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LINFOCITOS T COOPERADORES EN PACIENTES CON RINITIS ALERGICA Y ASMA EXTRINSECA TRATADOS CON INMUNOTERAPIA

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La inmunoterapia produce cambios complejos en la inmunorregulación, caracterizados por la disminución de los niveles de interleucina 10.
Autor:
Daniel Aguilar angeles
Columnista Experto de SIIC
Artículos publicados por Daniel Aguilar angeles
Coautores
Ernestina Serrano Miranda* Isabel Rojo Gutiérrez** Sergio Estrada Parra*** Mario Alberto Bermejo Guevara**** 
Doctora en Ciencias. Escuela Nacional de Ciencias Biológicas del Instituto Politécnico Nacional*
Especialista en Alergia e Inmunología Clínica. Hospital Juárez**
Doctor en Ciencias. Escuela Nacional de Ciencias Biológicas del Instituto Politécnico Nacional***
Hospital Juárez****
Recepción del artículo
6 de Abril, 2005 		Primera edición
25 de Octubre, 2005 		Segunda edición, ampliada y corregida
7 de Junio, 2021

LINFOCITOS T COOPERADORES EN PACIENTES CON RINITIS ALERGICA Y ASMA EXTRINSECA TRATADOS CON INMUNOTERAPIA

Resumen
Las enfermedades alérgicas representan un grupo de patologías inmunológicas con alteraciones en el equilibrio a nivel de linfocitos T en sus subpoblaciones Th1/Th2. La inmunoterapia demostró tener actividad correctora en esta patología, por lo que se la considera un tratamiento etiológico. Se estudiaron 10 pacientes, 6 con rinitis alérgica y 4 con asma alérgica sensibles a ácaros para someterlos a inmunoterapia específica durante 52 semanas, empleando la funcionalidad in vitro de la inmunidad celular. En los resultados obtenidos se encontraron cambios en la inmunorregulación, caracterizados por la disminución de la IL-10. Además encontramos que los linfocitos TCD8+ también elaboran IL-10.

Palabras clave
Inmunoterapia, asma, rinitis


Artículo completo
(castellano)
Extensión:  +/-4.38 páginas impresas en papel A4
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HELPER T LYMPHOCYTES IN PATIENTS WITH ALLERGIC RINITHIS AND EXTRINSEC ASTHMA TREATED WITH IMMUNOTHERAPY

Abstract
Allergic illnesses represent a group of immunologic pathologies with balance alterations at T lymphocyte level in Th1/Th2 sub-populations. Immunotherapy has shown to have a corrective activity towards this pathology, for which it is considered an etiological treatment. 10 patients were studied, 6 with allergic rhinitis and 4 others with allergic asthma, sensitive to acaroids. They were subject to immunotherapy for a period of 52 weeks, using the in vitro function of cellular immunity. Changes in immunoregulation, characterized by a reduction of IL-10, were observed in the results obtained. TCD8+ lymphocytes also produce IL-10.

Key words
Inmunoterapia, asma, rinitis

Clasificación en siicsalud
Artículos originales > Expertos de Iberoamérica >
página   www.siicsalud.com/des/expertocompleto.php/

Especialidades
Principal: Alergia
Relacionadas: Bioquímica, Farmacología, Inmunología, Medicina Farmacéutica, Medicina Interna



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Bibliografía del artículo
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Título español
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 Autoevaluación
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