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The increasing number of Open Access articles widens the reading offer
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SIIC created, produced and handles the AFT software that deciphers
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While most of the selected texts belong to original articles,
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MUC1 and glycan probing of CA19-9 captured biomarkers from cyst fluids and serum provides enhanced recognition of ovarian cancer.
MUC1 and glycan probing of CA19-9 captured biomarkers from cyst fluids and serum provides enhanced recognition of ovarian cancer.
Fuente:Scientific Reports
Extracto:
Our results call for further
validation in larger EOC cohorts preferentially with early stage ovarian cancers
and all major histotypes against commonly occurring benign conditions.
institución:(a) Department of Life Technologies, Division of Biotechnology, University of Turku, Medisiina D, 5th floor, Kiinamyllynkatu 10, 20520, Turku, Finland. shamima.afrinruma@utu.fi. (b) Department of Life Technologies, Division of Biotechnology, University of Turku, Medisiina D, 5th floor, Kiinamyllynkatu 10, 20520, Turku, Finland.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Personality traits of women with hereditary risk for breast/ovarian cancer versus obstetric history and cancer preventive behaviors.
Personality traits of women with hereditary risk for breast/ovarian cancer versus obstetric history and cancer preventive behaviors.
Fuente:Scientific Reports
Extracto:
Personality traits affect health-related behaviors and should be
taken into account when designing theoretical models as well as interventions
regarding health habits.
institución:(a) Practical Midwifery Science Faculty, Poznan University of Medical Sciences, Poznań, Poland. (b) Practical Midwifery Science Faculty, Poznan University of Medical Sciences, Poznań, Poland.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Reverse-engineering the FLT3-PI3K/AKT axis to enhance TILs function and improve prognosis in ovarian and cervical cancers.
Reverse-engineering the FLT3-PI3K/AKT axis to enhance TILs function and improve prognosis in ovarian and cervical cancers.
Fuente:Journal of Ovarian Research
Extracto:
This study provides the first spatially
resolved evidence of FLT3's immune-modulatory role in OC and CC, positioning it
as a promising immunotherapeutic target. FLT3-targeted strategies may offer new
options for patients resistant to conventional therapies.
institución:(a) Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, #128 Shenyang Road, Shanghai, 200090, People's Republic of China. (b) Department of Cervical, Xiamen Women and Children's Healthcare Hospital, Women's and Children's Hospital of Xiamen University, #10 Zhenhai Road, Xiamen, 361000, People's Republic of China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Interpretable Machine Learning Model for Predicting Postpartum Depression: Retrospective Study.
Interpretable Machine Learning Model for Predicting Postpartum Depression: Retrospective Study.
Fuente:Jmir Medical Informatics
Extracto:
This study developed and validated a machine learning-based
predictive model for PPD. Several significant risk factors and how they impact
the prediction of PPD were revealed. These findings provide new insights into the
early screening of individuals with high risk for PPD, emphasizing the need for
comprehensive screening approaches that include both physiological and
psychological factors.
institución:(a) Department of Gynecology and Obstetrics, West China Second University Hospital, Sichuan University, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, China. (b) West China School of Medicine, Sichuan University, Chengdu, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
The cryptic lncRNA-encoded microprotein TPM3P9 drives oncogenic RNA splicing and tumorigenesis.
The cryptic lncRNA-encoded microprotein TPM3P9 drives oncogenic RNA splicing and tumorigenesis.
Fuente:Signal Transduction and Targeted Therapy
Extracto:
Collectively, our findings functionally and clinically characterize
the "noncoding RNA"-derived microprotein TPM3P9 and thus identify potential
prognostic and therapeutic factors in renal cancer.
institución:(a) MOE Key Laboratory of Tumor Molecular Biology and State Key Laboratory of Bioactive Molecules and Druggability Assessment, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China. (b) Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Hubei Province, 441100, Xiangyang, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Effect of enhanced recovery after surgery on older patients undergoing transvaginal pelvic floor reconstruction surgery
Effect of enhanced recovery after surgery on older patients undergoing transvaginal pelvic floor reconstruction surgery
Fuente:Bmc Medicine
Tipo de trabajo:Estudio aleatorizado y controlado
Extracto:
Implementation of
the ERAS protocol can expedite post-operative recovery in older patients
undergoing transvaginal pelvic floor reconstruction surgery, achieve
opioid-sparing, alleviate pain post-operatively, and decrease the incidence of
complications. TRIAL REGISTRATION: This study was retrospectively registered with
the Chinese Clinical Trial Registry (registration number: ChiCTR2400084608). The
date of first registration was 21/05/2024.
Claves:Aged, Enhanced recovery after surgery, Gynaecological surgery, Length of stay, Pain, Pelvic organ prolapse, Postoperative nausea and vomiting
Cita:BMC Med 2025 Jan 27; 23 (1) : 43.
Autor/es:Huang, Xuezhu (a) Deng, Sisi (b)
institución:(a) Department of Anaesthesiology, Women and Children's Hospital of Chongqing Medical University (Chongqing Health Center for Women and Children), Chongqing, China. huang_xuezhu@126.com. (b) Department of Anaesthesiology, Women and Children's Hospital of Chongqing Medical University (Chongqing Health Center for Women and Children), Chongqing, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Claves:Endometriosis, Qualitative study, Roy adaptation model
Cita:Reprod Health 2025 Jan 26; 22 (1) : 8.
Autor/es:Mollazadeh, Sanaz (a) Marvi, Nahid (b)
institución:(a) Reproductive Health, Nursing and Midwifery Care Research Center, Midwifery Group, Mashhad University of Medical Sciences, Mashhad, Iran. sanaz.mollazadeh@gmail.com. (b) Reproductive Health, Department of Midwifery, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
POLE mutations in endometrial carcinoma: Clinical and genomic landscape from a large prospective single-center cohort.
POLE mutations in endometrial carcinoma: Clinical and genomic landscape from a large prospective single-center cohort.
Fuente:Cancer
Tipo de trabajo:Guía
Extracto:
The present findings confirm the absence of significant genomic
differences among POLEmut patients regardless of multiple-classifier status or
association with high-risk clinical features. Prognostic data will be essential
to elucidate the clinical significance of POLE mutations not classified as
hotspots that exhibit genomic characteristics similar to those in POLEmut
patients.
Claves:DNA polymerase epsilon (POLE), POLE hotspots, POLE multiclassifier, adjuvant therapy, comprehensive genomic profiling, endometrial cancer, molecular classification
Cita:Cancer 2025 Feb 1; 131 (3) : e35731.
Autor/es:Nero, Camilla (a) Trozzi, Rita (b)
institución:(a) Unit of Oncological Gynecology, Department of Women, Children and Public Health Sciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy. (b) Università Cattolica del Sacro Cuore, Rome, Italy.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Association between sleep problems during pregnancy and postpartum depressive symptoms as well as condition of newborn at delivery.
Association between sleep problems during pregnancy and postpartum depressive symptoms as well as condition of newborn at delivery.
Fuente:The Journal of Obstetrics and Gynaecology Research
Extracto:
This study revealed that sleep problems during
pregnancy influence postpartum depression 1 month after delivery. OSA during
pregnancy may lead to risks of delivery. Attention should be paid to sleep health
during pregnancy to ensure the mental health of mothers and a safe delivery.
Claves:Apgar score, postpartum depression, pregnancy, sleep apnea, sleep problem
Cita:J Obstet Gynaecol Res 2025 Feb; 51 (2) : e16219.
Autor/es:Komada, Yoko (a) Kawakami, Sho-Ichi (b)
institución:(a) School of Environment and Society, Institute of Science Tokyo, Tokyo, Japan. (b) Fukuda Hospital, Kumamoto, Japan.
Conflicto:Yoko Komada received honorarium from Eisai co. Sho‐Ichi Kawakami received grants or lecture fees from Tsumura & Co., Kracie Holdings, Ltd., Bayer Yakuhin, Ltd., and Pfizer Japan Inc. outside the submitted work. Azusa Ikegami received grants or lecture fee from Esai Corp., MSD Corp., Takeda Pharmaceutical, Astrazeneca Corp., Teijin Healthcare Ltd., Novartis Pharma Corp., Towa Pharmaceutica, ResMed, Taisyo Pharma. Co.,...
., Idorsia Pharmaceuticals Japan Ltd., outside the submitted work. Satoko Furuie and Rena Mori declare no competing interests.
Effect of cold atmospheric plasma on common oral pathogenic microorganisms
Effect of cold atmospheric plasma on common oral pathogenic microorganisms
Fuente:Annals of Medicine
Tipo de trabajo:Revisión
Extracto:
CAP is effective against various oral pathogenic microorganisms, and it is
anticipated to offer a new approach to treating oral infectious diseases. The
future objective is to precisely adjust the parameters of CAP to ensure safety
and efficacy, and subsequently develop a comprehensive CAP treatment protocol.
Achieving this objective is crucial for the clinical application of CAP, and
further research is necessary.
Claves:Cold atmospheric plasma, antimicrobial, oral infectious disease, oral microorganisms, reactive oxygen and nitrogen species
Cita:Ann Med 2025 Dec; 57 (1) : 2457518.
Autor/es:Xin, Jiajun (a) Zhang, Hao (b)
institución:(a) Department of Prosthodontics, Hospital of Stomatology, Jilin University, Changchun, People's Republic of China. (b) Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, Changchun, People's Republic of China.
Conflicto:No potential conflict of interest was reported by the author(s).
Implementing IPE in a Workplace Setting: Educational Design Research Promotes Transformative Participation.
Implementing IPE in a Workplace Setting: Educational Design Research Promotes Transformative Participation.
Fuente:Perspectives On Medical Education
Tipo de trabajo:Revisión
Extracto:
This resulted in an evidence informed, interprofessional
cocreation process in and with the workplace that was aligned with existing
workflow and organizational culture.
Cita:Perspect Med Educ 2025; 14 (1) : 31-43.
Autor/es:Versluis, Marco A C (a) Zöllner, Lizzy-Sara (b)
institución:(a) Department of Obstetrics and Gynaecology, University Medical Center Groningen, The Netherlands. (b) Wenckebach Institute, Lifelong Learning, Education and Assessment Research Network (LEARN), University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands.
Conflicto:The authors have no competing interests to declare.
Extracto:
This
review forms part of the foundational work for the development of a global
monitoring framework which would be able to monitor progress towards the
provision of universal high quality perinatal mental health care.
Cita:PLoS One 2025; 20 (1) : e0317998.
Autor/es:Layton, Elly (a) Roddy Mitchell, Alexandra (b)
institución:(a) Maternal, Child and Adolescent Health Program, Burnet Institute, Melbourne, Australia. (b) Maternal, Child and Adolescent Health Program, Burnet Institute, Melbourne, Australia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Extracto:
This was the first
SRMA from Saudi Arabia which emphasized the priority to focus on vaccine-related
factors as main/key strategy of COVID-19 vaccines' drivers to convince parents in
a logical way based on accurate cumulative and emerging scientific data about
efficacy and safety of COVID-19 vaccines to optimize their uptake by
children/adolescents. This SRMA can provide valuable insights for development of
evidence-based policies to improve parental willingness to vaccinate children,
which is crucial for controlling SARS-CoV-2 spread and promoting herd immunity in
the community particularly if the virus continues to pose a major threat.
institución:(a) Faculty of Medicine in Rabigh, Department of Pediatrics, King Abdulaziz University, Jeddah, Saudi Arabia. (b) Faculty of Medicine, Department of Pediatrics, Mansoura University Children's Hospital, Mansoura, Egypt.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Designing the First Pregnancy Guaranteed Income Program in the United States: Qualitative Needs Assessment and Human-Centered Design to Develop the Abundant Birth Project.
Designing the First Pregnancy Guaranteed Income Program in the United States: Qualitative Needs Assessment and Human-Centered Design to Develop the Abundant Birth Project.
Fuente:Jmir Formative Research
Extracto:
The formative design process maximized
community input and shared decision-making to co-design a guaranteed income
program for Black and Pacific Islander women and people. Our upstream approach
and community research model can inform the development of public health and
social service programs.
Claves:Abundant Birth Project, Black, behavioral interventions, community-centered, economics, financial stress, first pregnancy, infant, infant health, maternal and child health, pregnancy, programs (evaluation and funding), public health, qualitative research methods, racial health
Cita:JMIR Form Res 2025 Jan 27; 9 : e60829.
Autor/es:Karasek, Deborah (a) Williams, Jazzmin C (b)
institución:(a) School of Public Health, Oregon Health & Science University and Portland State University, Portland, OR, United States. (b) Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, San Francisco, United States.
Magnitude of immediate postpartum anaemia and associated factors among mothers at selected public hospitals in North Shoa Zone, Oromia regional state, Ethiopia: a cross-sectional study in 2022.
Magnitude of immediate postpartum anaemia and associated factors among mothers at selected public hospitals in North Shoa Zone, Oromia regional state, Ethiopia: a cross-sectional study in 2022.
Fuente:Bmj Open
Extracto:
The magnitude of immediate postpartum
anaemia was a moderate public health problem. Factors such as postpartum
haemorrhage, history of abortion, rural residence, poor adherence to iron and
folic acid supplementation and MUAC <23 cm were significantly associated with
immediate postpartum anaemia. Strategies should be put in place to encourage
early identification and preventive action for the risk factors of immediate
postpartum anaemia.
Claves:Anaemia, OBSTETRICS, Public health
Cita:BMJ Open 2025 Jan 27; 15 (1) : e081405.
Autor/es:Nigusu, Genanew (a) Wakgari, Negash (b)
institución:(a) Midwifery, Dilla University College of Health Sciences, Dilla, Ethiopia nigusugenanew@gmail.com. (b) Department of Midwifery, Ambo University College of Medicine and Public Health, Ambo, Oromia, Ethiopia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Body composition and physical performance of mountain bike athletes.
Body composition and physical performance of mountain bike athletes.
Fuente:Scientific Reports
Extracto:
A higher percentage of fat results in longer race
times, while greater muscle mass and hydration result in shorter race times.
Claves:Athletic performance, Body composition, Cycling, Handgrip strength
Cita:Sci Rep 2025 Jan 27; 15 (1) : 3329.
Autor/es:Carvalho de Moura, Rayane (a) de Moura Costa, Crislane (b)
institución:(a) Postgraduate Program in Food and Nutrition at the Federal University of Piauí (PPGAN/UFPI), Teresina, Piauí, Brazil. rayane_cm@hotmail.com. (b) Nucleus of Study in Physiology Applied to Performance and Health (NEFADS), Departmenty of Biophysics and Physiology, Federal University of Piauí, 2131, Av. São Francisco, Comprida, Teresina, Piauí, 64076-178, Brazil. rayane_cm@hotmail.com.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Adverse birth outcome and associated factors among mothers with antepartum hemorrhage in public hospitals Tigray, northern Ethiopia, 2020.
Adverse birth outcome and associated factors among mothers with antepartum hemorrhage in public hospitals Tigray, northern Ethiopia, 2020.
Fuente:Bmc Pregnancy and Childbirth
Extracto:
ND RECOMMENDATION:
adverse birth outcomes were higher in magnitude and the higher public health
problem in the Tigray region. Predictors could be minimized by strengthening
antenatal care follow up, ensuring early arrival to health institution, and
focusing on rural area.
Claves:Adverse birth outcome, Antepartum hemorrhage, Associated factors, Tigray region
Cita:BMC Pregnancy Childbirth 2025 Jan 27; 25 (1) : 78.
Autor/es:Abraha, Tomas Amare (a) Gebremariam, Gebremedhin Kinfe (b)
institución:(a) College of Health Science, department of midwifery, Mekelle University, Mekelle, Ethiopia. tomasacsh@gmail.com. (b) College of Health Science, department of midwifery, Adigrat University, Adigrat, Ethiopia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
A comparative analysis of methods of preinduction cervical ripening and induction of labor in Poland and in Germany (Part II): maternal and neonatal outcomes.
A comparative analysis of methods of preinduction cervical ripening and induction of labor in Poland and in Germany (Part II): maternal and neonatal outcomes.
Fuente:Bmc Pregnancy and Childbirth
Extracto:
First- and
second-degree perineal tears were more frequent in Germany.
Claves:Induction of labor, Preinduction and induction of labor in Poland and Germany, Preinduction cervical ripening
Cita:BMC Pregnancy Childbirth 2025 Jan 27; 25 (1) : 72.
Autor/es:Kleszcz, Agnieszka K (a) Ćwiek, Dorota (b)
institución:(a) Department of Obstetrics and Pathology of Pregnancy, Pomeranian Medical University in Szczecin, ul. Żołnierska 48, Szczecin, 71-210, Poland. a.kleszcz@gesundheit-akademie.de. (b) Hochschule für Gesundheitsfachberufe in Eberswalde, Schicklerstraße 20, 16225, Eberswalde, Germany.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
The effect of a comprehensive intervention on anthropometric indices, dietary intake, and physical activity of adolescent boys with overweight.
The effect of a comprehensive intervention on anthropometric indices, dietary intake, and physical activity of adolescent boys with overweight.
Fuente:Bmc Pediatrics
Extracto:
A comprehensive lifestyle modification intervention which
covers both school and individual levels may positively influence BMI, body fat,
calorie intake, and distance and duration of physical activity in adolescents.
Thus, adopting multifaceted strategies using the Ottawa Charter framework may be
considered as an effective approach to managing obesity in adolescents.
institución:(a) Department of Clinical Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. (b) Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Evaluation of placental growth factor, Vitamin D, and systemic inflammatory index as predictive biomarkers for preeclampsia severity
Evaluation of placental growth factor, Vitamin D, and systemic inflammatory index as predictive biomarkers for preeclampsia severity
Fuente:Bmc Pregnancy and Childbirth
Tipo de trabajo:Estudio de cohortes
Extracto:
Lower levels of PlGF and
Vitamin D, along with higher PIV, were independently associated with an increased
risk of severe preeclampsia. These findings suggest that PlGF, Vitamin D, and PIV
are valuable biomarkers for early identification of high-risk preeclampsia
patients, potentially aiding in timely intervention and improved outcomes.
Cita:BMC Pregnancy Childbirth 2025 Jan 27; 25 (1) : 75.
Autor/es:Han, Xiaoyan (a) Yang, Hua (b)
institución:(a) Department of Gynecology and Obstetrics, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China. hxy13810205891@126.com. (b) Department of Gynecology and Obstetrics, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
