ANTILEUKEMIA ACTIVITIES OF RETINOID AND ARSENIC
All-trans retinoic acid and arsenic trioxide are recently recognized as effective agents to treat acute promyelocytic leukemia. These two agents reduce leukemia cells followed by affecting the function of the PML-RAR alpha, an unusual molecule as a result of the t(15;17) chromosomal translocation.

Takeaki Nitto
Yokohama, Jp

  

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  TRATAMIENTO DE LOS PACIENTES CON LINFOMA DE HODGKIN LUEGO DEL TRASPLANTE AUTÓLOGO DE PROGENITORES HEMATOPOYÉTICOS
Hasta el diseño del ensayo AETHERA no se había contemplado de manera estructurada la posibilidad de consolidar los resultados del trasplante autólogo en los pacientes con riesgo elevado de recaída.

Anna Sureda Balari
Barcelona, España

     

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HEREDITARY HEMORRHAGIC TELANGIECTASIA
Hereditary hemorrhagic telangiectasia (HHT) is a rare autosomal dominant inherited disorder of the vascular system. It is usually asymptomatic but when symptomatic most common presentation is epistaxis. It can involve any organs of the body like lungs, skin, liver brain, GI mucosa etc. We are reporting a case of HHT presented to us with dyspnea and severe anemia. He had arteriovenous malformations of different visceral organs and telangiectasia of skin along with presence of similar history in first-degree relatives.

Kaushik Saha
Burdwan, In

  

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  VARIABILIDAD DE LA RESPUESTA PLAQUETARIA A LA ASPIRINA
La respuesta a la aspirina demostró una notoria variabilidad interevaluación, interindividual y temporal. Las evaluaciones repetidas que utilizan distintos ensayos son necesarias para diagnosticar de manera fiable la resistencia a la aspirina.

Sara Fairley
Wellington, Nueva Zelanda

           

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HYPOTHYROIDISM IN CLINICAL PRACTICE . CASES HOW TO APPROACH TO PATIENTS IN CLINIC
Hypothyroidism is the most common endocrine disease that was seen in the clinical practice especially for family physicians. Methods: This review article covered the important practical clinical issues for managing overt hypothyroidism, subclinical hypothyroidism and hypothyroidism during pregnancy. Conclusions: The clinical issues were addressed by clinical scenario followed by questions and stressed on the important clinical points

Faiza Qari
Jeddah, Sa

  

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