NUEVOS MARCADORES MICROBIOLOGICOS DE LA HEPATITIS C

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Revisión de las nuevas técnicas microbiológicas desarrolladas para mejorar el diagnóstico y el tratamiento de la hepatitis C.
rodriguezdiaz9.jpg Autor:
Juan carlos Rodríguez díaz
Columnista Experto de SIIC

Institución:
Sección de Microbiología, Hospital General Universitario de Elche


Artículos publicados por Juan carlos Rodríguez díaz
Coautores
Montserrat Ruiz García* Gloria Royo García** 
Dr. en Medicina, Esp. en Microbiología, Sección de Microbiología, Hospital General Universitario de Elche, Elche, España*
Dr. en Farmacia, esp. en Microbiología, Sección de Microbiología, Hospital General Universitario de Elche, Elche, España**
Recepción del artículo
17 de Marzo, 2006
Aprobación
28 de Marzo, 2006
Primera edición
25 de Julio, 2006
Segunda edición, ampliada y corregida
7 de Junio, 2021

Resumen
La hepatitis C es un importante problema de salud pública, ya que afecta al 2% de la población mundial. Las nuevas técnicas microbiológicas basadas en la biología molecular proporcionan herramientas muy útiles para mejorar el diagnóstico, la prevención y el tratamiento de esta enfermedad. En esta revisión se exponen los últimos avances de estas técnicas, haciendo hincapié en la importancia de la genotipificación de las cuasiespecies virales y de la detección viral mediante la búsqueda del antígeno del core y del ARN viral, así como en la utilidad de la secuenciación en la detección de resistencia a fármacos y en el estudio de la epidemiología del virus.

Palabras clave
hepatitis C, diagnóstico, técnicas moleculares, secuenciación


Artículo completo

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Extensión:  +/-5.19 páginas impresas en papel A4
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Abstract
Hepatitis C is a serious public health problem because it infects 2% of world population. The new microbiological tools based on molecular biology are very useful to diagnose, prevent and treat this disease. This review shows the progress in these technologies, focusing in the importance of genotypes and viral quasispecies, as well as in the importance of the study of Ag of core and RNA detection. It also deals with the utility of the secuenciation in drugs resistance detection and virus epidemiology.

Key words
hepatitis C, diagnosis, molecular tools, secuenciation


Clasificación en siicsalud
Artículos originales > Expertos de Iberoamérica >
página   www.siicsalud.com/des/expertocompleto.php/

Especialidades
Principal: Infectología
Relacionadas: Bioquímica, Diagnóstico por Laboratorio, Gastroenterología, Medicina Interna



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Enviar correspondencia a:
Juan C. Rodríguez Díaz, Hospital General Universitario de Elche, 03203, Camí de l'Almàssera 11, Elche, España
Bibliografía del artículo
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