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The increasing number of Open Access articles widens the reading offer
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consult a profuse amount of documents that will feed
Authorized Full Texts (TCA, Spanish acronym).
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SIIC created, produced and handles the AFT software that deciphers
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While most of the selected texts belong to original articles,
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A 10-Year Risk Assessment and Primary Prevention Study of Atherosclerotic Cardiovascular Disease Among Adult Patients in Saudi Arabia: A Cross-Sectional Study.
A 10-Year Risk Assessment and Primary Prevention Study of Atherosclerotic Cardiovascular Disease Among Adult Patients in Saudi Arabia: A Cross-Sectional Study.
Fuente:Medicina (kaunas, Lithuania)
Extracto:
Modifiable risk
factors, including smoking, diabetes, and hypertension, combined with statin and
aspirin adherence, highlight critical areas for targeted interventions to reduce
the ASCVD burden in this population.
institución:(a) Family Medicine, Al-Ahsa Health Cluster, Alahsa 31982, Saudi Arabia. (b) Family Medicine and Geriatric Medicine, Al-Ahsa Health Cluster, Alahsa 31982, Saudi Arabia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Endothelial Dysfunction and Oxidative Stress in Patients with Severe Coronary Artery Disease: Does Diabetes Play a Contributing Role?
Endothelial Dysfunction and Oxidative Stress in Patients with Severe Coronary Artery Disease: Does Diabetes Play a Contributing Role?
Fuente:Medicina (kaunas, Lithuania)
Extracto:
5-HT receptor-targeted therapy might be of interest in patients undergoing CABG,
but further studies are needed to confirm this hypothesis.
Claves:CABG, diabetes, endothelial dysfunction, oxidative stress, severe coronary artery disease
Cita:Medicina (Kaunas) 2025 Jan 15; 61 (1)
Autor/es:Boieriu, Alexandra Maria (a) Luca, Cezar Dumitrel (b)
institución:(a) Faculty of Medicine, Transilvania University of Brasov, 500036 Braşov, Romania. (b) Department of Cardiology, Emergency County Hospital, 500036 Braşov, Romania.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Enhancing Therapy Adherence: Impact on Clinical Outcomes, Healthcare Costs, and Patient Quality of Life.
Enhancing Therapy Adherence: Impact on Clinical Outcomes, Healthcare Costs, and Patient Quality of Life.
Fuente:Medicina (kaunas, Lithuania)
Extracto:
Strengthening
adherence is not only crucial for individual patient outcomes, but also for
enhancing the sustainability and efficiency of healthcare systems.
Claves:adherence, clinical efficacy, healthcare costs, quality of life
institución:(a) School of Public Health, Centre of Postgraduate Medical Education of Warsaw, 01-813 Warsaw, Poland. (b) Departamento de Medicina Preventiva y Salud Pública, Universidad de Granada, 18012 Granada, Spain.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Special Issue: "New Trends in Diabetes, Hypertension, and Cardiovascular Diseases-2nd Edition".
Special Issue: "New Trends in Diabetes, Hypertension, and Cardiovascular Diseases-2nd Edition".
Fuente:International Journal of Molecular Sciences
Extracto:
ardiovascular diseases (CVDs) encompass a range of conditions affecting both the
heart (e.g., coronary heart disease and heart failure [1]) and blood vessels
(e.g., cerebrovascular disease [2] and peripheral artery disease [3]) [...].
Cita:Int J Mol Sci 2025 Jan 7; 26 (2)
Autor/es:Wang, Yutang (a) Magliano, Dianna J (b)
institución:(a) Discipline of Life Science, Institute of Innovation, Science and Sustainability, Federation University Australia, Ballarat, VIC 3353, Australia. (b) Diabetes and Population Health, Baker Heart and Diabetes Institute, Melbourne, VIC 3004, Australia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Evaluation of Structure Prediction and Molecular Docking Tools for Therapeutic Peptides in Clinical Use and Trials Targeting Coronary Artery Disease.
Evaluation of Structure Prediction and Molecular Docking Tools for Therapeutic Peptides in Clinical Use and Trials Targeting Coronary Artery Disease.
Fuente:International Journal of Molecular Sciences
Extracto:
Future work should focus on in vivo validation and
combination therapies to fully explore the clinical potential of these
therapeutic peptides.
institución:(a) Health Sciences Research Center (HSRC), Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 13317, Saudi Arabia. (b) Department of Applied Biotechnology, Faculty of Chemistry, Warsaw University of Technology, 00-661 Warsaw, Poland.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Endothelial Dysfunction and Hemostatic System Activation in Relation to Shift Workers, Social Jetlag, and Chronotype in Female Nurses.
Endothelial Dysfunction and Hemostatic System Activation in Relation to Shift Workers, Social Jetlag, and Chronotype in Female Nurses.
Fuente:International Journal of Molecular Sciences
Extracto:
Further research is needed to evaluate inhibitors of heparanase to attenuate the
thrombotic risk in individuals with circadian misalignment.
Claves:chronotype, coagulation, endothelial dysfunction, shift workers, social jetlag
Cita:Int J Mol Sci 2025 Jan 8; 26 (2)
Autor/es:Saharov, Gleb (a) Salti, Barbara (b)
institución:(a) Thrombosis and Hemostasis Unit, Rambam Health Care Campus, Haifa 3109601, Israel. (b) Department of Nursing, Faculty of Social Welfare and Health Sciences, University of Haifa, Haifa 3109601, Israel.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Residual Traditional Risk in Non-Traditional Atherosclerotic Diseases.
Residual Traditional Risk in Non-Traditional Atherosclerotic Diseases.
Fuente:International Journal of Molecular Sciences
Extracto:
We advocate for future research to focus on developing innovative,
disease-specific CV risk assessment tools that incorporate non-traditional risk
factors, recognizing this as a promising avenue for translational and clinical
outcome research.
institución:(a) Cardiovascular Internal Medicine Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Roma, Italy. (b) Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, 00168 Roma, Italy.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Autor/es:Wojciechowska, Małgorzata (a) Nizio, Michał (b)
institución:(a) Chair and Department of Experimental and Clinical Physiology, Laboratory of Centre for Preclinical Research, Medical University of Warsaw, 02-097 Warsaw, Poland. (b) Chair and Department of Experimental and Clinical Physiology, Laboratory of Centre for Preclinical Research, Medical University of Warsaw, 02-097 Warsaw, Poland.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Enrichment of RedoxifibromiR miR-21-5p in Plasma Exosomes of Hypertensive Patients with Renal Injury.
Enrichment of RedoxifibromiR miR-21-5p in Plasma Exosomes of Hypertensive Patients with Renal Injury.
Fuente:International Journal of Molecular Sciences
Extracto:
miR-21-5p, such as a RedoxifibromiR, has a significant accuracy for
discriminating renal damage and is closely related with relevant signalling
pathways implicated in fibrogenesis in podocytes.
Autor/es:Martinez-Arroyo, Olga (a) Flores-Chova, Ana (b)
institución:(a) Cardiometabolic and Renal Risk Research Group, INCLIVA Biomedical Research Institute, 46010 Valencia, Spain. (b) Cardiometabolic and Renal Risk Research Group, INCLIVA Biomedical Research Institute, 46010 Valencia, Spain.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Characterizing SV40-hTERT Immortalized Human Lung Microvascular Endothelial Cells as Model System for Mechanical Stretch-Induced Lung Injury.
Characterizing SV40-hTERT Immortalized Human Lung Microvascular Endothelial Cells as Model System for Mechanical Stretch-Induced Lung Injury.
Fuente:International Journal of Molecular Sciences
Extracto:
This study provides an unprecedented and
detailed characterization of the HLMVEC/SVTERT289 cell line, which should help to
appraise its suitability in different molecular studies.
institución:(a) Clinical Division of General Anaesthesia and Intensive Care Medicine, Department of Anesthesia, Genera Intensive Care and Pain Therapy, Medical University Vienna, 1090 Vienna, Austria. (b) Evercyte GmbH, 1110 Vienna, Austria.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Acute Severe Hypoxia Decreases Mitochondrial Chain Complex II Respiration in Human Peripheral Blood Mononuclear Cells.
Acute Severe Hypoxia Decreases Mitochondrial Chain Complex II Respiration in Human Peripheral Blood Mononuclear Cells.
Fuente:International Journal of Molecular Sciences
Extracto:
These results support further studies investigating whether modulation of
complex II activity might modify the inflammatory and metabolic alterations
observed in heart failure.
institución:(a) Biomedicine Research Center of Strasbourg (CRBS), UR 3072, "Mitochondria, Oxidative Stress and Muscle Plasticity", Faculty of Medicine, University of Strasbourg, 67000 Strasbourg, France. (b) Department of Physiology and Functional Explorations, University Hospital of Strasbourg, 67091 Strasbourg, France.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Fecal Microbiota Strongly Correlates with Tissue Microbiota Composition in Colorectal Cancer but Not in Non-Small Cell Lung Cancer.
Fecal Microbiota Strongly Correlates with Tissue Microbiota Composition in Colorectal Cancer but Not in Non-Small Cell Lung Cancer.
Fuente:International Journal of Molecular Sciences
Extracto:
Furthermore, our data demonstrate that the microbiota components of tumor and
non-tumor tissues are similar, with only minor differences being detected.
Claves:colorectal cancer, microbiota, non-small cell lung cancer
Cita:Int J Mol Sci 2025 Jan 16; 26 (2)
Autor/es:Vicente-Valor, Juan (a) Tesolato, Sofía (b)
institución:(a) Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Complutense University, 28040 Madrid, Spain. (b) San Carlos Health Research Institute (IdISSC), 28040 Madrid, Spain.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
MicroRNA Expression Profile in Acute Ischemic Stroke.
MicroRNA Expression Profile in Acute Ischemic Stroke.
Fuente:International Journal of Molecular Sciences
Tipo de trabajo:Revisión
Extracto:
Additionally, investigations are needed to assess the prognostic
relevance of these miRNAs by linking their expression profiles with radiological
and functional outcomes.
institución:(a) Department of Neurology, Virginia Commonwealth University, Richmond, VA 23298, USA. (b) Department of Internal Medicine, Maharajgunj Medical Campus, Tribhuvan University, Kathmandu 44600, Nepal.
Conflicto:(1) Shraddha Mainali: Has received funding support from Ohio State University Neuroscience Research Institute for this pilot study. Has received funding from the Center for Clinical and Translational Science at The Ohio State University sponsored by the National Center for Advancing Translational Sciences (UL1TR002733). Has received research consultation fees from Marinus Pharmaceuticals. (2) Nicholas E. Johnson: Has received grant funding...
from NINDS (R01NS104010, U01NS124974), NCATS (R21TR003184), CDC (U01DD001242), and the FDA (2R01FD006071). He receives royalties from the CCMDHI and the CMTHI. He receives research funds from Avidity, Takeda, Sanofi Genzyme, Dyne, Novartis, Vertex Pharmaceuticals, Fulcrum Therapeutics, ML Bio, and Sarepta. He has provided consultation for Arthex, Novartis, AMO Pharma, Takeda, Design, Dyne, Avidity, Rgenta, and Vertex Pharmaceuticals. Remaining authors: GN, AW, PF, DM, MH, PS, BW, and DW report no relevant disclosures.
FLAME: Training and Validating a Newly Conceived Model Incorporating Alpha-Glutathione-S-Transferase Serum Levels for Predicting Advanced Hepatic Fibrosis and Acute Cardiovascular Events in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD).
FLAME: Training and Validating a Newly Conceived Model Incorporating Alpha-Glutathione-S-Transferase Serum Levels for Predicting Advanced Hepatic Fibrosis and Acute Cardiovascular Events in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD).
Fuente:International Journal of Molecular Sciences
Extracto:
FLAME represents a novel tool that
accurately predicts AF and ACEs in MASLD.
Claves:biomarkers, fatty liver, liver cirrhosis
Cita:Int J Mol Sci 2025 Jan 17; 26 (2)
Autor/es:Dallio, Marcello (a) Romeo, Mario (b)
institución:(a) Hepatogastroenterology Division, Department of Precision Medicine, University of Campania Luigi Vanvitelli, Piazza Miraglia 2, 80138 Naples, Italy. (b) Hepatogastroenterology Division, Department of Precision Medicine, University of Campania Luigi Vanvitelli, Piazza Miraglia 2, 80138 Naples, Italy.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Vascular Cell Adhesion Molecule 1 and E-Selectin as Potential Cardiovascular Risk Biomarkers in Psoriasis.
Vascular Cell Adhesion Molecule 1 and E-Selectin as Potential Cardiovascular Risk Biomarkers in Psoriasis.
Fuente:International Journal of Molecular Sciences
Extracto:
The shared mechanisms of psoriasis and
atherosclerosis, along with the effect of treatments on endothelial activation
markers, provide significant insights for further research and approaches to
manage inflammatory diseases in the future.
institución:(a) School of Medicine, Collegium Medicum, University of Warmia and Mazury, 10-082 Olsztyn, Poland. (b) Department of Dermatology, Sexually Transmitted Diseases and Clinical Immunology, Collegium Medicum, University of Warmia and Mazury, Al. Wojska Polskiego 30, 10-229 Olsztyn, Poland.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Thiamine and Thiamine Pyrophosphate as Non-Competitive Inhibitors of Acetylcholinesterase-Experimental and Theoretical Investigations.
Thiamine and Thiamine Pyrophosphate as Non-Competitive Inhibitors of Acetylcholinesterase-Experimental and Theoretical Investigations.
Fuente:Molecules (basel, Switzerland)
Extracto:
The
results of the current study indicate a non-competitive type of enzyme
inhibition, in contrast to the previously published works suggesting a
competitive one.
Autor/es:Szeleszczuk, Łukasz (a) Pisklak, Dariusz Maciej (b)
institución:(a) Department of Organic and Physical Chemistry, Medical University of Warsaw, 1 Banacha Str., 02-097 Warsaw, Poland. (b) Department of Organic and Physical Chemistry, Medical University of Warsaw, 1 Banacha Str., 02-097 Warsaw, Poland.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Nighttime Cough Characteristics in Chronic Obstructive Pulmonary Disease Patients.
Nighttime Cough Characteristics in Chronic Obstructive Pulmonary Disease Patients.
Fuente:Sensors (basel, Switzerland)
Extracto:
An alert mechanism
incorporating these findings is described.
Claves:COPD, acute exacerbation, alert, cough
Cita:Sensors (Basel) 2025 Jan 11; 25 (2)
Autor/es:den Brinker, Albertus C (a) Ouweltjes, Okke (b)
institución:(a) Independent Researcher, 5708 DJ Helmond, The Netherlands. (b) Philips Digital Standardization & Licensing Research, 5656 AE Eindhoven, The Netherlands.
Conflicto:A. H. Morice, M.G. Crooks and S. Thackray-Nocera report that financial support was provided by Philips Innovation Hub Eindhoven. O. Ouweltjes and R. Rietman are employees at Philips.
Impact of Time-Restricted Eating and High-Intensity Exercise on Nutrient Intake in Women with Overweight/Obesity: Secondary Analysis of a Randomized Controlled Trial.
Impact of Time-Restricted Eating and High-Intensity Exercise on Nutrient Intake in Women with Overweight/Obesity: Secondary Analysis of a Randomized Controlled Trial.
Fuente:Nutrients
Tipo de trabajo:Estudio aleatorizado y controlado
Extracto:
A ≤10-h
TRE window might increase the risk of micronutrient inadequacy in women with
overweight/obesity. Future research is needed to investigate the effects of
integrating nutritional guidelines with TRE interventions to mitigate the risk of
micronutrient inadequacy in individuals with overweight/obesity.
Autor/es:Haganes, Kamilla L (a) Devlin, Brooke L (b)
institución:(a) Department of Circulation and Medical Imaging, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, 7491 Trondheim, Norway. (b) Women's Clinic, St. Olav's Hospital, 7006 Trondheim, Norway.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Effects of Quercetin and Citrulline on Nitric Oxide Metabolites and Antioxidant Biomarkers in Trained Cyclists.
Effects of Quercetin and Citrulline on Nitric Oxide Metabolites and Antioxidant Biomarkers in Trained Cyclists.
Fuente:Nutrients
Extracto:
These findings
suggest that combined and independent QCT and CIT supplementation did not
significantly improve these biomarkers, suggesting that baseline training
adaptations, supplementation timing, and individual variability may influence the
efficacy of these compounds in enhancing exercise performance and oxidative
stress markers. The ergogenic efficacy of QCT + CIT on antioxidant-related
markers remains inconclusive.
Autor/es:Kurtz, Jennifer A (a) Feresin, Rafaela G (b)
institución:(a) Department of Public Health & Exercise Science, Appalachian State University, Boone, NC 28607, USA. (b) Department of Nutrition, Georgia State University, Atlanta, GA 30203, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Magnesium Depletion Score and Mortality in Individuals with Metabolic Dysfunction Associated Steatotic Liver Disease over a Median Follow-Up of 26 Years.
Magnesium Depletion Score and Mortality in Individuals with Metabolic Dysfunction Associated Steatotic Liver Disease over a Median Follow-Up of 26 Years.
Fuente:Nutrients
Extracto:
In individuals with MASLD or MetALD, higher MDS, indicative of worse global Mg
status, was associated with an increased risk of all-cause and CVD mortality.
Correcting global Mg deficiency in high-risk MASLD/MetALD patients may have
long-term health benefits.
institución:(a) Vanderbilt Memory and Alzheimer's Center, Vanderbilt University School of Medicine, Nashville, TN 37203, USA. (b) Department of Neurology, Vanderbilt University Medical Center, Nashville, TN 37203, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
