INFLAMMATORY BOWEL DISEASE AND ASSOCIATED EXTRA-INTESTINAL INFLAMMATION OF BONE
Inflammatory bowel disease (IBD) is associated with nutritional deficiencies, decreased absorption of nutrients, decreased physical activity. (Active) IBD leads to increased generation of a mixture of inflammatory cytokines, potentially detrimental for bone, as is the commonly used corticosteroid treatment of IBD. These factors together induce osteoporosis and increased bone fracture risk. Bone-protecting strategies are being suggested.
A.A van Bodegraven
Amsterdam, Países Bajos