Carla C. C. R. de Carvalho *

Autora invitada por SIIC

O artigo revê as diferentes aplicações da carvona e discute processos de produção

CARVONA: PORQUÊ E COMO PRODUZIR ESTE TERPENO

As várias aplicações da carvona, como fragrância e sabor, inibidor da germinação em batatas, agente anti-microbiano, precursor de compostos químicos, indicador bioquímico do ambiente, bem como as suas aplicações no campo médico, justificam a investigação desenvolvida para aumentar a produção mundial deste terpeno.

*Carla C. C. R. de Carvalho
describe para SIIC los aspectos relevantes de su trabajo
CARVONE: WHY AND HOW SHOULD ONE BOTHER TO PRODUCE THIS TERPENE
Institución principal de la investigación
*Centro de Ingeniería Biológica y Química, Instituto Superior Técnico, Lisboa, Portugal
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Referencias bibliográficas
1. Plinius Secundus G, (77 A.D.). Naturalis Historiae (Natural History (1952) Pliny the Elder, Trans.). Cambridge, USA: Harvard University Press, The Loeb Classical Library.
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4. McGeady P, Wansley DL, Logan DA. Carvone and perillaldehyde interfere with the serum-induced formation of filamentous structures in Candida albicans at substantially lower concentrations than those causing significant inhibition of growth. Journal of Natural Products 2002; 65:953-955.
5. Raphael TJ, Kuttan G. Immunomodulatory activity of naturally occurring monoterpenes carvone, limonene, and perillic acid. Immunopharmacology and Immunotoxicology 2003; 25:285-294.
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7. Franzios G, Mirotsou M, Hatziapostolou E, Kral J, Scouras ZG, Mavragani-Tsipidou P. Insecticidal and genotoxic activities of mint essential oils. Journal of Agricultural and Food Chemistry 45, 2690-2694.
8. Vartak PH, Sharma RN. Vapor toxicity and repellence of some essential oils and terpenoids to adults of Aedes aegypti (L) (Diptera, Culicidae). Indian Journal of Medical Research Section A-Infectious Diseases 1993; 97:122-127.
9. Berta F, Supuka J, Chladna A. The composition of terpenes in needles of Pinus sylvestris in a relatively clear and in a city environment. Biologia 52:71-78.
10. Supuka J, Berta F. The composition of terpenes in needles of white pine (Pinus strobus L.) growing in urban environment. Ekologia-Bratislava 17:419-433.
11. Vanek T, Valterova I, Vankova R, Vaisar T. Biotransformation of (-)-limonene using Solanum aviculare and Dioscorea deltoidea immobilized plant cells. Biotechnology Letters 1999; 21:625-628.
12. Onken J, Berger RG. Effects of R-(1)-limonene on submerged cultures of the terpene transforming basidiomycete Pleurotus sapidus. Journal of Biotechnology 1999; 69:163–168.
13 Noma Y, Asakawa Y. Enantio- and diastereoselectivity in the biotransformation of carveols by Euglena gracilis Z. Phytochemistry 1992; 31:2009-2011.
14. Duetz WA, Fjallman AHM, Ren SY, Jourdat C, Witholt B. Biotransformation of D-limonene to (+) trans-carveol by toluene-grown Rhodococcus opacus PWD4 cells. Applied and Environmental Microbiology 2004; 67:2829-2832.
15. De Carvalho CCCR, Da Fonseca MMR. Towards the bio-production of trans-carveol and carvone from limonene: induction after cell growth on limonene and toluene. Tetrahedron: Asymmetry 2003; 14:3925-3931.
16. De Carvalho CCCR, Da Fonseca MMR. Influence of reactor configuration on the production of carvone from carveol by whole cells of Rhodococcus erythropolis DCL14. Journal of Molecular Catalysis B-Enzymatic 19:377-387.
17. De Carvalho CCCR, Poretti A, Da Fonseca MMR. Cell adaptation to substrate, solvent and product: a successful strategy to overcome product inhibition in a bioconversion system, Applied Microbiology and Biotechnology (in press).

Otros artículos de Carla C. C. R. de Carvalho

De Carvalho CCCR, Da Fonseca MMR. Biotransformation of terpenes, Biotechnology Advances (in press).

De Carvalho CCCR, Da Fonseca MMR. The remarkable Rhodococcus erythropolis (Review) Applied Microbiology and Biotechnology 2005; 67(6):715-726.

De Carvalho CCCR, Da Fonseca MMR. Degradation of hydrocarbons and alcohols at different temperatures and salinities by Rhodococcus erythropolis DCL14, FEMS Microbiology Ecology 2005; 51:389-399.

De Carvalho CCCR, Parreño Marchante B, Neumann G, Da Fonseca MMR, Heipieper HJ. Adaptation of Rhodococcus erythropolis DCL14 to growth on n-alkanes, alcohols and terpenes. Applied Microbiology and Biotechnology 2005; 67(3):383-388.

De Carvalho CCCR, Pons MN, Da Fonseca MMR. Principal components analysis as a tool to summarise biotransformation data: Influence on cells of solvent type and phase ratio, Biocatalysis and Biotransformation 2003; 21(6):305-314.

De Carvalho CCCR, Da Fonseca MMR. Towards the bio-production of trans-carveol and carvone from limonene: induction after cell growth on limonene and toluene. Tetrahedron: Asymmetry 14:3925-3931.

De Carvalho CCCR, Da Fonseca MMR. Influence of reactor configuration on the production of carvone from carveol by wehole cells of Rhodococcus erythropolis DCL14. Journal of Molecular Catalysis B: Enzymatic, 19-20C, 377-387.

De Carvalho CCCR, Da Fonseca MMR. Maintenance of cell viability in the biotransformation of (-)-carveol with whole cells of Rhodococcus erythropolis. Journal of Molecular Catalysis B: Enzymatic, 19-20C, 389-398.

De Carvalho CCCR, Van Keulen F, Da Fonseca MMR. Modelling the bio-kinetic resolution of diastereomers present in unequal initial amounts, Tetrahedron: Asymmetry 13(15):1637-1643.

De Carvalho CCCR, Van Keulen F, Da Fonseca MMR. Production and recovery of limonene-1,2-diol and simultaneous resolution of a diastereomeric mixture of limonene-1,2-epoxide with whole cells of Rhodococcus erythropolis DCL14, Biocatalysis and Biotransformation 18:223-235.

Para comunicarse con Carla C. C. R. de Carvalho mencionar a SIIC como referencia:

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Acerca del trabajo completo

CARVONA: PORQUÊ E COMO PRODUZIR ESTE TERPENO

Título original en castellano
CARVONA: PORQUÊ E COMO DEVE ALGUEM INCOMODAR-SE A PRODUZIR ESTE TERPENO

Autor
Carla C. C. R. de Carvalho¹
1 Ingeniera Química, Centro de Engenharia Biológica e Química, Instituto Superior Técnico, Investigadora de Pós-doutoramento

Acceso a la fuente original
Food Chemistry
http://www.elsevier.com/locate/foodchem

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