Farmacología

DIURETICS OR ARB ADDED TO CCB IN TREATMENT OF HYPERTENSION
Long-term combination therapy with amlodipine plus amiloride/hydrochlorothiazide or amlodipine plus telmisartan was effective and safe for the high-risk hypertensive patients in China.

Fanghong Lu
Jinan, Cn

  
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SIMULTANEOUS ESTIMATION IN COMBINED DOSAGE FORMS USING UV SPECTROSCOPY
Simultaneous determination of combined pharmaceutical dosage forms, followed by validation, without prior separation, by different simple analytical techniques are reported in this paper. The proposed procedures are rapid, simple, accurate, precise, require no preliminary separation steps, and can be used for routine analysis of drugs in quality control laboratories.

Kareti Srinivasa Rao
Berhampur, In

  
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INNOVATIVE APPROACHES TO NOVEL SCAFFOLDS AND STRATEGIES FOR INFECTIOUS DISEASES
Our study indicates validity of claims in Ayurved, if medicinal plants selected on basis of its documented use, it leads to more hits which can be scientifically manipulated to find therapies for diseases. In treating infectious diseases, we hope ancient science can contribute to find solutions in developing countries.

Priyanka Jadhav
Gainesville, Us

  
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APLICACION DE LA VITAMINA B12 EN EL TRATAMIENTO DE LA ENFERMEDAD DE CHAGAS
El tratamiento de la enfermedad de Chagas tiene eficacia limitada y efectos colaterales indeseados. Sobre un modelo murino de esta enfermedad, la administración de vitamina B12 permitió controlar la parasitemia, modificando el estado oxidativo del parásito, sin generar citotoxicidad. Nuevas alternativas terapéuticas podrían surgir combinando la vitamina B12 y menores dosis de los antiparasitarios actualmente en uso.

Maria Elisa Lombardo
Buenos Aires, Argentina

     
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  T2DM: DAPAGLIFLOZIN, METFORMIN XR, OR BOTH
In treatment-naïve patients with type 2 diabetes (T2D), initial combination therapy with dapagliflozin + extended-release metformin (MET XR) resulted in significant improvements in glycaemic and weight outcomes. Dapagliflozin + MET XR provided superior glycaemic benefits to monotherapy with either agent. The combination treatment was generally well tolerated.

James F. List
Princeton, New Jersey, Us

  
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