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José M. Olmos Martínez *

Autor invitado por SIIC

El trabajo se ha llevado a cabo en un elevado número de pacientes atendidas en un Centro de Atención Primaria.

MASA OSEA Y MARCADORES DE LA REMODELACION EN MUJERES HIPERTENSAS TRATADAS CON TIAZIDAS

Las mujeres hipertensas tratadas con tiazidas presentan un aumento en la densidad mineral ósea y una disminución en los marcadores de remodelación que podría contribuir a explicar el efecto protector que parecen ejercer estos fármacos sobre la osteoporosis.

*José M. Olmos Martínez
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BONE TURNOVER MARKERS AND BONE MINERAL DENSITY IN HYPERTENSIVE POSTMENOPAUSAL WOMEN ON TREATMENT
Maturitas,
65(4):396-402 Abr, 2010

Esta revista, clasificada por SIIC Data Bases, integra el acervo bibliográfico
de la Biblioteca Biomédica (BB) SIIC.

Institución principal de la investigación
*Universidad de Cantabria, Santander, España
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Referencias bibliográficas
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Osteoporos Int 18:479-486, 2007. Cappuccio FP, Meihlan E, Zmuda JM, Cauley JA. High blood pressure and bone mineral loss in elderly white women: a prospective study. Lancet 354:971-975, 1999. Cauley JA, Cummings SR, Seeley DG, Black D, Browner W, Kuller LH, et al. Effects of thiazide diuretic therapy on bone mass, fractures, and falls. The study of Osteoporotic Fractures Research Group. Ann Intern Med 118:666-673, 1993. Díez A, González-Macías J, Marín F, Abizanda M, Alvarez R, Gimeno A, et al., for the ECOSAP study investigators. Prediction of absolute risk of non-spinal fractures using clinical risk factors and heel quantitative ultrasound. Osteoporos Int 18:629-639, 2007. Feskanisch D, Willet WC, Stampfer JM, Golditz GA. A prospective study of thiazide use and fractures in women. Osteoporos Int 7:79-84, 1997. Garnero P, Borel O, Delmas PD. Evaluation of a fully automated serum assay for C-terminal cross-linking telopeptide of type I collagen in osteoporosis. Clin Chem 47:694-702, 2001. Garnero P, Vergnaud P, Hoyle N. Evaluation of a fully automated serum assay for total N-terminal propeptide of type I collagen in postmenopausal osteoporosis. Clin Chem 54:188-196, 2008. Hanley DA, Brown JP, Tenenhause A, Olszynski WP, Toannidis G, Berger C, et al. Associations between disease conditions, bone mineral density, and prevalent vertebral deformities in men and women 50 years of age and older: cross-sectional results of the Canadian Multicentre Osteoporosis Study. J Bone Miner Res 18:784-790, 2003. Kamel HK. Low-dose thiazide and bone density. Lancet 136:252-253, 2002. La Croix AZ, Wienpahl J, White LR, et al. Thiazide diuretic agents and the incidence of hip fracture. N Engl J Med 322:286-290, 1990. LaCroix AZ, Ott SM, Ichikawa L, Scholes D, Barlow WE. Low-dose hydroclorothiazide and preservation of bone mineral density in older adults. A randomized, double-blind, placebo-controlled trial. Ann Intern Med 133:516-526, 2000. Lajeunesse D, Menard P, Morceau R, Hamel L. Direct effects of thiazides on the human osteosarcoma cell line MG-63. J Bone Miner Res 9:S355, 1994. Lalande A, Roux S, Denne MA, Stanley ER, Schiavi P, Guez D, et al. Indapamide, a thiazide diuretic decrease bone resorption in vitro. J Bone Miner Res 16:361-370, 2001. Lemann JJ, Gray RW, Malerhofer WJ, Cheung HS. Hydrochlorothiazide inhibits bone resorption in men despite experimentally elevated serum 1,25-dihydroxyvitamin D concentrations. Kidney Int 28:951-958, 1985. Melton LJ III, Chrischilles EA, Cooper C, Lane AW, Riggs BL. How many women have osteoporosis? J Bone Miner Res 7:1005-1010, 1992. Middler S, Pack CY, Murad F, Bartter FC. Thiazide diuretics and calcium metabolism. Metabolism 22:139-146, 1973. Mussolino ME, Gillum RF. Bone mineral density and hypertension prevalence in postmenopausal women: results from the Third National Health and Nutrition Examination Survey. Ann Epidemiol 16:395-399, 2006. Nowack R, Hofner MC, Reichel H, Schmidt Gayk H, Ritz E. Subacute effects of thiazide administration on renal hemodynamics and calcium metabolism. Clin Invest 70:689-691, 1992. Ott SM, La Croix AZ, Scholles D, Ichikawa LE, Wu K. Effects of three years of low-dose thiazides on mineral metabolism in healthy elderly prsons. Osteoporos Int 19:1315-1322, 2008. Peh CA, Horowitz M, Wishart JM, Need AG, Morris HA, Nordin BE. The effect of chlorothiazide on bone-related biochemical variables in normal postmenopausal women. J Am Geriatr Soc 41:513-516, 1993. Pérez Castrillón JL, Justo I, Silva J, Sanz A, Igea R, Escudero P, et al. Bone mass and bone modelling markers in hypertensive postmenopausal women. J Hum Hypertens 17:107-110, 2003. Pérez-Castrillón JL, Justo I, Sanz-Cantalapiedra A, Pueyo C, Hernández G, Dueñas A. Effect of the antihypertensive treatment on the bone mineral density and osteoporotic fracture. Current Hypertension Rev 1:61-66, 2005. Pierce WM, Nardin GF, Fuqua MF, Sabah-Maren E, Stern SH. Effect of chronic carbonic anhydrase inhibitor therapy on bone mineral density in white women. J Bone Miner Res 6:347-354, 1991. Reid IR, Ames RW, Orr-Walker BJ, Clearwater JM, Horne AM, Evans MC, et al. Hydrochlorothiazide reduces loss of cortical bone in normal postmenopausal women: a randomized controlled trial. Am J Med 109:362-370, 2000. Rejnmark L, Vestergaard P, Heickendorff L, Adreansen F, Mosekilde L. Effects of thiazide- and loop-diuretics, alone or in combination, on calciotropic hormmones and biochemical bone markers: a randomized controlled study. J Intern Med 250:144-153, 2001. Renjmark L, Vestergaard P, Mosekilde L. Reduced fracture risk in users of thiazide diuretics. Calcif Tissue Int 76:167-175, 2005. Reusz GS, Dobos M, Vasarhely B, Sallay P, Szabo A, Horvath C, et al. Sodium transport and bone mineral density in hypercalciuria with thiazide treatment. Pediatr Nephrol 12:30-34, 1998. Riancho JA, Valero C, Hernández JL, Olmos JM, Paule B, Zarrabeitia A, González-Macías J. Biomechanical indices of the femoral neck estimated from the Standard DXA output: Age- and sex-related differences. J Clin Densitomet 10:39-45, 2007. Schoofs MW, van der Klift M, Hofman A, de Laet CE, Herings RM, Stijnen T, et al. Thiazide diuretics and the risk for hip fracture. Ann Intern Med 139:476-482, 2000. Sigurdson G, Franzson L. Incrased bone mineral density in a population-based group of 70-year-old women on thiazide diuretics, independent of parathyroid hormone levels. J Intern Med 250:51-56, 2001. Sosa M, Saavedra P, Muñoz M, Alegre J, Gómez C, González Macías J, et al., and the GIUMO Study Group. Quantitative ultrasound calcaneus measurements: normative data and precision in the Spanish population. Osteoporos Int 13:487-492, 2002. Steiniche T, Mosekilde L, Christensen MS, Melsen F. Histomorphometric analysis of bone in idiopatic hypercalciuria before and after treatment with thiazides. APMIS 97:302-308, 1989. Sun J, Elwood W, Barnes PJ, Chung KF. Effect of thiazide diuretics against neurally mediated contraction of guinea pig airways: contribution of carbonic anhydrase. Am Rev Respir Dis 148:902-908, 1993. Transbol I, Christensen M,S, Jensen GF, Christiansen C, McNair P. Thiazide for the postponement of postmenopausal bone loss. Metabolism 31:383-386, 1982. Tsuda K, Nistui I, Masuyama Y. Bone mineral density in women with essential hypertension. Am J Hypertens 14:704-707, 2001. van Daele PL, Burguer H, Algra D, Hofman A, Grobbee DE, Birkenhager JC, Pols HA. Age-associated changes in ultrasound measurements of the calcaneus in men and women: the Rotterdam study. J Bone Miner Res 9:1751-1757, 1994. Wasnick RD, Davis J, Ross P, Vogel J. Effect of thiazide on rates of bone mineral loss: a longitudinal study. Br Med J 301:1303-1305, 1990. Wasnick RD, Davis JW, He YF, Petrovic H, Ross PD. A randomized, double-masked, placebo-controlled trial of chlortalidone and bone loss in elderly women. Osteoporos Int 5:247-251, 1995. WHO study group. Assessment of fracture risk and its application to screening for postmenopausal osteoporosis. Technical report series 843. Geneva: WHO, 1994. Yamamoto M, Yamaguchi T, Yamauchi M, Yano S, Sugimoto T. Serum pentosidine levels are positively associated with the presence of vertebral fractures on postmenopausal women with type 2 diabetes. J Clin Endocrinol Metab 93:1013-1019, 2008.
Otros artículos de José M. Olmos Martínez

Trend in hip fracture epidemiology over a 14-year period in a Spanish population. JL Hernández, JM Olmos, MA Alonso, CR González, J Martínez, M Pajarón, J Llorca, J González Macías. Osteoporos Int 2006; 17: 464-470. Osteoprotegerin and bone mass in patients treated of squamous cell head and neck cancer (SCHNC). C Valero, JM Olmos, F Rivera, JL Hernández, ME Vega, J González Macías. Calcif Tissue Int 2006; 78: 343-347. ¿Cómo valorar la respuesta al tratamiento de la osteoporosis?. JM Olmos, J Martínez, J González- Macías. Rev Clin Esp 2008; 208: 247-250. Polymorphism of the WNTB10 gene, bone mineral density and fractures in postmenopausal women. JL Pérez-Castrillón, JM Olmos, DN Nan, J Castillo, J Arozamena, A Montero, MI Pérez-Nuñez, JA Riancho. Calcif Tissue Int 2009; 85: 113-118. Bone turnover markers in Spanish postmenopausal women.The Camargo cohort study. J Martínez, JM Olmos, JL Hernández, G Pinedo, J Llorca, E Obregón, C Valero, J González Macías. Clin Chim Acta 2009; 409: 70-74. Serum lipids and bone metabolism in Spanish men. The Camargo Cohort study. JL Hernández, JM Olmos, C Ramos, J Martínez, J de Juan, C Valero, D Nan, J González Macías. Endocr J 2010; 57: 51-60. Time course of bone loss in patients with anorexia nervosa. JM Olmos, C Valero, A Gómez del Barrio, JA Amado, JL Hernández, J Menéndez-Arango, J González Macías. Int J Eat Dis 2009 Aug 5 (Epub ahead of print)

Para comunicarse con José M. Olmos Martínez mencionar a SIIC como referencia:
miromj@humv.es

Autor invitado
18 de mayo, 2010
Descripción aprobada
17 de julio, 2010
Reedición siicsalud
10 de septiembre, 2021

Acerca del trabajo completo
MASA OSEA Y MARCADORES DE LA REMODELACION EN MUJERES HIPERTENSAS TRATADAS CON TIAZIDAS

Título original en castellano
MASA OSEA Y MARCADORES BIOQUIMICOS DE LA REMODELACION EN MUJERES POSTMENOPAUSICAS HIPERTENSAS EN TRATAMIENTO

Autores
José M. Olmos Martínez1, Jose L. Hernández Hernández2, Josefina Martínez García3, Jesús Castillo Obeso4, Carmen Valero Díaz De Lamadrid5, Isabel Pérez Pajares6, Daniel Nan7, Jesús González Macías8
1 Médico, Hospital Universitario M. Valdecilla-ifimav, Universidad de Cantabria, Santander, España, M. Adjunto M. Interna. Prof. Asociado
2 Médico, Hospital Universitario M. Valdecilla-ifimav, Universidad de Cantabria. Santander, M. Adjunto. Prof. Asociado
3 Médico, Hospital de Laredo-ifimav, M. Adjunto
4 Médico, Centro de Salud "josé Barros", Camargo. Universidad de Cantabria., Médico Atención Primaria
5 Médico, Hospital Universitario M. Valdecilla-ifimav. Universidad de Cantabria. Santande, M. Adjunto. Prof. Asociado
6 Médico, Centro de Salud "josé Barros", Camargo., Médico de Atención Primaria
7 Médico, Hospital Universitario M. Valdecilla-ifimav. Universidad de Cantabria. Santander, M. Adjunto
8 Médico, Hospital Universitario M. Valdecilla-ifimav. Universidad de Cantabria, Santander, Jefe de Departamento. Catedrático de Med

Acceso a la fuente original
Maturitas
https://www.journals.elsevier.com/maturitas

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