon Hospital, Changwon, Republic of Korea. (b) Department of Internal Medicine, Gyeongsang National University College of Medicine and Gyeongsang National University Changwon Hospital, 11, Samjeongja-ro, Seongsan-gu, Changwon-si, Gyeongsangnam-do, Republic of Korea.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Knowledge, attitude, and practice of coronary heart disease patients towards antithrombotic therapy.
Knowledge, attitude, and practice of coronary heart disease patients towards antithrombotic therapy.
Fuente:Bmc Public Health
Extracto:
The surveyed patients with
CHD exhibited good attitudes, practices, and self-efficacy but demonstrated only
median knowledge levels toward antithrombotic therapy, especially about the
importance and precautions associated with antithrombotic treatment. Therefore,
initiatives aimed at improving adherence to antithrombotic therapy among CHD
patients should focus on the knowledge gaps, especially for patients in rural
areas. Improving the patient KAP could help improve the physician-patient
interaction.
Claves:Antithrombotic therapy, Attitude, Coronary heart disease, Knowledge, Medication adherence, Practice
Cita:BMC Public Health 2025 Feb 10; 25 (1) : 549.
Autor/es:Du, Yingqiang (a) Cai, Xingyou (b)
institución:(a) Department of Cardiology, Suzhou Municipal Hospital, Gusu School, the Affiliated Suzhou Hospital of Nanjing Medical University, Nanjing Medical University, Suzhou, Jiangsu Province, 215000, China. (b) Department of Cardiology, Suzhou Municipal Hospital, Gusu School, the Affiliated Suzhou Hospital of Nanjing Medical University, Nanjing Medical University, Suzhou, Jiangsu Province, 215000, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Incidence and risk factors for delayed intracranial hemorrhage after mild brain injury in anticoagulated patients: a multicenter retrospective study.
Incidence and risk factors for delayed intracranial hemorrhage after mild brain injury in anticoagulated patients: a multicenter retrospective study.
Fuente:Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Tipo de trabajo:Estudio de cohortes
Extracto:
Delayed ICH is uncommon among anticoagulated patients with mTBI and has minimal
impact on their outcome. Routine performance of a second CT scan may be
unnecessary and may be considered only in presence of high-risk clinical risk
factors or signs of deterioration.
Claves:Anticoagulants, Brain injuries, Cerebral hemorrhage, Emergency department
Cita:Scand J Trauma Resusc Emerg Med 2025 Feb 10; 33 (1) : 26.
Autor/es:Capsoni, Nicolò (a) Carpani, Giovanni (b)
institución:(a) School of Medicine and Surgery, University of Milan-Bicocca, Milan, Italy. n.capsoni@campus.unimib.it. (b) Department of Emergency Medicine, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy. n.capsoni@campus.unimib.it.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
The efficacy and safety of bivalirudin and heparin in patients with acute coronary syndrome
The efficacy and safety of bivalirudin and heparin in patients with acute coronary syndrome
Fuente:Systematic Reviews
Tipo de trabajo:Revisión sistemática
Extracto:
Compared with
heparin, bivalirudin has definite anticoagulant effect in patients with acute
myocardial infarction after PCI, and the risk of bleeding and the incidence of
retransfusion were lower in the bivalirudin group. This review helps doctors in
PCI management choose bivalirudin or heparin more precisely based on patients'
conditions for better treatment and fewer adverse events.
institución:(a) Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Dongzhimen Hospital, Beijing University of Chinese Medicine, Haiyuncang Lane 5, Dongcheng District, Beijing, 100700, China. zhaiyou036@163.com. (b) Henan University of Chinese Medicine, No. 156 Jinshui Road, Zhengzhou, Henan, 450046, China. zhaiyou036@163.com.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Exploring the Axis of Gut Microbiota-Inflammatory Cytokine-Atrial Fibrillation in the Pathogenesis of Atrial Fibrillation.
Exploring the Axis of Gut Microbiota-Inflammatory Cytokine-Atrial Fibrillation in the Pathogenesis of Atrial Fibrillation.
Fuente:Journal of Cellular and Molecular Medicine
Extracto:
These causal
associations and mediating effects are useful for managing AF through
manipulation of the gut microbiota.
Claves:atrial fibrillation, gut microbiota, inflammatory cytokine, mediation analysis, mendelian randomization
Cita:J Cell Mol Med 2025 Feb; 29 (3) : e70379.
Autor/es:Chen, Jun (a) Wang, Yucheng (b)
institución:(a) Department of Cardiology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Zhejiang, China. (b) Department of Cardiology, Zhongshan Hospital, Shanghai Institute of Cardiovascular Diseases, Shanghai Medical College of Fudan University, Shanghai, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Direct Current Stimulation (DCS) Modulates Lipid Metabolism and Intercellular Vesicular Trafficking in SHSY-5Y Cell Line: Implications for Parkinson's Disease.
Direct Current Stimulation (DCS) Modulates Lipid Metabolism and Intercellular Vesicular Trafficking in SHSY-5Y Cell Line: Implications for Parkinson's Disease.
Fuente:Journal of Neurochemistry
Extracto:
This may lead to a neuroprotective and
neuroplasticity-focussed transcriptional profile, potentially supporting the
therapeutic effects of tDCS at the cellular and molecular level in patients..
Claves:direct current stimulation (DCS), extracellular vesicles, inflammation, lipids, neurodegeneration, neuroplasticity
Cita:J Neurochem 2025 Feb; 169 (2) : e70014.
Autor/es:Piccoli, Marco (a) Barbato, Luisa (b)
institución:(a) Institute for Molecular and Translational Cardiology (IMTC), IRCCS Policlinico San Donato, Milan, Italy. (b) School of Medicine, University Vita-Salute San Raffaele, Milan, Italy.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Once-Weekly Semaglutide Versus Once-Daily Liraglutide for Weight Loss in Adults
Once-Weekly Semaglutide Versus Once-Daily Liraglutide for Weight Loss in Adults
Fuente:Clinical and Translational Science
Tipo de trabajo:Metanálisis
Extracto:
Once-weekly semaglutide
therapy results in a more pronounced loss in body weight, HbA1c, and fasting
glucose levels compared to once-daily liraglutide.
Claves:diabetes, metabolism, meta‐analysis, obesity, weight loss
institución:(a) Department of Medicine, Rawalpindi Medical University, Rawalpindi, Pakistan. (b) Department of Medicine, Rawalpindi Medical University, Rawalpindi, Pakistan.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Step Count Accuracy of the Life Plus Connected Watch at Different Localizations and Speeds in Healthy Adults, Patients With Cardiovascular Disease, and Patients With Peripheral Artery Disease: Step Count Validation Study in Laboratory Settings.
Step Count Accuracy of the Life Plus Connected Watch at Different Localizations and Speeds in Healthy Adults, Patients With Cardiovascular Disease, and Patients With Peripheral Artery Disease: Step Count Validation Study in Laboratory Settings.
Fuente:Jmir Formative Research
Extracto:
For optimized counting when worn at the wrist, healthy individuals
should prefer version 2 watches for slow walking (1.8 and 2.5 km/h) and version 3
for higher speeds (3.2 and 4 km/h). Patients (CVD and PAD) should prefer version
2 watches at 1.8 km/h and version 3 watches for higher speeds (2.5, 3.2, and 4
km/h).
Absence of Standard Modifiable Risk Factors in Middle Eastern Patients with Atherosclerotic Cardiovascular Disease. The Jordan Absence of Standard Modifiable Risk Factors (SMuRF-Less) Study.
Absence of Standard Modifiable Risk Factors in Middle Eastern Patients with Atherosclerotic Cardiovascular Disease. The Jordan Absence of Standard Modifiable Risk Factors (SMuRF-Less) Study.
Fuente:Vascular Health and Risk Management
Tipo de trabajo:Estudio clínico
Extracto:
In
this cohort of ME patients with ASCVD, nearly four in 100 were SMuRF-less. This
rate is lower than that reported by most of published studies, mainly due to the
high prevalence of the 4 SMuRFs. SMuRF-less patients were younger, had less
comorbid disease, received less secondary prevention pharmacotherapy and had
higher rate of one year mortality than those with SMuRFs. CLINICAL TRIALS: The
study is registered with ClinicalTrials.gov, unique identifier number
NCT06199869.
institución:(a) Department of Cardiology, Istishari Hospital, Amman, Jordan. (b) Department of Clinical Medical Sciences, Yarmouk University School of Medicine, Irbid, Jordan.
Conflicto:The work was presented in an abstract from at the American Heart Association congress in November 2024 and the poster’s abstract was published in “Circulation” in AHA/ASA Journals: http://www.ahajournals.org/doi/10.1161/circ. 150.suppl_1.4120131. The authors report no competing interests in this work.
Sexual and Cardiovascular health.Factors Influencing on the Quality of Sexual Life of Coronary Heart Disease Patients - a Narrative Review.
Sexual and Cardiovascular health.Factors Influencing on the Quality of Sexual Life of Coronary Heart Disease Patients - a Narrative Review.
Fuente:Vascular Health and Risk Management
Extracto:
Sexual
rehabilitation should be an integral part of cardiac rehabilitation, and
lifestyle modification and optimal treatment of underlying medical conditions are
key to maintaining psychophysical well-being and a successful sex life.
institución:(a) Department of Psychiatry, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Tarnowskie Gory, Poland. (b) Department of Psychoprophylaxis, Medical University of Silesia, Tarnowskie Góry, Poland.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Relationship between triglyceride glucose-body mass index baselines and variation with future cardiovascular diseases risk in the middle-aged and elderly individuals.
Relationship between triglyceride glucose-body mass index baselines and variation with future cardiovascular diseases risk in the middle-aged and elderly individuals.
Fuente:Frontiers in Endocrinology
Extracto:
Material changes in the TyG-BMI are independently associated with the risk of
CVDs in middle-aged and elderly individuals. Detecting long-term changes in the
TyG-BMI may aid in the early identification of high-risk individuals and help
prevent the occurrence of various cardiovascular diseases.
Claves:CHARLS, K-means clustering, cardiovascular disease, middle and elderly age, triglyceride glucose-body mass index
institución:(a) Department of Epidemiology and Health Statistics, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China. (b) Department of Epidemiology and Health Statistics, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
The U-shaped association of fasting plasma glucose to HbA1c ratio with mortality in diabetic and prediabetic populations: the mediating role of systemic immune-inflammation index.
The U-shaped association of fasting plasma glucose to HbA1c ratio with mortality in diabetic and prediabetic populations: the mediating role of systemic immune-inflammation index.
Fuente:Frontiers in Endocrinology
Extracto:
In the prospective cohort, the FPG/HbA1c ratio demonstrated a
U-shaped association with mortality in diabetic and prediabetic adults, with SII
playing a significant mediating role. These findings suggest that interventions
targeting immunity and inflammation may improve clinical outcomes in these
populations.
institución:(a) Department of Cardiovascular Medicine, Jiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College, Nanchang, Jiangxi, China. (b) Department of Cardiovascular Medicine, Jiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College, Nanchang, Jiangxi, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Autor/es:Nacanabo, Wendlassida Martin (a) Seghda, Taryètba André Arthur (b)
institución:(a) Service de cardiologie du Centre hospitalier universitaire de Bogodogo, Ouagadougou, Burkina Faso. (b) Service de cardiologie du Centre hospitalier universitaire de Bogodogo, Ouagadougou, Burkina Faso.
Cardiac computed tomography for cardiac masses: a necessity or a luxury?
Cardiac computed tomography for cardiac masses: a necessity or a luxury?
Fuente:The Journal of International Medical Research
Extracto:
With continued advances in CT technology, the integration of this modality into
routine clinical practice should improve the accuracy of diagnosis and management
of cardiac masses, strengthening the essential role of cardiac CT as a vital
component of contemporary cardiovascular imaging.
Cita:J Int Med Res 2025 Feb; 53 (2) : 3000605241306604.
Autor/es:Joudar, Imane (a) Nasri, Siham (b)
institución:(a) Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, Morocco. (b) Department of Radiology, Mohammed VI University Hospital Mohammed I University, Oujda, Morocco.
Conflicto:Declaration of conflicting interestThe authors declare that there is no conflict of interest.
Cardiac function and quality of life improvement with fasudil hydrochloride in patients with diabetes post-PCI: a randomized controlled trial.
Cardiac function and quality of life improvement with fasudil hydrochloride in patients with diabetes post-PCI: a randomized controlled trial.
Fuente:The Journal of International Medical Research
Tipo de trabajo:Estudio aleatorizado y controlado
Extracto:
Fasudil hydrochloride effectively
targets endothelial dysfunction and atherosclerosis, contributing to better
cardiac performance and metabolic regulation. These effects translate into
improved post-PCI quality of life for patients with diabetes and CHD. As an
adjunct to standard PCI therapy, fasudil hydrochloride treatment offers a
promising strategy for enhancing clinical outcomes in this high-risk patient
population.
Claves:Coronary heart disease, cardiac function, diabetes, fasudil hydrochloride, percutaneous coronary intervention, quality of life
Cita:J Int Med Res 2025 Feb; 53 (2) : 3000605241311403.
Autor/es:Yang, Xuejia (a) Li, Qian (b)
institución:(a) Cardiovascular Zone 2, North China Petroleum Administration General Hospital, Renqiu City, Hebei Province, China. (b) Cardiovascular Zone 2, North China Petroleum Administration General Hospital, Renqiu City, Hebei Province, China.
Conflicto:Declaration of conflicting interestThe authors declare that there is no conflict of interest.
Supportive care in cancer official journal of the Multinational Association of Supportive Care in Cancer
Selección SIIC: 13 Febrero, 2025
Supportive care in cancer official journal of the Multinational Association of Supportive Care in Cancer
Psychological burden, quality of life, problems, and parental concerns of single mothers with cancer: a cross-sectional comparison.
Psychological burden, quality of life, problems, and parental concerns of single mothers with cancer: a cross-sectional comparison.
Fuente:Supportive Care in Cancer Official Journal of The Multinational Association of Supportive Care in Cancer
Extracto:
In this sample,
the psychological burden of mothers with cancer who care for minor children did
not differ based on whether they were parenting alone or together with a
co-parent. However, SMs reported more practical problems and parental concerns
than PMs, emphasizing the need for targeted support in practical problem-solving
and child care for SMs. TRIAL REGISTRATION NUMBER: NCT04186923, 5. December 2019.
Claves:Distress, Minor children, Parent experience, Parental cancer, Psycho-onocology, Single mothers
Cita:Support Care Cancer 2025 Feb 11; 33 (3) : 173.
Autor/es:Holsteg, Steffen (a) Klett, Maike K (b)
institución:(a) Clinical Institute of Psychosomatic Medicine and Psychotherapy, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany. (b) Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), Düsseldorf, Germany.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
From Mechanisms to Management: Tackling In-Stent Restenosis in the Drug-Eluting Stent Era.
From Mechanisms to Management: Tackling In-Stent Restenosis in the Drug-Eluting Stent Era.
Fuente:Current Cardiology Reports
Tipo de trabajo:Revisión
Extracto:
Over time, treatment
strategies have evolved, and current guidelines recommend an individualized
approach using intracoronary imaging to characterize ISR's underlying substrate.
Autor/es:Spadafora, Luigi (a) Quarta, Rossella (b)
institución:(a) Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy. luigispadafora167@gmail.com. (b) Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Rende, Italy.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Integration and Potential Applications of Cardiovascular Computed Tomography in Cardio-Oncology.
Integration and Potential Applications of Cardiovascular Computed Tomography in Cardio-Oncology.
Fuente:Current Cardiology Reports
Tipo de trabajo:Revisión
Extracto:
Readily available
non-cardiac chest CT scans of patients with cancer may help with improved
cardiovascular care, enhanced ASCVD risk stratification and toxicity
surveillance.
Autor/es:Erbay, Muhammed Ibrahim (a) Manubolu, Venkat Sanjay (b)
institución:(a) Lundquist Institute at Harbor-UCLA Medical Center, Torrance, CA, USA. (b) Department of Medicine, Istanbul Cerrahpasa University, Istanbul, Türkiye.
Conflicto:Declarations. Human and Animal Rights and Informed Consent: This article does not contain any studies with human or animal subjects performed by any of the authors. Competing Interests: Maros Ferencik: Consulting: Siemens Healthineers, Elucid, HeartFlow, Cleerly, BioMarin; Advisory board: Cleerly; Stock options: Elucid. Matthew J. Budoff: Received grants from the following companies: Novo Nordisk, Novartis, AstraZeneca, HeartFlow, GE Healthcare, Amgen,...
and Boehringer Ingelheim, Department of Defense, Centers for Disease Contral, and the National Institutes of Health. Dr Budoff received honoraria from Novo Nordisk, Esperion, AstraZeneca, Merck, Janssen, and Eli Lilly. Eric H. Yang: Research funding/grants: CSL Behring, Boehringer Ingelheim, Eli and Lilly, Amgen, Bristol Myers Squibb, and Janssen Research and Development (all nonrelevant). Consulting fees: Xencor (nonrelevant) and Edwards Lifesciences. Speaker honoraria: Zoll Medical (nonrelevant) and National Cancer Comprehensive Cancer Center. The other authors declare that they have no conflict of interest.
