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Association between adolescent obesity and early adulthood healthcare utilization-a two-cohort prospective study.
Association between adolescent obesity and early adulthood healthcare utilization-a two-cohort prospective study.
Fuente:Bmc Medicine
Extracto:
Analyses of real-world data cohorts from Norway and Sweden
reveal that adolescent obesity is associated with increased healthcare
utilization and costs in young adulthood, exceeding previous estimates. A
distinct sex difference was evident, with females incurring higher costs compared
to males.
Claves:Adolescent obesity, Health economics, Healthcare Costs, Healthcare utilization, Real-world data
Cita:BMC Med 2025 Jan 21; 23 (1) : 33.
Autor/es:Hagman, Emilia (a) Halsteinli, Vidar (b)
institución:(a) Department of Clinical Science, Intervention, and Technology, Karolinska Institutet, Huddinge, Sweden. emilia.hagman@ki.se. (b) Department of Surgery, Obesity Research Centre, St. Olavs Hospital Trondheim University Hospital, Trondheim, Norway.
Conflicto:Declarations. Ethics approval and consent to participate: An opt-out approval was required from the patient/guardian to record data in the Swedish Childhood Obesity Treatment Register. The regional Ethics Committee in Stockholm, Sweden, approved the study (No. No. 2016/922–31/1, 2020–02707). For the HUNT cohort all participants consented to the use of their data and the present study was approved by the...
the Regional Committee of Ethics in Medical Research (2016/537). Consent for publication: Not applicable. Competing interests: EH reports commissioned research for Novo Nordisk (2023), but not for the current study; honoraria for lectures for Novo Nordisk; a leadership or fiduciary role on scientific/medical committee: Member of the steering committee for the Swedish Childhood Obesity Treatment Register. CM reports consulting fees from Novo Nordisk,Rhythm, Oriflame Wellness, DeFaire Medical, and Evira AB; honoraria for lectures from Novo Nordisk, Oriflame Wellness, and AstraZeneca; payment for expert testimony from Novo Nordic Foundation and Rhythm; leadership or fiduciary role on scientific/medical committee: board member of European Society for Paediatric Endocrinology (ESPE) Obesity working group, board member of the Swedish Pediatric Obesity Society, and Register holder for the Swedish Childhood Obesity Treatment Register. RRP, VH, CHE, MWB and RAØ declare no competing interests.
Developing a rapid screening tool for high-risk ICU patients of sepsis: integrating electronic medical records with machine learning methods for mortality prediction in hospitalized patients-model establishment, internal and external validation, and visualization.
Developing a rapid screening tool for high-risk ICU patients of sepsis: integrating electronic medical records with machine learning methods for mortality prediction in hospitalized patients-model establishment, internal and external validation, and visualization.
Fuente:Journal of Translational Medicine
Extracto:
The application of machine learning-based
prediction models for sepsis could significantly improve patient outcomes through
early detection and timely intervention in the critical first 24 h of ICU
admission, supporting clinical decision-making.
institución:(a) Department of Critical Care Medicine, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital South Branch, Fujian Provincial Hospital, Fuzhou University Affiliated Provincial Hospital, Fuzhou, 350001, People's Republic of China. (b) Department of Critical Care Medicine, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital South Branch, Fujian Provincial Hospital, Fuzhou University Affiliated Provincial Hospital, Fuzhou, 350001, People's Republic of China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Association of childhood maltreatment and adverse lifetime experiences with post-injury psychopathology: evidence from the China Severe Trauma Cohort.
Association of childhood maltreatment and adverse lifetime experiences with post-injury psychopathology: evidence from the China Severe Trauma Cohort.
Fuente:Bmc Medicine
Tipo de trabajo:Estudio de cohortes
Extracto:
Both childhood
maltreatment and adverse lifetime experiences were associated with post-injury
psychopathology, irrespective of genetic susceptibility. Such findings highlight
the importance of close surveillance and timely psychological interventions for
injury patients with adverse life experiences.
Claves:Adverse life experience, Cohort study, Genetic susceptibility, Physical trauma, Psychopathology
Cita:BMC Med 2025 Jan 21; 23 (1) : 29.
Autor/es:Wen, Shu (a) Zeng, Yu (b)
institución:(a) Trauma Medical Center, Department of Orthopedics Surgery and Biomedical Big Data Center, West China Hospital, Sichuan University, Chengdu, China. (b) Department of Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Oncological Endocrinology Unit, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Regina Elena National Cancer Institute, Rome, Italy. (b) Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
Conflicto:AI discloses principal investigator role in sponsored trials and consultancies for Recordati, Corcept, HRA pharma, Neurocrine. GP discloses consultancies for Bayer. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
A real-world analysis of 1,823 hospitalized osteoporotic fractures in Northeast China.
A real-world analysis of 1,823 hospitalized osteoporotic fractures in Northeast China.
Fuente:Frontiers in Endocrinology
Extracto:
Hip fractures, especially femoral neck fractures,
accounted for the majority of osteoporotic fractures in a tertiary public
hospital in Northeast China. Common comorbidities in these fracture patients were
hyperlipemia and hypertension. There was a very low rate of AM use among these
patients.
Claves:aged people, case series, epidemiology, osteoporotic fractures, real-world analysis
institución:(a) Department of Endocrinology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, China. (b) Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun, Jilin, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The handling editor RB declared a past co-authorship/collaboration with the author(s) WL.
Evaluation of adrenal tumors and analysis of the metabolic profile of patients with incidentaloma.
Evaluation of adrenal tumors and analysis of the metabolic profile of patients with incidentaloma.
Fuente:Revista Do Colegio Brasileiro de Cirurgioes
Extracto:
The sample of patients with
adrenal tumors and incidentaloma at HUGG presented a prevalence of metabolic
complications similar to that found in the literature.
Cita:Rev Col Bras Cir 2025; 51 : e20243685.
Autor/es:Montalvão, Pedro Victor Gonçalves (a) Mangueira, Iuri Moura (b)
institución:(a) - Universidade Federal do Estado do Rio de Janeiro, Medicina - Rio de Janeiro - RJ - Brasil. (b) - Universidade Estadual do Rio de Janeiro, Serviço de Clínica Médica - Rio de Janeiro - RJ - Brasil.
Demographic and Clinical Characteristics of Patients With Charcot Neuro-Osteoarthropathy in People With Diabetes Mellitus in Six Countries: A Multicenter Observational Study From 1996 to 2022.
Demographic and Clinical Characteristics of Patients With Charcot Neuro-Osteoarthropathy in People With Diabetes Mellitus in Six Countries: A Multicenter Observational Study From 1996 to 2022.
Fuente:Journal of Diabetes Research
Extracto:
People with T1DM, compared to those with T2DM, are
affected at a younger age, have longer diabetes duration, and have more often
microvascular complications.
Claves:Charcot joint, arthropathy neurogenic, diabetes mellitus Type 1, diabetes mellitus Type 2
Cita:J Diabetes Res 2025; 2025 : 4275741.
Autor/es:Jude, E B (a) Siafarikas, C (b)
institución:(a) Department of Diabetes and Endocrinology, Tameside and Glossop Integrated Care NHS Foundation Trust, Ashton Under Lyne and University of Manchester and Manchester Metropolitan University, Manchester, UK. (b) First Department of Propaedeutic Internal Medicine, Medical School, National and Kapodistrian University of Athens, Laiko General Hospital, Athens, Greece.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Evaluating the quality of Spanish-language information for patients with type 2 diabetes on YouTube and Facebook.
Evaluating the quality of Spanish-language information for patients with type 2 diabetes on YouTube and Facebook.
Fuente:Health Informatics Journal
Extracto:
Conclusion: Our results suggest that videos about T2D in Spanish on social media
such as YouTube and Facebook have good reliability and quality, with greater
exhaustiveness in content in Facebook videos and greater reliability for videos
from government or news organizations.
Claves:information sources, internet, social media, type 2 diabetes
Autor/es:Soto-Chávez, María Juliana (a) Díaz-Brochero, Candida (b)
institución:(a) Department of Internal Medicine, Pontificia Universidad Javeriana, Bogotá, Colombia. RINGGOLD: 27964 (b) Department of Internal Medicine, Pontificia Universidad Javeriana, Bogotá, Colombia; Department of Internal Medicine, Hospital Universitario San Ignacio, Bogotá, Colombia. RINGGOLD: 27964. RINGGOLD: 173049
Conflicto:Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Experiences and opinions of adults with type 1 diabetes on the android-based open-source closed-loop system in China: a qualitative study.
Experiences and opinions of adults with type 1 diabetes on the android-based open-source closed-loop system in China: a qualitative study.
Fuente:Bmj Open
Tipo de trabajo:Estudio clínico
Extracto:
Adults with T1D had generally positive experiences with
AAPS. The future focus of AAPS research and development should be on optimising
glycaemic management, improving device experience and reducing costs. TRIAL
REGISTRATION NUMBER: NCT05726461; Pre-results.
Claves:diabetes & endocrinology, digital technology, patient satisfaction, qualitative research
Cita:BMJ Open 2025 Jan 15; 15 (1) : e094333.
Autor/es:Huang, Qingying (a) Ni, Ying (b)
institución:(a) Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-sen University, Guangdong Provincial Key Laboratory of Diabetology, Guangzhou, Guangdong, China. (b) Department of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-sen University, Guangdong Provincial Key Laboratory of Diabetology, Guangzhou, Guangdong, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Factors associated with weight loss response to GLP-1 analogues for obesity treatment: a retrospective cohort analysis.
Factors associated with weight loss response to GLP-1 analogues for obesity treatment: a retrospective cohort analysis.
Fuente:Bmj Open
Extracto:
In a real-world setting, female sex was
found to be associated with a hyper-response to GLP-1 analogue therapy for
obesity management. Other clinical factors evaluated, including diabetes status,
were not associated with the response. Future research should assess additional
variables and support the development of novel biomarkers that are associated
with weight loss response.
institución:(a) Department of Medicine, University of Alberta, Edmonton, Alberta, Canada peter.squire@medportal.ca. (b) University of British Columbia, Vancouver, British Columbia, Canada.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Opposite outcomes of triglyceride-glucose index and associated cardiovascular mortality risk in type 2 diabetes mellitus participants by different obesity criteria.
Opposite outcomes of triglyceride-glucose index and associated cardiovascular mortality risk in type 2 diabetes mellitus participants by different obesity criteria.
Fuente:Scientific Reports
Extracto:
A totally opposite
relationship appeared between TyG index and CVD mortality based on how obesity
was defined using BMI or WC in the T2DM participants, suggesting a reevaluation
of BMI's accuracy in predicting mortality risk.
Claves:Cardiovascular diasease mortality, Obesity, Triglyceride-glucose index, Type 2 diabetes mellitus
Cita:Sci Rep 2025 Jan 16; 15 (1) : 2198.
Autor/es:Huang, Hui (a) Tian, Jing (b)
institución:(a) Department of Endocrinology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China. (b) Department of Endocrinology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Prevalence of keratoconus and keratoconus suspect, and their characteristics on corneal tomography in a population-based study.
Prevalence of keratoconus and keratoconus suspect, and their characteristics on corneal tomography in a population-based study.
Fuente:Plos One
Extracto:
When
corneal tomography is unavailable, inter-eye differences in corneal parameters
may be useful screening tools for KC and KCS.
Cita:PLoS One 2025; 20 (1) : e0308892.
Autor/es:Namba, Hiroyuki (a) Maeda, Naoyuki (b)
institución:(a) Department of Ophthalmology, International University of Health and Welfare School of Medicine, Narita City, Chiba, Japan. (b) Department of Ophthalmology and Visual Sciences, Yamagata University Faculty of Medicine, Yamagata City, Yamagata, Japan.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Strategies to reduce hyperglycemia-related anxiety in elite athletes with type 1 diabetes: A qualitative analysis.
Strategies to reduce hyperglycemia-related anxiety in elite athletes with type 1 diabetes: A qualitative analysis.
Fuente:Plos One
Tipo de trabajo:Revisión
Extracto:
Elite athletes
with T1D use physiological and psychological strategies to mitigate HRA during
competition. This finding highlights the need for increased support and education
for these athletes, and advancements in technology. A multidisciplinary approach
involving healthcare professionals, athletic staff, and peer mentors could help
integrate personalized anxiety management and diabetes care strategies into
training regimens, enhancing both mental resilience and performance outcomes for
athletes with T1D.
Cita:PLoS One 2025; 20 (1) : e0313051.
Autor/es:Katz, Alexandra (a) Shulkin, Aidan (b)
institución:(a) Faculté de Médecine, Université de Montréal, Montréal, Québec, Canada. (b) School of Human Nutrition, McGill University, Montreal, Québec, Canada.
Conflicto:The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: A.K., A.S., MA.F., J.K. A.H., and M.K.T. have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. J.Y. has Dexcom and OneTouch in-kind research support. A.S.B. is a fond de recherche du Québec...
c en santé research scholar and holds grants from CIHR, JDRF and Diabete Quebec. She also has speaker’s fees from Dexcom and Abbott. R.R.L. has: 1. Research grants: Diabetes Canada, Astra-Zeneca, E Lilly, Cystic Fibrosis Canada, CIHR, FFRD, Janssen, JDRF, Merck, NIH, Novo-Nordisk, Societe Francophone du Diabete, Sanofi-Aventis, Vertex Pharmaceutical. 2. Consulting/advisory panel: Abbott, Astra-Zeneca, Bayer, Boehringer I, Dexcom, E Lilly, HLS therapeutics, INESSS, Insulet, Janssen, Medtronic, Merck, Novo- Nordisk, Pfizer, Sanofi-Aventis. 3. Honoraria for conferences: Abbott, Astra-Zeneca, Boehringer I, CPD Network, Dexcom, CMS Canadian Medical & Surgical Knowledge Translation Research group, E Lilly, Janssen, Medtronic, Merck, Novo-Nordisk, Sanofi-Aventis, Tandem, Vertex Pharmaceutical. 4. Consumable gift (in kind): E Lilly, Medtronic. 5. Unrestricted grants for clinical and educational activities: Abbott, E Lilly, Medtronic, Merck, Novo Nordisk, Sanofi-Aventis. 6. Patent: T2D risk biomarkers, catheter life. 7. Purchase fees: E Lilly (artificial pancreas).
The association between metabolomic profiles of lifestyle and the latent phase of incident chronic kidney disease in the UK Population.
The association between metabolomic profiles of lifestyle and the latent phase of incident chronic kidney disease in the UK Population.
Fuente:Scientific Reports
Extracto:
Nuclear magnetic resonance metabolomics offers new insights into
renal health, though further validation studies are needed in the future.
Claves:Chronic kidney disease, Lifestyle, Metabolomics profiles, UK Biobank
Cita:Sci Rep 2025 Jan 17; 15 (1) : 2299.
Autor/es:Jin, Tingting (a) Wu, Yunqi (b)
institución:(a) NHC Key Lab of Hormones and Development and Tianjin Key Lab of Metabolic Diseases, Tianjin Medical University Chu Hsien-I Memorial Hospital & Institute of Endocrinology, Tianjin, 300134, China. (b) NHC Key Lab of Hormones and Development and Tianjin Key Lab of Metabolic Diseases, Tianjin Medical University Chu Hsien-I Memorial Hospital & Institute of Endocrinology, Tianjin, 300134, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Department of Endocrinology and Nutrition, Hospital de la Santa Creu i Sant Pau, IR-SANT PAU, CIBERER-U747 ISCIII, ENDO-ERN, Barcelona, Spain. (b) Faculty of Medicine, University of Vic-Central University of Catalonia (UVic-UCC), Vic/Manresa, Catalonia, Spain.
Conflicto:Declaration. Competing interests: EAL receives grant support and research study drug from Tonix Pharmaceuticals and receives royalties from UpToDate. EAL and/or immediate family member holds stock in Thermo Fisher Scientific, Zoetis, Danaher Corporation, Intuitive Surgical. EAL is an inventor on US provisional patent application no. 63/467,980 (Oxytocin-based therapeutics to improve cognitive control in individuals with attention deficit hyperactivity disorder). No...
other conflicts of interest, financial or otherwise, are declared by the authors.
The incremental value of aspartate aminotransferase/alanine aminotransferase ratio combined with CURB-65 in predicting treatment outcomes in hospitalized adult community-acquired pneumonia patients with type 2 diabetes mellitus.
The incremental value of aspartate aminotransferase/alanine aminotransferase ratio combined with CURB-65 in predicting treatment outcomes in hospitalized adult community-acquired pneumonia patients with type 2 diabetes mellitus.
Fuente:Bmc Pulmonary Medicine
Extracto:
AST/ALT was identified as a
discriminative, predictive and prognostic factor for CAP patients with T2DM. The
integration of AST/ALT into CURB-65 enhanced outcome prediction for both diabetic
and non-diabetic CAP patients.
Claves:Aspartate aminotransferase/alanine aminotransferase ratio (AST/ALT), CUBR-65, Community-acquired pneumonia (CAP), Prognostic model, Type 2 diabetes mellitus (T2DM)
Cita:BMC Pulm Med 2025 Jan 17; 25 (1) : 26.
Autor/es:Zhou, Huamei (a) Zhu, Xuelei (b)
institución:(a) Department of Endocrinology, People's Hospital of Nanchuan, Chongqing, 408400, People's Republic of China. (b) Department of Endocrinology, People's Hospital of Nanchuan, Chongqing, 408400, People's Republic of China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. (b) Neuroendocrine Oncology Unit, Division of Endocrinology, Diabetes and Metabolism, Sheba Medical Center, Ramat Gan, Israel.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Association of Albumin-To-Creatinine Ratio With Diabetic Retinopathy Among US Adults (NHANES 2009-2016).
Association of Albumin-To-Creatinine Ratio With Diabetic Retinopathy Among US Adults (NHANES 2009-2016).
Fuente:Endocrinology, Diabetes & Metabolism
Extracto:
The UACR/SACR Ratio emerged as a
potentially superior DR predictor, particularly in younger patients and those
with hypertension, suggesting its utility in enhancing early detection and risk
stratification. Comprehensive evaluation of renal function and glycaemic control
biomarkers, considering age- and comorbidity-specific patterns, could improve DR
risk prediction and management. Future longitudinal studies should validate these
findings, particularly in identified high-risk subgroups, and investigate
underlying mechanisms, potentially advancing personalised DR prediction and
management strategies.
institución:(a) Department of Endocrinology and Metabolism, Second Affiliated Hospital of Chongqing Medical University, Chongqing, China. (b) Department of Ophthalmology, Chongqing University Central Hospital, Chongqing Emergency Medical Center, Chongqing, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Outcome evaluation and cost-effectiveness analysis for an integrated multidisciplinary diabetic limb salvage program: a combined observational and simulation study.
Outcome evaluation and cost-effectiveness analysis for an integrated multidisciplinary diabetic limb salvage program: a combined observational and simulation study.
Fuente:Bmj Open Diabetes Research & Care
Extracto:
The integrated multidisciplinary DEFINITE Care program
improved LEA-free survival, reduced inpatient admissions and length of stay
within 1 year and demonstrated long-term cost-effectiveness managing DFUs.
Claves:Costs and Cost Analysis, Diabetic Foot, Health Services Research, Multidisciplinary
Cita:BMJ Open Diabetes Res Care 2025 Jan 19; 13 (1)
Autor/es:Ge, Lixia (a) Sun, Yan (b)
institución:(a) Health Services and Outcomes Research, National Healthcare Group, Singapore zhiwen@gmail.com zhiwen_lo@wh.com.sg glx.lisa@gmail.com. (b) Health Services and Outcomes Research, National Healthcare Group, Singapore.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Department of Endocrinology, Bharti Hospital, Karnal, India University Center for Research & Development, Chandigarh University, India. (b) Department of Community/Family Medicine, All India Institute of Medical Sciences, Bathinda, India.
