Crónicas de autores

Kenia Melissa Borghetti *

Autora invitada por SIIC

Protocolo de avaliação anatomopatológica do linfonodo sentinela que inclue cortes semiseriados

ALTA ACURÁCIA NA DETECÇÃO DE MICROMETÁSTASES DE CARCINOMA DE MAMA EM LINFONODO SENTINELA

A análise histológica do linfonodo sentinela através de um protocolo de cortes semi-seriados em dois níveis corados pelo HE e pela técnica da IHC utilizando anticorpos anticitoqueratina apresenta alta acurácia em predizer o status linfonodal em câncer de mama. A aplicação desta metodologia aumenta a taxa de detecção de micrometástases em relação a análise histológica de rotina de todos linfonodos axilares.

*Kenia Melissa Borghetti
describe para SIIC los aspectos relevantes de su trabajo
A HIGH ACCURATE, ANATOMICAL- PATHOLOGICAL PROTOCOL FOR THE DETECTION OF BREAST CARCINOMA MICROMETASTASIS IN SENTINEL LYMPH NODES
Revista da Sociedade Brasileira de Cancerologia,
7(28):105-113, 2004

Esta revista, clasificada por SIIC Data Bases, integra el acervo bibliográfico
de la Biblioteca Biomédica (BB) SIIC.

Institución principal de la investigación
*Programa de Post Graduados en Patología Gral. y Experimental de la Fundación de la Facultad Federal de Ciencias Médicas de Porto Alegre, Porto Alegre, Brasil
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Referencias bibliográficas
1. Czerniecki BJ, Scheff AM, Callans LS et al. Immunohistochemistry with pancytokeratins improves the sensitivity of sentinel lymph node biopsy in patients with breast carcinoma. Cancer 85(5):1098-1103, 1999.
2. Dowlatshahi K, Fan M, Bloom KJ et al. Occult metastases in the sentinel lymph nodes of patients with early stage breast carcinoma. A preliminary study. Cancer 86(6):990-996, sep. 1999.
3. Turner RR, Ollila DW, Stern S et al. Optimal histopathologic examination of the sentinel lymph node for breast carcinoma staging. The American Journal of Surgical Pathology 23(3):263-267, 1999.
4. Van Diest PJ. Histopathological workup of sentinel lymph nodes: how much is enough? Journal of Clinical Pathology 52:871-873, 1999.
5. Canavese G, Gipponi M, Catturich A et al. Technical issues and pathologic implications of sentinel lymph node biopsy in early-stage breast cancer patients. Journal of Surgical Oncology 77:81-87, 2001.
6. Jannink I, Fan M, Nagy S et al. Serial sectioning of sentinel nodes in patients with breast cancer: a pilot study. Annals of Surgery Oncology 5:310-314, 1998.
7. Mcintosh SA, Going JJ, Soukop M et al. Therapeutic implications of sentinel lymph node in breast cancer. The Lancet 354:570, ago 1999.
8. Liu LH, Siziopikou KP, Gabram S et al. Evaluation of axillary sentinel lymph node biopsy by immunohistochemistry and multilevel sectioning in patients with breast carcinoma. Archives of Pathology & Laboratory Medicine 124:1670-1673, nov 2000.
9. Sabel MS, Zhang P, Barnwell JM et al. Accuracy of sentinel node biopsy in predicting nodal status in patients with breast carcinoma. Journal of Surgery Oncology 77(4):243-246, 2001.
10. Weerts JM, Maweja S, Tamigneaux I et al. The sentinel lymph node biopsy in breast cancer. Acta Chir Belg 102(2):110-113, 2002.
11. Hsueh EC, Hansen N, Giuliano AE. Intraoperative lymphatic mapping and sentinel lymph node dissection in breast cancer. CA – A Cancer Journal for Clinicians, 50(5):279-291, sep-oct 2000.
12. Mann GB, Buchanan M, Collins JP et al. High incidence of micrometastases in breast cancer sentinel nodes. Australian New Zealand Journal of Surgery 70(11):786-790, nov. 2000.
13. Motomura K, Komoike Y, Inaji H et al. Multiple sectioning and immunohistochemical staining of sentinel nodes in patients with breast cancer. British Journal of Surgery 89:1032-1034, 2002.
14. Torrenga H, Rahusen FD, Meijer S et al. Sentinel node investigation in breast cancer: detailed analysis of the yield from step sectioning and immunohistochemistry. Journal of Clinical Pathology 54:550-552, 2001.
15. Singletary E, Allred C, Ashley P et al. Revision of the American Joint Committee on Cancer staging system for breast cancer. Journal of Clinical Oncology 20(17):3628-3636, sep 2002.
16. College of American Pathologists Consensus Statement 1999. Prognostic factors in breast cancer. Archives of Pathology & Laboratory Medicine 124(7):966-978, jul. 2000.
17. Treseler PA, Tauchi PS. Pathologic analysis of sentinel lymph node. Surgical Clinics of North America 80(6):1695-719, dec. 2000.
18. Weaver DL, Krag DN, Ashikaga T et al. Pathologic analysis of sentinel and nonsentinel lymph nodes in breast carcinoma. A multicenter study. Cancer 88(5):1099-1107, mar. 2000.
19. Mokbel K, Kirkpatrick KL. Recent advances in breast cancer. Curr Med Res Opin 18(1):26-29, 2002.
20. Cserni G, Amendoeira I, Apostolikas N et.al. Discrepancies in current practice of pathological evaluation of sentinel lymph nodes in breast cancer. Results of a questionnaire based survey by the European Working Group for Breast Screening Pathology. J. Clin. Pathol. 2004; 57(7):695-701.
Otros artículos de Kenia Melissa Borghetti

Borghetti KM, Caleffi M. O Fim de um mito: Gravidez após cancer de mama- Revista Brasileira de Mastologia, 1999, 9(4):167-172.

Caleffi, M, Borghetti KM, Gravidez após câncer de mama. In: Santos Jr LA. A mama no ciclo gravídico-puerperal. São Paulo, Editora Atheneu, 2000.

Borghetti KM, Barbosa F, Caleffi M. Biópsia do linfonodo sentinela: uma alternativa para a linfadenectomia? Revista Brasileira de Mastologia 2000, 10(3);148-155.

Caleffi M, Borghetti KM, Duarte Filho D. Dificuldades na avaliação da resposta ao tratamento quimioterápico neoadjuvante. A ressonância magnética é uma alternativa? Revista Pesquisa Médica. FFFCMPA, 2000, 34(1):64.

Caleffi M, Borghetti KM, Antoniazzi R, Graudenz M, Duarte Filho D. Preliminary report of ultrasound-guided cryoablation of breast tumors using a 2.4 mm probe. Breast Cancer Research and Treatment. 23rd Annual San Antonio Breast Cancer Symposium 2000, 64(1):103.

Caleffi M, Luzzato R, Muller APC, Borghetti KM. Fibroadenopapiloma. Mastologia News, Edição Especial XII Congresso Brasileiro de Mastologia e I Congresso de Onco-Mastologia, 2001, 3:35.

Caleffi M, Borghetti KM, Doncatto L, Muller APWC, Duarte RA, Saffer PL. Incidência de recidiva locorregional de câncer de mama após mastectomia e reconstrução mamária imediata com retalho miocutâneo (TRAM). Mastologia News - Edição Especial XII Congresso Brasileiro de Mastologia e I Congresso de Onco-Mastologia, 2001, 3:49.

Duarte Filho D, Graudenz MS, Luzzatto R, Caleffi M, Borghetti K, Dirbas FM, Nowels KW. Pilot study of a novel 10-gauge cryo-based rotational core biopsy system. Breast Cancer Research and Treatment, 24 th Annual San Antonio Breast Cancer Symposium, 2001, 69(3):222.

Caleffi M, Duarte Filho D, Borghetti K, Littrup PJ, White MT, Bouwman D, Freeman-Gibb LA, Zannis VJ, Schultz MJ. Ultrasound-guided cryoablation of breast fibroadenomas at four institutions using a 2.4 mm probe: 6-12 month follow-up. Breast Cancer Research and Treatment, 24th Annual San Antonio Breast Cancer Symposium, 2001, 69(3):228.

Caleffi M, Borghetti KM, Eschiletti J, Antoniazzi R, Duarte Filho D, Luzzato R, Graudenz MS. Misleading residual breast lesions secondary to cryosurgery: results at two years follow-up. Breast Cancer Research and Treatment, 25th Annual San Antonio Breast Cancer Symposium 2002, 76, Suppl 1:S94.

Para comunicarse con Kenia Melissa Borghetti mencionar a SIIC como referencia:
keniamb@terra.com.br

Autora invitada
18 de mayo, 2005
Descripción aprobada
3 de octubre, 2005
Reedición siicsalud
7 de junio, 2021

Acerca del trabajo completo
ALTA ACURÁCIA NA DETECÇÃO DE MICROMETÁSTASES DE CARCINOMA DE MAMA EM LINFONODO SENTINELA

Título original en castellano
UM PROTOCOLO ANATOMO-PATOLOGICO DE ALTA ACURACIA NA DETECÇÃO DE MICROMETASTASES DE CARCINOMA DE MAMA EM LINFONODO SENTINELA

Autor
Kenia Melissa Borghetti1
1 Médica, Fundação Faculdade Federal de Ciências Médicas de Porto Alegre, Mestre em Patologia Experimental

Acceso a la fuente original
Revista da Sociedade Brasileira de Cancerologia
http://www.rsbcancer.com.br

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