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While most of the selected texts belong to original articles,
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institución:(a) Faculty of Medicine FMUSP, University of São Paulo, São Paulo, SP, Brazil. (b) Faculty of Medicine FMUSP, University of São Paulo, São Paulo, SP, Brazil.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Effects of neuromuscular electrical stimulation during hemodialysis on muscle strength, functional capacity and postural balance in patients with end-stage renal disease: a randomized controlled trial.
Effects of neuromuscular electrical stimulation during hemodialysis on muscle strength, functional capacity and postural balance in patients with end-stage renal disease: a randomized controlled trial.
Fuente:Bmc Nephrology
Tipo de trabajo:Estudio aleatorizado y controlado
Extracto:
This study
supports the effectiveness of intradialytic NMES to improve muscular strength,
functional capacity and postural balance in HD patients. Given the limited
implementation of exercise programs in dialysis clinical practice, NMES during HD
sessions offers a novel therapeutic alternative to enhance physical condition and
quality of life in these patients. TRIAL REGISTRATION: Pan African Clinical Trial
Registry Identifer: PACTR202206634181851 Registered on 21/06/2022. Registered
trial name: Beneficial Effect of Intradialytic Electrical Muscle Stimulation in
Hemodialysis Patients.
Claves:Chronic kidney disease, Electric stimulation therapy, Hemodialysis
Cita:BMC Nephrol 2025 Feb 19; 26 (1) : 86.
Autor/es:Machfer, Amal (a) Fekih, Nadia (b)
institución:(a) Research Laboratory: Education, High Institute of Sport and Physical Education, University of Sfax, Sport et Santé, EM2S, LR19JS01, Motricité, Tunisia. (b) Research Laboratory: Education, High Institute of Sport and Physical Education, University of Sfax, Sport et Santé, EM2S, LR19JS01, Motricité, Tunisia.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Resting-state degree centrality and Granger causality analysis in relation to facial working memory in patients with first-episode schizophrenia.
Resting-state degree centrality and Granger causality analysis in relation to facial working memory in patients with first-episode schizophrenia.
Fuente:Bmc Psychiatry
Extracto:
Our findings suggest that FSZ patients may have impaired
facial working memory ability, which may be associated with altered functions in
multiple brain regions. Some of these functions are associated with clinical
symptoms, which may provide insight into the underlying neural mechanisms of
schizophrenia.
Claves:Degree centrality, Facial working memory, Granger causality analysis, Resting-state functional magnetic resonance imaging, Schizophrenia
Cita:BMC Psychiatry 2025 Feb 19; 25 (1) : 147.
Autor/es:Zhou, Sumiao (a) Kuang, Qijie (b)
institución:(a) Department of Psychiatry, The Affiliated Brain Hospital, Guangzhou Medical University, 36 Mingxin Road, Liwan District, Guangzhou, 510370, China. (b) Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, 510000, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
(18)F-FDG PET/CT-based intratumoral and peritumoral radiomics combining ensemble learning for prognosis prediction in hepatocellular carcinoma: a multi-center study.
(18)F-FDG PET/CT-based intratumoral and peritumoral radiomics combining ensemble learning for prognosis prediction in hepatocellular carcinoma: a multi-center study.
Fuente:Bmc Cancer
Extracto:
The integrated intratumoral
and peritumoral radiomic model, especially for a 2 mm peritumoral region, was
verified as the optimal radiomic model to predict the overall survival of HCC.
Furthermore, combination of integrated radiomic model with significant clinical
parameter contributed to further enhance the prediction efficacy. TRIAL
REGISTRATION: This study was a retrospective study, so it was free from
registration.
institución:(a) Department of Molecular Imaging and Nuclear Medicine, Tianjin Medical University Cancer Institute and Hospital, Tianjin, 300060, China. (b) Key Laboratory of Cancer Prevention and Therapy, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, 300060, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Harmonising artistic designs with private and collective notions of home: a focus group study of older persons' experiences of art in residential care specialised in dementia care.
Harmonising artistic designs with private and collective notions of home: a focus group study of older persons' experiences of art in residential care specialised in dementia care.
Fuente:Bmc Geriatrics
Extracto:
Clearly defined private
and collective spaces seem to be crucial for fostering self-determination and a
sense of belonging for older persons living in residential care facilities
specialised in dementia care. A balance between private and collective spaces
boosted social engagement, with art playing a key role in reflecting older
persons' previous lives, shared interests and experiences, with co-creation of
artistic design ensuring a dynamic environment.
Claves:Art, Co-creation, Expressions of home, Older people, Residential care facilities
institución:(a) Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. synneve.dahlin-ivanoff@gu.se. (b) Centre for Ageing and Health- AgeCap, University of Gothenburg, Gothenburg, Sweden. synneve.dahlin-ivanoff@gu.se.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Interdisciplinary strategies for establishing a trusting relation as a pre-requisite for existential conversations in palliative care: a grounded theory study.
Interdisciplinary strategies for establishing a trusting relation as a pre-requisite for existential conversations in palliative care: a grounded theory study.
Fuente:Bmc Palliative Care
Extracto:
The interdisciplinary
strategies used to establish existential conversations, the potential barriers to
these conversations and the model we present can be used as a basis for
reflection in professional collaborative learning in PC, as a tool for teachers
in educational PC programmes and as a guide for HCPs in PC.
Autor/es:Lagerin, Annica (a) Melin-Johansson, Christina (b)
institución:(a) Department of Health Care Sciences, Marie Cederschiöld University, Stockholm, Sweden. (b) Department of Health Care Sciences, Marie Cederschiöld University, Stockholm, Sweden. christina.melin-johansson@miun.se.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Predictors of subjective memory functioning in young adults.
Predictors of subjective memory functioning in young adults.
Fuente:Bmc Psychiatry
Extracto:
In conclusion, we revealed that negative
affective states are more pronounced in the satisfaction with memory and
subjective memory complaints in young adults than the objective cognitive
ability.
institución:(a) Department Of Cognitive and Neuropsychology, Institute of Psychology, University of Szeged, Egyetem utca 2, Szeged, H- 6722, Hungary. csabi.eszter@szte.hu. (b) Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, Hungary.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Department of Neurology, Shanxi Bethune Hospital, Third Hospital of Shanxi Medical University, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, China. (b) School of Life Science, Shanxi Normal University, Taiyuan, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Faculté de Médecine Lyon Est, Université Claude Bernard Lyon 1, Lyon, France. (b) Faculté de Médecine Lyon Sud, Université Claude Bernard Lyon 1, Lyon, France.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Stroke etiology and white matter burden in women with and without migraine.
Stroke etiology and white matter burden in women with and without migraine.
Fuente:The Journal of Headache and Pain
Extracto:
Women with both stroke and migraine more often had
undetermined etiology of stroke compared to women with stroke alone, and in women
with stroke alone smoking was a more prevalent risk factor. Migraine did not
contribute to increased WMH volume in women with stroke.
Claves:Cerebrovascular, Headache, MRI, Migraine, Smoking, Stroke, White matter hyperintensities (WMH)
Cita:J Headache Pain 2025 Feb 19; 26 (1) : 37.
Autor/es:Wilms, Anne E (a) van der Weerd, Nelleke (b)
institución:(a) Department of Neurology, Leiden University Medical Center, PO Box 9600, Leiden, 2300RC, The Netherlands. (b) Department of Neurology, Leiden University Medical Center, PO Box 9600, Leiden, 2300RC, The Netherlands.
Conflicto:Declarations. Ethics approval and consent to participate: The Medical Ethics Committee Leiden - Den Haag - Delft (METC-LDD) approved the CREW-MIST (P15.384) and WHISPER (P18.130) study protocols and all participants provided written informed consent prior to study participation. Competing interests: NW, KL and HO report no disclosures. MW was supported by personal grants from the Netherlands Organization for Scientific Research...
(VIDI Grant no. 91717337 and Aspasia grant). TH received support from the Dutch Heart Foundation and the Netherlands Organisation for Scientific Research (NWO), as part of their joint strategic research programme: “Earlier recognition of cardiovascular diseases”. AW and GT and IB report grant support by the European Community (101070917), Stichting Dioraphte (20010407), and the Clayco foundation. In addition, IB reports independent research support from the Dutch Heart Foundation (2020T065), and GT reports additional grants or consultancy support from Abbvie, Novartis, Lilly, Lundbeck, Organon, Pfizer, Teva, and independent support from the Dutch Research Council, Heart Foundation, Dutch Brain Foundation. AMB received honoraria and research/travel grants from Allergan/AbbVie, Amgen/Novartis, Eli Lilly, Pfizer, Satsuma, Teva, and Tonix, and independent support from the Dutch Research Council and ZonMw.
Assessing the efficacy of a virtual reality lower leg fasciotomy surgery training model compared to cadaveric training.
Assessing the efficacy of a virtual reality lower leg fasciotomy surgery training model compared to cadaveric training.
Fuente:Bmc Medical Education
Extracto:
Overall, VR-SET participants were
indistinguishable from the in-person CBT cohort in number of compartments
successfully decompressed. This pilot study suggests utilization of VR
technologies in trauma educational settings may be effective and considered as a
cost-effective solution for training to supplement cadaveric based courses.
Claves:Emergency treatment, Fasciotomy, Lower extremity, Medical education, Trauma, Virtual reality
Cita:BMC Med Educ 2025 Feb 19; 25 (1) : 269.
Autor/es:Groves, Heather (a) Fuller, Kristina (b)
institución:(a) Department of Neurobiology, University of Maryland School of Medicine, 20 Penn St., Rm. 216 (mailing) 685 West Baltimore St., Rm. 280M (office), Baltimore, MD, 21201, USA. (b) Department of Neurobiology, University of Maryland School of Medicine, 20 Penn St., Rm. 216 (mailing) 685 West Baltimore St., Rm. 280M (office), Baltimore, MD, 21201, USA.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Neuropsychiatric and laboratory outcomes of hepatitis C treatment in an early-treated HIV cohort in Thailand.
Neuropsychiatric and laboratory outcomes of hepatitis C treatment in an early-treated HIV cohort in Thailand.
Fuente:Aids Research and Therapy
Extracto:
HCV coinfection
is common in this group of high-risk PWH, highlighting the need for regular
screening, early diagnosis, and treatment. The study participants exhibited a
modest improvement in the CD4 + /CD8 + T-cell ratio and cognitive performance
following DAA therapy and SVR. Future studies should examine potential
neuropsychiatric impacts during early HCV infection as well as the longer-term
neuropsychiatric outcomes after DAA treatment with SVR.
institución:(a) SEARCH Research Foundation, Block 28, 926 Tower C Room C114-C115 Soi Chula 7, Wang Mai, Pathum Wan, Bangkok, 10330, Thailand. ferron.ocampo@gmail.com. (b) SEARCH Research Foundation, Block 28, 926 Tower C Room C114-C115 Soi Chula 7, Wang Mai, Pathum Wan, Bangkok, 10330, Thailand.
Conflicto:Declarations. Ethics approval and consent to participate: The study protocol was approved by the institutional review boards of all relevant collaborating institutions. All participants provided written informed consent. Consent for publication: Not applicable. Competing interests: The RV254/SEARCH 010 study participants received antiretroviral drugs from the Thai Government Pharmaceutical Organization, Gilead Science, Merck, and ViiV Healthcare. SS reports grants from the...
NIH–NIMH and NINDS during the study and nonfinancial support from ViiV Healthcare, Inc., in the form of medications for a clinical trial; study medications were provided to the AIDS Clinical Trials Group for the clinical trial, outside the submitted work. RP and LT reports grants from the NIH–NIMH and NIAID. The other authors report no potential conflicts of interest.
Distinctive autophagy/mitophagy biomarker profiles in frontotemporal lobar degeneration and Alzheimer's disease.
Distinctive autophagy/mitophagy biomarker profiles in frontotemporal lobar degeneration and Alzheimer's disease.
Fuente:Acta Neuropathologica Communications
Extracto:
This is the first
study to explore mitophagy biomarkers in human CSF and serum in FTLD, opening
avenues for further research and potential clinical applications.
institución:(a) Memory Clinic, Department of Neurology, 2nd Faculty of Medicine, Charles University and Motol University Hospital, V Úvalu 84, Prague 5, 150 06, Czech Republic. (b) Memory Clinic, Department of Neurology, 2nd Faculty of Medicine, Charles University and Motol University Hospital, V Úvalu 84, Prague 5, 150 06, Czech Republic.
Conflicto:Declarations. Ethics approval and consent to participate: All study participants signed an informed consent form approved by the Motol University Hospital ethics committee (number EK218/20). Consent for publication: All authors have approved the manuscript and agree with its submission. Competing interests: E.F.F. has an MTA with LMITO Therapeutics Inc (South Korea), a CRADA arrangement with ChromaDex (USA), and a commercialization...
agreement with Molecule AG/VITADAO, and is a consultant to Aladdin Healthcare Technologies (UK and Germany), the Vancouver Dementia Prevention Centre (Canada), Intellectual Labs (Norway), MindRank AI (China), and NYO3 (China). J.H. is a medical advisor at Neurona lab, Terrapino mobile app, consulted for Eisai, Eli Lilly, Biogen, Schwabe, holds stock options in Alzheon. K.V., J.L., A.K., H.H., V.M., F.A., M.L., Z.N., H.-L.W., J.Z., L.S., and M.V. have nothing to disclose.
Own-gender bias in facial feature recognition yields sex differences in holistic face processing.
Own-gender bias in facial feature recognition yields sex differences in holistic face processing.
Fuente:Biology of Sex Differences
Extracto:
Our results suggest a possible modulation of face encoding and/or
recognition by sex and hormone status. Moreover, the established own-gender bias
in face recognition, that is, female advantage in recognition of faces of the
same gender might be based on more accurate representations of face-parts.
Cita:Biol Sex Differ 2025 Feb 19; 16 (1) : 14.
Autor/es:Hausinger, Tobias (a) Probst, Björn (b)
institución:(a) Centre for Cognitive Neuroscience, University of Salzburg, 5020, Salzburg, Austria. tobias.hausinger@plus.ac.at. (b) Department of Psychology, University of Salzburg, 5020, Salzburg, Austria. tobias.hausinger@plus.ac.at.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Density and entropy of immune cells within the tumor microenvironment of primary tumors and matched brain metastases.
Density and entropy of immune cells within the tumor microenvironment of primary tumors and matched brain metastases.
Fuente:Acta Neuropathologica Communications
Extracto:
These findings highlight the potential of targeting TAMs as a
therapeutic strategy to mitigate the development of brain metastases.
Cita:Acta Neuropathol Commun 2025 Feb 19; 13 (1) : 34.
Autor/es:Kleinberger, Markus (a) Çifçi, Didem (b)
institución:(a) Division of Oncology, Department of Medicine I, Medical University of Vienna, Waehringer Guertel 18-20, Vienna, 1090, Austria. (b) Christian Doppler Laboratory for Personalized Immunotherapy, Department of Medicine I, Medical University of Vienna, Vienna, Austria.
Conflicto:Declarations. Ethics approval and consent to participate: This study was approved by the Ethics Committees of the Medical University of Vienna (approval no. 1692/2022, 1895/2022). Consent for publication: Not applicable. Competing interests: M.J.M. received research funding from Bristol-Myers Squibb and travel support from Pierre Fabre. A.S.B. received research support from Daiichi Sankyo, Roche, and honoraria for lectures, consultation or advisory...
board participation from Roche, Bristol-Meyers Squibb, Merck, Daiichi Sankyo as well as travel support from Roche, Amgen and AbbVie. Z.S. is a former employee of Boehringer Ingelheim and Turbine AI. M.P. received honoraria for lectures, consultation, or advisory board participation from the following for-profit companies: Bayer, Bristol-Myers Squibb, Novartis, Gerson Lehrman Group (GLG), CMC Contrast, GlaxoSmithKline, Mundipharma, Roche, BMJ Journals, MedMedia, Astra Zeneca, AbbVie, Lilly, Medahead, Daiichi Sankyo, Sanofi, Merck Sharp & Dome, Tocagen. J.N.K declares consulting services for Bioptimus, France; Owkin, France; DoMore Diagnostics, Norway; Panakeia, UK; AstraZeneca, UK; Scailyte, Switzerland; Mindpeak, Germany; and MultiplexDx, Slovakia. Furthermore he holds shares in StratifAI GmbH, Germany, has received a research grant by GSK, and has received honoraria by AstraZeneca, Bayer, Daiichi Sankyo, Eisai, Janssen, MSD, BMS, Roche, Pfizer and Fresenius.
Extracto:
LLMs have potential as
complementary tools in migraine literature analysis. Despite some inconsistencies
in output and methodological limitations, the results highlight the utility of
LLMs in enhancing the efficiency of literature review through sentiment analysis.
Claves:Artificial intelligence, Headaches, Large language model, Literature review, Migraine
Cita:BMC Neurol 2025 Feb 19; 25 (1) : 69.
Autor/es:Mackenzie, Elyse (a) Cheng, Roger (b)
institución:(a) Department of Neurology, Rutgers Robert Wood Johnson Medical School, New Jersey, USA. (b) Department of Neurology, Rutgers Robert Wood Johnson Medical School, New Jersey, USA.
Conflicto:Declarations. Ethics approval and consent to participate: N/A. Consent for publication: N/A. Competing interests: PZ: He has received honorarium from Alder Biopharmaceuticals, Board Vitals, and Fieve Clinical Research. He collaborates with Headache Science Incorporated without receiving financial support. He had ownership interest in Cymbeline LLC. He is a consultant for Acument LLC.
Thyroidectomy under local versus general anesthesia in health camp settings in Uganda: a randomized prospective equivalence single-blind controlled trial.
Thyroidectomy under local versus general anesthesia in health camp settings in Uganda: a randomized prospective equivalence single-blind controlled trial.
Fuente:Bmc Surgery
Tipo de trabajo:Estudio clínico
Extracto:
Thyroidectomy under LA can be performed in a
well-selected patient population with low complication rates and comparable
patient satisfaction to GA. These findings may support LA for thyroidectomy as a
valuable cost-efficient alternative, especially in low-resource settings with
fewer GA providers. TRIAL REGISTRATION: First registered on 31/07/2022,
PACTR202208635457430 by Pan African Clinical Trial Registry.
Claves:Africa, Critical care, General anesthesia, Local anesthesia, Thyroidectomy
Cita:BMC Surg 2025 Feb 19; 25 (1) : 73.
Autor/es:Kabuye, Umaru (a) Fualal, Jane Odubu (b)
institución:(a) Department of Surgery, Kampala International University Western Campus, Bushenyi, Uganda. kabuyeomar@gmail.com. (b) Department of Surgery, Kampala International University Western Campus, Bushenyi, Uganda.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Associations between internal exposure to acrylamide and sleep health: evidence from NHANES 2013-2016.
Associations between internal exposure to acrylamide and sleep health: evidence from NHANES 2013-2016.
Fuente:Bmc Public Health
Extracto:
The findings shed light on the potential
effects of AA's health threat and future research is warranted to develop
intervention strategies.
Claves:Acrylamide, Glycidamide, N-Acetyl-S-(2-carbamoylethyl)-L-cysteine, Short sleep duration, Systemic inflammation
Cita:BMC Public Health 2025 Feb 19; 25 (1) : 679.
Autor/es:Gan, Lin (a) Wang, Jiaoyang (b)
institución:(a) Department of Neurology and Neuroscience Center, The First Hospital of Jilin University, Xinmin Street #1, Changchun, China. (b) Department of Neurology and Neuroscience Center, The First Hospital of Jilin University, Xinmin Street #1, Changchun, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Leukemia and risk of stroke: a Mendelian randomization analysis.
Leukemia and risk of stroke: a Mendelian randomization analysis.
Fuente:Bmc Neurology
Extracto:
Our Mendelian randomization analysis revealed that chronic
lymphocytic leukemia (CLL) was associated with an increased risk of ischemic
stroke (IS) but not intracerebral hemorrhage (ICH). Conversely, there was no
evidence supporting causal associations of chronic myeloid leukemia (CML), acute
lymphoblastic leukemia (ALL), or acute myeloid leukemia (AML) with either type of
stroke. These findings enhance our comprehension of the intricate interplay
between various leukemia subtypes and the risk of stroke. Further research is
essential to delve into the underlying mechanisms and potential clinical
implications of these observed associations.
institución:(a) Department of Neurosurgery, The Second Affiliated Hospital of Chongqing Medical University, 74 Linjiang Rd, Yuzhong, Chongqing, 400010, China. (b) Nursing (Cooperation with JAMK University of Applied Sciences), School of Nursing, Beihua University, No. 3999 Binjiang East Road, Jilin City, Jilin Province, 132000, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Weight bias among students and employees in university settings: an exploratory study.
Weight bias among students and employees in university settings: an exploratory study.
Fuente:Bmc Public Health
Extracto:
Various factors are associated with the experience of weight bias and
stigmatization towards people with higher weight in the college population.
Campaigns to prevent and reduce weight-related bias should be aimed specifically
at staff members as well as students. Future research should examine weight bias
internalization as a mediator between self-perceived weight and prejudice.
Autor/es:Sohier, Léonie (a) Brearty, Claudia Mc (b)
institución:(a) School of Psychology, Université Laval, Québec, QC, Canada. (b) Research Center of the Quebec Heart and Lung Institute, 2725 Ch Ste-Foy, Québec, QC, G1V4G5, Canada.
Conflicto:Declarations. Ethics approval and consent to participate: This study was approved by the ethics committee of Université Laval (Comité d’éthique de la recherche avec des êtres humains de l’Université Laval; 2022-075/31-03-2022). All participants gave their informed consent to participate. Consent for publication: not applicable. Competing interests: SI Conferences: invitations as a speaker for Novo Nordisk, Takeda Canada, Bausch Health Canada;...
h Canada; clinical trials as the main investigator for Takeda Canada. LS, CMB, SL, DJC, AS-L, SS, LP, IAM, M-PG-G and CL: No competing interest.
