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Clinical Outcomes and Safety Profiles of Generic Versus Brand-Name Clopidogrel in Patients Following Coronary Artery Stent Placement.
Clinical Outcomes and Safety Profiles of Generic Versus Brand-Name Clopidogrel in Patients Following Coronary Artery Stent Placement.
Fuente:Clinical and Translational Science
Extracto:
In conclusion, among patients undergoing coronary stenting,
the risks of ischemic and bleeding events were comparable between those receiving
generic and brand-name clopidogrel.
institución:(a) The Cardiovascular Department, Chang Gung Memorial Hospital, Taoyuan, Taiwan. (b) The Cardiovascular Department, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Respiratory syncytial virus vaccination in older adults and patients with chronic disorders: A position paper from the Portuguese Society of Pulmonology, the Portuguese Association of General and Family Medicine, the Portuguese Society of Cardiology, the Portuguese Society of Infectious Diseases and Clinical Microbiology, the Portuguese Society of Endocrinology, Diabetes and Metabolism, and the Portuguese Society of Internal Medicine.
Respiratory syncytial virus vaccination in older adults and patients with chronic disorders: A position paper from the Portuguese Society of Pulmonology, the Portuguese Association of General and Family Medicine, the Portuguese Society of Cardiology, the Portuguese Society of Infectious Diseases and Clinical Microbiology, the Portuguese Society of Endocrinology, Diabetes and Metabolism, and the Portuguese Society of Internal Medicine.
Fuente:Pulmonology
Extracto:
The RSV vaccine is
recommended for people aged ≥50 years with risk factors (chronic obstructive
pulmonary disease, asthma, heart failure, coronary artery disease, diabetes,
chronic kidney disease, chronic liver disease, immunocompromise, frailty,
dementia, and residence in a nursing home) and all persons aged ≥60 years. If it
cannot be made available to this population, then the vaccine should be
prioritised for individuals aged ≥75 years and those aged ≥50 years with risk
factors. The vaccine should preferably be given between September and November
and can be co-administered with the influenza vaccine. Ongoing studies on RSV
vaccines may justify extending these recommendations in the future.
institución:(a) Portuguese Society of Pulmonology (SPP), Lisbon, Portugal. (b) Department of Pulmonology, Unidade Local de Saúde de Coimbra, E.P.E, Coimbra, Portugal.
Genomic characteristics and molecular epidemiology of MRSA from medical centers in Mexico: Results from the Invifar network.
Genomic characteristics and molecular epidemiology of MRSA from medical centers in Mexico: Results from the Invifar network.
Fuente:Plos One
Extracto:
In this
study, the most frequently detected CC was CC5, followed by CC8, and CC93, and
the most frequently detected MRSA ST was ST1011, followed by ST5. Most SCCmec
elements were found to be type IIa, followed by type IVa. High MIC values were
observed for ciprofloxacin, erythromycin, and clindamycin, particularly within
SCCmec IIa. Of the SCCmec IVa strains, most harbored the lukS-PV and lukF-PV
genes.
Cita:PLoS One 2025; 20 (1) : e0317284.
Autor/es:Echaniz-Avilés, Gabriela (a) Núñez-García, Luis Ángel (b)
institución:(a) Centro de Investigación Sobre Enfermedades Infecciosas, Instituto Nacional de Salud Pública, Cuernavaca, Morelos, Mexico. (b) Departamento de Bioquímica y Medicina Molecular, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Developing Assessments for Key Stakeholders in Pediatric Congenital Heart Disease: Qualitative Pilot Study to Inform Designing of a Medical Education Toy.
Developing Assessments for Key Stakeholders in Pediatric Congenital Heart Disease: Qualitative Pilot Study to Inform Designing of a Medical Education Toy.
Fuente:Jmir Formative Research
Tipo de trabajo:Revisión
Extracto:
This
pilot study emphasizes the importance of iterative assessment development,
focusing on multistakeholder engagement. The insights gained from the development
process will guide the creation of tailored assessments and inform the
development of child-led educational interventions for pediatric populations with
CHD.
Claves:assessment, caregiving, children health, children health literacy, congenital heart disease, design, educational interventions, health education, patient-centered care, qualitative pilot
Cita:JMIR Form Res 2025 Jan 27; 9 : e63818.
Autor/es:Barbazi, Neda (a) Shin, Ji Youn (b)
institución:(a) Department of Design Innovation, College of Design, University of Minnesota, Twin Cities, Minneapolis, MN, United States. (b) Department of Design Innovation, College of Design, University of Minnesota, Twin Cities, Minneapolis, MN, United States.
Knowledge, attitudes and practices of intensive care unit physicians towards the management of acute respiratory distress syndrome in China: a cross-sectional survey.
Knowledge, attitudes and practices of intensive care unit physicians towards the management of acute respiratory distress syndrome in China: a cross-sectional survey.
Fuente:Bmj Open
Extracto:
ICU physicians in China exhibited inadequate knowledge, moderate
attitudes and suboptimal practices regarding ARDS management. Enhancing education
and work experience is crucial, along with practical, scenario-based training, to
improve KAP in ARDS management.
institución:(a) Department of Critical Care Medicine, The First Affiliated Hospital of Guangxi Medical University; Guangxi Clinical Research Center for Critical Care Medicine, Nanning, Guangxi Zhuang Autonomous Region, People's Republic of China. (b) Department of Critical Care Medicine, The First Affiliated Hospital of Guangxi Medical University; Guangxi Clinical Research Center for Critical Care Medicine, Nanning, Guangxi Zhuang Autonomous Region, People's Republic of China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Patients with neurological or psychiatric complications of COVID-19 have worse long-term functional outcomes
Patients with neurological or psychiatric complications of COVID-19 have worse long-term functional outcomes
Fuente:Scientific Reports
Tipo de trabajo:Estudio multicéntrico
Extracto:
Female sex, age > 50 years, and hypertension were
associated with worse outcomes, and statins or ACE inhibitors with better
outcomes.
Cita:Sci Rep 2025 Jan 27; 15 (1) : 3443.
Autor/es:Shil, Rajish S K (a) Seed, Adam (b)
institución:(a) Clinical Infection, Microbiology & Immunology, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK. rajishsk@liverpool.ac.uk. (b) Department of Neurology, Walton Centre of Neurosurgery and Neurology, Liverpool, UK. rajishsk@liverpool.ac.uk.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Factors associated with post-traumatic stress symptoms in healthcare providers after performance of cardiopulmonary resuscitation: a mixed-methods study.
Factors associated with post-traumatic stress symptoms in healthcare providers after performance of cardiopulmonary resuscitation: a mixed-methods study.
Fuente:Scientific Reports
Extracto:
Therefore, to avoid or overcome PTSD caused by performing
CPR, systematic and customized intervention strategies suitable for each stage of
the process are needed.
institución:(a) Department of emergency medicine, College of Medicine, Chung-Ang University, 84 Heukseok-ro, Dongjak-gu, 06974, Seoul, Republic of Korea. (b) Emergency Medicine, Chung-Ang University Gwangmyeong Hospital, 110 Deokan-ro, Gwangmyeong-si, 14353, Gyeonggi-do, Republic of Korea.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Antihypertensive drug-related problems in Vietnamese ambulatory care.
Antihypertensive drug-related problems in Vietnamese ambulatory care.
Fuente:Scientific Reports
Extracto:
These findings
could improve DRP alerts and maximize treatment outcomes in Asian patients with
hypertension.
Claves:Ambulatory care, Drug-related problem, Hypertension, Vietnam
Cita:Sci Rep 2025 Jan 27; 15 (1) : 3378.
Autor/es:Nguyen, Hoang Hai (a) Vu, Le Anh Thu (b)
institución:(a) Department of Cardiology, Nhan Dan Gia Dinh Hospital, Ho Chi Minh City, Vietnam. (b) Faculty of Pharmacy, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Conflicto:Declarations. Competing interests: M-HT reported receiving travel reimbursement from Pfizer Vietnam Ltd, speaking fees and grants from Servier Vietnam Ltd outside the submitted work. HTP reported receiving speaking fees and travel reimbursement from Servier Vietnam Ltd and Pfizer Vietnam Ltd, grants from Servier Vietnam Ltd outside the submitted work. The remaining authors declare no competing interest. Ethics approval and consent...
to participate: This study was approved by the Institutional Review Board (IRB) of the University of Medicine and Pharmacy at Ho Chi Minh City (Vietnam; approval number 611/HDDD-DHYD; November 11, 2021) and was conducted in accordance with the Declaration of Helsinki. Informed consent was not required for this study, as determined by the IRB of the University of Medicine and Pharmacy at Ho Chi Minh City, since we only collected retrospective data from medical records without revealing patient or physician identity.
The lean body mass to visceral fat mass ratio is negatively associated with cardiometabolic disorders: a cross-sectional study.
The lean body mass to visceral fat mass ratio is negatively associated with cardiometabolic disorders: a cross-sectional study.
Fuente:Scientific Reports
Extracto:
Maintaining an appropriate ratio of LMI to VFMI
may be associated with favorable metabolic health.
Claves:Cardiometabolic disorders, Diabetes, Dyslipidemia, Hypertension, Lean body mass, Visceral fat mass
Cita:Sci Rep 2025 Jan 27; 15 (1) : 3422.
Autor/es:Shao, Ya (a) Wang, Na (b)
institución:(a) Health Management Center, TaiHe Hospital, Hubei University of Medicine, Wudangshan Campus, Shiyan, Hubei, China. (b) Innovation Centre of Nursing Research, TaiHe Hospital, Hubei University of Medicine, Shiyan, Hubei, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Centre for Endocrine and Thyroid Diseases, Deyang People's Hospital, Deyang, 618000, China. (b) Department of Endocrinology and Metabolism, Affiliated Hospital of Southwest Medical University, Luzhou, 646000, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Exposure to major coronary heart disease events reduces lung cancer risk: a mendelian randomization study based on a European population.
Exposure to major coronary heart disease events reduces lung cancer risk: a mendelian randomization study based on a European population.
Fuente:Bmc Cancer
Extracto:
This study suggests that MCHDE reduce
the risk of NSCLC in the U.K. population and SCLC in the Finnish population.
However, given that the underlying mechanism through which MCHDE reduces the risk
of NSCLC and SCLC remains unclear, it is premature to conclude that individuals
exposed to MCHDE do not require lung cancer screening.
Claves:Lung cancer, Major coronary heart disease events, Mendelian randomization
Cita:BMC Cancer 2025 Jan 27; 25 (1) : 152.
Autor/es:He, Dongming (a) Lu, Hongting (b)
institución:(a) Department of Thoracic and Cardiovascular Surgery, The First Affiliated Hospital of Guangxi Medical University, Guangxi Zhuang Autonomous Region, Nanning, 530021, P. R. China. (b) Department of Thoracic and Cardiovascular Surgery, The First Affiliated Hospital of Guangxi Medical University, Guangxi Zhuang Autonomous Region, Nanning, 530021, P. R. China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Association of elevated albumin-corrected anion gap with all-cause mortality risk in atrial fibrillation: a retrospective study.
Association of elevated albumin-corrected anion gap with all-cause mortality risk in atrial fibrillation: a retrospective study.
Fuente:Bmc Cardiovascular Disorders
Extracto:
In individuals with
AF, higher ACAG levels are related to a greater mortality risk at 30 and 365
days. These findings suggest that ACAG may serve as a valuable prognostic marker
for AF patient stratification. Incorporating ACAG into clinical decision-making
could support improved therapeutic strategies and enhance patient outcomes.
Claves:Albumin-corrected anion gap, Atrial fibrillation, Intensive care unit, Mortality, Retrospective analysis
Cita:BMC Cardiovasc Disord 2025 Jan 27; 25 (1) : 55.
Autor/es:Xu, Jia (a) Wang, Zhen (b)
institución:(a) Department of Electrocardiography Diagnosis, The Second Affiliated Hospital of Anhui Medical University, 678 Furong Road, Anhui, 230601, China. (b) Department of Cardiovascular Diseases, The Second Affiliated Hospital of Anhui Medical University, 678 Furong Road, Hefei, 230601, Anhui, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Facilitating active participation in anticoagulant decisions in advanced kidney disease: co-production of a question prompt list.
Facilitating active participation in anticoagulant decisions in advanced kidney disease: co-production of a question prompt list.
Fuente:Bmc Nephrology
Tipo de trabajo:Guía
Extracto:
Shared-decision making is
important when initiating medication to ensure the best outcomes for patients,
yet it can be difficult to engage in shared-decision making without prompts or
guidance. This co-produced question prompt list could be included as part of
national guideline to support shared-decision making for anticoagulant initiation
in patients with advanced chronic kidney disease.
Claves:Anticoagulation, Chronic Kidney Diease, Co-production, Patient involvement, Shared-decision making
institución:(a) Division of Pharmacy and Optometry, School of Health Sciences, The University of Manchester, University of Manchester, Manchester, M13 9PT, UK. kathrine.parker@postgrad.manchester.ac.uk. (b) Manchester Institute of Nephrology and Transplantation, Manchester University NHS Foundation Trust, Oxford Road, Manchester, M13 9WL, UK. kathrine.parker@postgrad.manchester.ac.uk.
Conflicto:Declarations. Ethics approval and consent to participate: Ethical approval for this study was granted by North-West - Greater Manchester Central Research Ethics Committee. REC reference: 21/NW/0180. Informed consent was obtained from all subjects prior to their participation in the study. Consent for publication: NA. Competing interests: Within the last 3 years KP has received honoraria from Bayer, AstraZeneca, GlaxoSmithKline, Astellas...
and Vifor Pharma. JT has received honoraria from Bayer, Boehringer Ingelheim, BMS-Pfizer, Daichi-Sankyo, Octapharma, Leo Pharma. PL, SM, AN and SM have no competing interests to declare.
Associations of sedentary time, sleep duration and physical exercise with multimorbidity among older adults in Shanghai, China: a cross-sectional study based on national physical fitness surveillance data.
Associations of sedentary time, sleep duration and physical exercise with multimorbidity among older adults in Shanghai, China: a cross-sectional study based on national physical fitness surveillance data.
Fuente:Bmc Geriatrics
Extracto:
Over 40% of older
adults in Shanghai, China, suffer from multimorbidity. Prolonged sedentary
behavior and shorter sleep duration were associated with membership in the
metabolic-cardiovascular-joint-digestive-respiratory disease class, the
metabolic-cardiovascular disease class, and the joint-digestive-respiratory
disease class. Physical exercise showed varying degrees of protection against
these 3 multimorbidity patterns, with special attention warranted for LIPE.
Identifying the relationship between determinants of lifestyle behavior and
patterns of multimorbidity can help develop more targeted prevention and
management strategies.
institución:(a) Department of Health Economics, School of Public Health, Fudan University, 130 Dong'an Road, Shanghai, 200032, China. (b) Key Laboratory of Health Technology Assessment (Fudan University), National Health Commission, 130 Dong'an Road, Shanghai, 200032, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Trend of the lipid profile in a cohort with severe hypercholesterolemia in Osona county (Barcelona, Spain), between 2009 and 2021.
Trend of the lipid profile in a cohort with severe hypercholesterolemia in Osona county (Barcelona, Spain), between 2009 and 2021.
Fuente:Bmc Public Health
Tipo de trabajo:Guía
Extracto:
Three out of four cases failed to reduce the levels of LDL-C and
non-HDL-C, recommended by the guidelines of scientific societies. Primary Care is
the ideal framework to implement improvement strategies to control severe
hypercholesterolemia, and it is therefore essential to strengthen it.
Claves:Cardiovascular disease, Lipid-lowering treatment, Primary care, Severe hypercholesterolemia
Cita:BMC Public Health 2025 Jan 27; 25 (1) : 331.
Autor/es:Prat-Quinzaños, Jordi (a) Deniel-Rosanas, Joan (b)
institución:(a) Laboratory Medicine, Clinical Laboratory, Vic University Hospital, Vic, Barcelona, Spain. (b) Family and Community Medicine, Manlleu Primary Care Centre, Manlleu, Barcelona, Spain. joandeniel@camfic.org.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Impact of family socio-economic status on the prognosis of heart transplantation in children.
Impact of family socio-economic status on the prognosis of heart transplantation in children.
Fuente:Bmc Public Health
Extracto:
Lower family socio-economic status is associated with a worse
prognosis than high family socio-economic status. Measures to alleviate economic
disparities are needed to improve the prognosis of pediatric HTx.
Claves:Children, Heart transplantation, Prognosis, Socio-economic status
Cita:BMC Public Health 2025 Jan 27; 25 (1) : 335.
Autor/es:Liu, Shun (a) Mo, Han (b)
institución:(a) Department of Cardiac Surgery, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, 167A Beilishi Road, Xi Cheng District, Beijing, 100037, China. (b) State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Effectiveness of deliberate practices versus conventional lecture in trauma training for medical students.
Effectiveness of deliberate practices versus conventional lecture in trauma training for medical students.
Fuente:Bmc Medical Education
Tipo de trabajo:Estudio aleatorizado y controlado
Extracto:
Deliberate practice is significantly more effective than the
conventional lecture method in teaching life-threatening trauma procedures to
medical students. The implication of these findings is that implementing
deliberate practice in medical education can enhance the competencies of
students, improve their preparedness for real-world clinical settings, and
produce better patient outcomes. However, future research should examine the
broader applications and long-term benefits of this method in medical training.
TRIAL REGISTRATION: TCTR20240816009.
Claves:Deliberate practice, Medical student, Trauma training
Cita:BMC Med Educ 2025 Jan 28; 25 (1) : 130.
Autor/es:Kanoksin, Suksan (a) Songkhla, Bhapapak Na (b)
institución:(a) Cardiovascular and Thoracic Surgery Unit, Department of Surgery, School of Health Science, Faculty of Health Science Technology, Chulabhorn Hospital & Paramedic Program, Chulabhorn Royal Academy Bangkok, Bangkok, Thailand. (b) Department of Surgery, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok, Thailand.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Effect of census-based correction of population figures on mortality rates in Germany.
Effect of census-based correction of population figures on mortality rates in Germany.
Fuente:Population Health Metrics
Extracto:
Even though the
Census 2011 corrected nationwide mortality rates without age stratification
differed only slightly from the uncorrected rates, there were noticeable
increases in mortality, particularly in the city states of Hamburg and Berlin and
in old age. Due to the particularly large error in the population figures in the
older age range, an age standard that assigns lower weights at older ages should
be used for age standardization of rates wherever possible.
Cita:Popul Health Metr 2025 Jan 28; 23 (1) : 1.
Autor/es:Stang, Andreas (a) Deckert, Markus (b)
institución:(a) Institute of Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Hufelandstr. 55, 45147, Essen, Germany. imibe.dir@uk-essen.de. (b) School of Public Health, Department of Epidemiology, Boston University, 715 Albany Street, Talbot Building, Boston, MA, 02118, USA. imibe.dir@uk-essen.de.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Does diabetes modify the triglyceride-glucose index associated with cardiovascular events and mortality? A meta-analysis of 50 cohorts involving 7,239,790 participants.
Does diabetes modify the triglyceride-glucose index associated with cardiovascular events and mortality? A meta-analysis of 50 cohorts involving 7,239,790 participants.
Fuente:Cardiovascular Diabetology
Extracto:
TyG index showed
association with cardiovascular events, mortality, and all-cause mortality
independent of diabetic status, with low to moderate certainty. The associations
for IHD and all-cause death were stronger in diabetic patients than in
individuals without diabetes. Future studies should explore the role of diabetes
in the TyG index-associated CVD outcomes and mortality.
Claves:Cardiovascular disease, Diabetes mellitus, Meta-analysis, Mortality, Triglyceride–glucose index
Cita:Cardiovasc Diabetol 2025 Jan 27; 24 (1) : 42.
Autor/es:Zhang, Jun (a) Zhan, Qiye (b)
institución:(a) Department of Cardiology, Affiliated Hospital of Jiujiang University, Jiujiang, China. (b) Jiujiang Clinical Precision Medicine Research Center, Jiujiang, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación