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PUESTA AL DIA DE LA TERAPIA CON CORTICOIDES INTRANASALES

(especial para SIIC © Derechos reservados)
La rinitis alérgica es una enfermedad crónica del tracto respiratorio superior; en la actualidad afecta a entre el 5% y el 40% de la población general en muchos países desarrollados.
Autor:
Duygu Keskin
Columnista Experto de SIIC

Institución:
Memorial Hospital

Artículos publicados por Duygu Keskin
Coautores
Cemal Cingi* Ibrahim Sayin** 
University of Osmangazi, Eskisehir, Turquía*
Bakirkoy Dr. Sadi Konuk Research and Training Hospital, Estambul, Turquía**
Recepción del artículo
22 de Agosto, 2012 		Aprobación
15 de Octubre, 2012
Primera edición
6 de Diciembre, 2012 		Segunda edición, ampliada y corregida
7 de Junio, 2021

PUESTA AL DIA DE LA TERAPIA CON CORTICOIDES INTRANASALES

Resumen
La rinitis alérgica (RA) es una enfermedad crónica del tracto respiratorio superior cuya prevalencia ha aumentado en las últimas décadas; en la actualidad afecta entre el 5% y 40% de la población general en muchos países desarrollados. Aunque no se asocia con morbilidad grave o mortalidad, en un número considerable de enfermos la RA afecta sustancialmente la calidad de vida. El tratamiento eficaz incluye el tratamiento de la RA y de las comorbilidades. Los corticoides intranasales (CIN) se utilizan para el tratamiento de la RA desde principios de la década de 1970. En la actualidad, los CIN se consideran los agentes más eficaces y la terapia de primera línea para aliviar los síntomas de la RA. Diversos estudios han demostrado que los CIN y, en especial, los preparados más nuevos, son fármacos seguros, asociados con efectos adversos graves mínimos o nulos. En este trabajo se realizó una actualización de la terapia con CIN.

Palabras clave
corticoides intranasales, corticoides tópicos, rinitis alérgica, seguridad, eficacia, efectos adversos, mecanismo de acción, farmacología


Artículo completo
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Update on therapy with intranasal corticosteroids

Abstract
Allergic rhinitis (AR) is a chronic upper respiratory disease, which has increased in prevalence over the last few decades and currently affects between 5% and 40% of the general population in many developed countries. Although it is not associated with severe morbidity and mortality, allergic rhinitis has a major effect on the quality of life in a large number of patients. An effective approach requires treatment of AR and its comorbidities. Intranasal corticosteroids (INS) have been used for the treatment of rhinitis since the early 1970s. Intranasal corticosteroids are now considered the most effective and first line therapy for the nasal symptoms of allergic rhinitis. Many studies have shown that INS, particularly the newer preparations are safe medications with minimal to no serious side effects. This report presents an update on intranasal corticoid therapy.

Key words
intranasal corticoids, topical corticosteroids, allergic rhinitis, safety, efficacy, side effect, mechanism of action, pharmacology


Full text
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Especialidades
Principal: Alergia, Otorrinolaringología
Relacionadas: Administración Hospitalaria, Anatomía Patológica, Atención Primaria, Bioquímica, Diagnóstico por Laboratorio, Educación Médica, Endocrinología y Metabolismo, Epidemiología, Farmacología, Genética Humana, Inmunología, Medicina Familiar, Medicina Farmacéutica, Medicina Interna, Neumonología, Oftalmología, Pediatría, Salud Pública



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Enviar correspondencia a:
Cemal Cingi, Department of Otorhinolaryngology, University of Osmangazi, 26020, Sumer Mah. Kar Sokak 10/3, Eskisehir, Turquía
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