Alberto Ortiz *

Autor invitado por SIIC

El trabajo ilustra acerca de mecanismos moleculares y nuevas dianas terapéuticas en nefropatías

MUERTE CELULAR POR APOPTOSIS EN ENFERMEDAD RENAL

El conocimiento de los mecanismos moleculares de la muerte celular facilitará la intervención sobre nuevas dianas terapéuticas para las nefropatías.

*Alberto Ortiz
describe para SIIC los aspectos relevantes de su trabajo
MECHANISMS OF RENAL APOPTOSIS IN HEALTH AND DISEASE
Institución principal de la investigación
*Universidad Autonoma Madrid, Madrid, España
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Otros artículos de Alberto Ortiz

1. Justo P, Sanz AB, Egido J, Ortiz A. 3,4-di-deoxyglucosone-3-ene induces apoptosis in renal tubular epithelial cells. Diabetes 54:2424-9, 2005.
2. Justo P, Sanz AB, Sanchez-Niño MD, Winkles JA, Lorz C, Egido J, Ortiz A. Cytokine cooperation in renal tubular cell injury: the role of TWEAK. Kidney Int 70:1750-8, 2006.
3. Marrón B, Remón C, Pérez-Fontán M, Quirós P, Ortíz A. Benefits of preserving residual renal function in peritoneal dialysis. Kidney Int 73:S42-S51, 2008.
4. Lorz C, Benito-Martín A, Boucherot A, Ucero AC, Rastaldi MP, Henger A, Armelloni S, Santamaría B, Kretzler M, Egido J, Ortiz A. The death ligand TRAIL in diabetic nephropathy. J Am Soc Nephrol 19:904-14, 2008.
5. Sanz AB, Justo P, Sanchez-Niño MD, Blanco-Colio LM, Winkles JA, Kreztler M, Jakubowski A, Egido J, Ruiz-Ortega M, Ortiz A. The cytokine TWEAK modulates renal tubulointerstitial inflammation. J Am Soc Nephrol 19:695-703, 2008.
6. Ortiz A, Oliveira JP, Waldek S, Warnock DG, Cianciaruso B, Wanner C, on behalf of the Fabry Registry Nephropathy in males and females with Fabry disease: Cross-sectional description of patients before treatment with enzyme replacement therapy Nephrol Dial Transplant 23:1600-7, 2008.
7. Ortiz A, Oliveira JP, Wanner C, Brenner B, Waldek S, Warnock D. Diagnosis and treatment of Fabry nephropathy, with clinical practice recommendations and guidelines. Nature Clinical Practice Nephrology 4:327-36, 2008.
8. Moreno JA, Sanchez-Niño MD, Sanz AB, Lassila M, Holthofer H, Blanco-Colio LM, Egido J, Ruiz-Ortega M, Ortiz A. A slit in podocyte death. Current Medicinal Chemistry 15:1645-54, 2008.
9. Sanchez-Niño MD, Sanz AB, Ihalmo P, Lassila M, Holthofer H, Mezzano S, Aros C, Groop PH, Saleem MA, Mathieson PW, Langham R, Kretzler M, Nair V, Lemley KV, Nelson RG, Mervaala E, Mattinzoli D, Rastaldi MP, Ruiz-Ortega M, Martin-Ventura JL, Egido J, Ortiz A. The MIF receptor CD74 in diabetic podocyte injury. J Am Soc Nephrol [Epub ahead of print], 2008.
10. Carrero JJ, Ortiz A, Qureshi AR, Martín-Ventura JL, Bárány P, Heimbürger O, Marrón B, Metry G, Snaedal S, Lindholm B, Egido J, Stenvinkel P, Blanco-Colio LM. Additive effects of soluble TWEAK and inflammation on mortality in patients undergoing hemodialysis. Clin J Am Soc Nephrol 4:110-8, 2009.

Para comunicarse con Alberto Ortiz mencionar a SIIC como referencia:
aortiz@fjd.es

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Acerca del trabajo completo

MUERTE CELULAR POR APOPTOSIS EN ENFERMEDAD RENAL

Título original en castellano
MECANISMOS DE LA APOPTOSIS RENAL EN LA SALUD Y EN LA ENFERMEDAD

Autor
Alberto Ortiz¹
1 Medico, Fundacion Jimenez Diaz, Universidad Autonoma Madrid, Madrid, España, Jefe Asociado/profesor Asociado

Acceso a la fuente original
Journal of the American Society of Nephrology
http://www.JASN.org

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