Textos Completos Autorizados

Endocrinología y Metabolismo
SIIC selecciona textos completos de calidad y de reciente publicación en fuentes prestigiosas del mundo indizadas por SIIC Data Bases, capturadas en las mismas colecciones o en diversas bases especializadas.
La creciente cantidad de artículos con Acceso Abierto (Open Access) amplía la oferta de lectura pero a su vez también, entre tanta abundancia, complica al lector en su encuentro con los estudios fundamentales. Para facilitarlo, profesionales biomédicos de SIIC consultan diariamente una profusa cantidad de documentos que nutrirán Textos completos autorizados (TCA).

Las citas de la sección TCA enlazan de manera legal, autorizada y gratuita con los textos completos (full text) publicados en los sitios oficiales de sus respectivas fuentes.

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Si bien la mayoría de los textos seleccionados corresponden a artículos originales, revisiones y guías, los lectores también encontrarán comentarios, entrevistas, notas periodísticas, cartas a autores u otros textos precursores de debates o aclaratorios.

Con una o todas las palabras
(escribir en inglés)
 
Ej.1: Adipokines Ej.2: Adipokines or Musculoskeletal
Con la frase exacta
(inglés)

Ej.3: Adipokines and Cardiovascular Systems
Con todas de las palabras
(inglés)

Ej.4: Adipokines and Cardiovascular and Systems
Sin las palabras
(inglés)

Ej.5: not Cardiovascular Systems
Diabetes & metabolism journal
Selección SIIC: 24 Enero, 2025
Diabetes & metabolism journal

Diabetes Fact Sheets in Korea 2024.

Diabetes Fact Sheets in Korea 2024.

Fuente:Diabetes & Metabolism Journal

Extracto: Diabetes mellitus remains highly prevalent among Korean adults, with significant gaps in integrated glycemic, blood pressure, and lipid control. Older adults with diabetes show higher awareness and treatment rates but limited integrated management outcomes. Young adults with diabetes bear a significant burden of obesity and comorbidities, alongside low awareness and treatment rates. Therefore, early intervention programs, education, and strategies tailored to younger populations are urgently required.

Claves:Aged, Comorbidity, Diabetes mellitus, Prevalence, Republic of Korea, Young adult

Cita:Diabetes Metab J 2025 Jan; 49 (1) : 24-33.

Autor/es:Park, Se Eun (a)
Ko, Seung-Hyun (b)

institución:(a) Division of Endocrinology and Metabolism, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
(b) Division of Endocrinology and Metabolism, Department of Internal Medicine, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Corea del Sur

Sitio web:http://dx.doi.org/10.4093/dmj.2024.0818

Endokrynologia Polska
Selección SIIC: 24 Enero, 2025
Endokrynologia Polska

Novel radiopharmaceuticals in endocrinology

Novel radiopharmaceuticals in endocrinology

Fuente:Endokrynologia Polska

Tipo de trabajo:Revisión

Extracto: By providing a comprehensive overview of the evolving landscape of radiopharmaceuticals in endocrinology, this article aims to contribute to the collective knowledge base and foster a deeper understanding of the potential benefits and implications of these innovative technologies for both clinicians and researchers in the field of endocrine health.

Claves:NET, nuclear endocrinology, nuclear imaging, theranostics

Cita:Endokrynol Pol 2024; 75 (6) : 617-629.

Autor/es:Pocięgiel, Mateusz (a)
Saniewski, Tomasz (b)

institución:(a) Clinical Department of Internal Medicine, Endocrinology, Diabetology, and Nephrology, Czerniakowski Hospital, Warsaw, Poland. mateusz.pociegiel@op.pl.
(b) Clinical Department of Internal Medicine, Endocrinology, Diabetology, and Nephrology, Czerniakowski Hospital, Warsaw, Poland.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Polonia

Sitio web:http://dx.doi.org/10.5603/ep.99756

BMJ open
Selección SIIC: 24 Enero, 2025
BMJ open

Barriers and facilitators to the implementation of the Assessment of Burden of Chronic Conditions tool in Dutch primary care: a context analysis.

Barriers and facilitators to the implementation of the Assessment of Burden of Chronic Conditions tool in Dutch primary care: a context analysis.

Fuente:Bmj Open

Tipo de trabajo:Guía

Extracto: This study provides insight in the barriers and facilitators to the implementation of an intervention in the patient-HCP conversation. Barriers were present in complexity, available resources, patient needs and resources, and external policies and incentives while facilitators were present in knowledge and beliefs, implementation climate and culture. These barriers and facilitators provide opportunities for the selection and tailoring of implementation strategies for the ABCC tool.

Claves:Asthma, Chronic Disease, DIABETES & ENDOCRINOLOGY, Implementation Science, Primary Care, Pulmonary Disease, Chronic Obstructive

Cita:BMJ Open 2025 Jan 20; 15 (1) : e087197.

Autor/es:Claessens, Danny (a)
Boudewijns, Esther A (b)

institución:(a) Department of Family Medicine, Maastricht University, Maastricht, Netherlands danny.claessens@maastrichtuniversity.nl.
(b) Department of Family Medicine, Maastricht University, Maastricht, Netherlands.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjopen-2024-087197

Selección SIIC: 24 Enero, 2025

What are the perceptions and experiences of adults using mobile applications for self-management in diabetes? A systematic review.

What are the perceptions and experiences of adults using mobile applications for self-management in diabetes? A systematic review.

Fuente:Bmj Open

Tipo de trabajo:Revisión sistemática

Extracto: The review supports the favourable view of mobile applications as promising tools in helping patients with diabetes to self-manage. However, the challenges on the ease of use and non-customised features of the apps potentially hinder patients' long-term engagement.

Claves:Cell Phone, DIABETES & ENDOCRINOLOGY, Patients, Review, Self-Management, eHealth

Cita:BMJ Open 2025 Jan 20; 15 (1) : e086671.

Autor/es:Patail, Kalthum (a)
Pai, Hui Hsuan (b)

institución:(a) Primary Care and Public Health, Imperial College London, London, UK meditalents@gmail.com.
(b) Imperial College London, London, UK.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1136/bmjopen-2024-086671

BMC pregnancy and childbirth
Selección SIIC: 24 Enero, 2025
BMC pregnancy and childbirth

International expert consensus on micronutrient supplement use during the early life course.

International expert consensus on micronutrient supplement use during the early life course.

Fuente:Bmc Pregnancy and Childbirth

Tipo de trabajo:Consenso

Extracto: The findings revealed robust consensus on various aspects of maternal nutrition, including the need for education, the lack of consistency in current guidelines on supplement use, the importance of supplement use across specific phases of pregnancy and the at-risk groups requiring tailored approaches.

Claves:Guidelines, Lactation, Maternal diet, Preconception, Pregnancy, Trace-elements, Vitamins

Cita:BMC Pregnancy Childbirth 2025 Jan 20; 25 (1) : 44.

Autor/es:Cetin, Irene (a)
Devlieger, Roland (b)

institución:(a) Department of Women, Mother and Neonate, "Vittore Buzzi" Children's Hospital, University of Milan, Milan, Italy.
(b) Department of BioMedical and Clinical Sciences, University of Milan and Fondazione IRCCS CA' GRANDA, Ospedale Maggiore Policlinico, Milan, Italy.

Conflicto:Declarations. Ethics approval and consent to participate: The study was reviewed by Pearl Institutional Review Board (2023-0047, https://www.pearlirb.com/) and received a Category 2 exemption from full review, in accordance with the US Department of Health and Human Services and Code of Federal Regulations (CFR; 45 CFR 46.104(d)(2)). Participants gave informed consent to participate as part of the survey and could... masnoticias.gif

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12884-024-07123-5

Selección SIIC: 24 Enero, 2025

Physical behaviours during pregnancy may alter the association of maternal insulin sensitivity with neonatal adiposity: a prospective pre-birth cohort of mother-child pairs.

Physical behaviours during pregnancy may alter the association of maternal insulin sensitivity with neonatal adiposity: a prospective pre-birth cohort of mother-child pairs.

Fuente:Bmc Pregnancy and Childbirth

Extracto: The association between lower insulin sensitivity and higher neonatal adiposity was attenuated in women with higher physical activity levels in the second trimester, independent of maternal body mass index.

Claves:Birthweight, Insulin resistance, Insulin sensitivity, Neonatal adiposity, Physical activity, Pregnancy, Sedentary behaviour, Skinfold thickness, Sleep

Cita:BMC Pregnancy Childbirth 2025 Jan 20; 25 (1) : 41.

Autor/es:Satkunanathan, Piraveena (a)
Allard, Catherine (b)

institución:(a) Division of Experimental Medicine, McGill University, Montreal, Québec, Canada.
(b) Centre for Clinical Epidemiology, Lady Davis Research Institute, Montreal, Québec, Canada.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12884-025-07148-4

BMC medical informatics and decision making
Selección SIIC: 24 Enero, 2025
BMC medical informatics and decision making

Towards a decision support system for post bariatric hypoglycaemia: development of forecasting algorithms in unrestricted daily-life conditions.

Towards a decision support system for post bariatric hypoglycaemia: development of forecasting algorithms in unrestricted daily-life conditions.

Fuente:Bmc Medical Informatics and Decision Making

Extracto: Real-time forecasting of PBH events using CGM data as a single input imposes high demands on various types of prediction algorithms, with CGM data noise and rapid postprandial glucose dynamics representing the key challenges. In this study, the run-to-run rAR yielded most satisfactory results with accurate PBH event predictive capacity and few false alarms, thereby indicating potential for the development of DSS for people with PBH.

Claves:Continuous glucose monitoring, Data-driven forecasting models, Post bariatric hypoglycaemia

Cita:BMC Med Inform Decis Mak 2025 Jan 20; 25 (1) : 33.

Autor/es:Prendin, Francesco (a)
Streicher, Olivia (b)

institución:(a) Department of Information Engineering (DEI), University of Padova, Via G. Gradenigo 6/B, Padua, 35131, Italy.
(b) Department of Diabetes, Endocrinology, Nutritional Medicine and Metabolism, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12911-025-02856-5

Gynecological endocrinology the official journal of the International Society of Gynecological Endocrinology

Selección SIIC: 24 Enero, 2025

Gynecological endocrinology the official journal of the International Society of Gynecological Endocrinology

Novel serum biomarkers for early diagnosis of gestational diabetes mellitus-a review.

Novel serum biomarkers for early diagnosis of gestational diabetes mellitus-a review.

Fuente:Gynecological Endocrinology The Official Journal of The International Society of Gynecological Endocrinology

Extracto: We believe these biomarkers may allow for the detection of GDM in the early stages of pregnancy, enabling timely proper treatment and potentially preventing complications for both the mother and the fetus.

Claves:GDM, Gestational diabetes mellitus, biomarkers, maternal serum, pregnancy complications

Cita:Gynecol Endocrinol 2025 Dec; 41 (1) : 2455472.

Autor/es:Kunicki, Michał (a)
Rzewuska, Natalia (b)

institución:(a) Department of Gynecological Endocrinology, Medical University of Warsaw, Warsaw, Poland.
(b) INVICTA Fertility and Reproductive Center, Warsaw, Poland.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1080/09513590.2025.2455472

Swiss medical weekly
Selección SIIC: 24 Enero, 2025
Swiss medical weekly

Self-reported perceptions of adults with diabetes regarding their care and health in the time of COVID-19 pandemic in a Swiss region: a cross-sectional study.

Self-reported perceptions of adults with diabetes regarding their care and health in the time of COVID-19 pandemic in a Swiss region: a cross-sectional study.

Fuente:Swiss Medical Weekly

Extracto: Diabetes self-management, glucose control, and access to diabetes care were not severely affected for the CoDiab-VD cohort during the COVID-19 pandemic. Despite some reported postponements in care and increased difficulty in physical activity management, the majority maintained their diabetes management practices with minimal impact on glucose control. Overall, psychosocial worry about the pandemic was relatively low, highlighting the resilience of individuals in managing their diabetes despite challenging circumstances. CLINICALTRIALS: gov number: NCT01902043.

Cita:Swiss Med Wkly 2024 Dec 5; 154 : 3578.

Autor/es:Kosinski, Christophe (a)
Zuercher, Emilie (b)

institución:(a) Service of Endocrinology, Diabetes and Metabolism, Department of Medicine, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland.
(b) Service of Endocrinology, Diabetes, Nutrition and Therapeutic Patient Education, Geneva University Hospitals, Geneva, Switzerland.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.57187/s.3578

Journal of medical Internet research
Selección SIIC: 24 Enero, 2025
Journal of medical Internet research

What's Going On With Me and How Can I Better Manage My Health? The Potential of GPT-4 to Transform Discharge Letters Into Patient-Centered Letters to Enhance Patient Safety: Prospective, Exploratory Study.

What's Going On With Me and How Can I Better Manage My Health? The Potential of GPT-4 to Transform Discharge Letters Into Patient-Centered Letters to Enhance Patient Safety: Prospective, Exploratory Study.

Fuente:Journal of Medical Internet Research

Extracto: Our study demonstrates that GPT-4 has the potential to transform discharge letters into more patient-centered communication. While the readability and patient centricity of the transformed letters are well-established, they do not fully address all patient safety-relevant information, resulting in the omission of key aspects. Further optimization of prompt engineering may help address this issue and improve the completeness of the transformation.

Claves:GPT-4, artificial intelligence, health care communication, patient education, patient letters, patient safety

Cita:J Med Internet Res 2025 Jan 21; 27 : e67143.

Autor/es:Eisinger, Felix (a)
Holderried, Friederike (b)

institución:(a) Department of Diabetology, Endocrinology, Nephrology, University of Tübingen, Tübingen, Germany.
(b) Tübingen Institute for Medical Education, University of Tübingen, Tübingen, Germany.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Canadá

Sitio web:http://dx.doi.org/10.2196/67143

Scientific reports
Selección SIIC: 24 Enero, 2025
Scientific reports

Machine learning based prediction models for the prognosis of COVID-19 patients with DKA.

Machine learning based prediction models for the prognosis of COVID-19 patients with DKA.

Fuente:Scientific Reports

Extracto: This study developed a machine learning-based predictive model for the progression to severe disease or death in COVID-19 patients with DKA, which can serve as a valuable tool to guide clinical treatment decisions.

Claves:COVID-19, Diabetes, Ketoacidosis, Machine learning, Prediction

Cita:Sci Rep 2025 Jan 21; 15 (1) : 2633.

Autor/es:Xiang, Zhongyuan (a)
Hu, Jingyi (b)

institución:(a) Department of Laboratory Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China. xiangzhongyuan@csu.edu.cn.
(b) Department of Laboratory Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China. hujingyi0066@csu.edu.cn.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1038/s41598-025-85357-9

BMC endocrine disorders
Selección SIIC: 24 Enero, 2025
BMC endocrine disorders

A beneficial levels of 25-hydroxyvitamin D for a decrease in thyrotropin receptor antibody (TRAB) in patients with Graves' disease: a real-world study.

A beneficial levels of 25-hydroxyvitamin D for a decrease in thyrotropin receptor antibody (TRAB) in patients with Graves' disease: a real-world study.

Fuente:Bmc Endocrine Disorders

Extracto: Newly diagnosed GD patients with appropriate baseline 25-hydroxyvitamin D levels (20-29 ng/mL) are beneficial for the reduction of TRAB during antithyroid therapy.

Claves:Graves’disease, 25-hydroxyvitamin D, Negative conversion rate, TRAB remission rate, Thyroid function

Cita:BMC Endocr Disord 2025 Jan 21; 25 (1) : 14.

Autor/es:Chen, Xide (a)
Zhang, Yongze (b)

institución:(a) Department of Endocrinology, The First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, China.
(b) Department of Endocrinology, Binhai Campus of the First Affiliated Hospital, National Regional Medical Center, Fujian Medical University, Fuzhou, 350212, China.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12902-024-01823-x

Frontiers in public health
Selección SIIC: 24 Enero, 2025
Frontiers in public health

Higher triglyceride-glucose index and triglyceride glucose-body mass index protect against sarcopenia in Chinese middle-aged and older non-diabetic women: a cross-sectional study.

Higher triglyceride-glucose index and triglyceride glucose-body mass index protect against sarcopenia in Chinese middle-aged and older non-diabetic women: a cross-sectional study.

Fuente:Frontiers in Public Health

Extracto: Higher TyG index and TyG-BMI index protected against sarcopenia in non-diabetic middle-aged and older females. Moreover, the TyG-BMI index was a reliable and cost-efficient biomarker to predict sarcopenia.

Claves:insulin resistance, middle-aged and older non-diabetic women, sarcopenia, triglyceride glucose-body mass index, triglyceride-glucose index

Cita:Front Public Health 2024; 12 : 1475330.

Autor/es:Li, Min (a)
Liu, Ying (b)

institución:(a) Department of Endocrinology, Hebei Medical University Third Hospital, Shijiazhuang, Hebei, China.
(b) Department of Radiology, Hebei Medical University Third Hospital, Shijiazhuang, Hebei, China.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fpubh.2024.1475330

Frontiers in endocrinology
Selección SIIC: 24 Enero, 2025
Frontiers in endocrinology

Family planning and preimplantation testing: family experiences in congenital adrenal hyperplasia.

Family planning and preimplantation testing: family experiences in congenital adrenal hyperplasia.

Fuente:Frontiers in Endocrinology

Extracto: This study highlights the complex and dynamic nature of fertility decision-making, and the importance of HCP empathy and open-mindedness. Education of HCP and encouraging peer support may improve the CAH and fertility journey for families.

Claves:congenital adrenal hyperplasia, decision-making, family planning, preimplantation diagnosis, prenatal diagnosis

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1482902.

Autor/es:Sandy, Jessica L (a)
Betts, Grant (b)

institución:(a) Department of Endocrinology, Sydney Children's Hospital, Randwick, NSW, Australia.
(b) Children's Hospital Westmead Clinical School, University of Sydney, Sydney, NSW, Australia.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1482902

Selección SIIC: 24 Enero, 2025

Increased risk of type 2 diabetes after traumatic amputation

Increased risk of type 2 diabetes after traumatic amputation

Fuente:Frontiers in Endocrinology

Tipo de trabajo:Estudio de cohortes

Extracto: Individuals with amputation were at significantly greater risk for T2DM than the general population, particularly those with severe disability and proximal amputation. Innovative strategies that improve and support the long-term T2DM risk for severely injured individuals with proximal amputation are warranted.

Claves:amputation, disability, proximal amputation, trauma, type 2 diabetes

Cita:Front Endocrinol (Lausanne) 2024; 15 : 1437860.

Autor/es:Yoo, Jung Eun (a)
Lee, Dagyeong (b)

institución:(a) Department of Family Medicine, Healthcare System Gangnam Center, Seoul National University Hospital, Seoul, Republic of Korea.
(b) Department of Family Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.

Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Suiza

Sitio web:http://dx.doi.org/10.3389/fendo.2024.1437860

Annals of medicine
Selección SIIC: 24 Enero, 2025
Annals of medicine

Age-specific abnormal glucose metabolism in HIV-positive people on antiviral therapy in China: a multicenter case-control study.

Age-specific abnormal glucose metabolism in HIV-positive people on antiviral therapy in China: a multicenter case-control study.

Fuente:Annals of Medicine

Extracto: HIV infection is associated with early onset and high prevalence of IR and IFG. Longer duration of HIV infection and cART usage increased the occurrence of DM. These findings contribute to a better understanding of age-specific AGM and the modified glucose monitor strategies in PLWH.

Claves:AIDS, HIV, abnormal glucose metabolism, diabetes mellitus, impaired fasting glucose, insulin resistance

Cita:Ann Med 2025 Dec; 57 (1) : 2427910.

Autor/es:Xu, Lijun (a)
Chen, Mengsha (b)

institución:(a) National Clinical Research Center for Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
(b) The State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Conflicto:No potential competing interest was reported by the authors.

Formato:Informe impreso

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1080/07853890.2024.2427910

PloS one
Selección SIIC: 24 Enero, 2025
PloS one

Female Brain and Endocrinological Research-Veteran (FemBER-Vet) study: A study protocol for identifying endocrinological, lifestyle and psychosocial determinants of brain health outcomes in female veterans for future intervention success.

Female Brain and Endocrinological Research-Veteran (FemBER-Vet) study: A study protocol for identifying endocrinological, lifestyle and psychosocial determinants of brain health outcomes in female veterans for future intervention success.

Fuente:Plos One

Extracto: Ultimately, it will provide evidence to support the development of tailored interventions for an emerging health priority that currently lacks sufficient evidence for screening and therapeutic intervention.

Cita:PLoS One 2025; 20 (1) : e0306149.

Autor/es:Watermeyer, Tamlyn (a)
Atkinson, Elliott (b)

institución:(a) Faculty of Health & Life Sciences, Northumbria University, Newcastle, United Kingdom.
(b) Edinburgh Dementia Prevention, University of Edinburgh, Edinburgh, United Kingdom.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0306149

Selección SIIC: 24 Enero, 2025

An anonymized, de-identified registry study protocol to determine the effectiveness and safety of weight loss with enavogliflozin in patients with type 2 diabetes mellitus.

An anonymized, de-identified registry study protocol to determine the effectiveness and safety of weight loss with enavogliflozin in patients with type 2 diabetes mellitus.

Fuente:Plos One

Extracto: This study design enables us to evaluate the effectiveness and safety of enavogliflozin for weight loss in a real-world setting while exploring its potential positive effects on cardiac function and metabolic risk factors in overweight or obese patients with T2D.

Cita:PLoS One 2025; 20 (1) : e0315603.

Autor/es:Sang, Hyunji (a)
Kim, Sunyoung (b)

institución:(a) Department of Endocrinology and Metabolism, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, South Korea.
(b) Center for Digital Health, Medical Science Research Institute, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, South Korea.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:EE.UU.

Sitio web:http://dx.doi.org/10.1371/journal.pone.0315603

Critical care (London, England)
Selección SIIC: 24 Enero, 2025
Critical care (London, England)

Cardiovascular effects of lactate in healthy adults.

Cardiovascular effects of lactate in healthy adults.

Fuente:Critical Care (london, England)

Tipo de trabajo:Estudio clínico

Extracto: In healthy participants, LAC infusion enhanced cardiac function, evidenced by increases in CO, stroke volume, and left ventricular ejection fraction compared with SAL. Indicators of contractility improved, afterload decreased, and preload remained stable. Therefore, LAC infusion may be an advantageous resuscitation fluid, particularly in patients with cardiac dysfunction. CLINICAL TRIAL REGISTRATIONS: https://clinicaltrials.gov/ct2/show/NCT04710875 . Registered 1 December 2020.

Claves:Afterload, Cardiac output, Echocardiography, Lactate, Left ventricular ejection fraction, Preload

Cita:Crit Care 2025 Jan 17; 29 (1) : 30.

Autor/es:Berg-Hansen, Kristoffer (a)
Gopalasingam, Nigopan (b)

institución:(a) Department of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200, Aarhus N, Denmark. krisbe@rm.dk.
(b) Department of Clinical Medicine, Faculty of Health, Aarhus University, Aarhus, Denmark. krisbe@rm.dk.

Conflicto:Competing interests: Roni Nielsen has collaboration with the pharceutical companies Imbria, Medtrace, Resother as an investigation and has received lectural fee from Astrazeneca. Roni Nielsen is a patentholder of 20205938.2 A Lactate/Ketone Body ester, 5-11-2020. Henrik Wiggers has been the principal or a sub-investigator in studies involving the following pharmaceutical companies: MSD, Bayer, Daiichi-Sankyo, Novartis, Novo Nordisk, Sanofi-Aventis, and Pfizer.

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s13054-025-05259-0

Cardiovascular diabetology
Selección SIIC: 24 Enero, 2025
Cardiovascular diabetology

Longitudinal association between DNA methylation and type 2 diabetes: findings from the KORA F4/FF4 study.

Longitudinal association between DNA methylation and type 2 diabetes: findings from the KORA F4/FF4 study.

Fuente:Cardiovascular Diabetology

Extracto: Our study identified novel differentially methylated loci linked to T2D as well as to changes in diabetes status through a longitudinal approach. We report CpG sites with different rates of annual methylation change and demonstrate that DNA methylation associated with T2D is linked to following transcriptional differences. These findings provide new insights into the molecular mechanisms of diabetes development.

Claves:DNA methylation, Diabetes progression, Gene expression, Glycemic traits, Type 2 diabetes

Cita:Cardiovasc Diabetol 2025 Jan 18; 24 (1) : 19.

Autor/es:Lai, Liye (a)
Juntilla, Dave Laurence (b)

institución:(a) Research Unit Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Neuherberg, Germany. liye.lai@helmholtz-munich.de.
(b) Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Neuherberg, Germany. liye.lai@helmholtz-munich.de.

Conflicto:Los autores declaran no tener conflictos de interés con la investigación

Formato:Informe virtual

Idioma:Inglés

País de fuente:Reino Unido

Sitio web:http://dx.doi.org/10.1186/s12933-024-02558-8

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