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¿Cuál es el efecto adverso más frecuente del anastrozol?
Introducción:
El tratamiento con anastrozol durante 5 años para la prevención del cáncer de mama tendría un efecto continuo a largo plazo que se extendería más allá del período de tratamiento.
Lectura recomendada:
Use of Anastrozole for Breast Cancer Prevention (IBIS-II): Long-term Results of a Randomised Controlled Trial
The Lancet, 395(10218):117-122
Lectura recomendada:
Association Between the Implementation of Hospital-Based Palliative Care and Use of Intensive Care During Terminal Hospitalizations
JAMA Network Open, 3(1):1-13
Lectura recomendada:
Impact and Effectiveness of mRNA BNT162b2 Vaccine Against SARS-CoV-2 Infections and COVID-19 Cases, Hospitalisations, and Deaths Following a Nationwide Vaccination Campaign in Israel: an Observational Study Using National Surveillance Data
The Lancet, :1-11
Lectura recomendada:
Arterial Events, Venous Thromboembolism, Thrombocytopenia, and Bleeding after Vaccination with Oxford-AstraZeneca ChAdOx1-S in Denmark and Norway: Population Based Cohort Study
BMJ, 373(1114):1-10
Lectura recomendada:
An Endoscopic Transluminal Approach, Compared with Minimally Invasive Surgery, Reduces Complications and Costs for Patients with Necrotizing Pancreatitis
Case Reports in Gastroenterology, 156(4):1027-1040
Lectura recomendada:
EfÞcacy and Tolerability of Riluzole in Psychiatric Disorders: a Systematic Review and Preliminary Meta-analysis
Psychiatry Research, 278:294-302
Lectura recomendada:
Peficitinib, a JAK Inhibitor, in the Treatment of Moderate-to-Severe Rheumatoid Arthritis in Patients With an Inadequate Response to Methotrexate
Arthritis & Rheumatology, 69(4):709-719
Lectura recomendada:
Depressed Mood and Suicidality in Individuals Exposed to Tetrabenazine in a Large Huntington Disease Observational
Study
Journal of Huntington's disease, 2(4):509-515
Lectura recomendada:
Safety and Tolerability Profile of New Antiepileptic Drug Treatment in Children with Epilepsy
Expert Opinion on Drug Safety, 17(10):1015-1028
En relación con el tratamiento con lacosamida de la epilepsia resistente a drogas y la epilepsia refractaria, señale la opción correcta:
Introducción:
La epilepsia es una de las patologías neurológicas más frecuentes, con una incidencia anual estimada de 50/100 000 personas y una prevalencia de 700/100 000. Se ha sugerido que aproximadamente 60% de los pacientes responden a tratamientos clásicos y logran remisión, mientras que 30% a 40% de los casos son refractarios al tratamiento. La lacosamida es una droga novedosa para el tratamiento de estas enfermedades.
Lectura recomendada:
Efficacy of Lacosamide in Children and Adolescents with Drug-Resistant Epilepsy and Refractory Status Epilepticus: A Systematic Review
Seizure, 56:34-40
Lectura recomendada:
Prasugrel or Ticagrelor in Patients with Acute Coronary Syndrome and Diabetes: a Propensity Matched Substudy of RENAMI
European heart journal. Acute cardiovascular care, :1-7
Lectura recomendada:
Masitinib as an Add-on Therapy to Riluzole in Patients with Amyotrophic Lateral Sclerosis: a Randomized Clinical Trial
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, :1-10
Lectura recomendada:
Long-Term Control of Epileptic Drop Attacks with the Combination of Valproate, Lamotrigine, and a Benzodiazepine:
A ‘‘Proof of Concept,’’ Open Label Study
Epilepsia, 52(7):1303-1310