REVISION DE LOS MODELOS MURINOS DE HIPERTENSION EXPERIMENTAL

(especial para SIIC © Derechos reservados)
La hipertensión es un trastorno multifactorial, lo que da lugar a que exista un gran número de modelos experimentales, tanto de su variedad genética como, en su mayor parte, inducidos por diferentes procedimientos: quirúrgicos, farmacológicos, metabólicos, y manipulados genéticamente.
Autor:
Guadalupe Baños
Columnista Experto de SIIC

Institución:
Instituto Nacional de Cardiología "Ignacio Chávez"


Artículos publicados por Guadalupe Baños
Coautores
Israel Pérez-Torres* Mohammed El Hafidi** 
Ph.D. Investigador Asociado, Instituto Nacional de Cardiología "Ignacio Chávez", Tlalpan, México*
Ph.D. Investigador Titular, Instituto Nacional de Cardiología "Ignacio Chávez", Tlalpan, México**
Recepción del artículo
21 de Mayo, 2008
Aprobación
9 de Junio, 2008
Primera edición
3 de Diciembre, 2008
Segunda edición, ampliada y corregida
7 de Junio, 2021

Resumen
El estudio de la hipertensión se ha realizado en una gran variedad de modelos así como en diferentes especies. Entre éstas quizá las más comunes son las de roedores, la rata y el ratón, no solamente por el relativo bajo costo de su mantenimiento y facilidad de manejo, sino porque frecuentemente el cuadro patológico que desarrollan es muy similar al que se observa en los humanos. Se revisan algunos resultados obtenidos con el uso de modelos en experimentos realizados en nuestro laboratorio, así como datos recientes de otros autores.

Palabras clave
hipertensión experimental, modelos en roedores


Artículo completo

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Extensión:  +/-8.47 páginas impresas en papel A4
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Abstract
Hypertension studies have been carried out in a large variety of models and animal species. Probably the most commonly model used is rodents, rat or mice, not only on account of their comparatively low maintenance cost and easy handling, but also because the pathology observed in these animals is similar to the one observed in humans. Some results obtained from experiments carried out in this laboratory using those models, as well as from other researchers, are reviewed in this work.

Key words
experimental hypertension, rodent models


Clasificación en siicsalud
Artículos originales > Expertos de Iberoamérica >
página   www.siicsalud.com/des/expertocompleto.php/

Especialidades
Principal: Cardiología
Relacionadas: Diabetología, Educación Médica, Endocrinología y Metabolismo, Farmacología, Genética Humana, Medicina Farmacéutica, Medicina Interna, Medicina Veterinaria



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Enviar correspondencia a:
Guadalupe Baños, Instituto Nacional de Cardiología "Ignacio Chávez", 14080, Juan Badiano 1. Col. Sección XVI, Tlalpan, México
Patrocinio y reconocimiento:
Este trabajo recibió apoyo parcial del Consejo Nacional de Ciencia y Tecnología (CONACyT) de México; proyecto Nº 53617, otorgado a GB.
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