Carlos Alberto Escalante Gómez *

Autor invitado por SIIC

Este es el primer estudio publicado que realmente analiza todo el perfil oxidativo de la mujer menopaúsica y el efecto que tiene en ella la TRH. Es la primera que estudia el efecto de la TRH en la oxiadaciòn del ADN in vivo.

EL USO DE LA TRH DISMINUYE LA OXIDACIÓN LIPÍDICA Y DE ADN EN MUJERES POSMENOPÁUSICAS

La etapa posmenopaúsica de la mujer se asocia con un perfil oxidativo desfavorable. En este estudio concluimos que la terapia de reemplazo hormonal no tiene ningún efecto nocivo sobre el perfil oxidativo y más bien disminuye la oxidación del ADN y de los lípidos, lo cual puede tener efecto en la salud cardiovascular y el proceso de envejecimiento en sí.

*Carlos Alberto Escalante Gómez
describe para SIIC los aspectos relevantes de su trabajo
HRT DECREASES DNA AND LIPID OXIDATION IN POSTMENOPAUSAL WOMEN
Institución principal de la investigación
*Departamento Ginecología, Hospital San Juan de Dios. Universidad de Costa Rica, San Jose, Costa Rica
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Otros artículos de Carlos Alberto Escalante Gómez

• Escalante C., Zeledón F., Ultae, G. Proteinuria: fisiología y fisiopatología aplicada. Acta Médica Costarricense. 2007; 49 (2):83-89. ISSN 0001-6002
• García M., Escalante C., Díaz C. Antipyretic effect of the aqueous extract obtained from leaves of Neurolaena lobata (Asteraceae) on a pyretic model induced by brewer’s yeast. Revista Médica de la Universidad de Costa Rica. 2007 Vol 01: 01. ISSN: 1659-2441
• Escalante, C. Jiménez, J. Anemia de Fanconi y embarazo: una combinación inusual. Acta Médica Costarricense. 2008; 50 (2):112-113.ISSN 0001-6002.
• Zeledón F., Escalante C., Morales O., Méndez E. Uso de Células Madres en la terapéutica de las enfermedades cardiovasculares desde la ciencia básica a la aplicación clínica. Parte 1: Conceptos básicos. Revista Médica de Costa Rica y Centroamérica. 2008; 584: 210-217. ISSN 0034-9909
• Zeledón F., Escalante C., Morales O., Méndez E. Uso de Células Madres en la terapéutica de las enfermedades cardiovasculares desde la ciencia básica a la aplicación clínica. Parte 2: Interés Inmunológico de las células madre Mesenquimatosas. Revista Médica de Costa Rica y Centroamérica. 2008; 584: 218-221. ISSN 0034-9909
• Zeledón F., Escalante C., Morales O., Méndez E. Uso de Células Madres en la terapéutica de las enfermedades cardiovasculares desde la ciencia básica a la aplicación clínica. Parte 3: Aplicación Clínica. Revista Médica de Costa Rica y Centroamérica. 2008; 584: 222-228. ISSN 0034-9909
• Escalante C., Mora S., Zeledón F. Perfil Oxidativo de la mujer menopáusica: Papel de los estrógenos en la prevención y tratamiento de las enfermedades. Acta Médica Costarricense. 2009; 51(4): 206-212.
• Zeledón, F. Mendez, E. Pucci, J. Escalante, C. Estrada, C. Choque cardiogénico: Historia, fisiopatología e implicaciones terapeúticas. Parte I. Rev. costarric. cardiol, Dic 2009, vol.11, no.2, p.24-32. ISSN 1409-4142
• Zeledón, F. Mendez, E. Pucci, J. Escalante, C. Estrada, C. Choque cardiogénico: Historia, fisiopatología e implicaciones terapeúticas. Parte II.Rev. costarric. cardiol, Dic 2010, vol.12, no.1-2, p.23-32. ISSN 1409-4142

Para comunicarse con Carlos Alberto Escalante Gómez mencionar a SIIC como referencia:
dr.escalante@gmail.com

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Acerca del trabajo completo

EL USO DE LA TRH DISMINUYE LA OXIDACIÓN LIPÍDICA Y DE ADN EN MUJERES POSMENOPÁUSICAS

Título original en castellano
TERAPIA DE REEMPLAZO HORMONAL DISMINUYE LA OXIDACION LIPIDICA Y DE ADN EN MUJERS POSTMENOPAUSICAS

Autores
Carlos Alberto Escalante Gómez¹, Silvia Quesada Mora²
1 Médico, Departamento Ginecología, Hospital San Juan de Dios. Universidad de Costa Rica, San Jose, Costa Rica, Médico Especialista Consultor / Profesor
2 Microbióloga, Universidad de Costa Rica, Jefe del Departamento de Bioquímica - Fa

Acceso a la fuente original
Climacteric
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