Francisco J. Blanco *

Autor invitado por SIIC

El trabajo demuestra que la función mitocondrial del condrocito es importante para conseguir un cartílago íntegro

EFECTO DEL OXIDO NITRICO SOBRE LA MITOCONDRIA DEL CONDROCITO

Este estudio sugiere que el efecto del NO en la supervivencia de los condrocitos es mediado por su efecto en el complejo IV de la cadena respiratoria mitocondrial.

*Francisco J. Blanco
describe para SIIC los aspectos relevantes de su trabajo
EFFECT OF NITRIC OXIDE ON MITOCHONDRIAL RESPIRATORY ACTIVITY OF HUMAN ARTICULAR CHONDROCYTES
Institución principal de la investigación
*Complexo Hospitalario Universitario Juan Canalejo, A Coruña, España, A Coruña, España
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Referencias bibliográficas
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Otros artículos de Francisco J. Blanco

Maneiro E, López Armada MJ, Fernández Sueiro JL, Lema B, Galdo F, Blanco FJ. Aceclofenac increases the synthesis of interleukin 1 receptor antagonist and decreases the production of nitric oxide in human articular chondrocytes. J of Rheumatology 28:2692-2699.
Pablos JL, Santiago B, Galindo M, Torres C, Brehmer MT, Blanco FJ, García Lázaro FJ. Synoviocyte-derived CXCL12 is displayed on endothelium and induces angiogenesis in rheumatoid arthritis. J Immunology 170:2147-52.
Maneiro E, Martín MA, De Andrés MC, López Armada MJ, Fernández Sueiro JL, Del Hoyo P, Galdo F, Arenas J, Blanco FJ. Mitochondrial respiratory activity is altered in OA human articular chondrocytes. Arthritis & Rheumatism 48(3):700-708.
Maneiro E, De Andrés MC, Fernández Sueiro JL, Galdo F, Blanco FJ. The biological action of hyaluronan on human articular chondrocytes: The importance of molecular weight. Clinical and Experimental Rheumatology 22:307-312.
Ramallal M, Maneiro E, López Peláez E, Fuentes I, López Armada MJ, Fernández Sueiro JL, Galdo F, De Toro FJ, Blanco FJ. Xeno-implantation of pig chondrocytes into rabbit to treat localized articular cartilage defects: an animal model. Wound Repair and Regeneration 12(3):337-345.
Fuentes Boquete I, López Armada MJ, Manerio E, Fernández Sueiro JL, Caramés B, Galdo F, De Toro FJ, Blanco FJ. Pig chondrocytes xenoimplants for human chondral defects repair: an in vitro model. Wound Repair and Regeneration 12 (4):444-452.
Fernández Sueiro JL, Alonso C, Blanco FJ, Rodríguez Gómez M, Galdo F, González Gay MA. Prevalence of HLA-B27 and subtypes of HLA-B27 associated with ankylosing spondylitis in Galicia, Spain. Clinical and Experimental Rheumatology 22:465-468.
Blanco García FJ, López Armada MJ, Maneiro E. Mitochondrial dysfunction in osteoarthritis. Mitochondrion 4(5-6):715-728.

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EFECTO DEL OXIDO NITRICO SOBRE LA MITOCONDRIA DEL CONDROCITO

Título original en castellano
Efecto del Oxido Nitrico sobre la actividad respiratoria mitocondrial de los condrocitos articulares humanos

Autor
Francisco J. Blanco¹
1 Médico, Complexo Hospitalario Universitario Juan Canalejo, C

Acceso a la fuente original
Annals of the Rheumatic Diseases
http://ard.bmjjournals.com/

El artículo se relaciona estrictamente con las especialidades de siicsalud
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