Carmen Rodriguez-Avial *

Autora invitada por SIIC

Ejemplo preocupante de la imposibilidad de erradicar una infección y sus consecuencias.

KLEBSIELLA PNEUMONIAE, PRODUCTORA DE (BLEE), PRESENTA “IN VIVO” RESISTENCIA A IMIPENEM Y TIGECICLINA

Desarrollo in vivo de resistencia a imipenem, por producción de VIM-1, y a tigeciclina, en Klebsiella pneumoniae, productora de BLEE, durante el tratamiento prolongado con diferentes antimicrobianos de una urosepsis en un paciente receptor de trasplante renal. Es un ejemplo preocupante de la imposibilidad de erradicar una infección y de sus consecuencias.

*Carmen Rodriguez-Avial
describe para SIIC los aspectos relevantes de su trabajo
KLEBSIELLA PNEUMONIAE: DEVELOPMENT OF A MIXED POPULATION OF CARBAPENEM AND TIGECYCLINE RESISTANCE DURING ANTIMICROBIAL THERAPY IN A KIDNEY TRANSPLANT PATIENT
Institución principal de la investigación
*Universidad Complutense de Madrid, Madrid, España
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Referencias bibliográficas
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Otros artículos de Carmen Rodriguez-Avial

Rodríguez-Avial I, Rodríguez-Avial C, Culebras E, Benítez A, Picazo JJ. Distribution of mef(A) and erm(B) genes in macrolide-resistant blood isolates of viridans group streptococci. J Antimicrob Chemotherapy 47:719-730, 2001.
González-Praetorius A, Rodríguez-Avial C, Fernández C, Pérez-Pomata MT, Gimeno C, Bisquert J. Prevalencia de hepatitis A en la provincia de Guadalajara. ¿Es España un país de baja endemia? Enferm Infecc Microbiol Clin 19:428-431, 2001.
Rodríguez-Avial C, Rodríguez-Avial I, Picazo JJ. Sensibilidad a penicilina y otros 13 antimicrobianos de estreptococo del grupo viridans resistentes a eritromicina aislados de hemocultivos. Rev Esp Quimioterap 14(3):275-280, 2001.
Rodríguez-Avial I, Rodríguez-Avial C, Picazo JJ. Actividad in vitro de seis fluoroquinolonas y penicilina frente a 101 estreptococos del grupo viridans caracterizados en su resistencia a la eritromicina. Rev Esp Quimioterap 14(4):364-368, 2001.
Rodríguez-Avial I, Rodríguez-Avial C, Culebras E, Picazo JJ. Distribution of tetracycline resistance genes tet(M), tet(O), tet(L) and tet(K) in blood isolates of viridans group streptococci harbouring mef(A) and erm(B) genes. Susceptibility to quinupristin/dalfopristin and linezolid. Int J Antimicrob Agents 21:536-541, 2003.
Rodríguez-Avial I, Rodríguez-Avial C, Culebras E, Picazo JJ. In vitro activity of Telithromycin against viridans group streptococci and Streptococcus bovis isolated from blood: Antimicrobial susceptibility patterns in different group of species. Antimicrob Agents Chemother 49:820-823, 2005.
Rodriguez-Avial I, Rodríguez-Avial C, López O, Picazo JJ. Trends in nalidixico acid resistance in nontyphoidal Salmonella isolated from 1999 to 2002: decreased susceptibility to 6 fluoroquinolones. Diagnostic Microbiology and Infectious Diseases 52:261-264, 2005.
Rodríguez-Avial I, Rodríguez-Avial C, López O, Culebras E, Picazo JJ. In vitro activity of tigecycline (GAR-936) and other antimicrobials against tetracycline-and ciprofloxacin resistant Campylobacter clinical isolates. International Journal of Antimicrobial Agents 27:303-306, 2006.
Ríos E, Rodríguez-Avial I, Rodríguez-Avial C, Hernández E, Picazo JJ. High percentage of resistance to ciprofloxacin and qnrB19 gene identified in urinary isolates of extended-spectrum betalactamase-producing Escherichia coli in Madrid, Spain. Diagnostic Microbiology and Infectious Diseases 67:380-383, 2010.

Para comunicarse con Carmen Rodriguez-Avial mencionar a SIIC como referencia:
cravial@med.ucm.es

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Acerca del trabajo completo

KLEBSIELLA PNEUMONIAE, PRODUCTORA DE (BLEE), PRESENTA “IN VIVO” RESISTENCIA A IMIPENEM Y TIGECICLINA

Título original en castellano
KLEBSIELLA PNEUMONIAE: DESARROLLO DE UNA POBLACION MIXTA, RESISTENTE A CARBAPENEMICOS Y TIGECICLINA, EN UN PACIENTE TRANSPLANTADO DE RIÑON , A LO LARGO DE SU TRATAMIENTO CON ANTIMICROBIANOS.

Autores
Carmen Rodriguez-Avial¹, Iciar Rodriguez-Avial², Paloma Merino³, Juan J. Picazo⁴
1 Profesora Titular de Microbiol, Universidad Complutense de Madrid, Madrid, España, Profesora Titular
2 Dra Ciencias Biológicas, Hospital Clínico San Carlos, Facultativo Titulado Superior
3 Dra Medicina, Hospital Clínico San Carlos, Adjunto
4 Dr Medicina, Universidad Complutense/ Hospital Clínico San Carlos, Catedrático/ Jefe de Servicio

Acceso a la fuente original
Clinical Microbiology and Infection
http://www.blackwellpublishing.com/journal.asp?ref=1198-743X&site=1

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