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La creciente cantidad de artículos con Acceso Abierto (Open
Access) amplía la oferta de lectura pero a su vez también, entre
tanta abundancia, complica al lector en su encuentro con los estudios
fundamentales. Para facilitarlo, profesionales biomédicos de SIIC
consultan diariamente una profusa cantidad de documentos que nutrirán
Textos completos autorizados (TCA).
Las citas de la sección TCA enlazan de manera legal, autorizada y
gratuita con los textos completos (full text) publicados en
los sitios oficiales de sus respectivas fuentes.
SIIC creó, produjo y opera con exclusividad el software TCA para la
interpretación de los diversos campos documentales que integran la
estructura de un estudio: especialidad, modalidad del estudio,
fuente, fechas de publicación y selección, definición de la fuente,
limitaciones de consulta, resumen en castellano, etc.
Si bien la mayoría de los textos seleccionados corresponden a
artículos originales, revisiones y guías, los lectores también
encontrarán comentarios, entrevistas, notas periodísticas, cartas a
autores u otros textos precursores de debates o aclaratorios.
Sociedad Iberoamericana de Información Científica (SIIC) selects
complete quality-full texts which have been recently published in
renowned sources worldwide and are indexed by SIIC Data
Bases.
The increasing number of Open Access articles widens the reading offer
but, also, such myriad complicates the readers search of fundamental
articles. To facilitate this, SIIC biomedical professionals daily
consult a profuse amount of documents that will feed
Authorized Full Texts (TCA, Spanish acronym).
The citations of the AFT section link legally, authorized and free of
charge with the full texts published in the official web sites of
their corresponding sources.
SIIC created, produced and handles the AFT software that deciphers
the various documentary fields that form part of the structure of a
study: specialty, study style, source, publication and selection
dates, source definition, query limitations, summary in Spanish,
etc.
While most of the selected texts belong to original articles,
reviews, and guidelines, readers will also find commentaries,
interviews, journalistic reports, letters to authors or other texts
that may lead to discussions or clarifications.
Extracto:
Although SDM is important
for most patients living with diabetes, the evidence from included studies
suggest that providers in diabetes practice do not universally express positive
views towards SDM. Because T2DM patients and their providers need to work
together to implement the SDM approach satisfactorily, there is a need to
encourage more providers to do so.
institución:(a) Diabetes Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. m_peimani@alumnus.tums.ac.ir. (b) Center for Aging in Diverse Communities, Institute for Health & Aging, University of California San Francisco, San Francisco, CA, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Clinical management of female patients with Fabry disease based on expert consensus.
Clinical management of female patients with Fabry disease based on expert consensus.
Fuente:Orphanet Journal of Rare Diseases
Extracto:
Despite current
recommendations, the experts agreed that early disease-specific treatment
initiation in high-risk females could improve clinical outcome.
institución:(a) Department of Nephrology, Hypertension and Rheumatology, and Interdisciplinary Fabry Centre Münster (IFAZ), University Hospital Münster, Münster, Germany. Eva.Brand@ukmuenster.de. (b) Internal Medicine D, Department of Nephrology, Hypertension and Rheumatology and Interdisciplinary Fabry Centre Münster (IFAZ), University Hospital Münster, Albert-Schweitzer-Campus 1, 48149, Münster, Germany. Eva.Brand@ukmuenster.de.
Conflicto:Declarations. Ethics approval and consent to participate: All procedures followed for the patient interviews were in accordance with the Helsinki Declaration 1975. Informed consent was obtained from all patients interviewed. Consent for publication: Not applicable. Competing interests: Eva Brand received research grants and speaker/consulting honoraria from Amicus Therapeutics, Chiesi, Sanofi, and Takeda. Aleš Linhart received speakers and consulting fees from...
m Amicus Therapeutics, Chiesi, Sanofi, and Takeda. Patrick Deegan received speaker/consulting honoraria from Amicus Therapeutics, Chiesi, Sanofi and Takeda, and research grants from Sanofi and Takeda. Ruxandra Jurcut received non-restrictive educational grants and speaker fees from Genesis Pharma (representing Amicus), Sanofi, and Takeda. Antonio Pisani received travel expenses and grants from Amicus, Sanofi, Chiesi-Protalix and Takeda-Shire. Roser Torra received speaker/consulting honoraria from Amicus Therapeutics, Chiesi, Sanofi Genzyme, and Takeda. Ulla Feldt-Rasmussen received unrestricted educational grants and speaker/consulting honoraria from Amicus Therapeutics, Chiesi, Freeline, Sanofi, and Takeda; Ulla Feldt-Rasmussen also received a research salary that was supported by a grant from Kirsten and Freddy Johansen’s Fund.
Change in pericardial fat volume in postmenopausal women with papillary thyroid cancer undergoing thyrotropin suppressive therapy.
Change in pericardial fat volume in postmenopausal women with papillary thyroid cancer undergoing thyrotropin suppressive therapy.
Fuente:Bmc Endocrine Disorders
Extracto:
Both skeletal muscle
and abdominal fat volumes did not change, whereas epicardial fat volume increased
over less than 2 years of observation under TSH suppressive therapy. Further
research is needed for the harmonization of benefits or losses with the optimal
TSH concentration in postmenopausal women.
institución:(a) Division of Endocrinology, Department of Internal Medicine, Pusan National University Hospital, Busan, Republic of Korea. (b) Biomedical Research Institute, Pusan National University Hospital, Busan, Republic of Korea.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Comprehensive Iranian guidelines for the diagnosis and management of maple syrup urine disease
Comprehensive Iranian guidelines for the diagnosis and management of maple syrup urine disease
Fuente:Orphanet Journal of Rare Diseases
Tipo de trabajo:Consenso
Extracto:
This article
considers pathogenesis, epidemiology, clinical manifestations, diagnosis,
treatment, and monitoring of MSUD patients with limited recourse.
Claves:BCKDHA, BCKDHB, Inherited metabolic disorder, Maple syrup urine disease
institución:(a) Liver Disease Research Center, Isfahan University of Medical Sciences, Isfahan, Iran. (b) Pediatric Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Partial rejuvenation of the spermatogonial stem cell niche after gender-affirming hormone therapy in trans women.
Partial rejuvenation of the spermatogonial stem cell niche after gender-affirming hormone therapy in trans women.
Fuente:Elife
Extracto:
These findings are important to further understand how estrogens and
testosterone suppression affect the testis environment, and in the case of
orchidectomized testes as medical waste material, their potential use in
research.
Autor/es:Delgouffe, Emily (a) Silva, Samuel Madureira (b)
institución:(a) Biology of the Testis (BITE) Laboratory, Genetics, Reproduction and Development (GRAD) Research Group, Vrije Universiteit Brussel, Brussels, Belgium. (b) Biology of the Testis (BITE) Laboratory, Genetics, Reproduction and Development (GRAD) Research Group, Vrije Universiteit Brussel, Brussels, Belgium.
institución:(a) Amrita Vishwa Vidyapeetham, Amrita College of Nursing, Amrita Institute of Medical Sciences and Research Centre, Kochi, India. (b) Amrita Vishwa Vidyapeetham, Obstetrics and Gynecology, Amrita Institute of Medical Sciences and Research Centre, Cochin, Kerala, India.
Conflicto:Competing interests: No, there are no competing interests.
A case study on using a large language model to analyze continuous glucose monitoring data.
A case study on using a large language model to analyze continuous glucose monitoring data.
Fuente:Scientific Reports
Extracto:
Our work serves as a preliminary study on
how generative language models can be integrated into diabetes care through data
summarization and, more broadly, the potential to leverage LLMs for streamlined
medical time series analysis.
Cita:Sci Rep 2025 Jan 7; 15 (1) : 1143.
Autor/es:Healey, Elizabeth (a) Tan, Amelia Li Min (b)
institución:(a) Program in Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA. ehealey@mit.edu. (b) Department of Biomedical Informatics, Harvard Medical School, Boston, MA, 02115, USA. ehealey@mit.edu.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Hsa_circ_0109623 regulates the progression of autoimmune liver disease through Hsa_miR_146b-3p/Sortilin 1-mediated activation of CD4+ T cells.
Hsa_circ_0109623 regulates the progression of autoimmune liver disease through Hsa_miR_146b-3p/Sortilin 1-mediated activation of CD4+ T cells.
Fuente:Hepatology Communications
Extracto:
The
hsa_circ_0109623/hsa-miR-146b-3p/SORT1 axis plays a crucial role in the
pathogenesis of AIH by regulating CD4+ T-cell activation and cytokine production.
These molecules may serve as potential biomarkers and therapeutic targets for
AIH. Further research is needed to validate these findings and explore their
clinical applications.
Cita:Hepatol Commun 2025 Jan 1; 9 (1)
Autor/es:Lv, Xinliang (a) Zhu, Li (b)
institución:(a) Department of Rheumatology, Inner Mongolia Autonomous Region Hospital of Traditional Chinese Medicine, Hohhot, P.R. China. (b) Department of Endocrinology, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, P.R. China.
Conflicto:The authors have no conflicts to report.
Vulnerable parafoveal microcirculation quadrant in patients with type 2 diabetes mellitus.
Vulnerable parafoveal microcirculation quadrant in patients with type 2 diabetes mellitus.
Fuente:Scientific Reports
Extracto:
OCTA-derived VD metrics
offer promise for early DR detection and underscore the importance of monitoring
vascular changes in DM patients.
Claves:Diabetic retinopathy, Optical coherence tomography angiography, Vessel density
Cita:Sci Rep 2025 Jan 7; 15 (1) : 1237.
Autor/es:Lin, Chen-Yu (a) Sheen, Yi-Jing (b)
institución:(a) Department of Ophthalmology, Taichung Veterans General Hospital, No.1650, Sec. 4, Taiwan Blvd., Xitun Dist., Taichung, Taiwan. cylinscholar@gmail.com. (b) Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Impact of bariatric surgery on liver fibrosis indices among type 2 diabetes patients in a national cohort.
Impact of bariatric surgery on liver fibrosis indices among type 2 diabetes patients in a national cohort.
Fuente:Scientific Reports
Extracto:
Bariatric
surgery significantly improves NFS and cause alterations in APRI and Fib-4 index
levels without increasing the risk of liver cirrhosis development among patients
with T2D and obesity.
Claves:Bariatric surgery, Liver fibrosis, Metabolic surgery, Obesity, Wight loss
institución:(a) Endocrinology and Metabolism Research Center (EMRC), School of Medicine, Vali-Asr Hospital, Imam Khomeini Hospital, Tehran, Iran. (b) Endocrinology and Metabolism Research Center (EMRC), School of Medicine, Vali-Asr Hospital, Imam Khomeini Hospital, Tehran, Iran.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Learnings from Implementation Strategies to Improve Lipid Management.
Learnings from Implementation Strategies to Improve Lipid Management.
Fuente:Current Cardiology Reports
Tipo de trabajo:Revisión
Extracto:
By doing so, ongoing implementation studies will help researchers better
understand the impact, sustainability and scalability of strategies, and where
barriers and facilitators to lipid management may exist in other contexts.
Autor/es:Lan, Nick S R (a) Chen, Ruofei Trophy (b)
institución:(a) Department of Cardiology, Fiona Stanley Hospital, Perth, WA, Australia. nick.lan@uwa.edu.au. (b) Medical School, The University of Western Australia, 35 Stirling Highway, Crawley, Perth, WA, 6009, Australia. nick.lan@uwa.edu.au.
Conflicto:Declarations. Conflict of Interest: NSRL has received research funding from Sanofi as part of a Clinical Fellowship in Endocrinology and Diabetes, education support from Amgen, AstraZeneca, Bayer, Boehringer Ingelheim, CSL Seqirus, Eli Lilly, Novartis and Pfizer, speaker honoraria from Amgen, AstraZeneca, Boehringer Ingelheim, Eli Lilly, Menarini, Novartis and Sanofi, and has participated in advisory boards for Eli Lilly. RTC has...
nothing to declare. SJN has received research support from AstraZeneca, Amgen, Anthera, CSL Behring, Cerenis, Cyclarity, Eli Lilly, Esperion, Resverlogix, New Amsterdam Pharma, Novartis, InfraReDx and Sanofi-Regeneron and is also a consultant for Amgen, Akcea, AstraZeneca, Boehringer Ingelheim, CSL Behring, Cyclarity, Daiichi Sankyo, Eli Lilly, Esperion, Kowa, Merck, Takeda, Pfizer, Sanofi- Regeneron, Vaxxinity, CSL Seqirus, and Novo Nordisk. GD reports paid lectures from AstraZeneca, Pfizer and Amgen and provides consultancy services and has equity interest in Artrya Ltd. GFW has received honoraria for advisory boards and research grants from Amgen, Arrowhead, Esperion, Gemphire, Kowa, Novartis, Pfizer, Sanofi, Novo Nordisk and Regeneron. AJN has received research support from AstraZeneca, Amgen, Eli Lilly, Novartis and is a consultant for Amgen, AstraZeneca, Boehringer Ingelheim, CSL Sequiris, Eli Lilly, GSK, Sanofi Pasteur and Novo Nordisk. Human and Animal Rights and Informed Consent: This article does not contain any studies with human or animal subjects performed by any of the authors.
Autor/es:Merzel Šabović, Eva Klara (a) Kraner Šumenjak, Tadeja (b)
institución:(a) Department of Dermatovenerology, University Medical Centre Ljubljana, Gradiškova ulica 10, Ljubljana, Slovenia. em2230@student.uni-lj.si. (b) Faculty of Medicine, University of Ljubljana, Vrazov trg 2, Ljubljana, Slovenia. em2230@student.uni-lj.si.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Comparison of the audit method and secondary data sources for assessing health-related characteristics of the built environment in a Brazilian city.
Comparison of the audit method and secondary data sources for assessing health-related characteristics of the built environment in a Brazilian city.
Fuente:Cadernos de Saude Publica
Extracto:
Hence, secondary data
should be used with caution to assess health-related characteristics of the built
environment in the poorest areas of Brazilian cities.
Cita:Cad Saude Publica 2024; 40 (11) : e00061124.
Autor/es:Cafruni, Cristina Borges (a) Garcez, Anderson (b)
institución:(a) Universidade Federal do Rio Grande do Sul, Porto Alegre, Brasil. (b) Programa de Pós-graduação em Ciências da Nutrição, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brasil.
The challenge of preventing gastric cancer in patients under surveillance for familial adenomatous polyposis.
The challenge of preventing gastric cancer in patients under surveillance for familial adenomatous polyposis.
Fuente:Familial Cancer
Extracto:
We aim to raise awareness on gastric cancer risk
in FAP patients and stress the urgent need of improved gastric surveillance
strategies with timely detection of gastric cancer precursors.
Autor/es:Bouchiba, Hicham (a) Aelvoet, Arthur S (b)
institución:(a) Department of Gastroenterology and Hepatology, Amsterdam UMC, University of Amsterdam, Amsterdam Gastroenterology Endocrinology Metabolism, Cancer Center Amsterdam, Amsterdam, The Netherlands. (b) Department of Gastroenterology and Hepatology, Amsterdam UMC, University of Amsterdam, Amsterdam Gastroenterology Endocrinology Metabolism, Cancer Center Amsterdam, Amsterdam, The Netherlands.
Conflicto:Declarations. Competing interests: Competing interests Hicham Bouchiba: nothing to disclose. Arthur S. Aelvoet: nothing to disclose. Lodewijk A. A. Brosens: nothing to disclose. Nicole C. T. van Grieken: nothing to disclose. Barbara A. J. Bastiaansen: speaker’s fee from Olympus, Tillots Pharma AG, Ovesco Endoscopy AG Evelien Dekker: Endoscopic equipment on loan of FujiFilm, and received a research grant from FujiFilm....
m. Honoraria for consultancy from Olympus, Fujifilm, Ambu, InterVenn, Norgine, and Exact Sciences. Speakers' fees from Olympus, GI Supply, Norgine, IPSEN/Mayoly, FujiFilm and Steris. Ethical approval: All procedures followed were in accordance with the ethical standards of the responsible committee and with the Helsinki Declaration.
Association between diet quality during pregnancy of mothers and that of 3-year-old offspring
Association between diet quality during pregnancy of mothers and that of 3-year-old offspring
Fuente:Journal of Nutritional Science
Tipo de trabajo:Estudio de cohortes
Extracto:
A
high diet quality score during pregnancy was positively associated with that of
offspring, suggesting the importance of nutritional education in pregnant women
to improve their diet quality.
Claves:Birth cohort, Diet quality, Japan, Pregnant women, Preschool children
Cita:J Nutr Sci 2024; 13 : e26.
Autor/es:Tada, Yuki (a) Ishitsuka, Kazue (b)
institución:(a) Department of Nutritional Science, Faculty of Applied Bioscience, Tokyo University of Agriculture, Tokyo, Japan. (b) Department of Social Medicine, National Center for Child Health and Development, Tokyo, Japan.
Nonlinear relationship between serum Klotho and chronic kidney disease in US adults with metabolic syndrome.
Nonlinear relationship between serum Klotho and chronic kidney disease in US adults with metabolic syndrome.
Fuente:Frontiers in Endocrinology
Extracto:
A nonlinear L-shaped
relationship exists between serum Klotho levels and risks of CKD among
middle-aged and older adults with MetS, with the lowest prevalence observed at
9.63 to 9.94 pg/mL Klotho concentrations. Our findings, if replicated, underscore
the need to estimate the optimal serum Klotho concentrations and the
consequential inverse relationship, thus implying the potential of Klotho as both
a serum biomarker and a possible preventive or therapeutic intervention.
institución:(a) National Clinical Research Center for Metabolic Diseases, Key Laboratory of Diabetes Immunology (Central South University), Ministry of Education, and Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, Changsha, China. (b) National Clinical Research Center for Metabolic Diseases, Key Laboratory of Diabetes Immunology (Central South University), Ministry of Education, and Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, Changsha, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Perfluorinated compounds linked to central precocious puberty in girls during COVID-19: an untargeted metabolomics study.
Perfluorinated compounds linked to central precocious puberty in girls during COVID-19: an untargeted metabolomics study.
Fuente:Frontiers in Endocrinology
Extracto:
Perfluorinated compounds may
promote CPP in girls by interfering with various pathways and affecting the
hypothalamic-pituitary-gonadal axis function. This study highlighted the need for
further research and public health measures to address environmental endocrine
disruptors.
institución:(a) Department of Pediatrics, Hainan Medical University School of Pediatrics, Hainan Women and Children's Medical Center, Haikou, Hainan, China. (b) Department of Pediatrics, Hainan Women and Children's Medical Center, Haikou, Hainan, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
How do immune cells shape type 1 diabetes? Insights from Mendelian randomization.
How do immune cells shape type 1 diabetes? Insights from Mendelian randomization.
Fuente:Frontiers in Endocrinology
Extracto:
The MR analysis demonstrated that seven
immune cell phenotypes were associated with an increased genetic susceptibility
to T1D. These findings provide a new direction for the pathogenesis of and the
drug development for T1D.
Claves:GWAS, Mendelian randomization, immune cell, phenotype, type 1 diabetes
institución:(a) School of Traditional Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, China. (b) Department of Endocrinology, The First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Serum Pentosidine in Relation to Obesity in Patients with Type 2 Diabetes and Healthy Controls.
Serum Pentosidine in Relation to Obesity in Patients with Type 2 Diabetes and Healthy Controls.
Fuente:Calcified Tissue International
Extracto:
Adjustment for
patient's weight is needed when evaluating serum PEN levels in patients with
T2DM.Clinical Trial Information: NCT02551315.
Claves:Bone turnover, Obesity, Pentosidine, Type 2 diabetes
Cita:Calcif Tissue Int 2025 Jan 7; 116 (1) : 25.
Autor/es:Baumann, Sandra (a) Sewing, Lilian (b)
institución:(a) Division of Endocrinology and Diabetes, Spital Emmental, Burgdorf, Switzerland. (b) Division of Endocrinology, Diabetes and Metabolism, University Hospital Basel, Aeschenvorstadt 57, 4051, Basel, Switzerland.
Conflicto:Declarations. Conflict of interest: Sandra Baumann, Lilian Sewing, Cyril Traechslin, Wilma Verhagen-Kamerbeek, Leticia Grize, Marius Kraenzlin, and Christian Meier have nothing to declare. Human and Animal Rights and Informed Consent: The study was conducted in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical...
l standards. Informed Consent NHANES is conducted by the Centers for Disease Control and Prevention (CDC) and the National Center for Health Statistics (NCHS). The NCHS Research Ethics Review Committee reviewed and approved the NHANES study protocol. All participants signed written informed consent.
The Metabolic Treatabolome and Inborn Errors of Metabolism Knowledgebase therapy tool: Do not miss the opportunity to treat!
The Metabolic Treatabolome and Inborn Errors of Metabolism Knowledgebase therapy tool: Do not miss the opportunity to treat!
Fuente:Journal of Inherited Metabolic Disease
Extracto:
IEMbase now provides up-to-date, comprehensive information on clinical and
biochemical symptoms and therapeutic options, empowering patients, families,
healthcare professionals, and researchers in improving patient outcomes.
Claves:ICIMD, IEMbase, IMD, Treatabolome, inborn error of metabolism, treatable IEM
Autor/es:den Hollander, Bibiche (a) Hoytema van Konijnenburg, Eva M M (b)
institución:(a) Department of Pediatrics, Emma Children's Hospital, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands. (b) Emma Center for Personalized Medicine, Amsterdam UMC, Amsterdam, The Netherlands.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The authors declare no other conflicts of interest.
