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The increasing number of Open Access articles widens the reading offer
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SIIC created, produced and handles the AFT software that deciphers
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While most of the selected texts belong to original articles,
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Carbapenem-resistant Klebsiella pneumoniae infections after liver transplantation: Drug resistance, risk factors and impact on prognosis.
Carbapenem-resistant Klebsiella pneumoniae infections after liver transplantation: Drug resistance, risk factors and impact on prognosis.
Fuente:World Journal of Gastroenterology
Extracto:
CRKP infections were
frequent complications following LT, with poor associated outcomes. Risk factors
for post-LT CRKP infections included female sex, significant intraoperative
bleeding, elevated alanine aminotransferase levels, and the need for mechanical
ventilation. CRKP infections negatively impacted survival and led to prolonged
ICU stays.
Cita:World J Gastroenterol 2025 Feb 28; 31 (8) : 98415.
Autor/es:Liu, Tao-Hua (a) Chen, Li-Hua (b)
institución:(a) Department of Pediatrics, The Third Xiangya Hospital of Central South University, Changsha 410013, Hunan Province, China. (b) Department of Laboratory Medicine, The Third Xiangya Hospital of Central South University, Changsha 410013, Hunan Province, China.
Conflicto:Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Machine learning model-based prediction of postpancreatectomy acute pancreatitis following pancreaticoduodenectomy
Machine learning model-based prediction of postpancreatectomy acute pancreatitis following pancreaticoduodenectomy
Fuente:World Journal of Gastroenterology
Tipo de trabajo:Estudio de cohortes
Extracto:
We developed the first machine learning-based
predictive model for PPAP following PD. This predictive model can assist surgeons
in anticipating and managing this complication proactively.
Claves:Acute pancreatitis, Machine learning, Pancreaticoduodenectomy, Postoperative complication, Predictive value
Cita:World J Gastroenterol 2025 Feb 28; 31 (8) : 102071.
Autor/es:Ma, Ji-Ming (a) Wang, Peng-Fei (b)
institución:(a) Hepatopancreatobiliary Center, Beijing Tsinghua Changgung Hospital, Beijing 102218, China. (b) Hepatopancreatobiliary Center, Beijing Tsinghua Changgung Hospital, Beijing 102218, China.
Conflicto:Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Irritable bowel syndrome remains a complex disorder of gut-brain interaction: Too many actors on stage.
Irritable bowel syndrome remains a complex disorder of gut-brain interaction: Too many actors on stage.
Fuente:World Journal of Gastroenterology
Extracto:
This invited letter to the editor summarizes the main
results of the aforementioned study and highlights its multiparametric approach,
including variables not strictly gastroenterological, in the study of IBS, and
discusses its strengths and limitations.
institución:(a) Division of Hepatogastroenterology, Department of Precision Medicine, University of Campania Luigi Vanvitelli, Naples 80138, Italy. raffaele.pellegrino@unicampania.it. (b) Division of Hepatogastroenterology, Department of Precision Medicine, University of Campania Luigi Vanvitelli, Naples 80138, Italy.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Lymph node metastatic patterns of gastric carcinoma with a combination of adenocarcinoma and neuroendocrine carcinoma components.
Lymph node metastatic patterns of gastric carcinoma with a combination of adenocarcinoma and neuroendocrine carcinoma components.
Fuente:World Journal of Gastroenterology
Extracto:
We found
a significant correlation between the NEC percentage, tumour invasion depth,
Lauren classification, and tumour location and LN metastasis patterns in G-ANEC.
For G-ANEC, a lower proportion of NEC or AC in the primary lesion does not
preclude the possibility of these components metastasizing to the LNs. Different
adjuvant chemotherapy regimens should be administered on the basis of the varying
components of LN metastasis in patients with G-ANEC.
Cita:World J Gastroenterol 2025 Feb 28; 31 (8) : 102347.
Autor/es:Zhou, Kai (a) Li, Zhong-Wu (b)
institución:(a) Department of Gastrointestinal Surgery, Peking University Cancer Hospital and Institute, Beijing 100142, China. (b) Department of Pathology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital and Institute, Beijing 100142, China.
Conflicto:Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Multiple primary cancers with gastrointestinal malignant tumors as the first manifestation
Multiple primary cancers with gastrointestinal malignant tumors as the first manifestation
Fuente:World Journal of Gastroenterology
Tipo de trabajo:Revisión
Extracto:
Patients with GI malignancies face a higher MPC risk.
Developing screening and follow-up protocols may enhance detection and treatment
outcomes.
Cita:World J Gastroenterol 2025 Feb 28; 31 (8) : 100146.
Autor/es:Bi, Xin-Ran (a) Zhao, Shuang-Yan (b)
institución:(a) The First Clinical Medical College of Gansu University of Traditional Chinese Medicine, Lanzhou 730000, Gansu Province, China. (b) Department of Radiotherapy Center, Gansu Provincial Hospital, Lanzhou 730000, Gansu Province, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Role of Helicobacter pylori infection and the risk of cholelithiasis.
Role of Helicobacter pylori infection and the risk of cholelithiasis.
Fuente:World Journal of Gastroenterology
Extracto:
pylori infection is positively correlated with cholelithiasis,
particularly with the choledocholithiasis phenotype, especially in Asia, and it
is potentially related to bilirubin and cholesterol metabolism.
Cita:World J Gastroenterol 2025 Feb 28; 31 (8) : 102024.
Autor/es:Fabbri, Nicolò (a) Greco, Salvatore (b)
institución:(a) Unit of General Surgery, Local Health Agency of Ferrara, Ferrara 44100, Emilia-Romagna, Italy. n.fabbri@ausl.fe.it. (b) Unit of Internal Medicine, Local Health Agency of Ferrara, Ferrara 44100, Emilia-Romagna, Italy.
Conflicto:Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
New frontiers in hepatocellular carcinoma: Precision imaging for microvascular invasion prediction.
New frontiers in hepatocellular carcinoma: Precision imaging for microvascular invasion prediction.
Fuente:World Journal of Gastroenterology
Extracto:
This editorial commends
the study's contribution to precision medicine and discusses its implications for
future research and clinical practice.
Cita:World J Gastroenterol 2025 Feb 28; 31 (8) : 102224.
Autor/es:Hao, Liang (a) Zhang, Zhao-Nan (b)
institución:(a) Cancer Center, Yantai Affiliated Hospital of Binzhou Medical University, The 2nd Medical College of Binzhou Medical University, Yantai 264100, Shandong Province, China. (b) Cancer Center, Yantai Affiliated Hospital of Binzhou Medical University, The 2nd Medical College of Binzhou Medical University, Yantai 264100, Shandong Province, China.
Conflicto:Conflict-of-interest statement: There is no conflict of interest associated with any of the senior authors or other coauthors who contributed their efforts to this manuscript.
Mind the gut: Navigating the complex landscape of gastroprotection in neurosurgical patients.
Mind the gut: Navigating the complex landscape of gastroprotection in neurosurgical patients.
Fuente:World Journal of Gastroenterology
Extracto:
This
editorial underscores the need for tailored approaches and encourages further
investigation into optimal gastroprotective strategies for neurosurgical
patients.
institución:(a) Department of Neurosurgery, University of Flordia, Gainesville, FL 32608, United States. (b) Department of Neurosurgery, University of Flordia, Gainesville, FL 32608, United States. brandon.lucke-wold@neurosurgery.ufl.edu.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Evidence-based control of stress response on intraoperative physiological indexes and recovery of patients undergoing gastrointestinal surgery.
Evidence-based control of stress response on intraoperative physiological indexes and recovery of patients undergoing gastrointestinal surgery.
Fuente:World Journal of Gastroenterology
Tipo de trabajo:Guía de práctica clínica
Extracto:
The evidence-based nursing measures
targeting stress responses based on the conventional ERAS nursing model resulted
in stable intraoperative physiological parameters during surgery, promoted
postoperative recovery, and reduced the incidence of complications.
Cita:World J Gastroenterol 2025 Feb 28; 31 (8) : 102331.
Autor/es:Yuan, Chen-Dong (a) Zhou, Bao-Zhu (b)
institución:(a) Department of General Surgery, The First Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China. (b) Department of Anesthesiology, The First Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China.
Conflicto:Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Limitations and enhancement opportunities for variceal rebleeding prediction model in patients with cirrhosis.
Limitations and enhancement opportunities for variceal rebleeding prediction model in patients with cirrhosis.
Fuente:World Journal of Gastroenterology
Extracto:
Prospective validation and inclusion of additional variables are
recommended to enhance predictive accuracy across diverse clinical scenarios.
Cita:World J Gastroenterol 2025 Feb 28; 31 (8) : 102841.
Autor/es:Chen, Guang-Bin (a) Wu, Fei (b)
institución:(a) Department of Hepatobiliary Surgery, The Second People's Hospital of Wuhu, Wuhu Hospital Affiliated to East China Normal University, Wuhu 241000, Anhui Province, China. (b) Graduate School, Wannan Medical College, Wuhu 241000, Anhui Province, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Radiation-Enhanced AF1q Moves Center Stage as a Key Driver to Favorable Tumor Stage in Rectal Cancer Patients.
Radiation-Enhanced AF1q Moves Center Stage as a Key Driver to Favorable Tumor Stage in Rectal Cancer Patients.
Fuente:Cancer Medicine
Extracto:
AF1q is expressed in
RC, especially after short-term radiation therapy. Here, AF1q may support tumor
suppression, possibly through the involvement of the pro-apoptotic STAT1 axis.
Further mechanistic evidence and investigation involving a larger patient cohort
are needed to validate a radiation-induced, AF1q-driven tumor-suppressing effect,
which may impact RC patient outcomes.
Cita:Cancer Med 2025 Mar; 14 (5) : e70658.
Autor/es:Gruber, Elisabeth S (a) Oberhuber, Georg (b)
institución:(a) Division of Visceral Surgery, Department of General Surgery, Medical University Vienna, Vienna, Austria. (b) Department of Experimental and Animal Pathology, Clinical Institute of Pathology, Medical University Vienna, Vienna, Austria.
Use and misuse of domperidone in patients living with Parkinson disease in France.
Use and misuse of domperidone in patients living with Parkinson disease in France.
Fuente:Fundamental & Clinical Pharmacology
Tipo de trabajo:Guía
Extracto:
Domperidone is still prescribed in
France for PD patients with dopaminergic-induced nausea, mostly disregarding EMA
guidelines due to patient age (>60 years) and prolonged treatment (>7 days). Our
study underscores the unmet need for managing gastrointestinal symptoms in PD,
highlighting the inadequacy of EMA guidelines in this population.
Autor/es:Januel, Edouard (a) Corvol, Jean Christophe (b)
institución:(a) Département de Santé Publique, Centre de Pharmacoépidémiologie (Cephepi), Unité de Recherche Clinique PSL-CFX, CIC-1901, Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, équipe PEPITES, AP-HP, Hôpital Pitié Salpêtrière, Paris, France. (b) Department of Neurology, CIC Neurosciences, NS-PARK/FCRIN Network, Hôpital Pitié-Salpêtrière, Sorbonne Université, Assistance Publique Hôpitaux de Paris, Paris Brain Institute - ICM, Inserm, CRNS, Paris, France.
Mode of delivery among preterm twins and offspring health, a retrospective cohort study.
Mode of delivery among preterm twins and offspring health, a retrospective cohort study.
Fuente:European Journal of Pediatrics
Extracto:
Cesarean delivery in preterm twins is
associated with long-term respiratory, neurologic, infectious and
gastrointestinal morbidities of the offspring. The findings suggest the potential
benefits of vaginal over cesarean deliveries regarding offspring long-term health
complications. WHAT IS KNOWN: • Studies on singleton births show that cesarean
delivery may increase respiratory, infectious, neurological and gastrointestinal
outcomes remains inconsistent across term and preterm deliveries. • Cesarean
delivery rates remain high despite recommendations to reduce their frequency, yet
data on the association between cesarean delivery and morbidity among twins,
particularly in small for gestational age twins, is limited. WHAT IS NEW: • This
is the first large-scale study demonstrating that cesarean delivery in preterm
twins increases the odds of respiratory, neurologic, infectious and
gastrointestinal long-term morbidities up to age 18. • The higher rates of
respiratory, neurologic, infectious, and gastrointestinal complications persist
even in uncomplicated cesarean deliveries.
Claves:Long-term morbidity, Mode of delivery, Preterm twins
Cita:Eur J Pediatr 2025 Mar 10; 184 (3) : 234.
Autor/es:Shitrit, Itamar Ben (a) Sheiner, Eyal (b)
institución:(a) Department of Epidemiology, Biostatistics and Community Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel. itamab@post.bgu.ac.il. (b) Clinical Research Center, Soroka University Medical Center, PO Box 151, 84101, Be'er-Sheva, Israel. itamab@post.bgu.ac.il.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Respiratory Viral Co-infection in SARS-CoV-2-Infected Children During the Early and Late Pandemic Periods.
Respiratory Viral Co-infection in SARS-CoV-2-Infected Children During the Early and Late Pandemic Periods.
Fuente:The Pediatric Infectious Disease Journal
Extracto:
Approximately 1 in 5 children infected with SARS-CoV-2 had co-infection with
another respiratory virus, and co-infection with rhinovirus/enterovirus was
associated with severe outcomes. When public health restrictions were relaxed,
co-infections increased.
institución:(a) From the Department of Pediatrics, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada. (b) Department of Pediatrics, Feinberg School of Medicine, Northwestern University and Division of Emergency Medicine, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.
Relating the molecular phenotype of ulcerative colitis to the clinical course.
Relating the molecular phenotype of ulcerative colitis to the clinical course.
Fuente:Scientific Reports
Extracto:
The molecular features of UC
showed strong correlations with disease activity and permitted development of
machine-learning predictive disease classifiers that can be applied to expanded
testing in diverse cohorts.
Autor/es:Madill-Thomsen, Katelynn S (a) Venner, Jeffery M (b)
institución:(a) Department of Medicine, University of Alberta, Edmonton, AB, Canada. (b) Alberta Transplant Applied Genomics Center, University of Alberta, Edmonton, AB, Canada.
Conflicto:Declarations. Competing interests: P.F. Halloran holds shares in Transcriptome Sciences Inc (TSI), a University of Alberta research company dedicated to developing molecular diagnostics, supported in part by a licensing agreement between TSI and Thermo Fisher, and by a research grant from Natera. P.F. Halloran is a consultant to Natera. Thermo Fisher and Natera had no role in the study design,...
analysis, or reporting of results. The other authors have nothing to declare.
Exploring the influence of polysaccharide on gastrointestinal stability, drug release and formation mechanism of nanoparticles in Zhimu and Huangbai herb pair decoction.
Exploring the influence of polysaccharide on gastrointestinal stability, drug release and formation mechanism of nanoparticles in Zhimu and Huangbai herb pair decoction.
Fuente:Scientific Reports
Extracto:
In conclusion, polysaccharides of ZBD were essential for
N-ZBD formation, and could protect the stability of N-ZBD in the gastrointestinal
environment and contribute to its slow drug release.
Claves:Drug release, Gastrointestinal stability, Nanoparticles, Polysaccharide, Zhimu and Huangbai herb pair decoction
Cita:Sci Rep 2025 Mar 10; 15 (1) : 8293.
Autor/es:Nie, Wenlong (a) Zhang, Xinyu (b)
institución:(a) School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China. (b) School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
institución:(a) Department of Bacteriology and Virology, School of Medicine, Shiraz University of Medical Science, Shiraz, Iran. (b) Research Center for Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Transcriptome combined with single-cell sequencing explored prognostic markers associated with T cell exhaustion characteristics in head and neck squamous carcinoma.
Transcriptome combined with single-cell sequencing explored prognostic markers associated with T cell exhaustion characteristics in head and neck squamous carcinoma.
Fuente:Scientific Reports
Extracto:
The insights
from this study provide a valuable foundation for future investigations into the
molecular mechanisms and immune landscape associated with the progression from
normal tissue to malignant squamous cell carcinoma.
Claves:Head and neck squamous cell carcinoma, Prognosis, Single-cell sequencing, T cell exhaustion, Transcriptome
Cita:Sci Rep 2025 Mar 10; 15 (1) : 8209.
Autor/es:Liu, Jie (a) Li, Penghui (b)
institución:(a) Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, China. (b) Department of Gastrointestinal surgery, The First Affiliated Hospital, College of Clinical Medicine, Henan University of Science and Technology, Luoyang, 471000, Henan, China.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación
Combination of gut microbiota, proinflammatory cytokine, and (18)F-FDG PET as potential indicators for predicting breast cancer recurrence.
Combination of gut microbiota, proinflammatory cytokine, and (18)F-FDG PET as potential indicators for predicting breast cancer recurrence.
Fuente:Scientific Reports
Extracto:
An integrated predictive model combining gut microbiota
composition, cytokine levels, PET indices, and clinical factors demonstrated
superior accuracy (AUC: 0.9025) in predicting breast cancer recurrence compared
to individual components.
Claves:18F-FDG PET, Breast cancer, Gut microbiota, Pro-inflammatory cytokine, Recurrence, Spleen uptake, Tumor uptake
Cita:Sci Rep 2025 Mar 10; 15 (1) : 8313.
Autor/es:An, Jeongshin (a) Kim, Bom Sahn (b)
institución:(a) Institute of Convergence Medicine Research, Ewha Womans University Mokdong Hospital, Ewha Womans University College of Medicine, 1071 Anyangcheon‑ro, Yangcheon‑gu, Seoul, 07985, Republic of Korea. (b) Department of Surgery, Ewha Womans University Mokdong Hospital, Ewha Womans University School of Medicine, 1071 Anyangcheon‑ro, Yangcheon‑gu, Seoul, 07985, Republic of Korea.
Conflicto:Los autores declaran no tener conflictos de interés con la investigación