Juan Andrés Orellana *

Autor invitado por SIIC

Un protocolo de hipoxia in vitro en presencia de 25 mM de glucosa incrementa la muerte astroglial durante la reoxigenación.

EL PAPEL DE LOS HEMICANALES EN LA MUERTE CELULAR DURANTE EL INFARTO CEREBRAL Y DIABETES

Los hemicanales formados por conexina 43 pueden ser un nuevo blanco terapéutico para reducir la muerte celular luego de un infarto cerebral, particularmente durante condiciones hiperglucémicas.

*Juan Andrés Orellana
describe para SIIC los aspectos relevantes de su trabajo
HYPOXIA IN HIGH GLUCOSE FOLLOWED BY REOXYGENATION IN NORMAL GLUCOSE REDUCES THE VIABILITY OF CORTICAL ASTROCYTES THROUGH INCREASED PERMEABILITY OF CONNEXIN 43 HEMICHANNELS
Institución principal de la investigación
*Pontificia Universidad Católica de Chile, Santiago, Chile
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