MODULATION OF DOXORUBICIN–INDUCED CYTOTOXICITY AND PHOTOCHEMOPREVENTIVE EFFECTS BY A GRAPE SEED EXTRACT
Grape seeds extract, Vitis vinifera L., variety Burgund Mare might be a chemoprotective candidate in reducing the oxidative stress and the risk for UV-induced cancer and recommend its use as such or in combination with sunscreens and/or other natural products with similar or complementary properties.

Gabriela Adriana Filip
Cluj Napoca, Ro

  

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  CONCENTRATION OF SEMINAL PLASMA ZINC IN VARIOUS CLASSES OF INFERTILE MALE
The present study was designed to analyze the level of seminal zinc among different groups of infertile males and to correlate it with sperm concentration, active, sluggish and immotile fractions of seminal parameters, with an objective being to establish the role of zinc. This descriptive analytical study was carried out in the Department of Reproductive Physiology/Health, Public Health Laboratories Division, National Institute of Health, Islamabad in a 5 years period from 2002 to 2006. The result showed that seminal zinc was 702.92 ± 10.60, 598.48 ± 12.95, 617.54 ± 9.55, 542.29 ± 22.75, 710.36 ± 7.87, 712.06 ± 7.96, 789.36 ± 21.33 and 762.06 ± 8.99 in azoospermic, oligozoospermic, asthenozoospermic, oligoasthenozoospermic, teratozoospermic, normozoospermic, polyzoospermic and proven fathers group, respectively. Findings of the study showed that semen zinc was several folds higher in polyzoospermic subjects as compared to other groups, while it was found to be lower in oligozoospermic, azoospermic and oligoasthenozoospermic groups. In case of proven fathers, the levels of semen zinc varied non significantly (p > 0.05) with polyzoospermic cases. It is concluded from the results of the study that decreased concentration of seminal plasma zinc affect sperm count while increased level causes decreased sperm motility.

Muhammad Shoaib Khan
Bannu, Pk

  

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  PROPIEDADES QUIMIOPREVENTIVAS DEL MANGO Y LA MANZANA EN EL CÁNCER DE COLON
La identificación de alimentos de origen vegetal, como el mango y la manzana, así como sus constituyentes con propiedades anticancerígenas, es una alternativa posible para el control, la prevención y el tratamiento de una neoplasia frecuente como el cáncer de colon.

Maria Elena Maldonado
Medellín, Colombia

           

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DIAGNÓSTICO RETROSPECTIVO DE LA INFECCIÓN CONGÉNITA POR CITOMEGALOVIRUS
El citomegalovirus congénito permanece infradiagnosticado en ausencia de clínica neonatal. Puede manifestarse con retraso de crecimiento intrauterino, microcefalia, hipoacusia neurosensorial, coriorretinitis, retardo mental y trastorno del espectro autista. El diagnóstico de certeza sólo se puede realizar pasadas las 3 primeras semanas mediante la detección de ADN de citomegalovirus a partir de sangre del papel de filtro del cribado neonatal.

Raquel Pinillos Pisón
Zaragoza, España

           

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RISK FACTORS FOR CARDIAC AND RENAL DISEASE IN HYPERTENSIVE PATIENTS WITH OVERWEIGHT OR OBESITY
Along with BP and BMI, albuminuria measured in a morning urine sample asACRis a valuable low-cost index of cardiac organ damage and increased cardiovascular risk in hypertensive patients independently by MetS. On the other hand, MetS is not an independent risk factor for cardiac damage because it does not seem to add anything more than the sum of each of its components (especially SBP and adiposity indexed by BMI) to the relationship between cardiac and renal subclinical organ damage.

Federico Guerra
Ancona, IT

     

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