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EXPOSIÇAO AOS POLUENTES DA QUEIMA DE CANAVIAIS E O RISCO PARA SAUDE

(especial para SIIC © Derechos reservados)
Esta revisão aborda a interação entre o ambiente e a herança genética no aparecimento do câncer, assim como apresenta as ferramentas disponíveis para a detecção do risco de exposição a esses compostos, facilitando a aplicação de estratégias de prevenção da doença.
bosso9.jpg Autor:
Rosa maria Bosso,
Columnista Experto de SIIC

Institución:
Instituto de Biociências, Letras e Ciências Exatas Universidade Estadual Paulista (UNESP)

Artículos publicados por Rosa maria Bosso,
Coautor
Nívea Conforti-Froes.* 
Doutor em Genética, Pós-Doutor em Medicina Preventiva. Universidade Estadual Paulista (UNESP). Instituto de Biociencias, Letras e Ciencias Exatas, campus de Sao José do Rio Preto.*
Recepción del artículo
21 de Abril, 2004 		Aprobación
3 de Agosto, 2004
Primera edición
6 de Diciembre, 2004 		Segunda edición, ampliada y corregida
7 de Junio, 2021

EXPOSIÇAO AOS POLUENTES DA QUEIMA DE CANAVIAIS E O RISCO PARA SAUDE

Resumen
No Brasil, na época da colheita da cana-de-açúcar, costuma-se queimar previamente a plantação para facilitar o corte. No período da safra, os cortadores de cana estão expostos a vários produtos originados da combustão de matéria orgânica, incluindo os hidrocarbonetos aromáticos policíclicos (polycyclic aromatic hydrocarbons [PAHs]), compostos já conhecidos por sua ação mutagênica e/ou carcinogênica. O cortadores de cana também apresentam um aumento de problemas respiratórios, possivelmente resultante da exposição aos poluentes originados da queima de canaviais. Muitas das enzimas envolvidas no processos de ativação e destoxificação dos PAHs são polimórficas. Os polimorfismos genéticos podem desempenhar um papel importante no aumento da suscetibilidade a tumores induzidos por xenobióticos. Esta revisão aborda a interação entre o ambiente e a herança genética no aparecimento do câncer, assim como apresenta as ferramentas disponíveis para a detecção do risco de exposição a esses compostos, facilitando a aplicação de estratégias de prevenção da doença.

Palabras clave
Hidrocarbonetos aromáticos policíclicos, cana-de-açúcar queimada, polimorfismos genéticos, poluentes ambientais, estratégias de prevenção do câncer


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EXPOSURE TO POLLUTANTS OF SUGAR CANE PLANTATION BURNT AND HEALTH RISK

Abstract
In Brazil, the leaves of the sugar cane are burnt before harvesting in order to make the process of cutting easier. During the harvest time, the sugar cane workers are exposed to various combustion products of organic materials including polycyclic aromatic hydrocarbons (PAHs) which are known to be mutagenic and/or carcinogenic. The workers also have an increased risk of lung respiratory disorders, possibly due to pollutants exposure derived from the practice of burning foliage during the cane-cutting time. Many of the enzymes involved in the activation and detoxification processes of PAHs are genetically polymorphic. Genetic polymorphims can play an important role in increasing susceptibility to xenobiotic-induced tumors. This review approaches the interaction between environmental pollutants and genetic inheritance in the carcinogenic process, as well as the current available tools for risk detection of environmental exposure, thus enabling the application of cancer-prevention public strategies.

Key words
Polycyclic aromatic hydrocarbons (PAHs), sugar cane burnt, genetic polymorphism, environmental pollutants, cancer prevention strategies

Clasificación en siicsalud
Artículos originales > Expertos de Iberoamérica >
página   www.siicsalud.com/des/expertocompleto.php/

Especialidades
Principal: Medicina del Trabajo, Oncología
Relacionadas: Bioquímica, Epidemiología, Genética Humana, Salud Pública



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Bosso, Rosa Maria
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