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Molecular mechanism of aberrant decidualization in adenomyosis leading to reduced endometrial receptivity.
Molecular mechanism of aberrant decidualization in adenomyosis leading to reduced endometrial receptivity.
Fuente:Frontiers in Endocrinology
Extracto:
Correcting
the abnormal expression of molecules in endometrial stromal cells in the
endometrium of patients with adenomyosis may become the focus of research to
improve endometrial receptivity and increase the pregnancy rate.
institución:(a) Department of Gynecology, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China. (b) Department of Gynecology, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Study on the changes and influencing factors of depression in Chinese women with cancer: an analysis based on CHARLS panel data.
Study on the changes and influencing factors of depression in Chinese women with cancer: an analysis based on CHARLS panel data.
Fuente:Frontiers in Public Health
Extracto:
The depressive state
among Chinese women with cancer is alarming. In view of this, there is an urgent
need for introducing more supportive policies aimed at improving psychological
health, developing tailored measures to address the specific needs of different
groups, intensifying efforts to standardize the diagnosis and treatment of
depression, particularly for those in rural areas, central and western regions,
and among individuals with lower educational levels. Additionally, the role of
social participation activities, such as visiting neighbors and exercising,
should be given full play to alleviate depressive symptoms.
Claves:depression, development trends, influencing factors, panel stochastic trend model, women with cancer
Cita:Front Public Health 2024; 12 : 1485196.
Autor/es:Wang, Na (a) Chang, Mengran (b)
institución:(a) Gynecology Department, First Affiliated Hospital of Bengbu Medical University, Bengbu, China. (b) Gynecology Department, First Affiliated Hospital of Bengbu Medical University, Bengbu, China.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Early detection and a treatment bundle strategy for postpartum haemorrhage: a mixed-methods process evaluation.
Early detection and a treatment bundle strategy for postpartum haemorrhage: a mixed-methods process evaluation.
Fuente:The Lancet. Global Health
Tipo de trabajo:Estudio aleatorizado
Extracto:
TRANSLATION: For the Swahili translation of the abstract see Supplementary
Materials section.
Cita:Lancet Glob Health 2025 Feb; 13 (2) : e329-e344.
Autor/es:Bohren, Meghan A (a) Miller, Suellen (b)
institución:(a) Gender and Women's Health Unit, Nossal Institute for Global Health, School of Population and Global Health, University of Melbourne, Melbourne, VIC, Australia. Electronic address: meghan.bohren@unimelb.edu.au. (b) Department of Obstetrics and Reproductive Sciences, School of Medicine, University of California San Francisco, CA, USA.
Conflicto:Declaration of interests SMi's University (University of California San Francisco) holds the licence for the Trademark name “LifeWrap”. The LifeWrap is the name of one first-aid device used in refractory postpartum haemorrhage, the non-pneumatic anti-shock garment (NASG). The manufacturer of the LifeWrap NASG pays the University of California a royalty for the use of the name. GJH has conceived a...
ed a reusable device for postpartum blood loss monitoring, the Maternawell Tray, which is marketed by Maternova, a global women's health solutions company who hold the intellectual property. GJH benefits from sales of the device. The E-MOTIVE research project was supported by an investment grant (INV-001393) from the Bill and Melinda Gates Foundation to the University of Birmingham, and via subcontracts to coauthors’ research institutions.
Application of a methodological framework for the development and multicenter validation of reliable artificial intelligence in embryo evaluation.
Application of a methodological framework for the development and multicenter validation of reliable artificial intelligence in embryo evaluation.
Fuente:Reproductive Biology and Endocrinology Rb&e
Extracto:
Strong AI performance across multiple datasets demonstrates the
value of our four-step methodology in developing and validating the AI as a
reliable adjunct to embryo evaluation.
Claves:Artificial intelligence, Embryo ranking, Machine learning, Time lapse imaging
Cita:Reprod Biol Endocrinol 2025 Jan 31; 23 (1) : 16.
Conflicto:Declarations. Ethics approval and consent to participate: All collected data were de-identified and retrospectively collected prior to data analysis. Agreement to share data was authorized in the Software Licensing Agreement between each participating clinic and AIVF. IRB Study approval was obtained from the local independent review boards of IVI Valencia (Spain) (ID number 1902-VLC-018-MM), Assuta Ramat Hachayal (Israel) (ID number...
ASMC 68 − 18), Embryolab (Greece) (ID number 05/2019) and Clevelend Clinic (USA) (ID number 20–766). In Portugal, Ireland, Germany, Korea, and the Czech Republic, the study was deemed negligible risk authorized under the terms of the signed licensing agreement. Consent to participate was not applicable. Consent for publication: Not applicable. Competing interests: D.G., M.S., Y.T., Y.A., and N.L. are paid employees of AIVF. D.G. and D.S.S. have stock and share ownership of AIVF. M.M. is a member of the AIVF scientific advisory board team. C.L.C. is on the editorial board for the Journal of Assisted Reproduction and Genetics.
Comparative efficacy of lumbar and pelvic support on pain, disability, and motor control in women with postpartum pelvic girdle pain: a three-armed randomized controlled trial.
Comparative efficacy of lumbar and pelvic support on pain, disability, and motor control in women with postpartum pelvic girdle pain: a three-armed randomized controlled trial.
Fuente:Bmc Musculoskeletal Disorders
Tipo de trabajo:Estudio aleatorizado y controlado
Extracto:
For women with pregnancy-related PPGP, both lumbar and pelvic
supports were beneficial for decreasing pain and disability symptoms. Lumbar
support showed better results for managing PPGP than pelvic support. CLINICAL
TRIAL REGISTRATION: Iranian Registry of Clinical Trials IRCT20150210021034N11.
Date of registration: April 31, 2021. Available at:
https://irct.behdasht.gov.ir/trial/70670.
Claves:Disability, Lumbosacral orthosis, Motor control, Pain, Postpartum, Sacroiliac joint
Cita:BMC Musculoskelet Disord 2025 Feb 1; 26 (1) : 100.
institución:(a) Musculoskeletal Research Center, School of Rehabilitation Sciences, Isfahan University of Medical Sciences, Hezar Jerib St, Isfahan, Iran. (b) Department of Obstetrics & Gynecology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Are facility service delivery models meeting the sexual and reproductive health needs of adolescents in Sub-Saharan Africa? A qualitative evidence synthesis.
Are facility service delivery models meeting the sexual and reproductive health needs of adolescents in Sub-Saharan Africa? A qualitative evidence synthesis.
Fuente:Bmc Health Services Research
Tipo de trabajo:Revisión sistemática
Extracto:
Facility-based SRH service delivery models can improve access to
information and services when complemented with community-based interventions,
adolescent-friendly providers, and assurance of service accessibility. However,
significant gaps, such as healthcare providers' negative attitudes and
behaviours, concerns about privacy and confidentiality, financial constraints,
and transportation challenges, limit their effectiveness. These findings call for
expanding out-of-facility services, adopting mHealth solutions, enhancing
provider training, strengthening confidentiality, and reducing financial barriers
to ensure equitable and effective access to services.
Claves:Adolescent-friendly services, Adolescents, Delivery models, Health facilities, Sexual and reproductive health, Sub-Saharan Africa
Cita:BMC Health Serv Res 2025 Feb 1; 25 (1) : 193.
Autor/es:Sanyang, Yusupha (a) Sanyang, Saikou (b)
institución:(a) Department of International Public Health Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3, 5QA, UK. ysanyang@utg.edu.gm. (b) Department of Nursing and Reproductive Health, University of The Gambia, Serrekunda, The Gambia. ysanyang@utg.edu.gm.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Pattern and Predictors of Maternal Healthcare Services Utilization among Women of Reproductive Age in Lagos, Nigeria.
Pattern and Predictors of Maternal Healthcare Services Utilization among Women of Reproductive Age in Lagos, Nigeria.
Fuente:Annals of Global Health
Extracto:
Conclusion: This
study reveals high awareness and utilization of maternal health services but
highlights room for improvement in early antenatal care registration and
postnatal care beyond the child's immunization.
Claves:Antenatal care services, Childbirth services, Lagos, Maternal Healthcare Services, Nigeria, Pattern, Postnatal care services, Predictors, Utilization
Cita:Ann Glob Health 2025; 91 (1) : 7.
Autor/es:Oluwole, Esther Oluwakemi (a) Roberts, Alero Ann (b)
institución:(a) Department of Community Health & Primary Care, College of Medicine, University of Lagos, Lagos, Nigeria. (b) Department of Community Health & Primary Care, College of Medicine, University of Lagos, Lagos, Nigeria.
Conflicto:The authors declare that they have no actual or potential competing interests concerning the research, authorship, and/or publication of this article. All authors certify their responsibility for the manuscript.
Serum-derived small extracellular vesicles as biomarkers for predicting pregnancy and delivery on assisted reproductive technology in patients with endometriosis.
Serum-derived small extracellular vesicles as biomarkers for predicting pregnancy and delivery on assisted reproductive technology in patients with endometriosis.
Fuente:Frontiers in Endocrinology
Extracto:
DISCUSSION: Further studies are required to examine the functional importance of
these miRNAs to elucidate the pathological mechanisms of endometriosis and
pregnancy.
institución:(a) Department of Obstetrics and Gynecology, Nagoya University Graduate School of Medicine, Nagoya, Japan. (b) Department of Obstetrics and Gynecology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Diminished ovarian reserve is associated to euploidy rate: a single center study.
Diminished ovarian reserve is associated to euploidy rate: a single center study.
Fuente:Frontiers in Endocrinology
Extracto:
Our findings suggest that AMH levels are
associated with embryo ploidy rate. These insights could enhance counseling
practices in assisted reproductive technology (ART), offering patients a more
detailed understanding of their infertility prognosis and the factors influencing
IVF outcomes.
institución:(a) Division of Gynecology and Reproductive Medicine, Department of Gynecology, Fertility Center, Istituto di Ricerca e Cura a Carattere Scientifico (IRCCS) Humanitas Research Hospital, Milan, Italy. (b) Division of Gynecology and Reproductive Medicine, Department of Gynecology, Fertility Center, Istituto di Ricerca e Cura a Carattere Scientifico (IRCCS) Humanitas Research Hospital, Milan, Italy.
Conflicto:The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Reproduction outcomes and prognostic significance of pregnancy after nasopharyngeal carcinoma treatment.
Reproduction outcomes and prognostic significance of pregnancy after nasopharyngeal carcinoma treatment.
Fuente:Annals of Medicine
Extracto:
Pregnancy after NPC
treatment was not associated with adverse clinical outcomes. Abortion may not be
a remedial choice post-treatment in patients with NPC.
institución:(a) State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Road East, Guangzhou, PR China. (b) Department of Radiology, Sun Yat-sen University Cancer Center, Guangzhou, PR China.
Conflicto:No potential conflict of interest was reported by the author(s).
Autor/es:Bondy, Suraya (a) McClymont, Elisabeth (b)
institución:(a) Department of Obstetrics and Gynaecology, University of British Columbia, Vancouver, Canada. (b) Department of Obstetrics and Gynaecology, University of British Columbia, Vancouver, Canada.
Conflicto:EM has received salary support in the form of postdoctoral fellowships from Michael Smith Health Research BC and the Canadian HIV Trials Network/CANFAR. J Barrett has received funding and honoraria from Ferring Pharmaceuticals and is a medical advisor for a technical company (MYANT), which manufactures and sells textile-based smart technology. IB is funded by a “Fond de Recherche du Québec...
bec – Santé” salary award. RD is supported by a Tier-II Canada Research Chair in Maternal Health (CRC-2021-00337). DE–C is an investigator on projects funded by Moderna, funds are paid to the research institution. A donation from Merck to the The Centre for Vaccine Preventable Diseases, at the Dalla Lana School of Public Health, supported the salary of SF from April 2020 to February 2023. SF does not receive funding directly from Merck or any personal payment or direct funds from vaccine manufacturers to support her research. VP was a lecturer for a talk sponsored by Sanofi-Pasteur in June 2022. MS is supported via salary awards from BC Children’s Hospital Foundation and Michael Smith Foundation for Health Research. MS has been an investigator on projects funded by GlaxoSmithKline, Merck, Moderna, Pfizer, Sanofi-Pasteur, Seqirus, Symvivo, and VBI Vaccines. All funds were paid to his institute, and he has not received any personal payments. MT-B has received speaking honoraria not related to this work as well as education and research grants from Ferring Pharmaceuticals. DM has received past funding from Merck (outside the submitted work). All other authors report there are no competing interests to declare. Study authors SB, EM, AA, JA, IF, JB, TB, EC, RD, DE-C, SF, VK, GO, VP, MS, HS, JS, MBT, and DM previously submitted an abstract outlining preliminary findings of this study to the 2023 Canadian Immunization Conference.
Tone or tissue? A comparison of trends and risk factors of severe postpartum hemorrhage according to uterine atony or retained tissue in a hospital setting.
Tone or tissue? A comparison of trends and risk factors of severe postpartum hemorrhage according to uterine atony or retained tissue in a hospital setting.
Fuente:Plos One
Extracto:
The observed increased rate of PPH
in the study period was mainly driven by an increase in atonic PPH, while the
rate of severe PPH caused by retained tissue remained stable. The proportion
caused by retained tissue was highest among the most severe cases of PPH. The
reason for the increase in severe PPH due to uterine atony, but not retained
tissue was not clear, but we speculate that it may be a combination of increasing
risk factors with increased awareness of PPH.
institución:(a) Norwegian Research Centre for Women's Health, Oslo University Hospital, Oslo, Norway. (b) Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Fourth-year medical student at Yale School of Medicine in New Haven, Connecticut. (b) Clinical research assistant in the Division of Minimally Invasive Gynecologic Surgery at Brigham and Women's Hospital in Boston, Massachusetts.
Asymptomatic or mild COVID-19 infection in women prior to oocyte retrieval has no impact on embryo laboratory outcomes: a retrospective study.
Asymptomatic or mild COVID-19 infection in women prior to oocyte retrieval has no impact on embryo laboratory outcomes: a retrospective study.
Fuente:Journal of Ovarian Research
Extracto:
Asymptomatic or mild COVID-19 infection
prior to oocyte retrieval may not has a significant negative effect on ovulation
induction outcomes or laboratory outcomes, although the number of Gn days and
dose of Gn may increase. In addition, we should pay attention to infertile women
recovering from COVID-19 infection and be aware of the significant reduction in
the number of high-quality blastocysts in this population.
institución:(a) Department of Reproductive Center, Obstetrics and Gynecology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China. (b) Department of Reproductive Center, Obstetrics and Gynecology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Consecutive prediction of adverse maternal outcomes of preeclampsia, using the PIERS-ML and fullPIERS models: A multicountry prospective observational study.
Consecutive prediction of adverse maternal outcomes of preeclampsia, using the PIERS-ML and fullPIERS models: A multicountry prospective observational study.
Fuente:Plos Medicine
Extracto:
In this study,
we have evaluated the performance of the fullPIERS and PIERS-ML models for
consecutive prediction. We observed deteriorating performance of both models over
time. We recommend using the models for consecutive prediction with greater
caution and interpreting predictions with increasing uncertainty as the pregnancy
progresses. For clinical practice, models should be adapted to retain accuracy
when deployed serially. The performance of future models can be compared with the
results of this study to quantify their added value.
institución:(a) Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands. (b) Department of Mathematics and Statistics, University of Strathclyde, Glasgow, United Kingdom.
Conflicto:PvD, KK, LAM, PM, and TM-C have an intellectual property claim regarding the PIERS-AI machine learning-based suite of models (PE962099GB). No other conflicts are declared.
The journal of maternal-fetal & neonatal medicine the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Selección SIIC: 6 Febrero, 2025
The journal of maternal-fetal & neonatal medicine the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
The fetal cerebral Doppler in the last weeks of pregnancy can select very small fetuses unlikely to present intrapartum compromise.
The fetal cerebral Doppler in the last weeks of pregnancy can select very small fetuses unlikely to present intrapartum compromise.
Fuente:The Journal of Maternal-fetal & Neonatal Medicine The Official Journal of The European Association of Perinatal Medicine, The Federation of Asia and Oceania Perinatal Societies, The International Society of Perinatal Obstetricians
Extracto:
The cerebral Doppler can
select a group of very small fetuses that are less likely to experience IC. These
fetuses might be to some extent constitutionally small and might be candidates
for a more conservative and individualized management.
Claves:Cerebroplacental ratio, fetal growth restriction, intrapartum compromise, middle cerebral artery, small for gestational age
Autor/es:Morales-Roselló, José (a) Martínez-Varea, Alicia (b)
institución:(a) Servicio de Obstetricia y Ginecología, Hospital Universitario y Politécnico La Fe, Valencia, Spain. (b) Departamento de Pediatría, Obstetricia y Ginecología, Universidad de Valencia, Valencia, Spain.
International journal of gynecological cancer official journal of the International Gynecological Cancer Society
Selección SIIC: 6 Febrero, 2025
International journal of gynecological cancer official journal of the International Gynecological Cancer Society
Comprehensive evaluation of genomic and functional assays for homologous recombination deficiency with high-grade epithelial ovarian cancer: Platinum sensitivity and prognosis.
Comprehensive evaluation of genomic and functional assays for homologous recombination deficiency with high-grade epithelial ovarian cancer: Platinum sensitivity and prognosis.
Fuente:International Journal of Gynecological Cancer Official Journal of The International Gynecological Cancer Society
Extracto:
Genomic scar score, given by
AmoyDx HRD Complete Panel, was most associated with the efficacy of platinum
treatment in patients with high-grade ovarian cancer. Validation is warranted via
prospective studies.
Cita:Int J Gynecol Cancer 2025 Jan; 35 (1) : 100031.
Autor/es:Feng, Zheng (a) Zhu, Changbin (b)
institución:(a) Fudan University Shanghai Cancer Center, Department of Gynecologic Oncology, Shanghai, China; Fudan University, Shanghai Medical College, Department of Oncology, Shanghai, China. (b) Amoy Diagnostics Co, Ltd, Department of Translational Medicine, Xiamen, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Establishment of a human ovarian endometrioid carcinoma cell line by constitutive expression of cyclin-dependent kinase 4, cyclin D1 and telomerase reverse transcriptase.
Establishment of a human ovarian endometrioid carcinoma cell line by constitutive expression of cyclin-dependent kinase 4, cyclin D1 and telomerase reverse transcriptase.
Fuente:Human Cell
Extracto:
These findings indicate that constitutive expression of CDK4(R24C), cyclin D1 and
TERT genes may be an option to establish cell lines from low-grade cancers,
including ovarian endometrioid carcinoma.
institución:(a) Department of Tumor Pathology, Faculty of Medical Sciences, University of Fukui, 23-3 Matsuoka-Shimoaizuki, Eiheiji, Fukui, 910-1193, Japan. (b) Department of Pharmacology, Kansai Medical University, Hirakata, Japan.
Conflicto:Declarations. Conflict of interest: The authors declare that they have no conflict of interest. Ethical approval: The use of fresh human ovarian cancer tissues was approved by the Research Ethics Committee of University of Fukui (reference number 20200176, approved on February 22, 2021). The analysis of human ovarian cancer tissues was approved by the Research Ethics Committee of University of...
Fukui (reference number 20200024, approved on May 19, 2020). Informed consent: Written informed consent was obtained from the patient for the use of clinical specimens for medical research.
The journal of maternal-fetal & neonatal medicine the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Selección SIIC: 6 Febrero, 2025
The journal of maternal-fetal & neonatal medicine the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
A prospective observational multicenter cohort study of maternal serum sFlt-1 and PlGF concentration in prediction of adverse neonatal outcomes in small for gestational age newborns delivered ?34 weeks of gestation.
A prospective observational multicenter cohort study of maternal serum sFlt-1 and PlGF concentration in prediction of adverse neonatal outcomes in small for gestational age newborns delivered ?34 weeks of gestation.
Fuente:The Journal of Maternal-fetal & Neonatal Medicine The Official Journal of The European Association of Perinatal Medicine, The Federation of Asia and Oceania Perinatal Societies, The International Society of Perinatal Obstetricians
Tipo de trabajo:Estudio de cohortes
Extracto:
In pregnancies
with SGA, fetuses measurements of maternal serum sFlt-1 or PlGF provide poor
prediction of adverse neonatal outcomes.
Autor/es:Kosińska-Kaczyńska, Katarzyna (a) Chaberek, Katarzyna (b)
institución:(a) Department of Obstetrics, Perinatology and Neonatology, Center of Postgraduate Medical Education, Warsaw, Poland. (b) Department of Obstetrics, Perinatology and Neonatology, Center of Postgraduate Medical Education, Warsaw, Poland.
Clinical characteristics and risk factors to high-grade vaginal intraepithelial neoplasia: a single-institution study.
Clinical characteristics and risk factors to high-grade vaginal intraepithelial neoplasia: a single-institution study.
Fuente:Bmc Women's Health
Extracto:
High-grade VaIN is significantly associated with older age. The
sensitivity of cytology and HPV testing for detecting high-grade VaIN is
comparable to that for high-grade CIN. Thus, these tests may facilitate early
detection of high-grade VaIN.
Claves:Cervical intraepithelial neoplasia, Cytology, High‐grade vaginal intraepithelial neoplasia, Human papillomavirus
Cita:BMC Womens Health 2025 Feb 1; 25 (1) : 44.
Autor/es:Lu, Min (a) Hong, Xiaoshan (b)
institución:(a) Department of Gynecology, Guangdong Women and Children Hospital, 521 Xingnan Avenue, Panyu District, Guangzhou, 511442, China. lumin198938@163.com. (b) Department of Gynecology, Guangdong Women and Children Hospital, 521 Xingnan Avenue, Panyu District, Guangzhou, 511442, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
