Endocrinología y Metabolismo

CONCENTRATION OF SEMINAL PLASMA ZINC IN VARIOUS CLASSES OF INFERTILE MALE
The present study was designed to analyze the level of seminal zinc among different groups of infertile males and to correlate it with sperm concentration, active, sluggish and immotile fractions of seminal parameters, with an objective being to establish the role of zinc. This descriptive analytical study was carried out in the Department of Reproductive Physiology/Health, Public Health Laboratories Division, National Institute of Health, Islamabad in a 5 years period from 2002 to 2006. The result showed that seminal zinc was 702.92 ± 10.60, 598.48 ± 12.95, 617.54 ± 9.55, 542.29 ± 22.75, 710.36 ± 7.87, 712.06 ± 7.96, 789.36 ± 21.33 and 762.06 ± 8.99 in azoospermic, oligozoospermic, asthenozoospermic, oligoasthenozoospermic, teratozoospermic, normozoospermic, polyzoospermic and proven fathers group, respectively. Findings of the study showed that semen zinc was several folds higher in polyzoospermic subjects as compared to other groups, while it was found to be lower in oligozoospermic, azoospermic and oligoasthenozoospermic groups. In case of proven fathers, the levels of semen zinc varied non significantly (p > 0.05) with polyzoospermic cases. It is concluded from the results of the study that decreased concentration of seminal plasma zinc affect sperm count while increased level causes decreased sperm motility.

Muhammad Shoaib Khan
Bannu, Pk

  
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HISTOPATHOLOGY OF TYPE 1 DIABETES: EMERGING PARADIGMS
The immunopathology of type 1 diabetes in the pancreas is still poorly understood. Our observations provide the first direct proof for islet autoreactivity within human islets and underscore the heterogeneous and chronic disease course.

Ken Coppieters
Ghent, BE

     
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RISK FACTORS FOR CARDIAC AND RENAL DISEASE IN HYPERTENSIVE PATIENTS WITH OVERWEIGHT OR OBESITY Artículos relacionados
Along with BP and BMI, albuminuria measured in a morning urine sample asACRis a valuable low-cost index of cardiac organ damage and increased cardiovascular risk in hypertensive patients independently by MetS. On the other hand, MetS is not an independent risk factor for cardiac damage because it does not seem to add anything more than the sum of each of its components (especially SBP and adiposity indexed by BMI) to the relationship between cardiac and renal subclinical organ damage.

Federico Guerra
Ancona, IT

     
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ANALIZAN DIFERENTES INSTRUMENTOS PARA EVALUAR LA CALIDAD DE VIDA RELACIONADA CON LA SALUD EN LA DIABETES TIPO 2 Artículos relacionados
Se realiza una revisión de las posibilidades de evaluación de la calidad de vida relacionada con la salud en pacientes con diabetes tipo 2, con detalle de las principales características de los cuestionarios más útiles en determinadas poblaciones y situaciones clínicas concretas.

Fernando Javier Sánchez Lora
Málaga, España

           
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DISLIPIDEMIA EN NIÑOS INDÍGENAS ARGENTINOS QUE HABITAN A GRANDES ALTITUDES Artículos relacionados
Se observó una alta prevalencia de dislipemia en una población de niños indígenas que viven a grandes altitudes. Sin embargo, no se verificó una asociación significativa entre los niveles de hemoglobina y de los lípidos, sugiriendo que estos niños podrían pertenecer a una población genética susceptible a padecer dislipemia.

Valeria Hirschler
Buenos Aires, Argentina

     
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