Diego F. Dávila *

Autor invitado por SIIC

Se propone una explicación para las alteraciones del control parasimpático de la frecuencia cardiaca de los pacientes chagásicos

ALTERACIONES DEL CONTROL PARASIMPATICO DE LA FRECUENCIA CARDIACA EN LA ENFERMEDAD DE CHAGAS CRONICA

Las alteraciones del control parasimpático de la frecuencia cardíaca en la enfermedad cardíaca chagásica crónica son consideradas primarias y específicas. Sin embargo, el control parasimpático de la frecuencia cardíaca puede ser normal o anormal, de acuerdo con la presencia y extensión del daño miocárdico. En el presente trabajo se propone una explicación común para estos contradictorios e incongruentes hallazgos.

*Diego F. Dávila
describe para SIIC los aspectos relevantes de su trabajo
VAGAL DYSFUNCTION AND THE PATHOGENESIS OF CHRONIC CHAGAS DISEASE
Institución principal de la investigación
*Universidad de los Andes, Los Andes Mérida, Venezuela
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Referencias bibliográficas
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8. Dávila DF, Santiago JJ, Odreman WA. Vagal dysfunction and the pathogenesis of chronic Chagas' disease. Int J Cardiol 2005:100:337-339.
9. Davila DF, Donis JH, Torres A, Gotteberg CF, Rossell O. Cardiacparasympathetic innervation in Chagas' heart disease. Medical Hypothesis 1991; 35:80-84.
10. Dávila DF, Inglessis G, Mazzei de Davila CA. Chagas' disease and the autonomic nervous system. Int J Cardiol 1998; 66:123-127.
11. Davila DF, Donis JH, Torres A, Ferrer J. A modified neurogenic hypothesis can explain the natural history of chronic Chagas' heart disease. Int J Cardiol 2004; 96:191-195.
12. Davila DF, Rossell O, Arata de Bellabarba G. Patogenesis of chronic chagas heart disease: parasite persistence and autoimmune responses versus cardiac remodeling and neurohormonal activation. Int J Parasitol 2002; 32:107-109.
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Otros artículos de Diego F. Dávila

Dávila DF, Santiago JJ, Odreman WA. Vagal dysfunction and the pathogenesis of chronic Chagas' disease. Int J Cardiol 2005, 100:337-339.

Dávila DF, Donis JH, Torres A, Gotteberg CF, Rossell O. Cardiacparasympathetic innervation in Chagas' heart disease. Medical Hypothesis 1991, 35:80-84.

Dávila DF, Inglessis G, Mazzei de Dávila CA. Chagas' disease and the autonomic nervous system. Int J Cardiol 1998, 66: 123-127.

Dávila DF, Donis JH, Torres A, Ferrer J. A modified neurogenic hypothesis can explain the natural history of chronic chagas heart disease. Int J Cardiol 2004; 96:191-195.

Dávila DF, Rossell O, Arata de Bellabarba G. Patogénesis of chronic chagas heart disease: parasite persistence and autoimmune responses versus cardiac remodeling and neurohormonal activation. Int J Parasitol 2002; 32:107-109.

Casado J, Dávila DF, Donis JH, Torres A, Payares A, Colmenares R et al. Electrocardiographic abnormalities and left ventricular systolic function in Chagas' heart disease. Int J Cardiol 1990; 27:55-62.

Khoury AM, Dávila DF, Bellabarba G, Donis JH, Torres A, Lemorvan C, Hernández L, Bishop W. Acute effects of digitalis and enalapril on the neurohormonal profile of chagasic patients with severe congestive heart failure. International Journal of Cardiology 57:21,1996.

Dávila DF, Donis JH, Bellabarba G, Torres A, Casado J, Mazzei de Dávila C. Cardiac afferents and neurohormonal activation in congestive heart failure. Medical Hypothesis 54:242, 2000.

Dávila DF, Bellabarba G, Donis JH, Torres A, Rossell O, Figueroa O, Amaro M, Vásquez CJ. Cardiac autonomic control mechanisms in Chagas' heart disease: Therapeutic implications Medical Hypothesis 40:33-37, 1993.

Dávila DF, Bellabarba G, Hernández L, Calmon G, Torres A, Donis JH, Barboza JS, Lemorvan C, González JC. Plasma norepinephrine, myocardial damage and left ventricular systolic function. International Journal of Cardiology 52:145-151, 1995.

Dávila DF, Angel F, Bellabarba G, Donis JH. Effects of metoprolol in chagasic patients with severe congestive heart failure. International Journal of Cardiology. 85(2-3):255-258, 2002.

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ALTERACIONES DEL CONTROL PARASIMPATICO DE LA FRECUENCIA CARDIACA EN LA ENFERMEDAD DE CHAGAS CRONICA

Título original en castellano
DisautonomIa vagal en la patogEnesis de la enfermedad de Chagas crOnica

Autor
Diego F. Dávila¹
1 Médico Cirujano, Instituto de Investigaciones Cardiovasculares, Profesor Titular

Acceso a la fuente original
International Journal of Cardiology
http://www.ijc.elsevier.com

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