PAPILOMA INVERTIDO - ¿NEOFORMAÇAO UROTELIAL BENIGNA?

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Os papilomas invertidos são neoformações raras de etiologia desconhecida. Embora considerados no passado entidades perfeitamente benignas, avoluma-se a literatura que demonstra fenómenos de recorrência, multifocalidade e associação com os carcinomas uroteliais, impondo vigilância adequada.
xambre9.jpg Autor:
Luís manuel Cardoso manso xambre
Columnista Experto de SIIC

Institución:
Hospital Pedro Hispano - ULS Matosinhos


Artículos publicados por Luís manuel Cardoso manso xambre
Coautores
Manuel Augusto Alves Cerqueira* Fernando de Jesus Silva Carreira* André Filipe Martins Figueiredo Cardoso* 
Licenciado em Medicina, Hospital Pedro Hispano - ULS Matosinhos, Matosinhos, Portugal*
Recepción del artículo
21 de Abril, 2006
Aprobación
14 de Julio, 2006
Primera edición
23 de Febrero, 2007
Segunda edición, ampliada y corregida
7 de Junio, 2021

Resumen
Os papilomas invertidos são neoformações uroteliais raras, constituindo entre 2.2% e 4.5% das neoplasias uroteliais (benignas ou malignas). Apresentam maioritariamente localização vesical, nomedadamente a nível da região trigonal, embora haja casos descritos ao longo de todo o aparelho excretor urinário. Apesar dos critérios histológicos estarem bem definidos, a sua génese é incompletamente compreendida. Considerados no passado tumores benignos, múltiplas evidências apontam para a possibilidade de recorrência e associação com carcinomas uroteliais, de forma síncrona ou metacrónica, impondo problemas no que toca ao seguimento dos doentes. Colocam problemas ao nível de diagnóstico diferencial com os carcinomas uroteliais, designadamente quando localizados no aparelho excretor alto, motivando muitas vezes atitudes cirúrgicas agressivas desnecessárias, condicionando perda de unidades renais. Os autores realizam uma revisão crítica da literatura disponível acerca da etiologia, clínica, critérios e meios de diagnóstico, tratamento e aspectos de prognóstico desta afecção.

Palabras clave
papiloma invertido, urotélio, carcinoma, oncologia, bexiga, ureter


Artículo completo

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Extensión:  +/-4.59 páginas impresas en papel A4
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Abstract
Inverted papilomas are rare urotelial neoformations, which account for 2.2% to 4.5% of urotelial neoplasms (benign or malignant). Most of them have vesical location, namely on the trigonal area, although there are cases which have been described along the whole of the urinary excretory system. In spite of the well defined histological criteria, their origin is not entirely understood. Considered as benign tumors in the past, multiple evidence points out to the possibility of recurrence and to association with urotelial carcinomas, synchronic or metachronic, thus causing problems with the patient's follow-up. The distinction between inverted papilomas and urotelial carcinomas also poses problems, especially when located in the high excretory system, very often leading to aggressive, unnecessary surgical procedures with loss of kidney units. The authors present a critical review of the available literature on the etiology, clinical presentation, diagnostic criteria, treatment and prognostic aspects of this condition.

Key words
papilloma inverted, urothelium, carcinoma, oncology, bladder, urether


Clasificación en siicsalud
Artículos originales > Expertos de Iberoamérica >
página   www.siicsalud.com/des/expertocompleto.php/

Especialidades
Principal: Urología
Relacionadas: Anatomía Patológica, Diagnóstico por Laboratorio, Oncología



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Enviar correspondencia a:
Luís M. Cardoso Manso Xambre, Hospital Pedro Hispano - ULS Matosinhos, 4490-157, Rua de Mourões, 330 - 4º Dto, Póvoa de Varzim, Portugal
Bibliografía del artículo
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